{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T06:37:17Z","timestamp":1790491037900,"version":"4.1.0"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2010,9,22]],"date-time":"2010-09-22T00:00:00Z","timestamp":1285113600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharm Res"],"published-print":{"date-parts":[[2011,2]]},"DOI":"10.1007\/s11095-010-0283-7","type":"journal-article","created":{"date-parts":[[2010,9,21]],"date-time":"2010-09-21T17:51:14Z","timestamp":1285091474000},"page":"413-416","source":"Crossref","is-referenced-by-count":42,"title":["Application of Alpha7 Nicotinic Acetylcholine Receptor Agonists in Inflammatory Diseases: An Overview"],"prefix":"10.1007","volume":"28","author":[{"given":"Mario B.","family":"Marrero","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Merouane","family":"Bencherif","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick M.","family":"Lippiello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rudolf","family":"Lucas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2010,9,22]]},"reference":[{"key":"283_CR1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.brainres.2008.11.053","volume":"1256","author":"MB Marrero","year":"2009","unstructured":"Marrero MB, Bencherif M. Convergence of alpha 7 nicotinic acetylcholine receptor-activated pathways for anti-apoptosis and anti-inflammation: central role for JAK2 activation of STAT3 and NF-kappaB. Brain Res. 2009;1256:1\u20137.","journal-title":"Brain Res"},{"key":"283_CR2","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/j.tips.2005.05.007","volume":"26","author":"JJ Buccafusco","year":"2005","unstructured":"Buccafusco JJ, Letchworth SR, Bencherif M, Lippiello PM. Long-lasting cognitive improvement with nicotinic receptor agonists: mechanisms of pharmacokinetic-pharmacodynamic discordance. Trends Pharmacol Sci. 2005;26:352\u201360.","journal-title":"Trends Pharmacol Sci"},{"key":"283_CR3","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1124\/jpet.109.154633","volume":"332","author":"MB Marrero","year":"2010","unstructured":"Marrero MB, Lucas R, Salet C, Hauser TA, Mazurov A, Lippiello PM, et al. An alpha7 nicotinic acetylcholine receptor-selective agonist reduces weight gain and metabolic changes in a mouse model of diabetes. J Pharmacol Exp Ther. 2010;332:173\u201380.","journal-title":"J Pharmacol Exp Ther"},{"key":"283_CR4","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1084\/jem.20040463","volume":"201","author":"RW Saeed","year":"2005","unstructured":"Saeed RW, Varma S, Peng-Nemeroff T, Sherry B, Balakhaneh D, Huston J, et al. Cholinergic stimulation blocks endothelial cell activation and leukocyte recruitment during inflammation. J Exp Med. 2005;201:1113\u201323.","journal-title":"J Exp Med"},{"issue":"6921","key":"283_CR5","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1038\/nature01339","volume":"421","author":"H Wang","year":"2003","unstructured":"Wang H, Yu M, Ochani M, Amella CA, Tanovic M, Susarla S, et al. Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation. Nature. 2003;421(6921):384\u20138.","journal-title":"Nature"},{"key":"283_CR6","doi-asserted-by":"crossref","first-page":"44920","DOI":"10.1074\/jbc.M204610200","volume":"277","author":"S Shaw","year":"2002","unstructured":"Shaw S, Bencherif M, Marrero MB. Janus kinase 2, an early target of alpha 7 nicotinic acetylcholine receptor-mediated neuroprotection against Abeta-(1-42) amyloid. J Biol Chem. 2002;277:44920\u20134.","journal-title":"J Biol Chem"},{"key":"283_CR7","doi-asserted-by":"crossref","first-page":"11224","DOI":"10.1523\/JNEUROSCI.23-35-11224.2003","volume":"23","author":"S Shaw","year":"2003","unstructured":"Shaw S, Bencherif M, Marrero MB. Angiotensin II blocks nicotine-mediated neuroprotection against beta-amyloid (1-42) via activation of the tyrosine phosphatase SHP-1. J Neurosci. 2003;23:11224\u20138.","journal-title":"J Neurosci"},{"issue":"3","key":"283_CR8","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1124\/jpet.109.160861","volume":"332","author":"HK Takahashi","year":"2010","unstructured":"Takahashi HK, Liu K, Wake H, Mori S, Zhang J, Liu R, et al. Effect of nicotine on advanced glycation end product-induced immune response in human monocytes. J Pharmacol Exp Ther. 2010;332(3):1013\u201321.","journal-title":"J Pharmacol Exp Ther"},{"issue":"5","key":"283_CR9","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1097\/01.shk.0000209539.91553.82","volume":"25","author":"D Altavilla","year":"2006","unstructured":"Altavilla D, Guarini S, Bitto A, Mioni AC, Giuliani D, Bigiani A, et al. Activation of the cholinergic anti-inflammatory pathway reduces NF-kappaB activation, blunts TNF-alpha production, and protects againts splanchic artery occlusion shock. Shock. 2006;25(5):500\u20136.","journal-title":"Shock"},{"issue":"1","key":"283_CR10","doi-asserted-by":"crossref","first-page":"401","DOI":"10.4049\/jimmunol.0901808","volume":"184","author":"X Su","year":"2010","unstructured":"Su X, Matthay MA, Malik AB. Requisite role of the cholinergic alpha7 nicotinic acetylcholine receptor pathway in suppressing Gram-negative sepsis-induced acute lung inflammatory injury. J Immunol. 2010;184(1):401\u201310.","journal-title":"J Immunol"}],"container-title":["Pharmaceutical Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11095-010-0283-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11095-010-0283-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11095-010-0283-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,4]],"date-time":"2019-06-04T20:14:48Z","timestamp":1559679288000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11095-010-0283-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,9,22]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2011,2]]}},"alternative-id":["283"],"URL":"https:\/\/doi.org\/10.1007\/s11095-010-0283-7","relation":{},"ISSN":["0724-8741","1573-904X"],"issn-type":[{"value":"0724-8741","type":"print"},{"value":"1573-904X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,9,22]]}}}