{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T18:12:51Z","timestamp":1789409571539,"version":"build-2803163510"},"reference-count":211,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T00:00:00Z","timestamp":1716854400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T00:00:00Z","timestamp":1716854400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neurochem Res"],"published-print":{"date-parts":[[2024,8]]},"DOI":"10.1007\/s11064-024-04157-1","type":"journal-article","created":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T20:36:11Z","timestamp":1716928571000},"page":"1905-1925","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Advances in Exosome-Based Therapies for the Repair of Peripheral Nerve Injuries"],"prefix":"10.1007","volume":"49","author":[{"given":"Sana","family":"Rahimian","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hossein","family":"Najafi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine A.","family":"Webber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanieh","family":"Jalali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,5,28]]},"reference":[{"key":"4157_CR1","doi-asserted-by":"publisher","first-page":"1098612","DOI":"10.3389\/fnins.2023.1098612","volume":"17","author":"L Zhao","year":"2023","unstructured":"Zhao L, Huang W, Yi S (2023) Cellular complexity of the peripheral nervous system: insights from single-cell resolution. Front Neurosci 17:1098612","journal-title":"Front Neurosci"},{"key":"4157_CR2","doi-asserted-by":"crossref","unstructured":"Bianchini M, Micera S, Redolfi Riva E (2023) Recent advances in polymeric drug delivery systems for peripheral nerve regeneration. Pharmaceutics 15","DOI":"10.3390\/pharmaceutics15020640"},{"key":"4157_CR3","doi-asserted-by":"publisher","first-page":"587699","DOI":"10.3389\/fcell.2020.587699","volume":"8","author":"S Vermeiren","year":"2020","unstructured":"Vermeiren S, Bellefroid EJ, Desiderio S (2020) Vertebrate sensory ganglia: common and divergent features of the transcriptional programs generating their functional specialization. Front Cell Dev Biol 8:587699","journal-title":"Front Cell Dev Biol"},{"key":"4157_CR4","doi-asserted-by":"crossref","unstructured":"Koppes AN, Thompson DM (2015) 12 - neural innervation of engineered musculoskeletal tissues. In: Nukavarapu SP, Freeman JW, Laurencin CT (eds) Regenerative engineering of musculoskeletal tissues and interfaces. Woodhead Publishing, pp 293\u2013323","DOI":"10.1016\/B978-1-78242-301-0.00012-4"},{"key":"4157_CR5","doi-asserted-by":"publisher","first-page":"116","DOI":"10.7150\/ijbs.35653","volume":"16","author":"G Hussain","year":"2020","unstructured":"Hussain G, Wang J, Rasul A, Anwar H, Qasim M, Zafar S, Aziz N, Razzaq A, Hussain R, de Aguilar JG, Sun T (2020) Current status of therapeutic approaches against peripheral nerve injuries: a detailed story from injury to recovery. Int J Biol Sci 16:116\u2013134","journal-title":"Int J Biol Sci"},{"key":"4157_CR6","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1177\/1558944720963895","volume":"17","author":"WM Padovano","year":"2022","unstructured":"Padovano WM, Dengler J, Patterson MM, Yee A, Snyder-Warwick AK, Wood MD, Moore AM, Mackinnon SE (2022) Incidence of nerve injury after extremity trauma in the United States. Hand (N Y) 17:615\u2013623","journal-title":"Hand (N Y)"},{"key":"4157_CR7","doi-asserted-by":"crossref","unstructured":"Maeng WY, Tseng WL, Li S, Koo J, Hsueh YY (2022) Electroceuticals for peripheral nerve regeneration. Biofabrication 14","DOI":"10.1088\/1758-5090\/ac8baa"},{"key":"4157_CR8","doi-asserted-by":"crossref","unstructured":"Gordon T (2020) Peripheral nerve regeneration and muscle reinnervation. Int J Mol Sci 21","DOI":"10.3390\/ijms21228652"},{"key":"4157_CR9","doi-asserted-by":"publisher","first-page":"332","DOI":"10.34172\/jlms.2020.54","volume":"11","author":"LL Sasso","year":"2020","unstructured":"Sasso LL, de Souza LG, Girasol CE, Marcolino AM, de Jesus Guirro RR, Barbosa RI (2020) Photobiomodulation in sciatic nerve crush injuries in rodents: a systematic review of the literature and perspectives for clinical treatment. J Lasers Med Sci 11:332\u2013344","journal-title":"J Lasers Med Sci"},{"key":"4157_CR10","doi-asserted-by":"crossref","unstructured":"Dias FJ, Issa JP, Iyomasa MM, Coutinho-Netto J, Calzzani RA, Iyomasa DM, Sousa LG, de Almeida SR, Cury DP, Watanabe IS (2013) Application of a low-level laser therapy and the purified protein from natural latex (Hevea brasiliensis) in the controlled crush injury of the sciatic nerve of rats: a morphological, quantitative, and ultrastructural study. Biomed Res Int 2013:597863","DOI":"10.1155\/2013\/597863"},{"key":"4157_CR11","doi-asserted-by":"publisher","first-page":"544","DOI":"10.1007\/s12015-021-10236-5","volume":"18","author":"L Jiang","year":"2022","unstructured":"Jiang L, Mee T, Zhou X, Jia X (2022) Augmenting peripheral nerve regeneration with adipose-derived stem cells. Stem Cell Rev Rep 18:544\u2013558","journal-title":"Stem Cell Rev Rep"},{"key":"4157_CR12","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1016\/j.neuron.2017.03.034","volume":"94","author":"YL Weng","year":"2017","unstructured":"Weng YL, An R, Cassin J, Joseph J, Mi R, Wang C, Zhong C, Jin SG, Pfeifer GP, Bellacosa A, Dong X, Hoke A, He Z, Song H, Ming GL (2017) An intrinsic epigenetic barrier for functional Axon Regeneration. Neuron 94:337\u2013346e336","journal-title":"Neuron"},{"key":"4157_CR13","doi-asserted-by":"crossref","unstructured":"Dong R, Liu Y, Yang Y, Wang H, Xu Y, Zhang Z (2019) MSC-derived exosomes-based therapy for peripheral nerve injury: a novel therapeutic strategy. Biomed Res Int 2019:6458237","DOI":"10.1155\/2019\/6458237"},{"key":"4157_CR14","doi-asserted-by":"crossref","unstructured":"Juckett L, Saffari TM, Ormseth B, Senger JL, Moore AM (2022) The effect of electrical stimulation on nerve regeneration following peripheral nerve Injury. Biomolecules 12","DOI":"10.3390\/biom12121856"},{"key":"4157_CR15","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.hcl.2015.12.002","volume":"32","author":"SK Trehan","year":"2016","unstructured":"Trehan SK, Model Z, Lee SK (2016) Nerve repair and nerve grafting. Hand Clin 32:119\u2013125","journal-title":"Hand Clin"},{"issue":"Suppl 4","key":"4157_CR16","doi-asserted-by":"publisher","first-page":"S222","DOI":"10.1097\/SAP.0000000000000373","volume":"74","author":"B Rinker","year":"2015","unstructured":"Rinker B (2015) Nerve transfers in the Upper Extremity: a practical user\u2019s guide. Ann Plast Surg 74(Suppl 4):S222\u2013228","journal-title":"Ann Plast Surg"},{"key":"4157_CR17","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1007\/s00590-018-2344-2","volume":"29","author":"A Beris","year":"2019","unstructured":"Beris A, Gkiatas I, Gelalis I, Papadopoulos D, Kostas-Agnantis I (2019) Current concepts in peripheral nerve surgery. Eur J Orthop Surg Traumatol 29:263\u2013269","journal-title":"Eur J Orthop Surg Traumatol"},{"key":"4157_CR18","doi-asserted-by":"publisher","first-page":"1289","DOI":"10.1038\/s41401-019-0338-1","volume":"41","author":"R Li","year":"2020","unstructured":"Li R, Li DH, Zhang HY, Wang J, Li XK, Xiao J (2020) Growth factors-based therapeutic strategies and their underlying signaling mechanisms for peripheral nerve regeneration. Acta Pharmacol Sin 41:1289\u20131300","journal-title":"Acta Pharmacol Sin"},{"key":"4157_CR19","doi-asserted-by":"crossref","unstructured":"Jiang L, Jones S, Jia X (2017) Stem cell transplantation for peripheral nerve regeneration: current options and opportunities. Int J Mol Sci 18","DOI":"10.3390\/ijms18010094"},{"key":"4157_CR20","doi-asserted-by":"crossref","unstructured":"Jones S, Eisenberg HM, Jia X (2016) Advances and future applications of augmented peripheral nerve regeneration. Int J Mol Sci 17","DOI":"10.3390\/ijms17091494"},{"key":"4157_CR21","doi-asserted-by":"publisher","first-page":"e1701164","DOI":"10.1002\/adhm.201701164","volume":"7","author":"PA Wieringa","year":"2018","unstructured":"Wieringa PA, Gon\u00e7alves de Pinho AR, Micera S, van Wezel RJA, Moroni L (2018) Biomimetic architectures for peripheral nerve repair: a review of Biofabrication strategies. Adv Healthc Mater 7:e1701164","journal-title":"Adv Healthc Mater"},{"key":"4157_CR22","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1007\/978-981-13-0947-2_27","volume":"1077","author":"R Ashraf","year":"2018","unstructured":"Ashraf R, Sofi HS, Beigh MA, Majeed S, Arjamand S, Sheikh FA (2018) Prospects of natural polymeric scaffolds in peripheral nerve tissue-regeneration. Adv Exp Med Biol 1077:501\u2013525","journal-title":"Adv Exp Med Biol"},{"key":"4157_CR23","doi-asserted-by":"publisher","first-page":"105952","DOI":"10.1016\/j.nbd.2022.105952","volume":"176","author":"M Bosch-Queralt","year":"2023","unstructured":"Bosch-Queralt M, Fledrich R, Stassart RM (2023) Schwann cell functions in peripheral nerve development and repair. Neurobiol Dis 176:105952","journal-title":"Neurobiol Dis"},{"key":"4157_CR24","doi-asserted-by":"publisher","first-page":"3977","DOI":"10.1007\/s00018-020-03516-9","volume":"77","author":"G Nocera","year":"2020","unstructured":"Nocera G, Jacob C (2020) Mechanisms of Schwann cell plasticity involved in peripheral nerve repair after injury. Cell Mol Life Sci 77:3977\u20133989","journal-title":"Cell Mol Life Sci"},{"key":"4157_CR25","doi-asserted-by":"publisher","first-page":"E2","DOI":"10.3171\/2016.12.FOCUS16474","volume":"42","author":"ZC Gersey","year":"2017","unstructured":"Gersey ZC, Burks SS, Anderson KD, Dididze M, Khan A, Dietrich WD, Levi AD (2017) First human experience with autologous Schwann cells to supplement sciatic nerve repair: report of 2 cases with long-term follow-up. Neurosurg Focus 42:E2","journal-title":"Neurosurg Focus"},{"key":"4157_CR26","doi-asserted-by":"publisher","first-page":"23097","DOI":"10.1002\/jcp.28873","volume":"234","author":"J Chen","year":"2019","unstructured":"Chen J, Ren S, Duscher D, Kang Y, Liu Y, Wang C, Yuan M, Guo G, Xiong H, Zhan P, Wang Y, Machens HG, Chen Z (2019) Exosomes from human adipose-derived stem cells promote sciatic nerve regeneration via