{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T16:52:01Z","timestamp":1790268721861,"version":"4.1.0"},"reference-count":100,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82171359"],"award-info":[{"award-number":["82171359"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82103247"],"award-info":[{"award-number":["82103247"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Tianjin Health Science and Technology Project","award":["TJWJ2022QN060"],"award-info":[{"award-number":["TJWJ2022QN060"]}]},{"name":"Tianjin Key Medical Discipline (Specialty) Construction Project","award":["TJYXZDXK-009A"],"award-info":[{"award-number":["TJYXZDXK-009A"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neurochem Res"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1007\/s11064-024-04202-z","type":"journal-article","created":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T22:01:48Z","timestamp":1719871308000},"page":"2743-2762","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Propofol Protects the Blood-Brain Barrier After Traumatic Brain Injury by Stabilizing the Extracellular Matrix via Prrx1: From Neuroglioma to Neurotrauma"],"prefix":"10.1007","volume":"49","author":[{"given":"Lan","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4933-6918","authenticated-orcid":false,"given":"Chenrui","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiqing","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,7,1]]},"reference":[{"key":"4202_CR1","doi-asserted-by":"publisher","first-page":"2878","DOI":"10.1007\/s00415-019-09541-4","volume":"266","author":"A Khellaf","year":"2019","unstructured":"Khellaf A, Khan DZ, Helmy A (2019) Recent advances in traumatic brain injury. J Neurol 266:2878\u20132889. https:\/\/doi.org\/10.1007\/s00415-019-09541-4","journal-title":"J Neurol"},{"key":"4202_CR2","doi-asserted-by":"publisher","first-page":"1224","DOI":"10.2174\/1570159X15666170613083606","volume":"16","author":"P Kaur","year":"2018","unstructured":"Kaur P, Sharma S (2018) Recent advances in pathophysiology of traumatic brain injury. Curr Neuropharmacol 16:1224\u20131238. https:\/\/doi.org\/10.2174\/1570159X15666170613083606","journal-title":"Curr Neuropharmacol"},{"key":"4202_CR3","doi-asserted-by":"publisher","first-page":"1118","DOI":"10.1177\/0963689717714102","volume":"26","author":"M Galgano","year":"2017","unstructured":"Galgano M, Toshkezi G, Qiu X, Russell T, Chin L, Zhao LR (2017) Traumatic brain injury: current treatment strategies and future endeavors. Cell Transplant 26:1118\u20131130. https:\/\/doi.org\/10.1177\/0963689717714102","journal-title":"Cell Transplant"},{"key":"4202_CR4","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1152\/physrev.00042.2016","volume":"98","author":"A Verkhratsky","year":"2018","unstructured":"Verkhratsky A, Nedergaard M (2018) Physiology of astroglia. Physiol Rev 98:239\u2013389. https:\/\/doi.org\/10.1152\/physrev.00042.2016","journal-title":"Physiol Rev"},{"key":"4202_CR5","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1042\/BJ20111943","volume":"443","author":"S Fernandez-Fernandez","year":"2012","unstructured":"Fernandez-Fernandez S, Almeida A, Bola\u00f1os JP (2012) Antioxidant and bioenergetic coupling between neurons and astrocytes. Biochem J 443:3\u201311. https:\/\/doi.org\/10.1042\/BJ20111943","journal-title":"Biochem J"},{"key":"4202_CR6","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1186\/1742-2094-9-68","volume":"9","author":"H Ralay Ranaivo","year":"2012","unstructured":"Ralay Ranaivo H, Hodge JN, Choi N, Wainwright MS (2012) Albumin induces upregulation of matrix metalloproteinase-9 in astrocytes via MAPK and reactive oxygen species-dependent pathways. J Neuroinflammation 9:68. https:\/\/doi.org\/10.1186\/1742-2094-9-68","journal-title":"J Neuroinflammation"},{"key":"4202_CR7","doi-asserted-by":"publisher","first-page":"1384","DOI":"10.1007\/s00134-008-1056-1","volume":"34","author":"A Vilalta","year":"2008","unstructured":"Vilalta A, Sahuquillo J, Rosell A, Poca MA, Riveiro M, Montaner J (2008) Moderate and severe traumatic brain injury induce early overexpression of systemic and brain gelatinases. Intensive Care Med 34:1384\u20131392. https:\/\/doi.org\/10.1007\/s00134-008-1056-1","journal-title":"Intensive Care Med"},{"key":"4202_CR8","doi-asserted-by":"publisher","first-page":"1717","DOI":"10.1089\/neu.2012.2841","volume":"30","author":"DJ Roberts","year":"2013","unstructured":"Roberts DJ, Jenne CN, L\u00e9ger C, Kramer AH, Gallagher CN, Todd S, Parney IF, Doig CJ, Yong VW, Kubes P, Zygun DA (2013) A prospective evaluation of the temporal matrix metalloproteinase response after severe traumatic brain injury in humans. J Neurotrauma 30:1717\u20131726. https:\/\/doi.org\/10.1089\/neu.2012.2841","journal-title":"J Neurotrauma"},{"key":"4202_CR9","doi-asserted-by":"publisher","first-page":"6963","DOI":"10.1073\/pnas.1118754109","volume":"109","author":"C Yang","year":"2012","unstructured":"Yang C, Iyer RR, Yu AC, Yong RL, Park DM, Weil RJ, Ikejiri B, Brady RO, Lonser RR, Zhuang Z (2012) \u03b2-Catenin signaling initiates the activation of astrocytes and its dysregulation contributes to the pathogenesis of astrocytomas. Proc Natl Acad Sci U S A 109:6963\u20136968. https:\/\/doi.org\/10.1073\/pnas.1118754109","journal-title":"Proc Natl Acad Sci U S A"},{"key":"4202_CR10","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1002\/glia.1052","volume":"34","author":"G Tezel","year":"2001","unstructured":"Tezel G, Hernandez MR, Wax MB (2001) In vitro evaluation of reactive astrocyte migration, a component of tissue remodeling in glaucomatous optic nerve head. Glia 34:178\u2013189. https:\/\/doi.org\/10.1002\/glia.1052","journal-title":"Glia"},{"key":"4202_CR11","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1016\/j.mam.2012.02.003","volume":"33","author":"H Wolburg","year":"2012","unstructured":"Wolburg H, Noell S, Fallier-Becker P, Mack AF, Wolburg-Buchholz K (2012) The disturbed blood-brain barrier in human glioblastoma. Mol Aspects Med 33:579\u2013589. https:\/\/doi.org\/10.1016\/j.mam.2012.02.003","journal-title":"Mol