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All efforts were made to minimize animal discomfort. The experimental protocol was approved by the animal ethics committee of Shaanxi Provincial People\u2019s Hospital to ensure compliance with the \u201cRegulations for the Administration of Laboratory Animals\u201d and the 3R principles (Replacement, Reduction, Refinement), with the ethics approval number 2024\u00a0K-226.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}}],"article-number":"146"}}