optimizing Schwann cell function. J Cell Physiol 234:23097\u201323110","journal-title":"J Cell Physiol"},{"key":"4157_CR27","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1186\/s13287-021-02690-2","volume":"13","author":"X Li","year":"2022","unstructured":"Li X, Guan Y, Li C, Zhang T, Meng F, Zhang J, Li J, Chen S, Wang Q, Wang Y, Peng J, Tang J (2022) Immunomodulatory effects of mesenchymal stem cells in peripheral nerve injury. Stem Cell Res Ther 13:18","journal-title":"Stem Cell Res Ther"},{"key":"4157_CR28","doi-asserted-by":"publisher","first-page":"318e","DOI":"10.1097\/01.prs.0000475762.86580.36","volume":"137","author":"Y Sowa","year":"2016","unstructured":"Sowa Y, Kishida T, Imura T, Numajiri T, Nishino K, Tabata Y, Mazda O (2016) Adipose-derived stem cells promote peripheral nerve regeneration in vivo without differentiation into Schwann-Like Lineage. Plast Reconstr Surg 137:318e\u2013330e","journal-title":"Plast Reconstr Surg"},{"key":"4157_CR29","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1186\/s13287-020-01661-3","volume":"11","author":"LN Zhou","year":"2020","unstructured":"Zhou LN, Wang JC, Zilundu PLM, Wang YQ, Guo WP, Zhang SX, Luo H, Zhou JH, Deng RD, Chen DF (2020) A comparison of the use of adipose-derived and bone marrow-derived stem cells for peripheral nerve regeneration in vitro and in vivo. Stem Cell Res Ther 11:153","journal-title":"Stem Cell Res Ther"},{"key":"4157_CR30","doi-asserted-by":"publisher","first-page":"189","DOI":"10.26502\/jbb.2642-91280082","volume":"6","author":"R Supra","year":"2023","unstructured":"Supra R, Wilson DR, Agrawal DK (2023) Therapeutic potential of smart exosomes in peripheral nerve regeneration. J Biotechnol Biomed 6:189\u2013196","journal-title":"J Biotechnol Biomed"},{"key":"4157_CR31","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1208\/s12248-017-0160-y","volume":"20","author":"A Jeyaram","year":"2017","unstructured":"Jeyaram A, Jay SM (2017) Preservation and storage stability of extracellular vesicles for therapeutic applications. Aaps J 20:1","journal-title":"Aaps j"},{"key":"4157_CR32","doi-asserted-by":"crossref","unstructured":"Mas-Bargues C, Alique M (2023) Extracellular vesicles as very important particles (VIPs) in aging. Int J Mol Sci 24","DOI":"10.3390\/ijms24044250"},{"key":"4157_CR33","doi-asserted-by":"crossref","unstructured":"Th\u00e9ry C, Witwer KW, Aikawa E, Alcaraz MJ, Anderson JD, et al. (2018) Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the international society for extracellular vesicles and update of the MISEV2014 guidelines. J Extracell Vesicles 7:1535750","DOI":"10.1080\/20013078.2018.1535750"},{"key":"4157_CR34","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1007\/s00018-017-2595-9","volume":"75","author":"NP Hessvik","year":"2018","unstructured":"Hessvik NP, Llorente A (2018) Current knowledge on exosome biogenesis and release. Cell Mol Life Sci 75:193\u2013208","journal-title":"Cell Mol Life Sci"},{"key":"4157_CR35","doi-asserted-by":"publisher","first-page":"849905","DOI":"10.3389\/fcell.2022.849905","volume":"10","author":"PN Avalos","year":"2022","unstructured":"Avalos PN, Forsthoefel DJ (2022) An emerging frontier in intercellular communication: extracellular vesicles in regeneration. Front Cell Dev Biol 10:849905","journal-title":"Front Cell Dev Biol"},{"key":"4157_CR36","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1111\/j.1365-2249.2010.04271.x","volume":"163","author":"S Sadallah","year":"2011","unstructured":"Sadallah S, Eken C, Schifferli JA (2011) Ectosomes as modulators of inflammation and immunity. Clin Exp Immunol 163:26\u201332","journal-title":"Clin Exp Immunol"},{"key":"4157_CR37","doi-asserted-by":"publisher","first-page":"721","DOI":"10.3389\/fimmu.2018.00721","volume":"9","author":"E Karasu","year":"2018","unstructured":"Karasu E, Eisenhardt SU, Harant J, Huber-Lang M (2018) Extracellular vesicles: packages sent with complement. Front Immunol 9:721","journal-title":"Front Immunol"},{"key":"4157_CR38","doi-asserted-by":"publisher","first-page":"3395","DOI":"10.2147\/JIR.S362865","volume":"15","author":"W Wei","year":"2022","unstructured":"Wei W, Pan Y, Yang X, Chen Z, Heng Y, Yang B, Pu M, Zuo J, Lai Z, Tang Y, Xin W (2022) The emerging role of the interaction of extracellular vesicle and autophagy-novel insights into neurological disorders. J Inflamm Res 15:3395\u20133407","journal-title":"J Inflamm Res"},{"key":"4157_CR39","doi-asserted-by":"publisher","first-page":"534","DOI":"10.1038\/aps.2018.17","volume":"39","author":"W Sun","year":"2018","unstructured":"Sun W, Luo JD, Jiang H, Duan DD (2018) Tumor exosomes: a double-edged sword in cancer therapy. Acta Pharmacol Sin 39:534\u2013541","journal-title":"Acta Pharmacol Sin"},{"key":"4157_CR40","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1016\/j.jri.2016.08.008","volume":"119","author":"D Tannetta","year":"2017","unstructured":"Tannetta D, Masliukaite I, Vatish M, Redman C, Sargent I (2017) Update of syncytiotrophoblast derived extracellular vesicles in normal pregnancy and preeclampsia. J Reprod Immunol 119:98\u2013106","journal-title":"J Reprod Immunol"},{"key":"4157_CR41","doi-asserted-by":"publisher","first-page":"945","DOI":"10.1039\/C6CC07879F","volume":"53","author":"R Subiros-Funosas","year":"2017","unstructured":"Subiros-Funosas R, Mendive-Tapia L, Sot J, Pound JD, Barth N, Varela Y, Go\u00f1i FM, Paterson M, Gregory CD, Albericio F, Dransfield I, Lavilla R, Vendrell M (2017) A Trp-BODIPY cyclic peptide for fluorescence labelling of apoptotic bodies. Chem Commun (Camb) 53:945\u2013948","journal-title":"Chem Commun (Camb)"},{"key":"4157_CR42","doi-asserted-by":"crossref","unstructured":"Kalluri R, LeBleu VS (2020) The biology, function, and biomedical applications of exosomes. Science 367","DOI":"10.1126\/science.aau6977"},{"key":"4157_CR43","doi-asserted-by":"publisher","first-page":"3037","DOI":"10.4049\/jimmunol.170.6.3037","volume":"170","author":"D Skokos","year":"2003","unstructured":"Skokos D, Botros HG, Demeure C, Morin J, Peronet R, Birkenmeier G, Boudaly S, M\u00e9cheri S (2003) Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo. J Immunol 170:3037\u20133045","journal-title":"J Immunol"},{"key":"4157_CR44","doi-asserted-by":"publisher","first-page":"e97580","DOI":"10.1371\/journal.pone.0097580","volume":"9","author":"S Dutta","year":"2014","unstructured":"Dutta S, Warshall C, Bandyopadhyay C, Dutta D, Chandran B (2014) Interactions between exosomes from breast Cancer cells and primary mammary epithelial cells leads to generation of reactive oxygen species which induce DNA damage response, stabilization of p53 and autophagy in epithelial cells. PLoS ONE 9:e97580","journal-title":"PLoS ONE"},{"key":"4157_CR45","doi-asserted-by":"publisher","first-page":"1876","DOI":"10.1021\/acs.jproteome.2c00159","volume":"21","author":"J Zhang","year":"2022","unstructured":"Zhang J, Qin Y, Jiang Q, Li F, Jing X, Cao L, Cai S, Wu F, Li Q, Lian J, Song Y, Huang C (2022) Glycopattern alteration of glycoproteins in gastrointestinal cancer cell lines and their cell-derived exosomes. J Proteome Res 21:1876\u20131893","journal-title":"J Proteome Res"},{"key":"4157_CR46","doi-asserted-by":"publisher","first-page":"11497","DOI":"10.1038\/s41598-019-47760-x","volume":"9","author":"A Shimoda","year":"2019","unstructured":"Shimoda A, Sawada SI, Sasaki Y, Akiyoshi K (2019) Exosome surface glycans reflect osteogenic differentiation of mesenchymal stem cells: profiling by an evanescent field fluorescence-assisted lectin array system. Sci Rep 9:11497","journal-title":"Sci Rep"},{"key":"4157_CR47","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1080\/01478885.2019.1646984","volume":"42","author":"F Deng","year":"2019","unstructured":"Deng F, Miller J (2019) A review on protein markers of exosome from different bio-resources and the antibodies used for characterization. J Histotechnol 42:226\u2013239","journal-title":"J Histotechnol"},{"key":"4157_CR48","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1038\/s41580-022-00460-3","volume":"23","author":"G van Niel","year":"2022","unstructured":"van Niel G, Carter DRF, Clayton A, Lambert DW, Raposo G, Vader P (2022) Challenges and directions in studying cell-cell communication by extracellular vesicles. Nat Rev Mol Cell Biol 23:369\u2013382","journal-title":"Nat Rev Mol Cell Biol"},{"key":"4157_CR49","doi-asserted-by":"publisher","first-page":"240","DOI":"10.3389\/fnmol.2019.00240","volume":"12","author":"W Liu","year":"2019","unstructured":"Liu W, Bai X, Zhang A, Huang J, Xu S, Zhang J (2019) Role of exosomes in central nervous system diseases. Front Mol Neurosci 12:240","journal-title":"Front Mol Neurosci"},{"key":"4157_CR50","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1186\/s12967-022-03493-6","volume":"20","author":"Y Fan","year":"2022","unstructured":"Fan Y, Chen Z, Zhang M (2022) Role of exosomes in the pathogenesis, diagnosis, and treatment of central nervous system diseases. J Translational Med 20:291","journal-title":"J Translational Med"},{"key":"4157_CR51","doi-asserted-by":"crossref","unstructured":"Xie S, Zhang Q, Jiang L (2022) Current knowledge on exosome biogenesis, cargo-sorting mechanism and therapeutic implications. Membranes (Basel) 12","DOI":"10.3390\/membranes12050498"},{"key":"4157_CR52","doi-asserted-by":"publisher","first-page":"152","DOI":"10.3390\/genes4020152","volume":"4","author":"L Urbanelli","year":"2013","unstructured":"Urbanelli L, Magini A, Buratta S, Brozzi A, Sagini K, Polchi A, Tancini B, Emiliani C (2013) Signaling pathways in exosomes biogenesis, secretion and fate. Genes (Basel) 4:152\u2013170","journal-title":"Genes (Basel)"},{"key":"4157_CR53","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1038\/s41422-020-00418-0","volume":"31","author":"CM Kenific","year":"2021","unstructured":"Kenific CM, Zhang H, Lyden D (2021) An exosome pathway without an ESCRT. Cell Res 31:105\u2013106","journal-title":"Cell Res"},{"key":"4157_CR54","doi-asserted-by":"crossref","unstructured":"Foo JB, Looi QH, How CW, Lee SH, Al-Masawa ME, Chong PP, Law JX (2021) Mesenchymal stem cell-derived exosomes and microRNAs in cartilage