Aspects Med"},{"key":"4202_CR12","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1016\/j.freeradbiomed.2021.12.007","volume":"178","author":"C Wu","year":"2022","unstructured":"Wu C, Du M, Yu R, Cheng Y, Wu B, Fu J, Tan W, Zhou Q, Balawi E, Liao ZB (2022) A novel mechanism linking ferroptosis and endoplasmic reticulum stress via the circPtpn14\/miR-351-5p\/5-LOX signaling in melatonin-mediated treatment of traumatic brain injury. Free Radic Biol Med 178:271\u2013294. https:\/\/doi.org\/10.1016\/j.freeradbiomed.2021.12.007","journal-title":"Free Radic Biol Med"},{"key":"4202_CR13","doi-asserted-by":"publisher","first-page":"4575","DOI":"10.1038\/s41380-022-01711-7","volume":"27","author":"M Du","year":"2022","unstructured":"Du M, Wu C, Yu R, Cheng Y, Tang Z, Wu B, Fu J, Tan W, Zhou Q, Zhu Z, Balawi E, Huang X, Ma J, Liao ZB (2022) A novel circular RNA, circIgfbp2, links neural plasticity and anxiety through targeting mitochondrial dysfunction and oxidative stress-induced synapse dysfunction after traumatic brain injury. Mol Psychiatry 27:4575\u20134589. https:\/\/doi.org\/10.1038\/s41380-022-01711-7","journal-title":"Mol Psychiatry"},{"key":"4202_CR14","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1016\/j.neuropharm.2013.08.029","volume":"77","author":"J Li","year":"2014","unstructured":"Li J, Yu W, Li XT, Qi SH, Li B (2014) The effects of propofol on mitochondrial dysfunction following focal cerebral ischemia-reperfusion in rats. Neuropharmacology 77:358\u2013368. https:\/\/doi.org\/10.1016\/j.neuropharm.2013.08.029","journal-title":"Neuropharmacology"},{"key":"4202_CR15","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1097\/00000542-200601000-00014","volume":"104","author":"C Adembri","year":"2006","unstructured":"Adembri C, Venturi L, Tani A, Chiarugi A, Gramigni E, Cozzi A, Pancani T, De Gaudio RA, Pellegrini-Giampietro DE (2006) Neuroprotective effects of propofol in models of cerebral ischemia: inhibition of mitochondrial swelling as a possible mechanism. Anesthesiology 104:80\u201389. https:\/\/doi.org\/10.1097\/00000542-200601000-00014","journal-title":"Anesthesiology"},{"key":"4202_CR16","doi-asserted-by":"publisher","first-page":"876","DOI":"10.1164\/rccm.202206-1208OC","volume":"207","author":"Y Shehabi","year":"2023","unstructured":"Shehabi Y, Serpa Neto A, Bellomo R, Howe BD, Arabi YM, Bailey M, Bass FE, Bin Kadiman S, McArthur CJ, Reade MC, Seppelt IM, Takala J, Wise MP, Webb SA (2023) Dexmedetomidine and propofol sedation in critically Ill patients and dose-associated 90-day mortality: a secondary cohort analysis of a randomized controlled trial (SPICE III). Am J Respir Crit Care Med 207:876\u2013886. https:\/\/doi.org\/10.1164\/rccm.202206-1208OC","journal-title":"Am J Respir Crit Care Med"},{"key":"4202_CR17","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1101\/gr.269894.120","volume":"31","author":"P Liu","year":"2021","unstructured":"Liu P, Ewald J, Galvez JH, Head J, Crump D, Bourque G, Basu N, Xia J (2021) Ultrafast functional profiling of RNA-seq data for nonmodel organisms. Genome Res 31:713\u2013720. https:\/\/doi.org\/10.1101\/gr.269894.120","journal-title":"Genome Res"},{"key":"4202_CR18","doi-asserted-by":"publisher","first-page":"2995","DOI":"10.1038\/s41467-023-38785-y","volume":"14","author":"P Liu","year":"2023","unstructured":"Liu P, Ewald J, Pang Z, Legrand E, Jeon YS, Sangiovanni J, Hacariz O, Zhou G, Head JA, Basu N, Xia J (2023) ExpressAnalyst: a unified platform for RNA-sequencing analysis in non-model species. Nat Commun 14:2995. https:\/\/doi.org\/10.1038\/s41467-023-38785-y","journal-title":"Nat Commun"},{"key":"4202_CR19","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkv007","volume":"43","author":"ME Ritchie","year":"2015","unstructured":"Ritchie ME, Phipson B, Wu D, Hu Y, Law CW, Shi W, Smyth GK (2015) limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic Acids Res 43:e47. https:\/\/doi.org\/10.1093\/nar\/gkv007","journal-title":"Nucleic Acids Res"},{"key":"4202_CR20","doi-asserted-by":"publisher","first-page":"W212","DOI":"10.1093\/nar\/gkz446","volume":"47","author":"AB Keenan","year":"2019","unstructured":"Keenan AB, Torre D, Lachmann A, Leong AK, Wojciechowicz ML, Utti V, Jagodnik KM, Kropiwnicki E, Wang Z, Ma\u2019ayan A (2019) ChEA3: transcription factor enrichment analysis by orthogonal omics integration. Nucleic Acids Res 47:W212\u2013W224. https:\/\/doi.org\/10.1093\/nar\/gkz446","journal-title":"Nucleic Acids Res"},{"key":"4202_CR21","doi-asserted-by":"publisher","first-page":"D92","DOI":"10.1093\/nar\/gkt1248","volume":"42","author":"JH Li","year":"2014","unstructured":"Li JH, Liu S, Zhou H, Qu LH, Yang JH (2014) starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein-RNA interaction networks from large-scale CLIP-Seq data. Nucleic Acids Res 42:D92-97. https:\/\/doi.org\/10.1093\/nar\/gkt1248","journal-title":"Nucleic Acids Res"},{"key":"4202_CR22","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1016\/0092-8674(95)90468-9","volume":"82","author":"DS Wilson","year":"1995","unstructured":"Wilson DS, Guenther B, Desplan C, Kuriyan J (1995) High resolution crystal structure of a paired (Pax) class cooperative homeodomain dimer on DNA. Cell 82:709\u2013719. https:\/\/doi.org\/10.1016\/0092-8674(95)90468-9","journal-title":"Cell"},{"key":"4202_CR23","doi-asserted-by":"publisher","first-page":"D1074","DOI":"10.1093\/nar\/gkx1037","volume":"46","author":"DS Wishart","year":"2018","unstructured":"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M (2018) DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res 46:D1074\u2013D1082. https:\/\/doi.org\/10.1093\/nar\/gkx1037","journal-title":"Nucleic Acids Res"},{"key":"4202_CR24","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1002\/1097-0134(20010501)43:2<113::aid-prot1023>3.0.co;2-t","volume":"43","author":"DJ Diller","year":"2001","unstructured":"Diller DJ, Merz KM Jr (2001) High throughput docking for library design and library prioritization. Proteins 