{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T22:50:57Z","timestamp":1761519057512},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2013,1,19]],"date-time":"2013-01-19T00:00:00Z","timestamp":1358553600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pituitary"],"published-print":{"date-parts":[[2014,2]]},"DOI":"10.1007\/s11102-013-0462-8","type":"journal-article","created":{"date-parts":[[2013,1,18]],"date-time":"2013-01-18T10:08:29Z","timestamp":1358503709000},"page":"30-37","source":"Crossref","is-referenced-by-count":11,"title":["Frequency of multiple endocrine neoplasia type 1 in a group of patients with pituitary adenoma: genetic study and familial screening"],"prefix":"10.1007","volume":"17","author":[{"given":"V. S.","family":"Nunes","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. L.","family":"Souza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Perone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. J.","family":"Conde","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. R.","family":"Nogueira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2013,1,19]]},"reference":[{"issue":"4","key":"462_CR1","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S1043-2760(00)00372-6","volume":"12","author":"DH Schussheim","year":"2001","unstructured":"Schussheim DH, Skarulis MC, Agarwal SK, Simonds WF, Burns AL, Spiegel AM, Marx SJ (2001) Multiple endocrine neoplasia type 1: new clinical and basic findings. Trends Endocrinol Metab 12(4):173\u2013178","journal-title":"Trends Endocrinol Metab"},{"issue":"1","key":"462_CR2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0889-8529(18)30112-9","volume":"23","author":"B Skogseid","year":"1994","unstructured":"Skogseid B, Rastad J, Oberg K (1994) Multiple endocrine neoplasia type 1. Clinical features and screening. Endocrinol Metab Clin North Am 23(1):1\u201318","journal-title":"Endocrinol Metab Clin North Am"},{"issue":"3","key":"462_CR3","first-page":"205","volume":"4","author":"BW Scheithauer","year":"1987","unstructured":"Scheithauer BW, Laws ER Jr, Kovacs K, Horvath E, Randall RV, Carney JA (1987) Pituitary adenomas of the multiple endocrine neoplasia type I syndrome. Semin Diagn Pathol 4(3):205\u2013211","journal-title":"Semin Diagn Pathol"},{"issue":"12","key":"462_CR4","doi-asserted-by":"crossref","first-page":"5658","DOI":"10.1210\/jcem.86.12.8070","volume":"86","author":"ML Brandi","year":"2001","unstructured":"Brandi ML, Gagel RF, Angeli A, Bilezikian JP, Beck-Peccoz P, Bordi C, Conte-Devolx B, Falchetti A, Gheri RG, Libroia A et al (2001) Guidelines for diagnosis and therapy of MEN type 1 and type 2. J Clin Endocrinol Metab 86(12):5658\u20135671","journal-title":"J Clin Endocrinol Metab"},{"issue":"3","key":"462_CR5","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1158\/1078-0432.CCR-0938-3","volume":"10","author":"B Asgharian","year":"2004","unstructured":"Asgharian B, Chen YJ, Patronas NJ, Peghini PL, Reynolds JC, Vortmeyer A, Zhuang Z, Venzon DJ, Gibril F, Jensen RT (2004) Meningiomas may be a component tumor of multiple endocrine neoplasia type 1. Clin Cancer Res 10(3):869\u2013880","journal-title":"Clin Cancer Res"},{"issue":"2","key":"462_CR6","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1210\/jcem-31-2-180","volume":"31","author":"JH Lawrence","year":"1970","unstructured":"Lawrence JH, Tobias CA, Linfoot JA, Born JL, Lyman JT, Chong CY, Manougian E, Wei WC (1970) Successful treatment of acromegaly: metabolic and clinical studies in 145 patients. J Clin Endocrinol Metab 31(2):180\u2013198","journal-title":"J Clin Endocrinol Metab"},{"issue":"4","key":"462_CR7","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1111\/j.1365-2265.1987.tb00805.x","volume":"26","author":"JD Nabarro","year":"1987","unstructured":"Nabarro JD (1987) Acromegaly. Clin Endocrinol (Oxf) 26(4):481\u2013512","journal-title":"Clin Endocrinol (Oxf)"},{"issue":"6","key":"462_CR8","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1111\/j.1365-2265.1990.tb03914.x","volume":"33","author":"HO