regeneration: biogenesis, efficacy, miRNA enrichment and delivery. Pharmaceuticals (Basel) 14","DOI":"10.3390\/ph14111093"},{"key":"4157_CR55","doi-asserted-by":"crossref","unstructured":"Gurunathan S, Kang MH, Jeyaraj M, Qasim M, Kim JH (2019) Review of the isolation, characterization, biological function, and multifarious therapeutic approaches of exosomes. Cells 8","DOI":"10.3390\/cells8040307"},{"key":"4157_CR56","doi-asserted-by":"publisher","first-page":"4041","DOI":"10.1172\/JCI129193","volume":"129","author":"S Kita","year":"2019","unstructured":"Kita S, Maeda N, Shimomura I (2019) Interorgan communication by exosomes, adipose tissue, and adiponectin in metabolic syndrome. J Clin Invest 129:4041\u20134049","journal-title":"J Clin Invest"},{"key":"4157_CR57","doi-asserted-by":"crossref","unstructured":"Lau NCH, Yam JWP (2023) From Exosome Biogenesis to absorption: key takeaways for cancer research. Cancers (Basel) 15","DOI":"10.3390\/cancers15071992"},{"key":"4157_CR58","doi-asserted-by":"publisher","first-page":"4078","DOI":"10.1038\/s41467-022-31713-6","volume":"13","author":"L Guan","year":"2022","unstructured":"Guan L, Wu B, Li T, Beer LA, Sharma G, Li M, Lee CN, Liu S, Yang C, Huang L, Frederick DT, Boland GM, Shao G, Svitkina TM, Cai KQ, Chen F, Dong M-Q, Mills GB, Schuchter LM, Karakousis GC, Mitchell TC, Flaherty KT, Speicher DW, Chen YH, Herlyn M, Amaravadi RK, Xu X, Guo W (2022) HRS phosphorylation drives immunosuppressive exosome secretion and restricts CD8\u2009+\u2009T-cell infiltration into tumors. Nat Commun 13:4078","journal-title":"Nat Commun"},{"key":"4157_CR59","doi-asserted-by":"publisher","first-page":"1140","DOI":"10.1016\/j.cell.2020.07.021","volume":"182","author":"A-K Pfitzner","year":"2020","unstructured":"Pfitzner A-K, Mercier V, Jiang X, Moser von Filseck J, Baum B, \u0160ari\u0107 A, Roux A (2020) An ESCRT-III polymerization sequence drives membrane deformation and fission. Cell 182:1140\u20131155e1118","journal-title":"Cell"},{"key":"4157_CR60","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/j.semcancer.2014.04.009","volume":"28","author":"C Villarroya-Beltri","year":"2014","unstructured":"Villarroya-Beltri C, Baixauli F, Guti\u00e9rrez-V\u00e1zquez C, S\u00e1nchez-Madrid F, Mittelbrunn M (2014) Sorting it out: regulation of exosome loading. Sem Cancer Biol 28:3\u201313","journal-title":"Sem Cancer Biol"},{"key":"4157_CR61","doi-asserted-by":"publisher","first-page":"722581","DOI":"10.3389\/fimmu.2021.722581","volume":"12","author":"M Abdullah","year":"2021","unstructured":"Abdullah M, Nakamura T, Ferdous T, Gao Y, Chen Y, Zou K, Michikawa M (2021) Cholesterol regulates exosome release in cultured astrocytes. Front Immunol 12:722581","journal-title":"Front Immunol"},{"key":"4157_CR62","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/bs.acr.2018.05.004","volume":"140","author":"A Elsherbini","year":"2018","unstructured":"Elsherbini A, Bieberich E (2018) Ceramide and exosomes: a Novel target in cancer biology and therapy. Adv Cancer Res 140:121\u2013154","journal-title":"Adv Cancer Res"},{"key":"4157_CR63","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1111\/tra.12803","volume":"22","author":"J Donoso-Quezada","year":"2021","unstructured":"Donoso-Quezada J, Ayala-Mar S, Gonz\u00e1lez-Valdez J (2021) The role of lipids in exosome biology and intercellular communication: function, analytics and applications. Traffic 22:204\u2013220","journal-title":"Traffic"},{"key":"4157_CR64","doi-asserted-by":"crossref","unstructured":"Horbay R, Hamraghani A, Ermini L, Holcik S, Beug ST, Yeganeh B (2022) Role of ceramides and lysosomes in extracellular vesicle biogenesis, cargo sorting and release. Int J Mol Sci 23","DOI":"10.3390\/ijms232315317"},{"key":"4157_CR65","doi-asserted-by":"publisher","first-page":"1244","DOI":"10.1126\/science.1153124","volume":"319","author":"K Trajkovic","year":"2008","unstructured":"Trajkovic K, Hsu C, Chiantia S, Rajendran L, Wenzel D, Wieland F, Schwille P, Br\u00fcgger B, Simons M (2008) Ceramide triggers budding of exosome vesicles into multivesicular endosomes. Science 319:1244\u20131247","journal-title":"Science"},{"key":"4157_CR66","doi-asserted-by":"crossref","unstructured":"Jankovi\u010dov\u00e1 J, Se\u010dov\u00e1 P, Michalkov\u00e1 K, Antal\u00edkov\u00e1 J (2020) Tetraspanins, more than markers of extracellular vesicles in reproduction. Int J Mol Sci 21","DOI":"10.3390\/ijms21207568"},{"key":"4157_CR67","doi-asserted-by":"publisher","first-page":"8822","DOI":"10.1038\/s41598-018-27180-z","volume":"8","author":"JS Brzozowski","year":"2018","unstructured":"Brzozowski JS, Bond DR, Jankowski H, Goldie BJ, Burchell R, Naudin C, Smith ND, Scarlett CJ, Larsen MR, Dun MD, Skelding KA, Weidenhofer J (2018) Extracellular vesicles with altered tetraspanin CD9 and CD151 levels confer increased prostate cell motility and invasion. Sci Rep 8:8822","journal-title":"Sci Rep"},{"key":"4157_CR68","doi-asserted-by":"publisher","first-page":"1079","DOI":"10.1083\/jcb.201002049","volume":"190","author":"A Chairoungdua","year":"2010","unstructured":"Chairoungdua A, Smith DL, Pochard P, Hull M, Caplan MJ (2010) Exosome release of \u03b2-catenin: a novel mechanism that antagonizes wnt signaling. J Cell Biol 190:1079\u20131091","journal-title":"J Cell Biol"},{"key":"4157_CR69","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1080\/21541248.2016.1251378","volume":"9","author":"V Hyenne","year":"2018","unstructured":"Hyenne V, Labouesse M, Goetz JG (2018) The small GTPase ral orchestrates MVB biogenesis and exosome secretion. Small GTPases 9:445\u2013451","journal-title":"Small GTPases"},{"key":"4157_CR70","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1038\/nrm2728","volume":"10","author":"H Stenmark","year":"2009","unstructured":"Stenmark H (2009) Rab GTPases as coordinators of vesicle traffic. Nat Rev Mol Cell Biol 10:513\u2013525","journal-title":"Nat Rev Mol Cell Biol"},{"key":"4157_CR71","doi-asserted-by":"crossref","unstructured":"Margiotta A (2022) Membrane fusion and SNAREs: interaction with Ras proteins. Int J Mol Sci 23","DOI":"10.3390\/ijms23158067"},{"key":"4157_CR72","doi-asserted-by":"publisher","first-page":"1334","DOI":"10.1016\/j.jmb.2008.01.099","volume":"377","author":"O Pylypenko","year":"2008","unstructured":"Pylypenko O, Sch\u00f6nichen A, Ludwig D, Ungermann C, Goody RS, Rak A, Geyer M (2008) Farnesylation of the SNARE protein Ykt6 increases its stability and helical folding. J Mol Biol 377:1334\u20131345","journal-title":"J Mol Biol"},{"key":"4157_CR73","doi-asserted-by":"publisher","first-page":"767","DOI":"10.1111\/tra.12524","volume":"18","author":"T Wang","year":"2017","unstructured":"Wang T, Li L, Hong W (2017) SNARE proteins in membrane trafficking. Traffic 18:767\u2013775","journal-title":"Traffic"},{"key":"4157_CR74","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1007\/s00018-023-04822-8","volume":"80","author":"NP Hessvik","year":"2023","unstructured":"Hessvik NP, Sagini K, Romero S, Ramirez-Garrastacho M, Rodriguez M, Tutturen AEV, Kvalvaag A, Stang E, Brech A, Sandvig K, Llorente A (2023) siRNA screening reveals that SNAP29 contributes to exosome release. Cell Mol Life Sci 80:177","journal-title":"Cell Mol Life Sci"},{"key":"4157_CR75","first-page":"1397","volume":"1865","author":"I Kjos","year":"2018","unstructured":"Kjos I, Vestre K, Guadagno NA, Borg Distefano M, Progida C (2018) Rab and Arf proteins at the crossroad between membrane transport and cytoskeleton dynamics. Biochimica et Biophysica Acta (BBA). Mol Cell Res 1865:1397\u20131409","journal-title":"Mol Cell Res"},{"key":"4157_CR76","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1134\/S0006297923040028","volume":"88","author":"AA Yakovlev","year":"2023","unstructured":"Yakovlev AA (2023) Neuronal exosomes as a new signaling system. Biochem (Mosc) 88:457\u2013465","journal-title":"Biochem (Mosc)"},{"key":"4157_CR77","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1038\/ncb2000","volume":"12","author":"M Ostrowski","year":"2010","unstructured":"Ostrowski M, Carmo NB, Krumeich S, Fanget I, Raposo G, Savina A, Moita CF, Schauer K, Hume AN, Freitas RP, Goud B, Benaroch P, Hacohen N, Fukuda M, Desnos C, Seabra MC, Darchen F, Amigorena S, Moita LF, Thery C (2010) Rab27a and Rab27b control different steps of the exosome secretion pathway. Nat Cell Biol 12:19\u201330 sup pp 11\u201313","journal-title":"Nat Cell Biol"},{"key":"4157_CR78","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1083\/jcb.201601025","volume":"214","author":"S Sinha","year":"2016","unstructured":"Sinha S, Hoshino D, Hong NH, Kirkbride KC, Grega-Larson NE, Seiki M, Tyska MJ, Weaver AM (2016) Cortactin promotes exosome secretion by controlling branched actin dynamics. J Cell Biol 214:197\u2013213","journal-title":"J Cell Biol"},{"key":"4157_CR79","doi-asserted-by":"publisher","first-page":"867","DOI":"10.1111\/jnc.13565","volume":"137","author":"AM C\u00e1rdenas","year":"2016","unstructured":"C\u00e1rdenas AM, Marengo FD (2016) How the stimulus defines the dynamics of vesicle pool recruitment, fusion mode, and vesicle recycling in neuroendocrine cells. J Neurochem 137:867\u2013879","journal-title":"J Neurochem"},{"key":"4157_CR80","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1152\/physiol.00012.2006","volume":"21","author":"LI Cosen-Binker","year":"2006","unstructured":"Cosen-Binker LI, Kapus A (2006) Cortactin: the Gray Eminence of the cytoskeleton. Physiology 21:352\u2013361","journal-title":"Physiology"},{"key":"4157_CR81","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1083\/jcb.201505011","volume":"210","author":"Y Kubo","year":"2015","unstructured":"Kubo Y, Baba K, Toriyama M, Minegishi T, Sugiura T, Kozawa S, Ikeda K, Inagaki N (2015) Shootin1\u2013cortactin interaction mediates signal\u2013force transduction for axon outgrowth. J Cell Biol 210:663\u2013676","journal-title":"J Cell Biol"},{"key":"4157_CR82","doi-asserted-by":"publisher","first-page":"130","DOI":"10.3389\/fncel.2017.00130","volume":"11","author":"AM Gonz\u00e1lez-Jamett","year":"2017","unstructured":"Gonz\u00e1lez-Jamett AM, Guerra MJ, Olivares MJ, Haro-Acu\u00f1a V, Ba\u00e9z-Matus