{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:46:14Z","timestamp":1786981574905,"version":"build-2736575974"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2012,5,26]],"date-time":"2012-05-26T00:00:00Z","timestamp":1337990400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharm Res"],"published-print":{"date-parts":[[2012,9]]},"DOI":"10.1007\/s11095-012-0778-5","type":"journal-article","created":{"date-parts":[[2012,5,25]],"date-time":"2012-05-25T05:14:20Z","timestamp":1337922860000},"page":"2489-2498","source":"Crossref","is-referenced-by-count":42,"title":["Effect of Compression on Non-isothermal Crystallization Behaviour of Amorphous Indomethacin"],"prefix":"10.1007","volume":"29","author":[{"given":"Zelalem","family":"Ayenew","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amrit","family":"Paudel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Rombaut","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guy","family":"Van den Mooter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2012,5,26]]},"reference":[{"issue":"4","key":"778_CR1","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1023\/A:1007516718048","volume":"17","author":"BC Hancock","year":"2000","unstructured":"Hancock BC, Parks M. What is the true solubility advantage for amorphous pharmaceuticals? Pharm Res. 2000;17(4):397\u2013404.","journal-title":"Pharm Res"},{"issue":"3","key":"778_CR2","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1002\/jps.20557","volume":"95","author":"T Okumura","year":"2006","unstructured":"Okumura T, Ishida M, Takayama K, Otsuka M. Polymorphic transformation of indomethacin under high pressures. J Pharm Sci. 2006;95(3):689\u2013700.","journal-title":"J Pharm Sci"},{"issue":"12","key":"778_CR3","doi-asserted-by":"crossref","first-page":"1700","DOI":"10.1002\/jps.2600831211","volume":"83","author":"M Yoshioka","year":"1994","unstructured":"Yoshioka M, Hancock BC, Zografi G. Crystallization of indomethacin from the amorphous state below and above its glass transition temperature. J Pharm Sci. 1994;83(12):1700\u20135.","journal-title":"J Pharm Sci"},{"issue":"1","key":"778_CR4","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1021\/jp053545u","volume":"110","author":"L Carpentier","year":"2006","unstructured":"Carpentier L, Decressain R, Desprez S, Descamps M. Dynamics of the amorphous and crystalline \u03b1-, \u03b3-phases of indomethacin. J Phys Chem B. 2006;110(1):457\u201364.","journal-title":"J Phys Chem B"},{"issue":"25","key":"778_CR5","doi-asserted-by":"crossref","first-page":"7283","DOI":"10.1021\/jp0700027","volume":"111","author":"S Vyazovkin","year":"2007","unstructured":"Vyazovkin S, Dranca I. Effect of physical aging on nucleation of amorphous indomethacin. J Phys Chem B. 2007;111(25):7283\u20137.","journal-title":"J Phys Chem B"},{"issue":"10","key":"778_CR6","doi-asserted-by":"crossref","first-page":"4446","DOI":"10.1002\/jps.21291","volume":"97","author":"C Bhugra","year":"2008","unstructured":"Bhugra C, Shmeis R, Pikal MJ. Role of mechanical stress in crystallization and relaxation behavior of amorphous indomethacin. J Pharm Sci. 2008;97(10):4446\u201358.","journal-title":"J Pharm Sci"},{"issue":"3","key":"778_CR7","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1021\/js9602711","volume":"86","author":"V Andronis","year":"1997","unstructured":"Andronis V, Yoshioka M, Zografi G. Effects of sorbed water on the crystallization of indomethacin from the amorphous state. J Pharm Sci. 1997;86(3):346\u201351.","journal-title":"J Pharm Sci"},{"issue":"42\u201349","key":"778_CR8","doi-asserted-by":"crossref","first-page":"4480","DOI":"10.1016\/j.jnoncrysol.2006.02.130","volume":"352","author":"S Desprez","year":"2006","unstructured":"Desprez S, Descamps M. Transformations of glassy indomethacin induced by ball-milling. J Non-Cryst Solids. 2006;352(42\u201349):4480\u20135.","journal-title":"J Non-Cryst Solids"},{"issue":"2","key":"778_CR9","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/j.ejpb.2011.10.006","volume":"80","author":"P Karmwar","year":"2012","unstructured":"Karmwar P, Graeser K, Gordon KC, Strachan CJ, Rades T. Effect of different preparation methods on the dissolution behaviour of amorphous indomethacin. Eur J Pharm Biopharm. 2012;80(2):459\u201364.","journal-title":"Eur J Pharm Biopharm"},{"issue":"8","key":"778_CR10","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1002\/jps.1052","volume":"90","author":"G Mooter Van Den","year":"2001","unstructured":"Van Den Mooter G, Craig DQM, Royall PG. Characterization of amorphous ketoconazole using modulated temperature differential scanning calorimetry. J Pharm Sci. 2001;90(8):996\u20131003.","journal-title":"J Pharm Sci"},{"key":"778_CR11","unstructured":"Forster A, Hempenstall J, Rades T. Investigation of drug\/polymer interaction in glass solutions prepared by melt extrusion. Int J Vib Spec. 2001;5(6): http:\/\/www.ijvs.com\/volume5\/edition2\/section3.html accessed on May 4, 2012."