43:113\u2013124. https:\/\/doi.org\/10.1002\/1097-0134(20010501)43:2%3c113::aid-prot1023%3e3.0.co;2-t","journal-title":"Proteins"},{"key":"4202_CR25","doi-asserted-by":"publisher","first-page":"6373","DOI":"10.1021\/jm049902r","volume":"47","author":"DJ Diller","year":"2004","unstructured":"Diller DJ, Hobbs DW (2004) Deriving knowledge through data mining high-throughput screening data. J Med Chem 47:6373\u20136383. https:\/\/doi.org\/10.1021\/jm049902r","journal-title":"J Med Chem"},{"key":"4202_CR26","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2022.120349","volume":"293","author":"W Niu","year":"2022","unstructured":"Niu W, Duan Y, Kang Y, Cao X, Xue Q (2022) Propofol improves learning and memory in post-traumatic stress disorder (PTSD) mice via recovering hippocampus synaptic plasticity. Life Sci 293:120349. https:\/\/doi.org\/10.1016\/j.lfs.2022.120349","journal-title":"Life Sci"},{"key":"4202_CR27","doi-asserted-by":"publisher","first-page":"1626","DOI":"10.1016\/j.neuron.2023.02.017","volume":"111","author":"XN Zhu","year":"2023","unstructured":"Zhu XN, Li J, Qiu GL, Wang L, Lu C, Guo YG, Yang KX, Cai F, Xu T, Yuan TF, Hu J (2023) Propofol exerts anti-anhedonia effects via inhibiting the dopamine transporter. Neuron 111:1626-1636.e6. https:\/\/doi.org\/10.1016\/j.neuron.2023.02.017","journal-title":"Neuron"},{"key":"4202_CR28","doi-asserted-by":"publisher","first-page":"1616","DOI":"10.1213\/ANE.0000000000004955","volume":"131","author":"Y Nie","year":"2020","unstructured":"Nie Y, Li S, Yan T, Ma Y, Ni C, Wang H, Zheng H (2020) Propofol attenuates isoflurane-induced neurotoxicity and cognitive impairment in fetal and offspring mice. Anesth Analg 131:1616\u20131625. https:\/\/doi.org\/10.1213\/ANE.0000000000004955","journal-title":"Anesth Analg"},{"key":"4202_CR29","doi-asserted-by":"publisher","DOI":"10.1002\/cpim.83","volume":"126","author":"M Goldim","year":"2019","unstructured":"Goldim M, Della Giustina A, Petronilho F (2019) Using evans blue dye to determine blood-brain barrier integrity in rodents. Curr Protoc Immunol 126:e83. https:\/\/doi.org\/10.1002\/cpim.83","journal-title":"Curr Protoc Immunol"},{"key":"4202_CR30","doi-asserted-by":"publisher","first-page":"D155","DOI":"10.1093\/nar\/gky1141","volume":"47","author":"A Kozomara","year":"2019","unstructured":"Kozomara A, Birgaoanu M, Griffiths-Jones S (2019) miRBase: from microRNA sequences to function. Nucleic Acids Res 47:D155\u2013D162. https:\/\/doi.org\/10.1093\/nar\/gky1141","journal-title":"Nucleic Acids Res"},{"key":"4202_CR31","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1097\/ALN.0b013e3182746676","volume":"117","author":"M Ishikawa","year":"2012","unstructured":"Ishikawa M, Tanaka S, Arai M, Genda Y, Sakamoto A (2012) Differences in microRNA changes of healthy rat liver between sevoflurane and propofol anesthesia. Anesthesiology 117:1245\u20131252. https:\/\/doi.org\/10.1097\/ALN.0b013e3182746676","journal-title":"Anesthesiology"},{"key":"4202_CR32","doi-asserted-by":"publisher","first-page":"881","DOI":"10.1039\/c5np00094g","volume":"33","author":"O Callies","year":"2016","unstructured":"Callies O, Hern\u00e1ndez Daranas A (2016) Application of isothermal titration calorimetry as a tool to study natural product interactions. Nat Prod Rep 33:881\u2013904. https:\/\/doi.org\/10.1039\/c5np00094g","journal-title":"Nat Prod Rep"},{"key":"4202_CR33","doi-asserted-by":"publisher","first-page":"801","DOI":"10.3390\/antiox11050801","volume":"11","author":"D Matuz-Mares","year":"2022","unstructured":"Matuz-Mares D, Gonz\u00e1lez-Andrade M, Araiza-Villanueva MG, Vilchis-Landeros MM, V\u00e1zquez-Meza H (2022) Mitochondrial calcium: effects of its imbalance in disease. Antioxidants (Basel) 11:801. https:\/\/doi.org\/10.3390\/antiox11050801","journal-title":"Antioxidants (Basel)"},{"key":"4202_CR34","doi-asserted-by":"publisher","first-page":"3707","DOI":"10.2147\/JIR.S325678","volume":"14","author":"YL Lan","year":"2021","unstructured":"Lan YL, Zhu Y, Chen G, Zhang J (2021) The promoting effect of traumatic brain injury on the incidence and progression of glioma: a review of clinical and experimental research. J Inflamm Res 14:3707\u20133720. https:\/\/doi.org\/10.2147\/JIR.S325678","journal-title":"J Inflamm Res"},{"key":"4202_CR35","doi-asserted-by":"publisher","first-page":"5471","DOI":"10.1021\/acsomega.0c05708","volume":"6","author":"J Hao","year":"2021","unstructured":"Hao J, Zhang W, Tong R, Huang Z (2021) Febuxostat prevents the cytotoxicity of propofol in brain endothelial cells. ACS Omega 6:5471\u20135478. https:\/\/doi.org\/10.1021\/acsomega.0c05708","journal-title":"ACS Omega"},{"key":"4202_CR36","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1093\/bja\/aeg009","volume":"90","author":"AL Dawidowicz","year":"2003","unstructured":"Dawidowicz AL, Fija\u0142kowska A, Nestorowicz A, Kality\u0144ski R, Trojanowski T (2003) Cerebrospinal fluid and blood propofol concentration during total intravenous anaesthesia for neurosurgery. Br J Anaesth 90:84\u201386","journal-title":"Br J Anaesth"},{"key":"4202_CR37","doi-asserted-by":"publisher","DOI":"10.1111\/cpr.12867","volume":"53","author":"Y Xu","year":"2020","unstructured":"Xu Y, Pan S, Jiang W, Xue F, Zhu X (2020) Effects of propofol on the development of cancer in humans. Cell Prolif 53:e12867. https:\/\/doi.org\/10.1111\/cpr.12867","journal-title":"Cell Prolif"},{"key":"4202_CR38","doi-asserted-by":"publisher","first-page":"1024","DOI":"10.1097\/SLA.0000000000005568","volume":"278","author":"S Yoon","year":"2023","unstructured":"Yoon S, Jung SY, Kim MS, Yoon D, Cho Y, Jeon Y (2023) Impact of propofol-based total intravenous anesthesia versus inhalation anesthesia on long-term survival after cancer surgery in a nationwide cohort. Ann Surg 278:1024\u20131031. https:\/\/doi.org\/10.1097\/SLA.0000000000005568","journal-title":"Ann Surg"},{"key":"4202_CR39","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1111\/anae.13331","volume":"71","author":"YJ Xu","year":"2016","unstructured":"Xu YJ, Li SY, Cheng Q, Chen WK, Wang SL, Ren Y, Miao CH (2016) Effects of anaesthesia on proliferation, invasion and apoptosis of LoVo colon cancer cells in vitro. Anaesthesia 