X, V\u00e1squez-Navarrete J, Momboisse F, Martinez-Quiles N, C\u00e1rdenas AM (2017) The F-Actin binding protein cortactin regulates the dynamics of the exocytotic fusion pore through its SH3 domain. Front Cell Neurosci 11:130","journal-title":"Front Cell Neurosci"},{"key":"4157_CR83","doi-asserted-by":"crossref","unstructured":"Jaiswal R, Sedger LM (2019) Intercellular vesicular transfer by exosomes, microparticles and oncosomes - implications for cancer biology and treatments. Front Oncol 9","DOI":"10.3389\/fonc.2019.00125"},{"key":"4157_CR84","doi-asserted-by":"publisher","first-page":"1301","DOI":"10.1016\/j.bpj.2023.02.025","volume":"122","author":"A Mahmood","year":"2023","unstructured":"Mahmood A, Otruba Z, Weisgerber AW, Palay MD, Nguyen MT, Bills BL, Knowles MK (2023) Exosome secretion kinetics are controlled by temperature. Biophys J 122:1301\u20131314","journal-title":"Biophys J"},{"key":"4157_CR85","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1080\/02656736.2022.2029585","volume":"39","author":"D Xu","year":"2022","unstructured":"Xu D, Tang WJ, Zhu YZ, Liu Z, Yang K, Liang MX, Chen X, Wu Y, Tang JH, Zhang W (2022) Hyperthermia promotes exosome secretion by regulating Rab7b while increasing drug sensitivity in adriamycin-resistant breast cancer. Int J Hyperth 39:246\u2013257","journal-title":"Int J Hyperth"},{"key":"4157_CR86","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1016\/j.actbio.2019.12.020","volume":"103","author":"W Liu","year":"2020","unstructured":"Liu W, Li L, Rong Y, Qian D, Chen J, Zhou Z, Luo Y, Jiang D, Cheng L, Zhao S, Kong F, Wang J, Zhou Z, Xu T, Gong F, Huang Y, Gu C, Zhao X, Bai J, Wang F, Zhao W, Zhang L, Li X, Yin G, Fan J, Cai W (2020) Hypoxic mesenchymal stem cell-derived exosomes promote bone fracture healing by the transfer of miR-126. Acta Biomater 103:196\u2013212","journal-title":"Acta Biomater"},{"key":"4157_CR87","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1186\/s12943-021-01440-5","volume":"21","author":"G He","year":"2022","unstructured":"He G, Peng X, Wei S, Yang S, Li X, Huang M, Tang S, Jin H, Liu J, Zhang S, Zheng H, Fan Q, Liu J, Yang L, Li H (2022) Exosomes in the hypoxic TME: from release, uptake and biofunctions to clinical applications. Mol Cancer 21:19","journal-title":"Mol Cancer"},{"key":"4157_CR88","doi-asserted-by":"publisher","first-page":"3806","DOI":"10.1038\/s41388-018-0189-0","volume":"37","author":"KDP Dorayappan","year":"2018","unstructured":"Dorayappan KDP, Wanner R, Wallbillich JJ, Saini U, Zingarelli R, Suarez AA, Cohn DE, Selvendiran K (2018) Hypoxia-induced exosomes contribute to a more aggressive and chemoresistant ovarian cancer phenotype: a novel mechanism linking STAT3\/Rab proteins. Oncogene 37:3806\u20133821","journal-title":"Oncogene"},{"key":"4157_CR89","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1080\/15384047.2017.1394544","volume":"19","author":"FM Khan","year":"2018","unstructured":"Khan FM, Saleh E, Alawadhi H, Harati R, Zimmermann WH, El-Awady R (2018) Inhibition of exosome release by ketotifen enhances sensitivity of cancer cells to doxorubicin. Cancer Biol Ther 19:25\u201333","journal-title":"Cancer Biol Ther"},{"key":"4157_CR90","doi-asserted-by":"publisher","first-page":"15843","DOI":"10.1074\/jbc.M112.427187","volume":"288","author":"D Bi","year":"2013","unstructured":"Bi D, Toyama K, Lema\u00eetre V, Takai J, Fan F, Jenkins DP, Wulff H, Gutterman DD, Park F, Miura H (2013) The intermediate conductance calcium-activated potassium channel KCa3.1 regulates vascular smooth muscle cell proliferation via controlling calcium-dependent signaling. J Biol Chem 288:15843\u201315853","journal-title":"J Biol Chem"},{"key":"4157_CR91","doi-asserted-by":"crossref","unstructured":"Liu D, Chen H, Fu Y, Yao Y, He S, Wang Y, Cao Z, Wang X, Yang M, Zhao Q (2023) KCa3.1 promotes proinflammatory exosome secretion by activating AKT\/Rab27a in atrial myocytes during rapid pacing. Cardiovasc Ther 2023:3939360","DOI":"10.1155\/2023\/3939360"},{"key":"4157_CR92","doi-asserted-by":"crossref","unstructured":"Krylova SV, Feng D (2023) The machinery of exosomes: biogenesis, release, and uptake. Int J Mol Sci 24","DOI":"10.3390\/ijms24021337"},{"key":"4157_CR93","doi-asserted-by":"publisher","first-page":"1487","DOI":"10.1002\/jcp.24304","volume":"228","author":"T Tian","year":"2013","unstructured":"Tian T, Zhu YL, Hu FH, Wang YY, Huang NP, Xiao ZD (2013) Dynamics of exosome internalization and trafficking. J Cell Physiol 228:1487\u20131495","journal-title":"J Cell Physiol"},{"key":"4157_CR94","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1186\/s13045-016-0269-y","volume":"9","author":"X Li","year":"2016","unstructured":"Li X, Wang S, Zhu R, Li H, Han Q, Zhao RC (2016) Lung tumor exosomes induce a pro-inflammatory phenotype in mesenchymal stem cells via NF\u03baB-TLR signaling pathway. J Hematol Oncol 9:42","journal-title":"J Hematol Oncol"},{"key":"4157_CR95","doi-asserted-by":"crossref","unstructured":"Hamzah RN, Alghazali KM, Biris AS, Griffin RJ (2021) Exosome traceability and cell source dependence on composition and cell-cell cross talk. Int J Mol Sci 22","DOI":"10.3390\/ijms22105346"},{"key":"4157_CR96","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1186\/s12964-021-00730-1","volume":"19","author":"S Gurung","year":"2021","unstructured":"Gurung S, Perocheau D, Touramanidou L, Baruteau J (2021) The exosome journey: from biogenesis to uptake and intracellular signalling. Cell Commun Signal 19:47","journal-title":"Cell Commun Signal"},{"key":"4157_CR97","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1083\/jcb.201403041","volume":"205","author":"A Grassart","year":"2014","unstructured":"Grassart A, Cheng AT, Hong SH, Zhang F, Zenzer N, Feng Y, Briner DM, Davis GD, Malkov D, Drubin DG (2014) Actin and dynamin2 dynamics and interplay during clathrin-mediated endocytosis. J Cell Biol 205:721\u2013735","journal-title":"J Cell Biol"},{"key":"4157_CR98","doi-asserted-by":"publisher","first-page":"10334","DOI":"10.1128\/JVI.01310-13","volume":"87","author":"A Nanbo","year":"2013","unstructured":"Nanbo A, Kawanishi E, Yoshida R, Yoshiyama H (2013) Exosomes derived from Epstein-Barr virus-infected cells are internalized via caveola-dependent endocytosis and promote phenotypic modulation in target cells. J Virol 87:10334\u201310347","journal-title":"J Virol"},{"key":"4157_CR99","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1186\/s12885-017-3958-1","volume":"18","author":"S Horibe","year":"2018","unstructured":"Horibe S, Tanahashi T, Kawauchi S, Murakami Y, Rikitake Y (2018) Mechanism of recipient cell-dependent differences in exosome uptake. BMC Cancer 18:47","journal-title":"BMC Cancer"},{"key":"4157_CR100","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1016\/j.jconrel.2017.09.019","volume":"266","author":"H Costa Verdera","year":"2017","unstructured":"Costa Verdera H, Gitz-Francois JJ, Schiffelers RM, Vader P (2017) Cellular uptake of extracellular vesicles is mediated by clathrin-independent endocytosis and macropinocytosis. J Control Release 266:100\u2013108","journal-title":"J Control Release"},{"key":"4157_CR101","doi-asserted-by":"publisher","first-page":"e2000269","DOI":"10.1002\/mabi.202000269","volume":"21","author":"C Gutierrez-Millan","year":"2021","unstructured":"Gutierrez-Millan C, Calvo D\u00edaz C, Lanao JM, Colino CI (2021) Advances in Exosomes-based drug Delivery systems. Macromol Biosci 21:e2000269","journal-title":"Macromol Biosci"},{"key":"4157_CR102","doi-asserted-by":"publisher","first-page":"751079","DOI":"10.3389\/fcell.2021.751079","volume":"9","author":"H Chen","year":"2021","unstructured":"Chen H, Wang L, Zeng X, Schwarz H, Nanda HS, Peng X, Zhou Y (2021) Exosomes, a New Star for targeted delivery. Front Cell Dev Biol 9:751079","journal-title":"Front Cell Dev Biol"},{"key":"4157_CR103","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1186\/s12964-022-00959-4","volume":"20","author":"J Rezaie","year":"2022","unstructured":"Rezaie J, Feghhi M, Etemadi T (2022) A review on exosomes application in clinical trials: perspective, questions, and challenges. Cell Communication Signal 20:145","journal-title":"Cell Communication Signal"},{"key":"4157_CR104","doi-asserted-by":"crossref","unstructured":"Liu Q, Li S, Dupuy A, Mai HL, Sailliet N, Log\u00e9 C, Robert JH, Brouard S (2021) Exosomes as new biomarkers and drug delivery tools for the Prevention and Treatment of various diseases: current perspectives. Int J Mol Sci 22","DOI":"10.3390\/ijms22157763"},{"key":"4157_CR105","doi-asserted-by":"publisher","first-page":"293","DOI":"10.31083\/j.fbl2710293","volume":"27","author":"Y Zhang","year":"2022","unstructured":"Zhang Y, Li J, Gao W, Xie N (2022) Exosomes as Anticancer Drug Delivery vehicles: prospects and challenges. Front Biosci (Landmark Ed) 27:293","journal-title":"Front Biosci (Landmark Ed)"},{"key":"4157_CR106","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1007\/s10787-022-01115-7","volume":"31","author":"S Sadeghi","year":"2023","unstructured":"Sadeghi S, Tehrani FR, Tahmasebi S, Shafiee A, Hashemi SM (2023) Exosome engineering in cell therapy and drug delivery. Inflammopharmacology 31:145\u2013169","journal-title":"Inflammopharmacology"},{"key":"4157_CR107","doi-asserted-by":"publisher","first-page":"754","DOI":"10.1038\/aps.2017.12","volume":"38","author":"X Luan","year":"2017","unstructured":"Luan X, Sansanaphongpricha K, Myers I, Chen H, Yuan H, Sun D (2017) Engineering exosomes as refined biological nanoplatforms for drug delivery. Acta Pharmacol Sin 38:754\u2013763","journal-title":"Acta Pharmacol Sin"},{"key":"4157_CR108","doi-asserted-by":"publisher","first-page":"442","DOI":"10.1186\/s13287-021-02528-x","volume":"12","author":"Z Yang","year":"2021","unstructured":"Yang Z, Yang Y, Xu Y, Jiang W, Shao Y, Xing J, Chen Y, Han Y (2021) Biomimetic nerve guidance conduit containing engineered exosomes of adipose-derived stem cells promotes peripheral nerve regeneration. Stem Cell Res Ther 12:442","journal-title":"Stem Cell Res Ther"},{"key":"4157_CR109","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1179\/1743132813Y.0000000176","volume":"35","author":"H