{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T01:13:17Z","timestamp":1773277997545,"version":"3.50.1"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2014,2,11]],"date-time":"2014-02-11T00:00:00Z","timestamp":1392076800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Clin Pharm"],"published-print":{"date-parts":[[2014,4]]},"DOI":"10.1007\/s11096-013-9910-9","type":"journal-article","created":{"date-parts":[[2014,2,10]],"date-time":"2014-02-10T07:10:09Z","timestamp":1392016209000},"page":"405-411","source":"Crossref","is-referenced-by-count":15,"title":["Amiodarone-induced thyroid dysfunction in Taiwan: a retrospective cohort study"],"prefix":"10.1007","volume":"36","author":[{"given":"Chun-Jui","family":"Huang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Po-Ju","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing-Wen","family":"Chang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"De-Feng","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shih-Lin","family":"Chang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shih-Ann","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tjin-Shing","family":"Jap","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liang-Yu","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,2,11]]},"reference":[{"key":"9910_CR1","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/S0735-1097(97)00220-9","volume":"30","author":"VR Vorperian","year":"1997","unstructured":"Vorperian VR, Havighurst TC, Miller S, January CT. Adverse effects of low dose amiodarone: a meta-analysis. J Am Coll Cardiol. 1997;30:791\u20138.","journal-title":"J Am Coll Cardiol"},{"key":"9910_CR2","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1111\/j.1365-2265.2008.03350.x","volume":"70","author":"TS Han","year":"2009","unstructured":"Han TS, Williams GR, Vanderpump MP. Benzofuran derivatives and the thyroid. Clin Endocrinol. 2009;70:2\u201313.","journal-title":"Clin Endocrinol"},{"key":"9910_CR3","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1038\/nrendo.2009.225","volume":"6","author":"J Cohen-Lehman","year":"2010","unstructured":"Cohen-Lehman J, Dahl P, Danzi S, Klein I. Effects of amiodarone therapy on thyroid function. Nat Rev Endocrinol. 2010;6:34\u201341.","journal-title":"Nat Rev Endocrinol."},{"key":"9910_CR4","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1093\/qjmed\/hcg158","volume":"96","author":"J Sidhu","year":"2003","unstructured":"Sidhu J, Jenkins D. Men are at increased risk of amiodarone-associated thyrotoxicosis in the UK. QJM. 2003;96:949\u201350.","journal-title":"QJM"},{"key":"9910_CR5","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1590\/S0004-27302005000600010","volume":"49","author":"BD Schaan","year":"2005","unstructured":"Schaan BD, Cunha CP, Francisconi A, Zottis B, Brum G, Bruch RS, et al. Amiodarone-induced thyroid dysfunction in a tertiary center in south Brazil. Arq Bras Endocrinol Metabol. 2005;49:916\u201322.","journal-title":"Arq Bras Endocrinol Metabol."},{"key":"9910_CR6","first-page":"434","volume":"16","author":"KF Lee","year":"2010","unstructured":"Lee KF, Lee KM, Fung TT. Amiodarone-induced thyroid dysfunction in the Hong Kong Chinese population. Hong Kong Med J. 2010;16:434\u20139.","journal-title":"Hong Kong Med J."},{"key":"9910_CR7","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1111\/j.1365-2265.2011.04087.x","volume":"75","author":"S Ahmed","year":"2011","unstructured":"Ahmed S, Van Gelder IC, Wiesfeld AC, Van Veldhuisen DJ, Links TP. Determinants and outcome of amiodarone-associated thyroid dysfunction. Clin Endocrinol. 2011;75:388\u201394.","journal-title":"Clin Endocrinol"},{"key":"9910_CR8","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1016\/j.ijcard.2012.02.015","volume":"167","author":"MN Stan","year":"2013","unstructured":"Stan MN, Ammash NM, Warnes CA, Brennan MD, Thapa P, Nannenga MR, et al. Body mass index and the development of amiodarone-induced thyrotoxicosis in adults with congenital heart disease-A cohort study. Int J Cardiol. 2013;167:821\u20136.","journal-title":"Int J Cardiol"},{"key":"9910_CR9","first-page":"2","volume":"63","author":"I Zosin","year":"2012","unstructured":"Zosin I, Balas M. Amiodarone-induced thyroid dysfunction in an iodine-replete area: epidemiological and clinical data. Endokrynol Pol. 2012;63:2\u20139.","journal-title":"Endokrynol Pol."},{"key":"9910_CR10","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1111\/j.1365-2265.1987.tb00781.x","volume":"26","author":"E Martino","year":"1987","unstructured":"Martino E, Aghini-Lombardi F, Mariotti S, Bartalena L, Lenziardi M, Ceccarelli C, et al. Amiodarone iodine-induced hypothyroidism: risk factors and follow-up in 28 cases. Clin Endocrinol. 