71:147\u2013154. https:\/\/doi.org\/10.1111\/anae.13331","journal-title":"Anaesthesia"},{"key":"4202_CR40","doi-asserted-by":"publisher","first-page":"1921","DOI":"10.3390\/cells12151921","volume":"12","author":"R Nizar","year":"2023","unstructured":"Nizar R, Cazacu S, Xiang C, Krasner M, Barbiro-Michaely E, Gerber D, Schwartz J, Fried I, Yuval S, Brodie A, Kazimirsky G, Amos N, Unger R, Brown S, Rogers L, Penning DH, Brodie C (2023) Propofol inhibits glioma stem cell growth and migration and their interaction with microglia via BDNF-AS and extracellular vesicles. Cells 12:1921. https:\/\/doi.org\/10.3390\/cells12151921","journal-title":"Cells"},{"key":"4202_CR41","doi-asserted-by":"publisher","first-page":"2440","DOI":"10.1002\/tox.22458","volume":"32","author":"SS Hsu","year":"2017","unstructured":"Hsu SS, Jan CR, Liang WZ (2017) Evaluation of cytotoxicity of propofol and its related mechanism in glioblastoma cells and astrocytes. Environ Toxicol 32:2440\u20132454. https:\/\/doi.org\/10.1002\/tox.22458","journal-title":"Environ Toxicol"},{"key":"4202_CR42","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2020.590931","volume":"10","author":"C Yang","year":"2020","unstructured":"Yang C, Xia Z, Li T, Chen Y, Zhao M, Sun Y, Ma J, Wu Y, Wang X, Wang P, Wang H (2020) Antioxidant effect of propofol in gliomas and its association with divalent metal transporter 1. Front Oncol 10:590931. https:\/\/doi.org\/10.3389\/fonc.2020.590931","journal-title":"Front Oncol"},{"key":"4202_CR43","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1038\/s41419-021-03882-7","volume":"12","author":"Z Chen","year":"2021","unstructured":"Chen Z, Chen Y, Li Y, Lian W, Zheng K, Zhang Y, Zhang Y, Lin C, Liu C, Sun F, Sun X, Wang J, Zhao L, Ke Y (2021) Prrx1 promotes stemness and angiogenesis via activating TGF-\u03b2\/smad pathway and upregulating proangiogenic factors in glioma. Cell Death Dis 12:615. https:\/\/doi.org\/10.1038\/s41419-021-03882-7","journal-title":"Cell Death Dis"},{"key":"4202_CR44","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1016\/j.ccr.2012.10.012","volume":"22","author":"OH Oca\u00f1a","year":"2012","unstructured":"Oca\u00f1a OH, C\u00f3rcoles R, Fabra A, Moreno-Bueno G, Acloque H, Vega S, Barrallo-Gimeno A, Cano A, Nieto MA (2012) Metastatic colonization requires the repression of the epithelial-mesenchymal transition inducer Prrx1. Cancer Cell 22:709\u2013724. https:\/\/doi.org\/10.1016\/j.ccr.2012.10.012","journal-title":"Cancer Cell"},{"key":"4202_CR45","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1007\/s12032-014-0393-x","volume":"32","author":"J Guo","year":"2015","unstructured":"Guo J, Fu Z, Wei J, Lu W, Feng J, Zhang S (2015) PRRX1 promotes epithelial-mesenchymal transition through the Wnt\/\u03b2-catenin pathway in gastric cancer. Med Oncol 32:393. https:\/\/doi.org\/10.1007\/s12032-014-0393-x","journal-title":"Med Oncol"},{"key":"4202_CR46","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1038\/bjc.2013.339","volume":"109","author":"Y Takahashi","year":"2013","unstructured":"Takahashi Y, Sawada G, Kurashige J, Uchi R, Matsumura T, Ueo H, Takano Y, Akiyoshi S, Eguchi H, Sudo T, Sugimachi K, Doki Y, Mori M, Mimori K (2013) Paired related homoeobox 1, a new EMT inducer, is involved in metastasis and poor prognosis in colorectal cancer. Br J Cancer 109:307\u2013311. https:\/\/doi.org\/10.1038\/bjc.2013.339","journal-title":"Br J Cancer"},{"key":"4202_CR47","doi-asserted-by":"publisher","first-page":"4325","DOI":"10.1038\/s41388-019-0725-6","volume":"38","author":"B Marchand","year":"2019","unstructured":"Marchand B, Pitarresi JR, Reichert M, Suzuki K, Laczk\u00f3 D, Rustgi AK (2019) PRRX1 isoforms cooperate with FOXM1 to regulate the DNA damage response in pancreatic cancer cells. Oncogene 38:4325\u20134339. https:\/\/doi.org\/10.1038\/s41388-019-0725-6","journal-title":"Oncogene"},{"key":"4202_CR48","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1093\/jmcb\/mjx017","volume":"9","author":"Y Li","year":"2017","unstructured":"Li Y, Wang W, Wang F, Wu Q, Li W, Zhong X, Tian K, Zeng T, Gao L, Liu Y, Li S, Jiang X, Du G, Zhou Y (2017) Paired related homeobox 1 transactivates dopamine D2 receptor to maintain propagation and tumorigenicity of glioma-initiating cells. J Mol Cell Biol 9:302\u2013314. https:\/\/doi.org\/10.1093\/jmcb\/mjx017","journal-title":"J Mol Cell Biol"},{"key":"4202_CR49","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1080\/21655979.2021.2012549","volume":"13","author":"X Zhang","year":"2022","unstructured":"Zhang X, Ma L, Shen Y, Zhang C, Hou B, Zhou Y (2022) Transcription factor paired related homeobox 1 (PRRX1) activates matrix metalloproteinases (MMP)13, which promotes the dextran sulfate sodium-induced inflammation and barrier dysfunction of NCM460 cells. Bioengineered 13:645\u2013654. https:\/\/doi.org\/10.1080\/21655979.2021.2012549","journal-title":"Bioengineered"},{"key":"4202_CR50","doi-asserted-by":"publisher","first-page":"20164","DOI":"10.1038\/s41598-020-77406-2","volume":"10","author":"SN Dankel","year":"2020","unstructured":"Dankel SN, Grytten E, Bjune JI, Nielsen HJ, Dietrich A, Bl\u00fcher M, Sagen JV, Mellgren G (2020) COL6A3 expression in adipose tissue cells is associated with levels of the homeobox transcription factor PRRX1. Sci Rep 10:20164. https:\/\/doi.org\/10.1038\/s41598-020-77406-2","journal-title":"Sci Rep"},{"key":"4202_CR51","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1038\/nature12986","volume":"505","author":"Y Tay","year":"2014","unstructured":"Tay Y, Rinn J, Pandolfi PP (2014) The multilayered complexity of ceRNA crosstalk and competition. Nature 505:344\u2013352. https:\/\/doi.org\/10.1038\/nature12986","journal-title":"Nature"},{"key":"4202_CR52","doi-asserted-by":"publisher","first-page":"3971","DOI":"10.1073\/pnas.71.10.3971","volume":"71","author":"R Desrosiers","year":"1974","unstructured":"Desrosiers R, Friderici K, Rottman F (1974) Identification of methylated nucleosides in messenger RNA from Novikoff hepatoma cells. Proc Natl Acad Sci U S A 71:3971\u20133975. https:\/\/doi.org\/10.1073\/pnas.71.10.3971","journal-title":"Proc