Jalali","year":"2013","unstructured":"Jalali H, Parivar K, Nabiuni M, Soleimani M (2013) Unrestricted somatic stem cells as vehicle for nerve growth factor gene transfer. Neurol Res 35:553\u2013560","journal-title":"Neurol Res"},{"key":"4157_CR110","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1016\/j.omtn.2020.06.013","volume":"21","author":"J Yang","year":"2020","unstructured":"Yang J, Wu S, Hou L, Zhu D, Yin S, Yang G, Wang Y (2020) Therapeutic effects of simultaneous delivery of nerve growth factor mRNA and protein via Exosomes on cerebral ischemia. Mol Ther Nucleic Acids 21:512\u2013522","journal-title":"Mol Ther Nucleic Acids"},{"key":"4157_CR111","doi-asserted-by":"publisher","first-page":"79","DOI":"10.4103\/0300-1652.110033","volume":"54","author":"IH Abdulkareem","year":"2013","unstructured":"Abdulkareem IH, Blair M (2013) Phosphatase and tensin homologue deleted on chromosome 10. Niger Med J 54:79\u201386","journal-title":"Niger Med J"},{"key":"4157_CR112","doi-asserted-by":"publisher","first-page":"9306","DOI":"10.1523\/JNEUROSCI.6271-09.2010","volume":"30","author":"KJ Christie","year":"2010","unstructured":"Christie KJ, Webber CA, Martinez JA, Singh B, Zochodne DW (2010) PTEN inhibition to facilitate intrinsic regenerative outgrowth of adult peripheral axons. J Neurosci 30:9306\u20139315","journal-title":"J Neurosci"},{"key":"4157_CR113","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1053\/j.gastro.2022.11.025","volume":"164","author":"TY Jiang","year":"2023","unstructured":"Jiang TY, Shi YY, Cui XW, Pan YF, Lin YK, Feng XF, Ding ZW, Yang C, Tan YX, Dong LW, Wang HY (2023) PTEN Deficiency facilitates Exosome Secretion and Metastasis in Cholangiocarcinoma by Impairing TFEB-mediated Lysosome Biogenesis. Gastroenterology 164:424\u2013438","journal-title":"Gastroenterology"},{"key":"4157_CR114","doi-asserted-by":"publisher","first-page":"10015","DOI":"10.1021\/acsnano.9b01892","volume":"13","author":"S Guo","year":"2019","unstructured":"Guo S, Perets N, Betzer O, Ben-Shaul S, Sheinin A, Michaelevski I, Popovtzer R, Offen D, Levenberg S (2019) Intranasal delivery of mesenchymal stem cell derived exosomes loaded with phosphatase and tensin homolog siRNA repairs complete spinal cord Injury. ACS Nano 13:10015\u201310028","journal-title":"ACS Nano"},{"key":"4157_CR115","doi-asserted-by":"publisher","first-page":"655","DOI":"10.1002\/1873-3468.14274","volume":"596","author":"JP Bischoff","year":"2022","unstructured":"Bischoff JP, Schulz A, Morrison H (2022) The role of exosomes in intercellular and inter-organ communication of the peripheral nervous system. FEBS Lett 596:655\u2013664","journal-title":"FEBS Lett"},{"key":"4157_CR116","doi-asserted-by":"publisher","first-page":"2141","DOI":"10.2174\/1570159X19666210203161559","volume":"19","author":"T Yu","year":"2021","unstructured":"Yu T, Xu Y, Ahmad MA, Javed R, Hagiwara H, Tian X (2021) Exosomes as a Promising Therapeutic Strategy for Peripheral nerve Injury. Curr Neuropharmacol 19:2141\u20132151","journal-title":"Curr Neuropharmacol"},{"key":"4157_CR117","doi-asserted-by":"crossref","unstructured":"Rajput A, Varshney A, Bajaj R, Pokharkar V (2022) Exosomes as New Generation vehicles for Drug Delivery: Biomedical Applications and Future perspectives. Molecules 27","DOI":"10.3390\/molecules27217289"},{"key":"4157_CR118","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1007\/s10571-016-0366-z","volume":"36","author":"ER Abels","year":"2016","unstructured":"Abels ER, Breakefield XO (2016) Introduction to extracellular vesicles: biogenesis, RNA cargo selection, content, release, and uptake. Cell Mol Neurobiol 36:301\u2013312","journal-title":"Cell Mol Neurobiol"},{"key":"4157_CR119","doi-asserted-by":"publisher","first-page":"551","DOI":"10.4103\/neuroindia.NI_987_16","volume":"65","author":"JA Kouyoumdjian","year":"2017","unstructured":"Kouyoumdjian JA, Gra\u00e7a CR, Ferreira VFM (2017) Peripheral nerve injuries: a retrospective survey of 1124 cases. Neurol India 65:551\u2013555","journal-title":"Neurol India"},{"key":"4157_CR120","doi-asserted-by":"publisher","first-page":"1419","DOI":"10.4103\/0028-3886.273626","volume":"67","author":"N Kamble","year":"2019","unstructured":"Kamble N, Shukla D, Bhat D (2019) Peripheral nerve injuries: Electrophysiology for the neurosurgeon. Neurol India 67:1419\u20131422","journal-title":"Neurol India"},{"key":"4157_CR121","unstructured":"Biso G, Munakomi S (2023) Neuroanatomy, Neurapraxia. StatPearls. StatPearls Publishing Copyright \u00a9 2023. StatPearls Publishing LLC., Treasure Island (FL)"},{"key":"4157_CR122","doi-asserted-by":"publisher","first-page":"380","DOI":"10.5152\/dir.2019.18296","volume":"25","author":"F Kuo","year":"2019","unstructured":"Kuo F, Park J, Chow K, Chen A, Walsworth MK (2019) Avoiding peripheral nerve injury in arterial interventions. Diagn Interv Radiol 25:380\u2013391","journal-title":"Diagn Interv Radiol"},{"key":"4157_CR123","unstructured":"Chaney B, Nadi M (2023) Axonotmesis. StatPearls. StatPearls Publishing Copyright \u00a9 2023. StatPearls Publishing LLC., Treasure Island (FL)"},{"key":"4157_CR124","unstructured":"Matos Cruz AJ, De Jesus O (2023) Neurotmesis. StatPearls. StatPearls Publishing Copyright \u00a9 2023. StatPearls Publishing LLC., Treasure Island (FL)"},{"key":"4157_CR125","doi-asserted-by":"publisher","first-page":"e0208985","DOI":"10.1371\/journal.pone.0208985","volume":"13","author":"T Wang","year":"2018","unstructured":"Wang T, Ito A, Aoyama T, Nakahara R, Nakahata A, Ji X, Zhang J, Kawai H, Kuroki H (2018) Functional evaluation outcomes correlate with histomorphometric changes in the rat sciatic nerve crush injury model: a comparison between sciatic functional index and kinematic analysis. PLoS ONE 13:e0208985","journal-title":"PLoS ONE"},{"key":"4157_CR126","doi-asserted-by":"publisher","first-page":"1264","DOI":"10.1089\/ten.tea.2011.0491","volume":"18","author":"S Marconi","year":"2012","unstructured":"Marconi S, Castiglione G, Turano E, Bissolotti G, Angiari S, Farinazzo A, Constantin G, Bedogni G, Bedogni A, Bonetti B (2012) Human adipose-derived mesenchymal stem cells systemically injected promote peripheral nerve regeneration in the mouse model of sciatic crush. Tissue Eng Part A 18:1264\u20131272","journal-title":"Tissue Eng Part A"},{"key":"4157_CR127","doi-asserted-by":"publisher","first-page":"4649","DOI":"10.1016\/j.biomaterials.2009.05.037","volume":"30","author":"W Sun","year":"2009","unstructured":"Sun W, Sun C, Lin H, Zhao H, Wang J, Ma H, Chen B, Xiao Z, Dai J (2009) The effect of collagen-binding NGF-beta on the promotion of sciatic nerve regeneration in a rat sciatic nerve crush injury model. Biomaterials 30:4649\u20134656","journal-title":"Biomaterials"},{"key":"4157_CR128","doi-asserted-by":"crossref","unstructured":"Liu YP, Yang YD, Mou FF, Zhu J, Li H, Zhao TT, Zhao Y, Shao SJ, Cui GH, Guo HD (2022) Exosome-mediated miR-21 was involved in the promotion of structural and functional recovery effect produced by electroacupuncture in sciatic nerve injury. Oxid Med Cell Longev 2022:7530102","DOI":"10.1155\/2022\/7530102"},{"key":"4157_CR129","doi-asserted-by":"crossref","unstructured":"Chen W, Xiao S, Wei Z, Deng C, Nie K, Wang D (2019) Schwann Cell-Like Cells Derived from Human Amniotic Mesenchymal Stem Cells Promote Peripheral Nerve Regeneration through a MicroRNA-214\/c-Jun Pathway. Stem Cells Int 2019:2490761","DOI":"10.1155\/2019\/2490761"},{"key":"4157_CR130","doi-asserted-by":"publisher","first-page":"1146329","DOI":"10.3389\/fnmol.2023.1146329","volume":"16","author":"X Zeng","year":"2023","unstructured":"Zeng X, Bian W, Liu Z, Li J, Ren S, Zhang J, Zhang H, Tegeleqi B, He G, Guan M, Gao Z, Huang C, Liu J (2023) Muscle-derived stem cell exosomes with overexpressed miR-214 promote the regeneration and repair of rat sciatic nerve after crush injury to activate the JAK2\/STAT3 pathway by targeting PTEN. Front Mol Neurosci 16:1146329","journal-title":"Front Mol Neurosci"},{"key":"4157_CR131","doi-asserted-by":"crossref","unstructured":"Trzyna A, Bana\u015b-Z\u0105bczyk A (2021) Adipose-derived stem cells Secretome and its potential application in Stem Cell-Free Therapy. Biomolecules 11","DOI":"10.3390\/biom11060878"},{"key":"4157_CR132","doi-asserted-by":"publisher","first-page":"1710","DOI":"10.1159\/000492298","volume":"48","author":"J Ni","year":"2018","unstructured":"Ni J, Li H, Zhou Y, Gu B, Xu Y, Fu Q, Peng X, Cao N, Fu Q, Jin M, Sun G, Wang J, Jin Y, Liu F (2018) Therapeutic potential of human adipose-derived stem cell exosomes in stress urinary incontinence - an in Vitro and in vivo study. Cell Physiol Biochem 48:1710\u20131722","journal-title":"Cell Physiol Biochem"},{"key":"4157_CR133","doi-asserted-by":"publisher","first-page":"1812","DOI":"10.1007\/s12035-018-1172-z","volume":"56","author":"V Bucan","year":"2019","unstructured":"Bucan V, Vaslaitis D, Peck CT, Strau\u00df S, Vogt PM, Radtke C (2019) Effect of Exosomes from Rat adipose-derived mesenchymal stem cells on Neurite Outgrowth and sciatic nerve regeneration after crush Injury. Mol Neurobiol 56:1812\u20131824","journal-title":"Mol Neurobiol"},{"key":"4157_CR134","doi-asserted-by":"publisher","first-page":"e20210564","DOI":"10.1590\/0001-3765202220210564","volume":"94","author":"YU Zhang","year":"2022","unstructured":"Zhang YU, Ye G, Zhao J, Chen Y, Kong L, Sheng C, Yuan L (2022) Exosomes carried miR-181c-5p alleviates neuropathic pain in CCI rat models. Acad Bras Cienc 94:e20210564","journal-title":"Acad Bras Cienc"},{"key":"4157_CR135","doi-asserted-by":"crossref","unstructured":"Massoumi H, Amin S, Soleimani M, Momenaei B, Ashraf MJ, Guaiquil VH, Hematti P, Rosenblatt MI, Djalilian AR, Jalilian E (2023) Extracellular-vesicle-based therapeutics in Neuro-Ophthalmic disorders. Int J Mol Sci 24","DOI":"10.3390\/ijms24109006"},{"key":"4157_CR136","doi-asserted-by":"publisher","first-page":"10519","DOI":"10.2147\/IJN.S277190","volume":"15","author":"J Liu","year":"2020","unstructured":"Liu J, Jiang F, Jiang Y, Wang Y, Li Z, Shi X, Zhu Y, Wang H, Zhang Z (2020) Roles of exosomes in Ocular diseases. Int J Nanomed 15:10519\u201310538","journal-title":"Int