1987;26:227\u201337.","journal-title":"Clin Endocrinol"},{"key":"9910_CR11","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/0002-9343(91)90187-3","volume":"91","author":"MD Trip","year":"1991","unstructured":"Trip MD, Wiersinga W, Plomp TA. Incidence, predictability, and pathogenesis of amiodarone-induced thyrotoxicosis and hypothyroidism. Am J Med. 1991;91:507\u201311.","journal-title":"Am J Med"},{"key":"9910_CR12","doi-asserted-by":"crossref","first-page":"533","DOI":"10.2298\/MPNS1112533A","volume":"64","author":"Z Aleksic","year":"2011","unstructured":"Aleksic Z, Aleksic A. Incidence of amiodarone-induced thyroid dysfunction and predictive factors for their occurrence. Med Pregl. 2011;64:533\u20138.","journal-title":"Med Pregl"},{"key":"9910_CR13","doi-asserted-by":"crossref","first-page":"2722","DOI":"10.1001\/archinte.1994.00420230115013","volume":"154","author":"E Martino","year":"1994","unstructured":"Martino E, Aghini-Lombardi F, Bartalena L, Grasso L, Loviselli A, Velluzzi F, et al. Enhanced susceptibility to amiodarone-induced hypothyroidism in patients with thyroid autoimmune disease. Arch Intern Med. 1994;154:2722\u20136.","journal-title":"Arch Intern Med"},{"key":"9910_CR14","doi-asserted-by":"crossref","first-page":"28","DOI":"10.7326\/0003-4819-101-1-28","volume":"101","author":"E Martino","year":"1984","unstructured":"Martino E, Safran M, Aghini-Lombardi F, Rajatanavin R, Lenziardi M, Fay M, et al. Environmental iodine intake and thyroid dysfunction during chronic amiodarone therapy. Ann Intern Med. 1984;101:28\u201334.","journal-title":"Ann Intern Med"},{"key":"9910_CR15","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1161\/01.CIR.100.2.149","volume":"100","author":"SA Thorne","year":"1999","unstructured":"Thorne SA, Barnes I, Cullinan P, Somerville J. Amiodarone-associated thyroid dysfunction: risk factors in adults with congenital heart disease. Circulation. 1999;100:149\u201354.","journal-title":"Circulation"},{"key":"9910_CR16","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1002\/pds.735","volume":"11","author":"ML Bouvy","year":"2002","unstructured":"Bouvy ML, Heerdink ER, Hoes AW, Leufkens HG. Amiodarone-induced thyroid dysfunction associated with cumulative dose. Pharmacoepidemiol Drug Saf. 2002;11:601\u20136.","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"9910_CR17","first-page":"20","volume":"48","author":"HD Lin","year":"1991","unstructured":"Lin HD, Lo JG, Ching KN. Amount of urinary iodine excretion in residents of Taipei City: a hospital-based study. J Chin Med Assoc. 1991;48:20\u20134.","journal-title":"J Chin Med Assoc."},{"key":"9910_CR18","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1007\/s00508-008-1017-2","volume":"120","author":"A Hofmann","year":"2008","unstructured":"Hofmann A, Nawara C, Ofluoglu S, Holzmannhofer J, Strohmer B, Pirich C. Incidence and predictability of amiodarone-induced thyrotoxicosis and hypothyroidism. Wien Klin Wochenschr. 2008;120:493\u20138.","journal-title":"Wien Klin Wochenschr"},{"key":"9910_CR19","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1111\/j.1365-2265.2006.02590.x","volume":"65","author":"LA Diehl","year":"2006","unstructured":"Diehl LA, Romaldini JH, Graf H, Bartalena L, Martino E, Albino CC, et al. Management of amiodarone-induced thyrotoxicosis in Latin America: an electronic survey. Clin Endocrinol. 2006;65:433\u20138.","journal-title":"Clin Endocrinol"},{"key":"9910_CR20","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1111\/j.1365-2265.2008.03268.x","volume":"69","author":"ML Tanda","year":"2008","unstructured":"Tanda ML, Piantanida E, Lai A, Liparulo L, Sassi L, Bogazzi F, et al. Diagnosis and management of amiodarone-induced thyrotoxicosis: similarities and differences between North American and European thyroidologists. Clin Endocrinol. 2008;69:812\u20138.","journal-title":"Clin Endocrinol"},{"key":"9910_CR21","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1111\/j.1365-2265.2004.02119.x","volume":"61","author":"L Bartalena","year":"2004","unstructured":"Bartalena L, Wiersinga WM, Tanda ML, Bogazzi F, Piantanida E, Lai A, et al. Diagnosis and management of amiodarone-induced thyrotoxicosis in Europe: results of an international survey among members of the European Thyroid Association. Clin Endocrinol. 2004;61:494\u2013502.","journal-title":"Clin Endocrinol"},{"key":"9910_CR22","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1089\/105072501300176471","volume":"11","author":"F Bogazzi","year":"2001","unstructured":"Bogazzi F, Bartalena L, Gasperi M, Braverman LE, Martino E. The various effects of amiodarone on thyroid function. Thyroid. 2001;11:511\u20139.","journal-title":"Thyroid."