Natl Acad Sci U S A"},{"key":"4202_CR53","doi-asserted-by":"publisher","first-page":"482","DOI":"10.1038\/nature14281","volume":"519","author":"CR Alarc\u00f3n","year":"2015","unstructured":"Alarc\u00f3n CR, Lee H, Goodarzi H, Halberg N, Tavazoie SF (2015) N6-methyladenosine marks primary microRNAs for processing. Nature 519:482\u2013485. https:\/\/doi.org\/10.1038\/nature14281","journal-title":"Nature"},{"key":"4202_CR54","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1038\/nchembio.1432","volume":"10","author":"J Liu","year":"2014","unstructured":"Liu J, Yue Y, Han D, Wang X, Fu Y, Zhang L, Jia G, Yu M, Lu Z, Deng X, Dai Q, Chen W, He C (2014) A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation. Nat Chem Biol 10:93\u201395. https:\/\/doi.org\/10.1038\/nchembio.1432","journal-title":"Nat Chem Biol"},{"key":"4202_CR55","doi-asserted-by":"publisher","first-page":"681","DOI":"10.1038\/s41419-020-02828-9","volume":"11","author":"Y Lu","year":"2020","unstructured":"Lu Y, Wang S, Cai S, Gu X, Wang J, Yang Y, Hu Z, Zhang X, Ye Y, Shen S, Joshi K, Ma D, Zhang L (2020) Propofol-induced MiR-20b expression initiates endogenous cellular signal changes mitigating hypoxia\/re-oxygenation-induced endothelial autophagy in vitro. Cell Death Dis 11:681. https:\/\/doi.org\/10.1038\/s41419-020-02828-9","journal-title":"Cell Death Dis"},{"key":"4202_CR56","doi-asserted-by":"publisher","first-page":"1406","DOI":"10.1161\/01.RES.0000133228.54181.cd","volume":"94","author":"RW Dettman","year":"2004","unstructured":"Dettman RW, Steinhorn RH (2004) Connecting the cells: vascular differentiation via homeobox genes and extracellular matrix in the distal lung. Circ Res 94:1406\u20131407. https:\/\/doi.org\/10.1161\/01.RES.0000133228.54181.cd","journal-title":"Circ Res"},{"key":"4202_CR57","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1053\/j.gastro.2020.09.010","volume":"160","author":"K Feldmann","year":"2021","unstructured":"Feldmann K, Maurer C, Peschke K, Teller S, Schuck K, Steiger K, Engleitner T, \u00d6llinger R, Nomura A, Wirges N, Papargyriou A, Jahan Sarker RS, Ranjan RA, Dantes Z, Weichert W, Rustgi AK, Schmid RM, Rad R, Schneider G, Saur D, Reichert M (2021) Mesenchymal plasticity regulated by Prrx1 drives aggressive pancreatic cancer biology. Gastroenterology 160:346-361.e24. https:\/\/doi.org\/10.1053\/j.gastro.2020.09.010","journal-title":"Gastroenterology"},{"key":"4202_CR58","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1016\/s0945-053x(97)90033-0","volume":"15","author":"P Maurer","year":"1997","unstructured":"Maurer P, Hohenester E (1997) Structural and functional aspects of calcium binding in extracellular matrix proteins. Matrix Biol 15:569\u2013580. https:\/\/doi.org\/10.1016\/s0945-053x(97)90033-0","journal-title":"Matrix Biol"},{"key":"4202_CR59","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1016\/s0955-0674(96)80101-3","volume":"8","author":"P Maurer","year":"1996","unstructured":"Maurer P, Hohenester E, Engel J (1996) Extracellular calcium-binding proteins. Curr Opin Cell Biol 8:609\u2013617. https:\/\/doi.org\/10.1016\/s0955-0674(96)80101-3","journal-title":"Curr Opin Cell Biol"},{"key":"4202_CR60","doi-asserted-by":"publisher","first-page":"1079","DOI":"10.1007\/978-3-030-12457-1_43","volume":"1131","author":"S Gopal","year":"2020","unstructured":"Gopal S, Multhaupt H, Couchman JR (2020) Calcium in cell-extracellular matrix interactions. Adv Exp Med Biol 1131:1079\u20131102. https:\/\/doi.org\/10.1007\/978-3-030-12457-1_43","journal-title":"Adv Exp Med Biol"},{"key":"4202_CR61","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2020.101678","volume":"36","author":"CT Madreiter-Sokolowski","year":"2020","unstructured":"Madreiter-Sokolowski CT, Thomas C, Ristow M (2020) Interrelation between ROS and Ca(2+) in aging and age-related diseases. Redox Biol 36:101678. https:\/\/doi.org\/10.1016\/j.redox.2020.101678","journal-title":"Redox Biol"},{"key":"4202_CR62","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1186\/1742-2094-8-78","volume":"8","author":"M Khan","year":"2011","unstructured":"Khan M, Sakakima H, Dhammu TS, Shunmugavel A, Im YB, Gilg AG, Singh AK, Singh I (2011) S-nitrosoglutathione reduces oxidative injury and promotes mechanisms of neurorepair following traumatic brain injury in rats. J Neuroinflammation 8:78. https:\/\/doi.org\/10.1186\/1742-2094-8-78","journal-title":"J Neuroinflammation"},{"key":"4202_CR63","doi-asserted-by":"publisher","first-page":"1254","DOI":"10.1097\/00000542-199512000-00016","volume":"83","author":"P Amorim","year":"1995","unstructured":"Amorim P, Chambers G, Cottrell J, Kass IS (1995) Propofol reduces neuronal transmission damage and attenuates the changes in calcium, potassium, and sodium during hyperthermic anoxia in the rat hippocampal slice. Anesthesiology 83:1254\u20131265. https:\/\/doi.org\/10.1097\/00000542-199512000-00016","journal-title":"Anesthesiology"},{"key":"4202_CR64","doi-asserted-by":"publisher","first-page":"C252","DOI":"10.1152\/ajpcell.00151.2018","volume":"316","author":"DN Edwards","year":"2019","unstructured":"Edwards DN, Bix GJ (2019) Roles of blood-brain barrier integrins and extracellular matrix in stroke. Am J Physiol Cell Physiol 316:C252\u2013C263. https:\/\/doi.org\/10.1152\/ajpcell.00151.2018","journal-title":"Am J Physiol Cell Physiol"},{"key":"4202_CR65","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1007\/s00401-002-0524-x","volume":"104","author":"G Rascher","year":"2002","unstructured":"Rascher G, Fischmann A, Kr\u00f6ger S, Duffner F, Grote EH, Wolburg H (2002) Extracellular matrix and the blood-brain barrier in glioblastoma multiforme: spatial segregation of tenascin and agrin. Acta Neuropathol 104:85\u201391. https:\/\/doi.org\/10.1007\/s00401-002-0524-x","journal-title":"Acta Neuropathol"},{"key":"4202_CR66","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/s0166-2236(97)01169-7","volume":"21","author":"VW Yong","year":"1998","unstructured":"Yong VW, Krekoski CA, Forsyth PA, Bell R, Edwards DR (1998) Matrix metalloproteinases and diseases of the CNS. Trends