J Nanomed"},{"key":"4157_CR137","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/j.exer.2015.01.019","volume":"132","author":"WM Dismuke","year":"2015","unstructured":"Dismuke WM, Challa P, Navarro I, Stamer WD, Liu Y (2015) Human aqueous humor exosomes. Exp Eye Res 132:73\u201377","journal-title":"Exp Eye Res"},{"key":"4157_CR138","first-page":"671","volume":"43","author":"H Wang","year":"2019","unstructured":"Wang H, Li M, Zhang Z, Xue H, Chen X, Ji Y (2019) Physiological function of myocilin and its role in the pathogenesis of glaucoma in the trabecular meshwork (review). Int J Mol Med 43:671\u2013681","journal-title":"Int J Mol Med"},{"key":"4157_CR139","doi-asserted-by":"publisher","first-page":"129","DOI":"10.3233\/TUB-211543","volume":"44","author":"R Manukonda","year":"2022","unstructured":"Manukonda R, Attem J, Yenuganti VR, Kaliki S, Vemuganti GK (2022) Exosomes in the visual system: new avenues in ocular diseases. Tumour Biol 44:129\u2013152","journal-title":"Tumour Biol"},{"key":"4157_CR140","doi-asserted-by":"publisher","first-page":"1313","DOI":"10.1167\/iovs.08-2326","volume":"50","author":"EA Hoffman","year":"2009","unstructured":"Hoffman EA, Perkumas KM, Highstrom LM, Stamer WD (2009) Regulation of myocilin-associated exosome release from human trabecular meshwork cells. Invest Ophthalmol Vis Sci 50:1313\u20131318","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"4157_CR141","doi-asserted-by":"publisher","first-page":"28917","DOI":"10.1074\/jbc.M504803200","volume":"280","author":"KM Hardy","year":"2005","unstructured":"Hardy KM, Hoffman EA, Gonzalez P, McKay BS, Stamer WD (2005) Extracellular trafficking of Myocilin in human trabecular meshwork Cells*. J Biol Chem 280:28917\u201328926","journal-title":"J Biol Chem"},{"key":"4157_CR142","doi-asserted-by":"publisher","first-page":"796","DOI":"10.1016\/j.jprot.2011.02.024","volume":"74","author":"WD Stamer","year":"2011","unstructured":"Stamer WD, Hoffman EA, Luther JM, Hachey DL, Schey KL (2011) Protein profile of exosomes from trabecular meshwork cells. J Proteom 74:796\u2013804","journal-title":"J Proteom"},{"key":"4157_CR143","doi-asserted-by":"publisher","first-page":"4528","DOI":"10.1167\/iovs.16-19688","volume":"57","author":"Y Liu","year":"2016","unstructured":"Liu Y, Bailey JC, Helwa I, Dismuke WM, Cai J, Drewry M, Brilliant MH, Budenz DL, Christen WG, Chasman DI, Fingert JH, Gaasterland D, Gaasterland T, Gordon MO, Igo RP Jr., Kang JH, Kass MA, Kraft P, Lee RK, Lichter P, Moroi SE, Realini A, Richards JE, Ritch R, Schuman JS, Scott WK, Singh K, Sit AJ, Song YE, Vollrath D, Weinreb R, Medeiros F, Wollstein G, Zack DJ, Zhang K, Pericak-Vance MA, Gonzalez P, Stamer WD, Kuchtey J, Kuchtey RW, Allingham RR, Hauser MA, Pasquale LR, Haines JL, Wiggs JL (2016) A common variant in MIR182 is Associated with Primary Open-Angle Glaucoma in the NEIGHBORHOOD Consortium. Invest Ophthalmol Vis Sci 57:4528\u20134535","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"4157_CR144","doi-asserted-by":"crossref","unstructured":"Pattabiraman PP, Feinstein V, Beit-Yannai E (2023) Profiling the miRNA from Exosomes of Non-pigmented Ciliary Epithelium-Derived identifies key gene targets relevant to primary Open-Angle Glaucoma. Antioxidants (Basel) 12","DOI":"10.3390\/antiox12020405"},{"key":"4157_CR145","doi-asserted-by":"crossref","unstructured":"Vomund S, Sch\u00e4fer A, Parnham MJ, Br\u00fcne B, von Knethen A (2017) Nrf2, the Master Regulator of anti-oxidative responses. Int J Mol Sci 18","DOI":"10.3390\/ijms18122772"},{"key":"4157_CR146","doi-asserted-by":"publisher","first-page":"4646","DOI":"10.1111\/jcmm.15129","volume":"24","author":"N Lerner","year":"2020","unstructured":"Lerner N, Schreiber-Avissar S, Beit-Yannai E (2020) Extracellular vesicle-mediated crosstalk between NPCE cells and TM cells result in modulation of wnt signalling pathway and ECM remodelling. J Cell Mol Med 24:4646\u20134658","journal-title":"J Cell Mol Med"},{"key":"4157_CR147","doi-asserted-by":"crossref","unstructured":"Tabak S, Feinshtein V, Schreiber-Avissar S, Beit-Yannai E (2021) Non-pigmented ciliary epithelium-derived extracellular vesicles loaded with SMAD7 siRNA attenuate wnt signaling in trabecular meshwork cells in Vitro. Pharmaceuticals (Basel) 14","DOI":"10.3390\/ph14090858"},{"key":"4157_CR148","doi-asserted-by":"publisher","first-page":"1273","DOI":"10.1002\/sctm.16-0428","volume":"6","author":"B Mead","year":"2017","unstructured":"Mead B, Tomarev S (2017) Bone marrow-derived mesenchymal stem cells-derived exosomes promote survival of retinal ganglion cells through miRNA-Dependent mechanisms. Stem Cells Transl Med 6:1273\u20131285","journal-title":"Stem Cells Transl Med"},{"key":"4157_CR149","doi-asserted-by":"publisher","first-page":"360","DOI":"10.3389\/fcell.2019.00360","volume":"7","author":"M M\u00fcller","year":"2019","unstructured":"M\u00fcller M, Fazi F, Ciaudo C (2019) Argonaute proteins: from structure to function in Development and pathological cell fate determination. Front Cell Dev Biol 7:360","journal-title":"Front Cell Dev Biol"},{"key":"4157_CR150","doi-asserted-by":"publisher","first-page":"702","DOI":"10.1167\/iovs.17-22855","volume":"59","author":"B Mead","year":"2018","unstructured":"Mead B, Amaral J, Tomarev S (2018) Mesenchymal stem cell-derived small extracellular vesicles promote Neuroprotection in Rodent models of Glaucoma. Invest Ophthalmol Vis Sci 59:702\u2013714","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"4157_CR151","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1016\/j.jchemneu.2019.01.006","volume":"96","author":"D Pan","year":"2019","unstructured":"Pan D, Chang X, Xu M, Zhang M, Zhang S, Wang Y, Luo X, Xu J, Yang X, Sun X (2019) UMSC-derived exosomes promote retinal ganglion cells survival in a rat model of optic nerve crush. J Chem Neuroanat 96:134\u2013139","journal-title":"J Chem Neuroanat"},{"key":"4157_CR152","doi-asserted-by":"publisher","first-page":"14863","DOI":"10.1038\/s41598-021-94365-4","volume":"11","author":"YC Li","year":"2021","unstructured":"Li YC, Zheng J, Wang XZ, Wang X, Liu WJ, Gao JL (2021) Mesenchymal stem cell-derived exosomes protect trabecular meshwork from oxidative stress. Sci Rep 11:14863","journal-title":"Sci Rep"},{"key":"4157_CR153","doi-asserted-by":"publisher","first-page":"630808","DOI":"10.3389\/fnmol.2021.630808","volume":"14","author":"M Guo","year":"2021","unstructured":"Guo M, Hao Y, Feng Y, Li H, Mao Y, Dong Q, Cui M (2021) Microglial exosomes in neurodegenerative disease. Front Mol Neurosci 14:630808","journal-title":"Front Mol Neurosci"},{"key":"4157_CR154","doi-asserted-by":"publisher","first-page":"601","DOI":"10.3389\/fnins.2019.00601","volume":"13","author":"F Gentile","year":"2019","unstructured":"Gentile F, Scarlino S, Falzone YM, Lunetta C, Tremolizzo L, Quattrini A, Riva N (2019) The Peripheral Nervous System in Amyotrophic lateral sclerosis: opportunities for Translational Research. Front Neurosci 13:601","journal-title":"Front Neurosci"},{"key":"4157_CR155","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1016\/S1474-4422(08)70293-X","volume":"8","author":"MR Turner","year":"2009","unstructured":"Turner MR, Kiernan MC, Leigh PN, Talbot K (2009) Biomarkers in amyotrophic lateral sclerosis. Lancet Neurol 8:94\u2013109","journal-title":"Lancet Neurol"},{"key":"4157_CR156","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1186\/s40035-015-0040-2","volume":"4","author":"X Chen","year":"2015","unstructured":"Chen X, Shang HF (2015) New developments and future opportunities in biomarkers for amyotrophic lateral sclerosis. Transl Neurodegener 4:17","journal-title":"Transl Neurodegener"},{"key":"4157_CR157","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1007\/s00018-020-03619-3","volume":"78","author":"D Gagliardi","year":"2021","unstructured":"Gagliardi D, Bresolin N, Comi GP, Corti S (2021) Extracellular vesicles and amyotrophic lateral sclerosis: from misfolded protein vehicles to promising clinical biomarkers. Cell Mol Life Sci 78:561\u2013572","journal-title":"Cell Mol Life Sci"},{"key":"4157_CR158","doi-asserted-by":"crossref","unstructured":"Gagliardi D, Meneri M, Saccomanno D, Bresolin N, Comi GP, Corti S (2019) Diagnostic and prognostic role of blood and cerebrospinal fluid and blood neurofilaments in amyotrophic lateral sclerosis: a review of the literature. Int J Mol Sci 20","DOI":"10.3390\/ijms20174152"},{"key":"4157_CR159","doi-asserted-by":"publisher","first-page":"1119","DOI":"10.1007\/s13311-022-01232-9","volume":"19","author":"G Kim","year":"2022","unstructured":"Kim G, Chen X, Yang Y (2022) Pathogenic extracellular vesicle (EV) signaling in amyotrophic lateral sclerosis (ALS). Neurotherapeutics 19:1119\u20131132","journal-title":"Neurotherapeutics"},{"key":"4157_CR160","doi-asserted-by":"publisher","first-page":"432","DOI":"10.1186\/s12967-020-02609-0","volume":"18","author":"K Xu","year":"2020","unstructured":"Xu K, Liu Q, Wu K, Liu L, Zhao M, Yang H, Wang X, Wang W (2020) Extracellular vesicles as potential biomarkers and therapeutic approaches in autoimmune diseases. J Transl Med 18:432","journal-title":"J Transl Med"},{"key":"4157_CR161","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1186\/s12920-019-0473-z","volume":"12","author":"K Otake","year":"2019","unstructured":"Otake K, Kamiguchi H, Hirozane Y (2019) Identification of biomarkers for amyotrophic lateral sclerosis by comprehensive analysis of exosomal mRNAs in human cerebrospinal fluid. BMC Med Genomics 12:7","journal-title":"BMC Med Genomics"},{"key":"4157_CR162","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1136\/jnnp-2021-327133","volume":"93","author":"AG Thompson","year":"2022","unstructured":"Thompson AG, Talbot K, Turner MR (2022) Higher blood high density lipoprotein and apolipoprotein A1 levels are associated with reduced risk of developing amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry 93:75\u201381","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"4157_CR163","doi-asserted-by":"crossref","unstructured":"McCluskey G, Donaghy C, Morrison KE, McConville J, Duddy W, Duguez S (2022) The role of Sphingomyelin and Ceramide