},{"key":"9910_CR23","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1097\/00045391-200607000-00007","volume":"13","author":"V Bongard","year":"2006","unstructured":"Bongard V, Marc D, Philippe V, Jean-Louis M, Maryse LM. Incidence rate of adverse drug reactions during long-term follow-up of patients newly treated with amiodarone. Am J Ther. 2006;13:315\u20139.","journal-title":"Am J Ther"},{"key":"9910_CR24","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1016\/j.amjmed.2007.04.022","volume":"120","author":"EL Batcher","year":"2007","unstructured":"Batcher EL, Tang XC, Singh BN, Singh SN, Reda DJ, Hershman JM, et al. Thyroid function abnormalities during amiodarone therapy for persistent atrial fibrillation. Am J Med. 2007;120:880\u20135.","journal-title":"Am J Med"},{"key":"9910_CR25","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1111\/j.1365-2265.1995.tb01894.x","volume":"43","author":"MP Vanderpump","year":"1995","unstructured":"Vanderpump MP, Tunbridge WM, French JM, Appleton D, Bates D, Clark F, et al. The incidence of thyroid disorders in the community: a twenty-year follow-up of the Whickham Survey. Clin Endocrinol. 1995;43:55\u201368.","journal-title":"Clin Endocrinol"},{"key":"9910_CR26","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1210\/jc.2009-1977","volume":"95","author":"JP Walsh","year":"2010","unstructured":"Walsh JP, Bremner AP, Feddema P, Leedman PJ, Brown SJ, O\u2019Leary P. Thyrotropin and thyroid antibodies as predictors of hypothyroidism: a 13-year, longitudinal study of a community-based cohort using current immunoassay techniques. J Clin Endocrinol Metab. 2010;95:1095\u2013104.","journal-title":"J Clin Endocrinol Metab"},{"key":"9910_CR27","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1210\/jc.2011-1724","volume":"97","author":"BO Asvold","year":"2012","unstructured":"Asvold BO, Vatten LJ, Midthjell K, Bjoro T. Serum TSH within the reference range as a predictor of future hypothyroidism and hyperthyroidism: 11-year follow-up of the HUNT Study in Norway. J Clin Endocrinol Metab. 2012;97:93\u20139.","journal-title":"J Clin Endocrinol Metab"},{"key":"9910_CR28","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.archger.2009.09.004","volume":"51","author":"CC Huang","year":"2010","unstructured":"Huang CC, Chen YC, Chen LK, Hwang SJ, Lin HD. Relationship between age and serum thyrotropin among asymptomatic older people in Taiwan. Arch Gerontol Geriatr. 2010;51:117\u201320.","journal-title":"Arch Gerontol Geriatr"},{"key":"9910_CR29","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0167-4943(03)00080-3","volume":"38","author":"RG Gheri","year":"2004","unstructured":"Gheri RG, Pucci P, Falsetti C, Luisi ML, Cerisano GP, Gheri CF, et al. Clinical, biochemical and therapeutical aspects of amiodarone-induced hypothyroidism (AIH) in geriatric patients with cardiac arrhythmias. Arch Gerontol Geriatr. 2004;38:27\u201336.","journal-title":"Arch Gerontol Geriatr"},{"key":"9910_CR30","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.archger.2011.05.003","volume":"55","author":"M Maselli","year":"2012","unstructured":"Maselli M, Inelmen EM, Giantin V, Manzato E. Hypothyroidism in the elderly: diagnostic pitfalls illustrated by a case report. Arch Gerontol Geriatr. 2012;55:82\u20134.","journal-title":"Arch Gerontol Geriatr"},{"key":"9910_CR31","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.1445-5994.2006.01068.x","volume":"36","author":"C Burgess","year":"2006","unstructured":"Burgess C, Blaikie A, Ingham T, Robinson G, Narasimhan S. Monitoring the use of amiodarone: compliance with guidelines. Intern Med J. 2006;36:289\u201393.","journal-title":"Intern Med J."},{"key":"9910_CR32","doi-asserted-by":"crossref","first-page":"656","DOI":"10.18553\/jmcp.2006.12.8.656","volume":"12","author":"MA Raebel","year":"2006","unstructured":"Raebel MA, Carroll NM, Simon SR, Andrade SE, Feldstein AC, Lafata JE, et al. Liver and thyroid monitoring in ambulatory patients prescribed amiodarone in 10 HMOs. J Manag Care Pharm. 2006;12:656\u201364.","journal-title":"J Manag Care Pharm."}],"container-title":["International Journal of Clinical Pharmacy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11096-013-9910-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11096-013-9910-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11096-013-9910-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,26]],"date-time":"2022-03-26T04:16:40Z","timestamp":1648268200000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11096-013-9910-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,2,11]]},"references-count":32,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,4]]}},"alternative-id":["9910"],"URL":"https:\/\/doi.org\/10.1007\/s11096-013-9910-9","relation":{},"ISSN":["2210-7703","2210-7711"],"issn-type":[{"value":"2210-7703","type":"print"},{"value":"2210-7711","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,2,11]]}}}