Neurosci 21:75\u201380. https:\/\/doi.org\/10.1016\/s0166-2236(97)01169-7","journal-title":"Trends Neurosci"},{"key":"4202_CR67","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1007\/BF00691095","volume":"72","author":"I Klatzo","year":"1987","unstructured":"Klatzo I (1987) Pathophysiological aspects of brain edema. Acta Neuropathol 72:236\u2013239. https:\/\/doi.org\/10.1007\/BF00691095","journal-title":"Acta Neuropathol"},{"key":"4202_CR68","doi-asserted-by":"publisher","first-page":"418","DOI":"10.3389\/fncel.2014.00418","volume":"8","author":"LG Dubois","year":"2014","unstructured":"Dubois LG, Campanati L, Righy C, D\u2019Andrea-Meira I, Spohr TC, Porto-Carreiro I, Pereira CM, Bal\u00e7a-Silva J, Kahn SA, DosSantos MF, Oliveira Mde A, Ximenes-da-Silva A, Lopes MC, Faveret E, Gasparetto EL, Moura-Neto V (2014) Gliomas and the vascular fragility of the blood brain barrier. Front Cell Neurosci 8:418. https:\/\/doi.org\/10.3389\/fncel.2014.00418","journal-title":"Front Cell Neurosci"},{"key":"4202_CR69","doi-asserted-by":"publisher","first-page":"1788","DOI":"10.3390\/ijms18081788","volume":"18","author":"AJ Sorby-Adams","year":"2017","unstructured":"Sorby-Adams AJ, Marcoionni AM, Dempsey ER, Woenig JA, Turner RJ (2017) The role of neurogenic inflammation in blood-brain barrier disruption and development of cerebral oedema following acute central nervous system (CNS) injury. Int J Mol Sci 18:1788. https:\/\/doi.org\/10.3390\/ijms18081788","journal-title":"Int J Mol Sci"},{"key":"4202_CR70","doi-asserted-by":"publisher","first-page":"E2","DOI":"10.3171\/foc.2007.22.5.3","volume":"22","author":"D Liang","year":"2007","unstructured":"Liang D, Bhatta S, Gerzanich V, Simard JM (2007) Cytotoxic edema: mechanisms of pathological cell swelling. Neurosurg Focus 22:E2. https:\/\/doi.org\/10.3171\/foc.2007.22.5.3","journal-title":"Neurosurg Focus"},{"key":"4202_CR71","doi-asserted-by":"publisher","first-page":"418","DOI":"10.1007\/s00401-005-0984-x","volume":"109","author":"A Warth","year":"2005","unstructured":"Warth A, Mittelbronn M, Wolburg H (2005) Redistribution of the water channel protein aquaporin-4 and the K+ channel protein Kir4.1 differs in low- and high-grade human brain tumors. Acta Neuropathol 109:418\u2013426. https:\/\/doi.org\/10.1007\/s00401-005-0984-x","journal-title":"Acta Neuropathol"},{"key":"4202_CR72","doi-asserted-by":"publisher","first-page":"784","DOI":"10.1016\/j.cell.2020.03.037","volume":"181","author":"P Kitchen","year":"2020","unstructured":"Kitchen P, Salman MM, Halsey AM, Clarke-Bland C, MacDonald JA, Ishida H, Vogel HJ, Almutiri S, Logan A, Kreida S, Al-Jubair T, Winkel Missel J, Gourdon P, T\u00f6rnroth-Horsefield S, Conner MT, Ahmed Z, Conner AC, Bill RM (2020) Targeting aquaporin-4 subcellular localization to treat central nervous system edema. Cell 181:784-799.e19. https:\/\/doi.org\/10.1016\/j.cell.2020.03.037","journal-title":"Cell"},{"key":"4202_CR73","doi-asserted-by":"publisher","first-page":"5612","DOI":"10.1158\/1078-0432.CCR-14-0834","volume":"20","author":"TT Batchelor","year":"2014","unstructured":"Batchelor TT, Reardon DA, de Groot JF, Wick W, Weller M (2014) Antiangiogenic therapy for glioblastoma: current status and future prospects. Clin Cancer Res 20:5612\u20135619. https:\/\/doi.org\/10.1158\/1078-0432.CCR-14-0834","journal-title":"Clin Cancer Res"},{"key":"4202_CR74","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1097\/WCO.0b013e328337f451","volume":"23","author":"JJ Donkin","year":"2010","unstructured":"Donkin JJ, Vink R (2010) Mechanisms of cerebral edema in traumatic brain injury: therapeutic developments. Curr Opin Neurol 23:293\u2013299. https:\/\/doi.org\/10.1097\/WCO.0b013e328337f451","journal-title":"Curr Opin Neurol"},{"key":"4202_CR75","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1089\/neu.2023.0222","volume":"41","author":"S Hu","year":"2024","unstructured":"Hu S, Exner C, Sienel RI, When AC, Seker FB, Boldoczki FM, Guo Y, Duering M, Pasternak O, Plesnila N, Schwarzmaier SM (2024) Characterization of vasogenic and cytotoxic brain edema formation after experimental traumatic brain injury by free water diffusion magnetic resonance imaging. J Neurotrauma 41:393\u2013406. https:\/\/doi.org\/10.1089\/neu.2023.0222","journal-title":"J Neurotrauma"},{"key":"4202_CR76","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1227\/NEU.0000000000001432","volume":"80","author":"N Carney","year":"2017","unstructured":"Carney N, Totten AM, O\u2019Reilly C, Ullman JS, Hawryluk GW, Bell MJ, Bratton SL, Chesnut R, Harris OA, Kissoon N, Rubiano AM, Shutter L, Tasker RC, Vavilala MS, Wilberger J, Wright DW, Ghajar J (2017) Guidelines for the management of severe traumatic brain injury. Neurosurgery 80:6\u201315. https:\/\/doi.org\/10.1227\/NEU.0000000000001432","journal-title":"Neurosurgery"},{"key":"4202_CR77","doi-asserted-by":"publisher","first-page":"746","DOI":"10.1056\/NEJMct1206321","volume":"367","author":"AH Ropper","year":"2012","unstructured":"Ropper AH (2012) Hyperosmolar therapy for raised intracranial pressure. N Engl J Med 367:746\u2013752. https:\/\/doi.org\/10.1056\/NEJMct1206321","journal-title":"N Engl J Med"},{"key":"4202_CR78","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1016\/S1474-4422(20)30003-X","volume":"19","author":"MJ Rowland","year":"2020","unstructured":"Rowland MJ, Veenith T, Hutchinson PJ, Perkins GD (2020) Osmotherapy in traumatic brain injury. Lancet Neurol 19:208. https:\/\/doi.org\/10.1016\/S1474-4422(20)30003-X","journal-title":"Lancet Neurol"},{"key":"4202_CR79","doi-asserted-by":"publisher","first-page":"2056","DOI":"10.1001\/jama.2021.5561","volume":"325","author":"A Roquilly","year":"2021","unstructured":"Roquilly A, Moyer JD, Huet O, Lasocki S, Cohen B, Dahyot-Fizelier C, Chalard K, Seguin P, Jeantrelle C, Vermeersch V, Gaillard T, Cinotti R, Demeure Dit Latte D, Mahe PJ, Vourc\u2019h M, Martin FP, Chopin A, Lerebourg C, Flet L, Chiffoleau A, Feuillet F, Asehnoune K (2021) Effect of continuous infusion of hypertonic saline vs standard care on 6-month neurological outcomes in patients with traumatic