Andersen","year":"1990","unstructured":"Andersen HO, Jorgensen PE, Bardram L, Hilsted L (1990) Screening for multiple endocrine neoplasia type 1 in patients with recognized pituitary adenoma. Clin Endocrinol (Oxf) 33(6):771\u2013775","journal-title":"Clin Endocrinol (Oxf)"},{"key":"462_CR9","volume-title":"A laboratory manual","year":"1989","unstructured":"Sambrook JFE, Maniatis T (eds) (1989) A laboratory manual. Cold Spring Harbor Laboratory Press, New York"},{"issue":"3","key":"462_CR10","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1530\/EJE-08-0153","volume":"159","author":"DM Lourenco Jr","year":"2008","unstructured":"Lourenco DM Jr, Toledo RA, Mackowiak II, Coutinho FL, Cavalcanti MG, Correia-Deur JE, Montenegro F, Siqueira SA, Margarido LC, Machado MC et al (2008) Multiple endocrine neoplasia type 1 in Brazil: MEN1 founding mutation, clinical features, and bone mineral density profile. Eur J Endocrinol 159(3):259\u2013274","journal-title":"Eur J Endocrinol"},{"issue":"5","key":"462_CR11","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1590\/S0004-27302005000500014","volume":"49","author":"AO Hoff","year":"2005","unstructured":"Hoff AO, Hauache OM (2005) Multiple endocrine neoplasia type 1 (MEN 1): clinical, biochemical and molecular diagnosis and treatment of the associated disturbances. Arq Bras Endocrinol Metabol 49(5):735\u2013746","journal-title":"Arq Bras Endocrinol Metabol"},{"issue":"5","key":"462_CR12","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1046\/j.1365-2265.1997.3311122.x","volume":"47","author":"S Corbetta","year":"1997","unstructured":"Corbetta S, Pizzocaro A, Peracchi M, Beck-Peccoz P, Faglia G, Spada A (1997) Multiple endocrine neoplasia type 1 in patients with recognized pituitary tumours of different types. Clin Endocrinol (Oxf) 47(5):507\u2013512","journal-title":"Clin Endocrinol (Oxf)"},{"key":"462_CR13","unstructured":"Marx SJ, Agarwal SK, Kester MB, Heppner C, Kim YS, Skarulis MC, James LA, Goldsmith PK, Saggar SK, Park SY et al (1999) Multiple endocrine neoplasia type 1: clinical and genetic features of the hereditary endocrine neoplasias. Recent Prog Horm Res 54:397\u2013438; discussion 438\u2013399"},{"issue":"4","key":"462_CR14","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/0002-9343(87)90008-8","volume":"82","author":"L Benson","year":"1987","unstructured":"Benson L, Ljunghall S, Akerstrom G, Oberg K (1987) Hyperparathyroidism presenting as the first lesion in multiple endocrine neoplasia type 1. Am J Med 82(4):731\u2013737","journal-title":"Am J Med"},{"issue":"3","key":"462_CR15","doi-asserted-by":"crossref","first-page":"383","DOI":"10.3109\/02841868909111211","volume":"28","author":"K Oberg","year":"1989","unstructured":"Oberg K, Skogseid B, Eriksson B (1989) Multiple endocrine neoplasia type 1 (MEN-1). Clinical, biochemical and genetical investigations. Acta Oncol 28(3):383\u2013387","journal-title":"Acta Oncol"},{"issue":"4","key":"462_CR16","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1210\/edrv-8-4-391","volume":"8","author":"ML Brandi","year":"1987","unstructured":"Brandi ML, Marx SJ, Aurbach GD, Fitzpatrick LA (1987) Familial multiple endocrine neoplasia type I: a new look at pathophysiology. Endocr Rev 8(4):391\u2013405","journal-title":"Endocr Rev"},{"issue":"2","key":"462_CR17","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1210\/jcem.87.2.8145","volume":"87","author":"B Verges","year":"2002","unstructured":"Verges B, Boureille F, Goudet P, Murat A, Beckers A, Sassolas G, Cougard P, Chambe B, Montvernay C, Calender A (2002) Pituitary disease in MEN type 1 (MEN1): data from the France-Belgium MEN1 multicenter study. J Clin Endocrinol Metab 87(2):457\u2013465","journal-title":"J Clin Endocrinol Metab"},{"issue":"4","key":"462_CR18","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1097\/PAS.0b013e31815ade45","volume":"32","author":"J Trouillas","year":"2008","unstructured":"Trouillas J, Labat-Moleur F, Sturm N, Kujas M, Heymann MF, Figarella-Branger D, Patey M, Mazucca M, Decullier