},{"issue":"17","key":"778_CR12","doi-asserted-by":"crossref","first-page":"175505","DOI":"10.1103\/PhysRevLett.89.175505","volume":"89","author":"FM Capaldi","year":"2002","unstructured":"Capaldi FM, Boyce MC, Rutledge GC. Enhanced mobility accompanies the active deformation of a glassy amorphous polymer. Phys Rev Lett. 2002;89(17):175505 (1\u20134).","journal-title":"Phys Rev Lett"},{"issue":"1","key":"778_CR13","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.ejpb.2012.01.007","volume":"81","author":"Z Ayenew","year":"2012","unstructured":"Ayenew Z, Paudel A, Van den Mooter G. Can compression induce demixing in amorphous solid dispersions? A case study of naproxen-PVP K25. Eur J Pharm Biopharm. 2012;81(1):207\u201313.","journal-title":"Eur J Pharm Biopharm"},{"issue":"7","key":"778_CR14","doi-asserted-by":"crossref","first-page":"2626","DOI":"10.1021\/ma802041n","volume":"42","author":"F Daver","year":"2009","unstructured":"Daver F, Blake A, Cakmak M. Stages of structural ordering leading to stress induced crystallization of PEEK films: a mechano-optical study on deformation, relaxation and retraction. Macromolecules. 2009;42(7):2626\u201333.","journal-title":"Macromolecules"},{"issue":"12","key":"778_CR15","doi-asserted-by":"crossref","first-page":"4328","DOI":"10.1021\/ma900394n","volume":"42","author":"HN Lee","year":"2009","unstructured":"Lee HN, Riggleman RA, de Pablo JJ, Ediger M. Deformation-induced mobility in polymer glasses during multistep creep experiments and simulations. Macromolecules. 2009;42(12):4328\u201336.","journal-title":"Macromolecules"},{"issue":"014901","key":"778_CR16","first-page":"1","volume":"133","author":"H Lee","year":"2010","unstructured":"Lee H, Ediger MD. Interaction between physical aging, deformation, and segmental mobility in poly(methyl methacrylate) glasses. J Chem Phys. 2010;133(014901):1\u20139.","journal-title":"J Chem Phys"},{"key":"778_CR17","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.ijpharm.2011.01.052","volume":"408","author":"K Imamura","year":"2011","unstructured":"Imamura K, Kagotani R, Nomura M, Tanaka K, Kinugawa K, Nakanishi K. Influence of compression on water sorption, glass transition, and enthalpy relaxation behavior of freeze-dried amorphous sugar matrices. Int J Pharm. 2011;408(1\u20132):76\u201383.","journal-title":"Int J Pharm"},{"issue":"9","key":"778_CR18","doi-asserted-by":"crossref","first-page":"3787","DOI":"10.1002\/jps.22197","volume":"99","author":"JA Baird","year":"2010","unstructured":"Baird JA, Van Eerdenbrugh B, Taylor LS. A classification system to assess the crystallization tendency of organic molecules from undercooled melts. J Pharm Sci. 2010;99(9):3787\u2013806.","journal-title":"J Pharm Sci"},{"issue":"10","key":"778_CR19","doi-asserted-by":"crossref","first-page":"4314","DOI":"10.1248\/cpb.34.4314","volume":"34","author":"E Fukuoka","year":"1986","unstructured":"Fukuoka E, Makita M, Yamamura S. Some physicochemical properties of glassy indomethacin. Chem Pharm Bull. 1986;34(10):4314\u201321.","journal-title":"Chem Pharm Bull"},{"issue":"3","key":"778_CR20","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.ejps.2011.08.010","volume":"44","author":"P Karmwar","year":"2011","unstructured":"Karmwar P, Boetker JP, Graeser KA, Strachan CJ, Rantanen J, Rades T. Investigations on the effect of different cooling rates on the stability of amorphous indomethacin. Eur J Pharm Sci. 2011;44(3):341\u201350.","journal-title":"Eur J Pharm Sci"},{"issue":"37","key":"778_CR21","doi-asserted-by":"crossref","first-page":"12536","DOI":"10.1021\/jp905162r","volume":"113","author":"Z Wojnarowska","year":"2009","unstructured":"Wojnarowska Z, Adrjanowicz K, Wlodarczyk P, Kaminska E, Kaminski K, Grzybowska K, et al. Broadband dielectric relaxation study at ambient and elevated pressure of molecular dynamics of pharmaceutical: indomethacin. J Phys Chem B. 2009;113(37):12536\u201345.","journal-title":"J Phys Chem B"},{"issue":"3","key":"778_CR22","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/S0022-3093(00)00107-1","volume":"271","author":"V Andronis","year":"2000","unstructured":"Andronis V, Zografi G. Crystal nucleation and growth of indomethacin polymorphs from the amorphous state. J Non-Cryst Solids. 2000;271(3):236\u201348.","journal-title":"J Non-Cryst Solids"}],"container-title":["Pharmaceutical Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11095-012-0778-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11095-012-0778-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11095-012-0778-5","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T01:54:23Z","timestamp":1559354063000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11095-012-0778-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,5,26]]},"references-count":22,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2012,9]]}},"alternative-id":["778"],"URL":"https:\/\/doi.org\/10.1007\/s11095-012-0778-5","relation":{},"ISSN":["0724-8741","1573-904X"],"issn-type":[{"value":"0724-8741","type":"print"},{"value":"1573-904X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,5,26]]}}}