{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T14:32:44Z","timestamp":1793111564306,"version":"4.5.0"},"reference-count":12,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2022,11,23]],"date-time":"2022-11-23T00:00:00Z","timestamp":1669161600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,11,23]],"date-time":"2022-11-23T00:00:00Z","timestamp":1669161600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Clin Pharm"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Inappropriate antibiotic prescribing upon hospital discharge has been identified as a significant problem. Despite high rates of antibiotic prescription errors, there is no widely accepted antimicrobial stewardship initiative to prevent such errors.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Aim<\/jats:title>\n                <jats:p>The primary objective of this study was to determine the impact of hospital-based clinical pharmacist discharge prescription review on the appropriateness of antibiotic prescriptions.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Method<\/jats:title>\n                <jats:p>This was an observational study comparing the appropriateness of hospital discharge antibiotic prescriptions between two similar internal medicine services. One cohort of patients was admitted to medicine services where rounding clinical pharmacists performed routine antibiotic discharge assessment, and the comparator cohort was admitted to hospitalist services without routine pharmacist discharge antibiotic review.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Our study included 150 cases per cohort. Baseline characteristics were similar between groups, except for increased age (<jats:italic>p<\/jats:italic>\u2009=\u20090.025) and fewer cases of acute bacterial skin &amp; skin structure infections (<jats:italic>p<\/jats:italic>\u2009=\u20090.001) in the hospitalist cohort. Antibiotic appropriateness was considerably greater in the medicine (pharmacist) group versus hospitalist group [(83% versus 54%, respectively (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.00001)]. The difference in appropriateness was mainly driven by pneumonia and urinary tract infection prescriptions.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Appropriateness of antibiotic prescriptions significantly improved in the setting of pharmacist discharge review. This initiative highlights the important role of clinical pharmacists in outpatient antimicrobial stewardship.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s11096-022-01503-7","type":"journal-article","created":{"date-parts":[[2022,11,24]],"date-time":"2022-11-24T15:18:15Z","timestamp":1669303095000},"page":"769-773","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Impact of clinical pharmacist discharge prescription review on the appropriateness of antibiotic therapy: a retrospective comparison"],"prefix":"10.1007","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6840-1343","authenticated-orcid":false,"given":"Amy","family":"Spigelmyer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catessa","family":"Howard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4223-6391","authenticated-orcid":false,"given":"Ilya","family":"Rybakov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3893-6598","authenticated-orcid":false,"given":"Sheena","family":"Burwell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4318-7165","authenticated-orcid":false,"given":"Douglas","family":"Slain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,11,23]]},"reference":[{"key":"1503_CR1","unstructured":"Centers for disease control and prevention; antibiotic prescribing and Use. Available from: https:\/\/www.cdc.gov\/antibiotic-use\/data\/outpatient-prescribing\/index.html. Accessed 15 Jun 2022."},{"key":"1503_CR2","doi-asserted-by":"publisher","first-page":"e4499","DOI":"10.1093\/cid\/ciaa1372","volume":"73","author":"V Vaughn","year":"2021","unstructured":"Vaughn V, Gandhi T, Chopra V, et al. Antibiotic overuse after hospital discharge: a multi-hospital cohort study. Clin Infect Dis. 2021;73:e4499\u2013506.","journal-title":"Clin Infect Dis"},{"key":"1503_CR3","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1017\/ice.2016.276","volume":"38","author":"S Scarpato","year":"2017","unstructured":"Scarpato S, Timko D, Cluzet V, et al. An evaluation of antibiotic prescribing practices upon hospital discharge. Infect Control Hosp Epidemiol. 