in Motor Neuron diseases. J Pers Med 12","DOI":"10.3390\/jpm12091418"},{"key":"4157_CR164","doi-asserted-by":"publisher","first-page":"4425","DOI":"10.1093\/brain\/awac025","volume":"145","author":"SA Goutman","year":"2022","unstructured":"Goutman SA, Guo K, Savelieff MG, Patterson A, Sakowski SA, Habra H, Karnovsky A, Hur J, Feldman EL (2022) Metabolomics identifies shared lipid pathways in independent amyotrophic lateral sclerosis cohorts. Brain 145:4425\u20134439","journal-title":"Brain"},{"key":"4157_CR165","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1007\/s10571-015-0294-3","volume":"36","author":"JM Silverman","year":"2016","unstructured":"Silverman JM, Fernando SM, Grad LI, Hill AF, Turner BJ, Yerbury JJ, Cashman NR (2016) Disease mechanisms in ALS: misfolded SOD1 transferred through exosome-dependent and exosome-independent pathways. Cell Mol Neurobiol 36:377\u2013381","journal-title":"Cell Mol Neurobiol"},{"key":"4157_CR166","doi-asserted-by":"publisher","first-page":"604171","DOI":"10.3389\/fncel.2020.604171","volume":"14","author":"BW Kim","year":"2020","unstructured":"Kim BW, Ryu J, Jeong YE, Kim J, Martin LJ (2020) Human motor neurons with SOD1-G93A mutation generated from CRISPR\/Cas9 gene-edited iPSCs develop pathological features of amyotrophic lateral sclerosis. Front Cell Neurosci 14:604171","journal-title":"Front Cell Neurosci"},{"key":"4157_CR167","doi-asserted-by":"publisher","first-page":"80","DOI":"10.3389\/fncel.2017.00080","volume":"11","author":"R Bonafede","year":"2017","unstructured":"Bonafede R, Mariotti R (2017) ALS Pathogenesis and Therapeutic approaches: the role of mesenchymal stem cells and extracellular vesicles. Front Cell Neurosci 11:80","journal-title":"Front Cell Neurosci"},{"key":"4157_CR168","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1016\/j.yexcr.2015.12.009","volume":"340","author":"R Bonafede","year":"2016","unstructured":"Bonafede R, Scambi I, Peroni D, Potrich V, Boschi F, Benati D, Bonetti B, Mariotti R (2016) Exosome derived from murine adipose-derived stromal cells: neuroprotective effect on in vitro model of amyotrophic lateral sclerosis. Exp Cell Res 340:150\u2013158","journal-title":"Exp Cell Res"},{"key":"4157_CR169","doi-asserted-by":"publisher","first-page":"1740","DOI":"10.1038\/s41598-021-81039-4","volume":"11","author":"D Giunti","year":"2021","unstructured":"Giunti D, Marini C, Parodi B, Usai C, Milanese M, Bonanno G, Kerlero de Rosbo N, Uccelli A (2021) Role of miRNAs shuttled by mesenchymal stem cell-derived small extracellular vesicles in modulating neuroinflammation. Sci Rep 11:1740","journal-title":"Sci Rep"},{"key":"4157_CR170","doi-asserted-by":"publisher","first-page":"2142","DOI":"10.1021\/acs.molpharmaceut.1c00297","volume":"18","author":"GR Ediriweera","year":"2021","unstructured":"Ediriweera GR, Chen L, Yerbury JJ, Thurecht KJ, Vine KL (2021) Non-viral vector-mediated gene therapy for ALS: challenges and Future perspectives. Mol Pharm 18:2142\u20132160","journal-title":"Mol Pharm"},{"key":"4157_CR171","doi-asserted-by":"publisher","first-page":"754630","DOI":"10.3389\/fcell.2021.754630","volume":"9","author":"K Wang","year":"2021","unstructured":"Wang K, Li Y, Ren C, Wang Y, He W, Jiang Y (2021) Extracellular vesicles as innovative treatment strategy for amyotrophic lateral sclerosis. Front Cell Dev Biol 9:754630","journal-title":"Front Cell Dev Biol"},{"key":"4157_CR172","doi-asserted-by":"crossref","unstructured":"Zhu Y, Han S, Li X, Gao Y, Zhu J, Yang X, Xu L (2021) Paeoniflorin Effect of Schwann Cell-Derived Exosomes Ameliorates Dorsal Root Ganglion Neurons Apoptosis through IRE1\u03b1 Pathway. Evid Based Complement Alternat Med 2021:6079305","DOI":"10.1155\/2021\/6079305"},{"key":"4157_CR173","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1016\/j.cyto.2018.10.007","volume":"113","author":"P Yan","year":"2019","unstructured":"Yan P, Xu Y, Zhang Z, Gao C, Zhu J, Li H, Wan Q (2019) Decreased plasma neuregulin 4 levels are associated with peripheral neuropathy in Chinese patients with newly diagnosed type 2 diabetes: a cross-sectional study. Cytokine 113:356\u2013364","journal-title":"Cytokine"},{"key":"4157_CR174","doi-asserted-by":"publisher","first-page":"340","DOI":"10.2337\/diacare.29.02.06.dc05-1549","volume":"29","author":"CL Martin","year":"2006","unstructured":"Martin CL, Albers J, Herman WH, Cleary P, Waberski B, Greene DA, Stevens MJ, Feldman EL (2006) Neuropathy among the diabetes control and complications trial cohort 8 years after trial completion. Diabetes Care 29:340\u2013344","journal-title":"Diabetes Care"},{"key":"4157_CR175","doi-asserted-by":"crossref","unstructured":"Fujita Y, Murakami T, Nakamura A (2021) Recent advances in biomarkers and Regenerative Medicine for Diabetic Neuropathy. Int J Mol Sci 22","DOI":"10.3390\/ijms22052301"},{"key":"4157_CR176","first-page":"2231","volume":"6","author":"A Singh","year":"2021","unstructured":"Singh A, Raghav A, Shiekh PA, Kumar A (2021) Transplantation of engineered exosomes derived from bone marrow mesenchymal stromal cells ameliorate diabetic peripheral neuropathy under electrical stimulation. Bioact Mater 6:2231\u20132249","journal-title":"Bioact Mater"},{"key":"4157_CR177","doi-asserted-by":"publisher","first-page":"e0131144","DOI":"10.1371\/journal.pone.0131144","volume":"10","author":"S Kambiz","year":"2015","unstructured":"Kambiz S, van Neck JW, Cosgun SG, van Velzen MH, Janssen JA, Avazverdi N, Hovius SE, Walbeehm ET (2015) Correction: an early Diagnostic Tool for Diabetic Peripheral Neuropathy in rats. PLoS ONE 10:e0131144","journal-title":"PLoS ONE"},{"key":"4157_CR178","doi-asserted-by":"publisher","first-page":"117459","DOI":"10.1016\/j.lfs.2020.117459","volume":"248","author":"Y-p Liu","year":"2020","unstructured":"Liu Y-p, Shao S-j, Guo H-d (2020) Schwann cells apoptosis is induced by high glucose in diabetic peripheral neuropathy. Life Sci 248:117459","journal-title":"Life Sci"},{"key":"4157_CR179","doi-asserted-by":"publisher","first-page":"928","DOI":"10.1111\/1753-0407.12916","volume":"11","author":"H Pan","year":"2019","unstructured":"Pan H, Huang H, Zhang L, Ma S, Yang H, Wang H (2019) Adjusting internal organs and dredging channel electroacupuncture treatment prevents the development of diabetic peripheral neuropathy by downregulating glucose-related protein 78 (GRP78) and caspase-12 in streptozotocin-diabetic rats. J Diabetes 11:928\u2013937","journal-title":"J Diabetes"},{"key":"4157_CR180","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1089\/ars.2008.2235","volume":"11","author":"AM Vincent","year":"2009","unstructured":"Vincent AM, Kato K, McLean LL, Soules ME, Feldman EL (2009) Sensory neurons and schwann cells respond to oxidative stress by increasing antioxidant defense mechanisms. Antioxid Redox Signal 11:425\u2013438","journal-title":"Antioxid Redox Signal"},{"key":"4157_CR181","doi-asserted-by":"publisher","first-page":"7841","DOI":"10.12659\/MSM.909509","volume":"24","author":"M Zhou","year":"2018","unstructured":"Zhou M, Hu M, He S, Li B, Liu C, Min J, Hong L (2018) Effects of RSC96 Schwann Cell-Derived exosomes on Proliferation, Senescence, and apoptosis of dorsal Root Ganglion cells in Vitro. Med Sci Monit 24:7841\u20137849","journal-title":"Med Sci Monit"},{"key":"4157_CR182","doi-asserted-by":"publisher","first-page":"3691","DOI":"10.1111\/jog.14968","volume":"47","author":"G Huang","year":"2021","unstructured":"Huang G, Hu M, Lu D, Hong L (2021) Protective effect and potential mechanism of Schwann cell-derived exosomes on mechanical damage of rat dorsal root ganglion cells. J Obstet Gynaecol Res 47:3691\u20133701","journal-title":"J Obstet Gynaecol Res"},{"key":"4157_CR183","doi-asserted-by":"publisher","first-page":"1036","DOI":"10.1038\/ncb2574","volume":"14","author":"JC Gross","year":"2012","unstructured":"Gross JC, Chaudhary V, Bartscherer K, Boutros M (2012) Active wnt proteins are secreted on exosomes. Nat Cell Biol 14:1036\u20131045","journal-title":"Nat Cell Biol"},{"key":"4157_CR184","doi-asserted-by":"publisher","first-page":"113694","DOI":"10.1016\/j.expneurol.2021.113694","volume":"341","author":"B Fan","year":"2021","unstructured":"Fan B, Chopp M, Zhang ZG, Liu XS (2021) Treatment of diabetic peripheral neuropathy with engineered mesenchymal stromal cell-derived exosomes enriched with microRNA-146a provide amplified therapeutic efficacy. Exp Neurol 341:113694","journal-title":"Exp Neurol"},{"key":"4157_CR185","doi-asserted-by":"publisher","first-page":"222","DOI":"10.9758\/cpn.2023.21.2.222","volume":"21","author":"J Finsterer","year":"2023","unstructured":"Finsterer J (2023) Neurological adverse reactions to SARS-CoV-2 vaccines. Clin Psychopharmacol Neurosci 21:222\u2013239","journal-title":"Clin Psychopharmacol Neurosci"},{"key":"4157_CR186","doi-asserted-by":"publisher","first-page":"e0007695","DOI":"10.1371\/journal.pntd.0007695","volume":"13","author":"J Rivera-Correa","year":"2019","unstructured":"Rivera-Correa J, de Siqueira IC, Mota S, do Ros\u00e1rio MS, Pereira de Jesus PA, Alcantara LCJ, Ernst JD, Rodriguez A (2019) Anti-ganglioside antibodies in patients with Zika virus infection-associated Guillain-Barr\u00e9 Syndrome in Brazil. PLoS Negl Trop Dis 13:e0007695","journal-title":"PLoS Negl Trop Dis"},{"key":"4157_CR187","doi-asserted-by":"publisher","first-page":"305","DOI":"10.4103\/0972-2327.74195","volume":"13","author":"NN Baheti","year":"2010","unstructured":"Baheti NN, Manuel D, Shinde PD, Radhakrishnan A, Nair M (2010) Hyperreflexic Guillain-Barr\u00e9 syndrome. Ann Indian Acad Neurol 13:305\u2013307","journal-title":"Ann Indian Acad Neurol"},{"key":"4157_CR188","doi-asserted-by":"publisher","first-page":"1603","DOI":"10.3389\/fimmu.2020.01603","volume":"11","author":"T Du","year":"2020","unstructured":"Du T, Yang CL, Ge MR, Liu Y, Zhang P, Li H, Li XL, Li T, Liu YD, Dou YC, Yang B, Duan RS (2020) M1 macrophage derived exosomes aggravate experimental autoimmune neuritis via modulating Th1 response. Front Immunol 11:1603","journal-title":"Front Immunol"},{"key":"4157_CR189","first-page":"e8052","volume":"12","author":"A Parveen","year":"2020","unstructured":"Parveen A, Khan