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Meanwhile, ethical approval of this research was approved by the Ethics Committee of Institutional Animal Care and Use Committee of the Second Hospital of Shandong University to the National Institutes of Health (NIH) guidelines for the Care and use of Laboratory Animals(Ethics approval No. KYLL-2022LW157).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval and Consent to Participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}}]}}