2017;38:353\u20135.","journal-title":"Infect Control Hosp Epidemiol"},{"key":"1503_CR4","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1017\/ice.2014.85","volume":"36","author":"N Yogo","year":"2015","unstructured":"Yogo N, Haas M, Knepper B, et al. Antibiotic prescribing at the transition from hospitalization to discharge: a target for antimicrobial stewardship. Infect Control Hosp Epidemiol. 2015;36:474\u20138.","journal-title":"Infect Control Hosp Epidemiol"},{"key":"1503_CR5","first-page":"1308","volume":"60","author":"L Hicks","year":"2015","unstructured":"Hicks L, Bartoces M, Roberts R, et al. US outpatient antibiotic prescribing variation according to geography, patient population, and provider specialty in 2011. Clin Infect Dis. 2015;60:1308\u201316.","journal-title":"Clin Infect Dis"},{"key":"1503_CR6","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1017\/ice.2020.367","volume":"42","author":"L Daniels","year":"2021","unstructured":"Daniels L, Weber D. Interventions to improve antibiotic prescribing at hospital discharge: a systematic review. Infect Control Hosp Epidemiol. 2021;42:96\u20139.","journal-title":"Infect Control Hosp Epidemiol"},{"key":"1503_CR7","doi-asserted-by":"publisher","first-page":"674","DOI":"10.1002\/jac5.1420","volume":"4","author":"M Francis","year":"2021","unstructured":"Francis M, Wai A, Patanwala A. Association between admission medication reconciliation by pharmacists on the accuracy of hospital discharge medication lists. J Am Coll Clin Pharm. 2021;4:674\u20139.","journal-title":"J Am Coll Clin Pharm"},{"key":"1503_CR8","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/j.annemergmed.2012.04.011","volume":"61","author":"J Cesarz","year":"2013","unstructured":"Cesarz J, Steffenhagen A, Svenson J, et al. Emergency department discharge prescription interventions by emergency medicine pharmacists. Ann Emerg Med. 2013;61:209\u201314.","journal-title":"Ann Emerg Med"},{"issue":"1","key":"1503_CR9","first-page":"32","volume":"1","author":"R Sawyer","year":"2016","unstructured":"Sawyer R, Odom J, Jennings J, et al. Discharge medication reconciliation by pharmacists to improve transitions following hospitalization (DEPTH). GHS Proc. 2016;1(1):32\u20137.","journal-title":"GHS Proc"},{"key":"1503_CR10","doi-asserted-by":"publisher","first-page":"5055","DOI":"10.1310\/hpj5006-505","volume":"50","author":"J Sebaaly","year":"2015","unstructured":"Sebaaly J, Parsons L, Pilch N, et al. Clinical and financial impact of pharmacist involvement in discharge medication reconciliation at an academic medical center: a prospective pilot study. Hosp Pharm. 2015;50:5055\u201313.","journal-title":"Hosp Pharm"},{"key":"1503_CR11","doi-asserted-by":"publisher","first-page":"1027","DOI":"10.2165\/11538310-000000000-00000","volume":"33","author":"D Abdel-Qader","year":"2010","unstructured":"Abdel-Qader D, Harper L, Cantrill J, et al. Pharmacists\u2019 interventions in prescribing errors at hospital discharge. Drug Saf. 2010;33:1027\u201344.","journal-title":"Drug Saf"},{"key":"1503_CR12","doi-asserted-by":"publisher","first-page":"1091","DOI":"10.1093\/cid\/ciy1054","volume":"69","author":"D Yahav","year":"2019","unstructured":"Yahav D, Franceschini E, Koppel F, et al. Seven versus 14 days of antibiotic therapy for uncomplicated Gram-negative bacteremia: a noninferiority randomized controlled trial. Clin Infect Dis. 2019;69:1091\u20138.","journal-title":"Clin Infect Dis"}],"container-title":["International Journal of Clinical Pharmacy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11096-022-01503-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11096-022-01503-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11096-022-01503-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,8]],"date-time":"2023-06-08T11:15:27Z","timestamp":1686222927000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11096-022-01503-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,23]]},"references-count":12,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["1503"],"URL":"https:\/\/doi.org\/10.1007\/s11096-022-01503-7","relation":{},"ISSN":["2210-7703","2210-7711"],"issn-type":[{"value":"2210-7703","type":"print"},{"value":"2210-7711","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11,23]]},"assertion":[{"value":"7 July 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 October 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 November 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors have no conflicts of interest to declare that are relevant to the content of this article.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}}]}}