brain injury: the COBI randomized clinical trial. JAMA 325:2056\u20132066. https:\/\/doi.org\/10.1001\/jama.2021.5561","journal-title":"JAMA"},{"key":"4202_CR80","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1097\/ACO.0b013e32834458af","volume":"24","author":"AC Lukaszewicz","year":"2011","unstructured":"Lukaszewicz AC, Soyer B, Payen D (2011) Water, water, everywhere: sodium and water balance and the injured brain. Curr Opin Anaesthesiol 24:138\u2013143. https:\/\/doi.org\/10.1097\/ACO.0b013e32834458af","journal-title":"Curr Opin Anaesthesiol"},{"key":"4202_CR81","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1007\/s12028-015-0189-7","volume":"24","author":"KN Sheth","year":"2016","unstructured":"Sheth KN, Elm JJ, Beslow LA, Sze GK, Kimberly WT (2016) Glyburide advantage in malignant edema and stroke (GAMES-RP) trial: rationale and design. Neurocrit Care 24:132\u2013139. https:\/\/doi.org\/10.1007\/s12028-015-0189-7","journal-title":"Neurocrit Care"},{"key":"4202_CR82","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1016\/j.jhep.2010.06.041","volume":"54","author":"AR Jayakumar","year":"2011","unstructured":"Jayakumar AR, Valdes V, Norenberg MD (2011) The Na\u2013K\u2013Cl cotransporter in the brain edema of acute liver failure. J Hepatol 54:272\u2013278. https:\/\/doi.org\/10.1016\/j.jhep.2010.06.041","journal-title":"J Hepatol"},{"key":"4202_CR83","doi-asserted-by":"publisher","first-page":"1046","DOI":"10.1097\/01.WCB.0000130867.32663.90","volume":"24","author":"ME O\u2019Donnell","year":"2004","unstructured":"O\u2019Donnell ME, Tran L, Lam TI, Liu XB, Anderson SE (2004) Bumetanide inhibition of the blood-brain barrier Na\u2013K\u2013Cl cotransporter reduces edema formation in the rat middle cerebral artery occlusion model of stroke. J Cereb Blood Flow Metab 24:1046\u20131056. https:\/\/doi.org\/10.1097\/01.WCB.0000130867.32663.90","journal-title":"J Cereb Blood Flow Metab"},{"key":"4202_CR84","doi-asserted-by":"publisher","first-page":"917","DOI":"10.1097\/CCM.0B013E31816590C4","volume":"36","author":"KT Lu","year":"2008","unstructured":"Lu KT, Cheng NC, Wu CY, Yang YL (2008) NKCC1-mediated traumatic brain injury-induced brain edema and neuron death via Raf\/MEK\/MAPK cascade. Crit Care Med 36:917\u2013922. https:\/\/doi.org\/10.1097\/CCM.0B013E31816590C4","journal-title":"Crit Care Med"},{"key":"4202_CR85","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1186\/s12974-022-02430-0","volume":"19","author":"J Hu","year":"2022","unstructured":"Hu J, Wang X, Chen X, Fang Y, Chen K, Peng W, Wang Z, Guo K, Tan X, Liang F, Lin L, Xiong Y (2022) Hydroxychloroquine attenuates neuroinflammation following traumatic brain injury by regulating the TLR4\/NF-\u03baB signaling pathway. J Neuroinflammation 19:71. https:\/\/doi.org\/10.1186\/s12974-022-02430-0","journal-title":"J Neuroinflammation"},{"key":"4202_CR86","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2023.110683","volume":"107","author":"S Wu","year":"2023","unstructured":"Wu S, Wang J, Liu J, Zhu H, Li R, Wan X, Lei J, Li Y, You C, Hu F, Zhang S, Zhao K, Shu K, Lei T (2023) Programmed cell death 10 increased blood-brain barrier permeability through HMGB1\/TLR4 mediated downregulation of endothelial ZO-1 in glioblastoma. Cell Signal 107:110683. https:\/\/doi.org\/10.1016\/j.cellsig.2023.110683","journal-title":"Cell Signal"},{"key":"4202_CR87","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1038\/72256","volume":"6","author":"GT Manley","year":"2000","unstructured":"Manley GT, Fujimura M, Ma T, Noshita N, Filiz F, Bollen AW, Chan P, Verkman AS (2000) Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke. Nat Med 6:159\u2013163. https:\/\/doi.org\/10.1038\/72256","journal-title":"Nat Med"},{"key":"4202_CR88","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1089\/neu.2008.0782","volume":"27","author":"G Fazzina","year":"2010","unstructured":"Fazzina G, Amorini AM, Marmarou CR, Fukui S, Okuno K, Dunbar JG, Glisson R, Marmarou A, Kleindienst A (2010) The protein kinase C activator phorbol myristate acetate decreases brain edema by aquaporin 4 downregulation after middle cerebral artery occlusion in the rat. J Neurotrauma 27:453\u2013461. https:\/\/doi.org\/10.1089\/neu.2008.0782","journal-title":"J Neurotrauma"},{"key":"4202_CR89","doi-asserted-by":"publisher","first-page":"510","DOI":"10.1016\/s0166-2236(98)01298-3","volume":"21","author":"MR Celio","year":"1998","unstructured":"Celio MR, Spreafico R, De Biasi S, Vitellaro-Zuccarello L (1998) Perineuronal nets: past and present. Trends Neurosci 21:510\u2013515. https:\/\/doi.org\/10.1016\/s0166-2236(98)01298-3","journal-title":"Trends Neurosci"},{"key":"4202_CR90","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1038\/s41583-019-0196-3","volume":"20","author":"JW Fawcett","year":"2019","unstructured":"Fawcett JW, Oohashi T, Pizzorusso T (2019) The roles of perineuronal nets and the perinodal extracellular matrix in neuronal function. Nat Rev Neurosci 20:451\u2013465. https:\/\/doi.org\/10.1038\/s41583-019-0196-3","journal-title":"Nat Rev Neurosci"},{"key":"4202_CR91","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1038\/s41586-019-1563-y","volume":"573","author":"HS Venkatesh","year":"2019","unstructured":"Venkatesh HS, Morishita W, Geraghty AC, Silverbush D, Gillespie SM, Arzt M, Tam LT, Espenel C, Ponnuswami A, Ni L, Woo PJ, Taylor KR, Agarwal A, Regev A, Brang D, Vogel H, Hervey-Jumper S, Bergles DE, Suv\u00e0 ML, Malenka RC, Monje M (2019) Electrical and synaptic integration of glioma into neural circuits. Nature 573:539\u2013545. https:\/\/doi.org\/10.1038\/s41586-019-1563-y","journal-title":"Nature"},{"key":"4202_CR92","doi-asserted-by":"publisher","first-page":"532","DOI":"10.1038\/s41586-019-1564-x","volume":"573","author":"V Venkataramani","year":"2019","unstructured":"Venkataramani V, Tanev DI, Strahle C, Studier-Fischer A, Fankhauser L, Kessler T, K\u00f6rber C, Kardorff M, Ratliff M, Xie R, Horstmann H, Messer M, Paik SP, Knabbe J, Sahm F, Kurz FT, Acikg\u00f6z AA, Herrmannsd\u00f6rfer F, Agarwal A, Bergles DE, Chalmers A, Miletic H, Turcan S, Mawrin