SA, Talat S, Hussain SNF (2020) Comparison of the clinical outcomes of Guillain Barre Syndrome based on electrophysiological subtypes in Pakistani children. Cureus 12:e8052","journal-title":"Cureus"},{"key":"4157_CR190","doi-asserted-by":"crossref","unstructured":"Hahn AF (1998) Guillain-Barr\u00e9 syndrome. The Lancet 352:635\u2013641","DOI":"10.1016\/S0140-6736(97)12308-X"},{"key":"4157_CR191","doi-asserted-by":"publisher","first-page":"e13024","DOI":"10.1111\/cpr.13024","volume":"54","author":"Z Li","year":"2021","unstructured":"Li Z, Huang Z, Li X, Huang C, Shen J, Li S, Zhang L, Wong SH, Chan MTV, Wu WKK (2021) Bioinformatic analyses hinted at augmented T helper 17 cell differentiation and cytokine response as the central mechanism of COVID-19-associated Guillain-Barr\u00e9 syndrome. Cell Prolif 54:e13024","journal-title":"Cell Prolif"},{"key":"4157_CR192","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1038\/nrneurol.2014.121","volume":"10","author":"B van den Berg","year":"2014","unstructured":"van den Berg B, Walgaard C, Drenthen J, Fokke C, Jacobs BC, van Doorn PA (2014) Guillain-Barr\u00e9 syndrome: pathogenesis, diagnosis, treatment and prognosis. Nat Rev Neurol 10:469\u2013482","journal-title":"Nat Rev Neurol"},{"key":"4157_CR193","doi-asserted-by":"publisher","first-page":"74582","DOI":"10.18632\/oncotarget.12789","volume":"7","author":"L Mateos-Hern\u00e1ndez","year":"2016","unstructured":"Mateos-Hern\u00e1ndez L, Villar M, Doncel-P\u00e9rez E, Trevisan-Herraz M, Garc\u00eda-Forcada \u00c1, Ganuza FR, V\u00e1zquez J, de la Fuente J (2016) Quantitative proteomics reveals Piccolo as a candidate serological correlate of recovery from Guillain-Barr\u00e9 syndrome. Oncotarget 7:74582\u201374591","journal-title":"Oncotarget"},{"key":"4157_CR194","doi-asserted-by":"crossref","unstructured":"Shen D, Chu F, Lang Y, Geng Y, Zheng X, Zhu J, Liu K (2018) Beneficial or Harmful Role of Macrophages in Guillain-Barr\u00e9 Syndrome and Experimental Autoimmune Neuritis. Mediators Inflamm 2018:4286364","DOI":"10.1155\/2018\/4286364"},{"key":"4157_CR195","doi-asserted-by":"publisher","first-page":"111489","DOI":"10.1016\/j.biopha.2021.111489","volume":"138","author":"K Ren","year":"2021","unstructured":"Ren K, Li S, Ding J, Zhao S, Liang S, Cao X, Su C, Guo J (2021) Ginsenoside Rd attenuates mouse experimental autoimmune neuritis by modulating monocyte subsets conversion. Biomed Pharmacother 138:111489","journal-title":"Biomed Pharmacother"},{"key":"4157_CR196","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1186\/s12974-016-0559-x","volume":"13","author":"R Han","year":"2016","unstructured":"Han R, Xiao J, Zhai H, Hao J (2016) Dimethyl fumarate attenuates experimental autoimmune neuritis through the nuclear factor erythroid-derived 2-related factor 2\/hemoxygenase-1 pathway by altering the balance of M1\/M2 macrophages. J Neuroinflamm 13:97","journal-title":"J Neuroinflamm"},{"key":"4157_CR197","doi-asserted-by":"publisher","first-page":"2346","DOI":"10.3389\/fimmu.2019.02346","volume":"10","author":"R Yang","year":"2019","unstructured":"Yang R, Liao Y, Wang L, He P, Hu Y, Yuan D, Wu Z, Sun X (2019) Exosomes Derived from M2b macrophages Attenuate DSS-Induced Colitis. Front Immunol 10:2346","journal-title":"Front Immunol"},{"key":"4157_CR198","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1186\/s40364-022-00374-4","volume":"10","author":"A Hazrati","year":"2022","unstructured":"Hazrati A, Soudi S, Malekpour K, Mahmoudi M, Rahimi A, Hashemi SM, Varma RS (2022) Immune cells-derived exosomes function as a double-edged sword: role in disease progression and their therapeutic applications. Biomark Res 10:30","journal-title":"Biomark Res"},{"key":"4157_CR199","doi-asserted-by":"crossref","unstructured":"Rahimian S, Najafi H, Afzali B, Doroudian M (2024) Extracellular vesicles and exosomes: Novel insights and perspectives on Lung Cancer from early detection to targeted treatment. Biomedicines 12","DOI":"10.3390\/biomedicines12010123"},{"key":"4157_CR200","doi-asserted-by":"publisher","first-page":"011503","DOI":"10.1063\/1.5087122","volume":"3","author":"X Li","year":"2019","unstructured":"Li X, Corbett AL, Taatizadeh E, Tasnim N, Little JP, Garnis C, Daugaard M, Guns E, Hoorfar M, Li ITS (2019) Challenges and opportunities in exosome research-perspectives from biology, engineering, and cancer therapy. APL Bioeng 3:011503","journal-title":"APL Bioeng"},{"key":"4157_CR201","doi-asserted-by":"publisher","first-page":"835","DOI":"10.1248\/bpb.b18-00133","volume":"41","author":"T Yamashita","year":"2018","unstructured":"Yamashita T, Takahashi Y, Takakura Y (2018) Possibility of exosome-based therapeutics and challenges in production of exosomes eligible for therapeutic application. Biol Pharm Bull 41:835\u2013842","journal-title":"Biol Pharm Bull"},{"key":"4157_CR202","doi-asserted-by":"crossref","unstructured":"Zeng H, Guo S, Ren X, Wu Z, Liu S, Yao X (2023) Current Strategies for Exosome Cargo Loading and Targeting Delivery. Cells 12","DOI":"10.3390\/cells12101416"},{"key":"4157_CR203","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/j.jbiotec.2013.03.013","volume":"165","author":"Y Takahashi","year":"2013","unstructured":"Takahashi Y, Nishikawa M, Shinotsuka H, Matsui Y, Ohara S, Imai T, Takakura Y (2013) Visualization and in vivo tracking of the exosomes of murine melanoma B16-BL6 cells in mice after intravenous injection. J Biotechnol 165:77\u201384","journal-title":"J Biotechnol"},{"key":"4157_CR204","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1002\/jps.24251","volume":"104","author":"M Morishita","year":"2015","unstructured":"Morishita M, Takahashi Y, Nishikawa M, Sano K, Kato K, Yamashita T, Imai T, Saji H, Takakura Y (2015) Quantitative analysis of tissue distribution of the B16BL6-derived exosomes using a streptavidin-lactadherin fusion protein and iodine-125-labeled biotin derivative after intravenous injection in mice. J Pharm Sci 104:705\u2013713","journal-title":"J Pharm Sci"},{"key":"4157_CR205","doi-asserted-by":"publisher","first-page":"26316","DOI":"10.3402\/jev.v4.26316","volume":"4","author":"OP Wiklander","year":"2015","unstructured":"Wiklander OP, Nordin JZ, O\u2019Loughlin A, Gustafsson Y, Corso G, M\u00e4ger I, Vader P, Lee Y, Sork H, Seow Y (2015) Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting. J Extracell Vesicles 4:26316","journal-title":"J Extracell Vesicles"},{"key":"4157_CR206","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1016\/j.ejps.2016.10.009","volume":"96","author":"C Charoenviriyakul","year":"2017","unstructured":"Charoenviriyakul C, Takahashi Y, Morishita M, Matsumoto A, Nishikawa M, Takakura Y (2017) Cell type-specific and common characteristics of exosomes derived from mouse cell lines: yield, physicochemical properties, and pharmacokinetics. Eur J Pharm Sci 96:316\u2013322","journal-title":"Eur J Pharm Sci"},{"key":"4157_CR207","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1038\/mt.2012.180","volume":"21","author":"S-i Ohno","year":"2013","unstructured":"Ohno S-i, Takanashi M, Sudo K, Ueda S, Ishikawa A, Matsuyama N, Fujita K, Mizutani T, Ohgi T, Ochiya T (2013) Systemically injected exosomes targeted to EGFR deliver antitumor microRNA to breast cancer cells. Mol Ther 21:185\u2013191","journal-title":"Mol Ther"},{"key":"4157_CR208","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1186\/s13287-023-03467-5","volume":"14","author":"MS Namini","year":"2023","unstructured":"Namini MS, Daneshimehr F, Beheshtizadeh N, Mansouri V, Ai J, Jahromi HK, Ebrahimi-Barough S (2023) Cell-free therapy based on extracellular vesicles: a promising therapeutic strategy for peripheral nerve injury. Stem Cell Res Ther 14:254","journal-title":"Stem Cell Res Ther"},{"key":"4157_CR209","doi-asserted-by":"publisher","first-page":"19","DOI":"10.4252\/wjsc.v16.i1.19","volume":"16","author":"E Civelek","year":"2024","unstructured":"Civelek E, Kabatas S, Savrunlu EC, Diren F, Kaplan N, Ofluo\u011flu D, Kara\u00f6z E (2024) Effects of exosomes from mesenchymal stem cells on functional recovery of a patient with total radial nerve injury: a pilot study. World J Stem Cells 16:19\u201332","journal-title":"World J Stem Cells"},{"key":"4157_CR210","doi-asserted-by":"publisher","first-page":"63","DOI":"10.3389\/fcvm.2017.00063","volume":"4","author":"GR Willis","year":"2017","unstructured":"Willis GR, Kourembanas S, Mitsialis SA (2017) Toward exosome-based therapeutics: isolation, heterogeneity, and fit-for-purpose potency. Front Cardiovasc Med 4:63","journal-title":"Front Cardiovasc Med"},{"key":"4157_CR211","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1186\/s13287-023-03288-6","volume":"14","author":"L Han","year":"2023","unstructured":"Han L, Zhao Z, He C, Li J, Li X, Lu M (2023) Removing the stumbling block of exosome applications in clinical and translational medicine: expand production and improve accuracy. Stem Cell Res Ther 14:57","journal-title":"Stem Cell Res Ther"}],"container-title":["Neurochemical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11064-024-04157-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11064-024-04157-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11064-024-04157-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,10]],"date-time":"2024-07-10T04:08:21Z","timestamp":1720584501000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11064-024-04157-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,28]]},"references-count":211,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2024,8]]}},"alternative-id":["4157"],"URL":"https:\/\/doi.org\/10.1007\/s11064-024-04157-1","relation":{},"ISSN":["0364-3190","1573-6903"],"issn-type":[{"value":"0364-3190","type":"print"},{"value":"1573-6903","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,28]]},"assertion":[{"value":"16 November 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 March 2024","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 May 2024","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 May 2024","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval and Consent to Participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}]}}