C, H\u00e4nggi D, Liu HK, Wick W, Winkler F, Kuner T (2019) Glutamatergic synaptic input to glioma cells drives brain tumour progression. Nature 573:532\u2013538. https:\/\/doi.org\/10.1038\/s41586-019-1564-x","journal-title":"Nature"},{"key":"4202_CR93","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1038\/s41586-023-06678-1","volume":"623","author":"KR Taylor","year":"2023","unstructured":"Taylor KR, Barron T, Hui A, Spitzer A, Yal\u00e7in B, Ivec AE, Geraghty AC, Hartmann GG, Arzt M, Gillespie SM, Kim YS, Maleki Jahan S, Zhang H, Shamardani K, Su M, Ni L, Du PP, Woo PJ, Silva-Torres A, Venkatesh HS, Mancusi R, Ponnuswami A, Mulinyawe S, Keough MB, Chau I, Aziz-Bose R, Tirosh I, Suv\u00e0 ML, Monje M (2023) Glioma synapses recruit mechanisms of adaptive plasticity. Nature 623:366\u2013374. https:\/\/doi.org\/10.1038\/s41586-023-06678-1","journal-title":"Nature"},{"key":"4202_CR94","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1038\/s41586-022-04719-9","volume":"606","author":"P Chen","year":"2022","unstructured":"Chen P, Wang W, Liu R, Lyu J, Zhang L, Li B, Qiu B, Tian A, Jiang W, Ying H, Jing R, Wang Q, Zhu K, Bai R, Zeng L, Duan S, Liu C (2022) Olfactory sensory experience regulates gliomagenesis via neuronal IGF1. Nature 606:550\u2013556. https:\/\/doi.org\/10.1038\/s41586-022-04719-9","journal-title":"Nature"},{"key":"4202_CR95","doi-asserted-by":"publisher","first-page":"844","DOI":"10.1038\/s41586-023-06267-2","volume":"619","author":"E Huang-Hobbs","year":"2023","unstructured":"Huang-Hobbs E, Cheng YT, Ko Y, Luna-Figueroa E, Lozzi B, Taylor KR, McDonald M, He P, Chen HC, Yang Y, Maleki E, Lee ZF, Murali S, Williamson MR, Choi D, Curry R, Bayley J, Woo J, Jalali A, Monje M, Noebels JL, Harmanci AS, Rao G, Deneen B (2023) Remote neuronal activity drives glioma progression through SEMA4F. Nature 619:844\u2013850. https:\/\/doi.org\/10.1038\/s41586-023-06267-2","journal-title":"Nature"},{"key":"4202_CR96","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1038\/s41586-021-03580-6","volume":"594","author":"Y Pan","year":"2021","unstructured":"Pan Y, Hysinger JD, Barron T, Schindler NF, Cobb O, Guo X, Yal\u00e7\u0131n B, Anastasaki C, Mulinyawe SB, Ponnuswami A, Scheaffer S, Ma Y, Chang KC, Xia X, Toonen JA, Lennon JJ, Gibson EM, Huguenard JR, Liau LM, Goldberg JL, Monje M, Gutmann DH (2021) NF1 mutation drives neuronal activity-dependent initiation of optic glioma. Nature 594:277\u2013282. https:\/\/doi.org\/10.1038\/s41586-021-03580-6","journal-title":"Nature"},{"key":"4202_CR97","doi-asserted-by":"publisher","first-page":"2899","DOI":"10.1016\/j.cell.2022.06.054","volume":"185","author":"V Venkataramani","year":"2022","unstructured":"Venkataramani V, Yang Y, Schubert MC, Reyhan E, Tetzlaff SK, Wi\u00dfmann N, Botz M, Soyka SJ, Beretta CA, Pramatarov RL, Fankhauser L, Garofano L, Freudenberg A, Wagner J, Tanev DI, Ratliff M, Xie R, Kessler T, Hoffmann DC, Hai L, D\u00f6rflinger Y, Hoppe S, Yabo YA, Golebiewska A, Niclou SP, Sahm F, Lasorella A, Slowik M, D\u00f6ring L, Iavarone A, Wick W, Kuner T, Winkler F (2022) Glioblastoma hijacks neuronal mechanisms for brain invasion. Cell 185:2899-2917.e31. https:\/\/doi.org\/10.1016\/j.cell.2022.06.054","journal-title":"Cell"},{"key":"4202_CR98","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/j.cell.2018.08.031","volume":"175","author":"CT Walsh","year":"2018","unstructured":"Walsh CT (2018) Propofol: milk of amnesia. Cell 175:10\u201313. https:\/\/doi.org\/10.1016\/j.cell.2018.08.031","journal-title":"Cell"},{"key":"4202_CR99","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1007\/s11910-020-01060-4","volume":"20","author":"S Singla","year":"2020","unstructured":"Singla S, Garcia GE, Rovenolt GE, Soto AL, Gilmore EJ, Hirsch LJ, Blumenfeld H, Sheth KN, Omay SB, Struck AF, Westover MB, Kim JA (2020) Detecting seizures and epileptiform abnormalities in acute brain injury. Curr Neurol Neurosci Rep 20:42. https:\/\/doi.org\/10.1007\/s11910-020-01060-4","journal-title":"Curr Neurol Neurosci Rep"},{"key":"4202_CR100","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1590\/1980-57642016dn11-010002","volume":"11","author":"JN Ianof","year":"2017","unstructured":"Ianof JN, Anghinah R (2017) Traumatic brain injury: An EEG point of view. Dement Neuropsychol 11:3\u20135. https:\/\/doi.org\/10.1590\/1980-57642016dn11-010002","journal-title":"Dement Neuropsychol"}],"container-title":["Neurochemical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11064-024-04202-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11064-024-04202-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11064-024-04202-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,31]],"date-time":"2024-08-31T17:13:08Z","timestamp":1725124388000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11064-024-04202-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,1]]},"references-count":100,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["4202"],"URL":"https:\/\/doi.org\/10.1007\/s11064-024-04202-z","relation":{},"ISSN":["0364-3190","1573-6903"],"issn-type":[{"value":"0364-3190","type":"print"},{"value":"1573-6903","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,1]]},"assertion":[{"value":"30 March 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 June 2024","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 June 2024","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 July 2024","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that there are no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}},{"value":"All animal studies were conducted in accordance with the Guide for the Care and Use of Laboratory Animals and were approved by the Tianjin Medical University General Hospital Animal Care and Use Committee.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}},{"value":"Since this study does not involve human experiments, consent to participate is not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"Since this study does not involve human experiments, consent to publish is not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}}]}}