E, Verges B et al (2008) Pituitary tumors and hyperplasia in multiple endocrine neoplasia type 1 syndrome (MEN1): a case-control study in a series of 77 patients versus 2509 non-MEN1 patients. Am J Surg Pathol 32(4):534\u2013543","journal-title":"Am J Surg Pathol"},{"issue":"3","key":"462_CR19","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/S0889-8529(05)70150-X","volume":"29","author":"RV Thakker","year":"2000","unstructured":"Thakker RV (2000) Multiple endocrine neoplasia type 1. Endocrinol Metab Clin North Am 29(3):541\u2013567","journal-title":"Endocrinol Metab Clin North Am"},{"issue":"4","key":"462_CR20","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1046\/j.1365-2265.2000.00966.x","volume":"52","author":"N Hai","year":"2000","unstructured":"Hai N, Aoki N, Shimatsu A, Mori T, Kosugi S (2000) Clinical features of multiple endocrine neoplasia type 1 (MEN1) phenocopy without germline MEN1 gene mutations: analysis of 20 Japanese sporadic cases with MEN1. Clin Endocrinol (Oxf) 52(4):509\u2013518","journal-title":"Clin Endocrinol (Oxf)"},{"issue":"6","key":"462_CR21","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1046\/j.1365-2362.2000.00664.x","volume":"30","author":"JF Roijers","year":"2000","unstructured":"Roijers JF, de Wit MJ, van der Luijt RB (2000) Ploos van Amstel HK, Hoppener JW, Lips CJ: Criteria for mutation analysis in MEN 1-suspected patients: MEN 1 case-finding. Eur J Clin Invest 30(6):487\u2013492","journal-title":"Eur J Clin Invest"},{"issue":"2","key":"462_CR22","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1097\/01.GIM.0000153663.62300.F8","volume":"7","author":"RD Klein","year":"2005","unstructured":"Klein RD, Salih S, Bessoni J, Bale AE (2005) Clinical testing for multiple endocrine neoplasia type 1 in a DNA diagnostic laboratory. Genet Med 7(2):131\u2013138","journal-title":"Genet Med"},{"issue":"2","key":"462_CR23","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1111\/j.1365-2265.2005.02190.x","volume":"62","author":"S Ellard","year":"2005","unstructured":"Ellard S, Hattersley AT, Brewer CM, Vaidya B (2005) Detection of an MEN1 gene mutation depends on clinical features and supports current referral criteria for diagnostic molecular genetic testing. Clin Endocrinol (Oxf) 62(2):169\u2013175","journal-title":"Clin Endocrinol (Oxf)"},{"issue":"2","key":"462_CR24","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1046\/j.1365-2265.2000.01032.x","volume":"53","author":"JR Burgess","year":"2000","unstructured":"Burgess JR, Nord B, David R, Greenaway TM, Parameswaran V, Larsson C, Shepherd JJ, Teh BT (2000) Phenotype and phenocopy: the relationship between genotype and clinical phenotype in a single large family with multiple endocrine neoplasia type 1 (MEN 1). Clin Endocrinol (Oxf) 53(2):205\u2013211","journal-title":"Clin Endocrinol (Oxf)"},{"issue":"8","key":"462_CR25","doi-asserted-by":"crossref","first-page":"3321","DOI":"10.1210\/jc.2006-2843","volume":"92","author":"M Georgitsi","year":"2007","unstructured":"Georgitsi M, Raitila A, Karhu A, van der Luijt RB, Aalfs CM, Sane T, Vierimaa O, Makinen MJ, Tuppurainen K, Paschke R et al (2007) Germline CDKN1B\/p27Kip1 mutation in multiple endocrine neoplasia. J Clin Endocrinol Metab 92(8):3321\u20133325","journal-title":"J Clin Endocrinol Metab"},{"issue":"11","key":"462_CR26","first-page":"3048","volume":"62","author":"A Fritz","year":"2002","unstructured":"Fritz A, Walch A, Piotrowska K, Rosemann M, Schaffer E, Weber K, Timper A, Wildner G, Graw J, Hofler H et al (2002) Recessive transmission of a multiple endocrine neoplasia syndrome in the rat. Cancer Res 62(11):3048\u20133051","journal-title":"Cancer Res"},{"issue":"6","key":"462_CR27","doi-asserted-by":"crossref","first-page":"2390","DOI":"10.1210\/jc.2007-2611","volume":"93","author":"CA Leontiou","year":"2008","unstructured":"Leontiou CA, Gueorguiev M, van der Spuy J, Quinton R, Lolli F, Hassan S, Chahal HS, Igreja SC, Jordan S, Rowe J et al (2008) The role of the aryl hydrocarbon receptor-interacting protein gene in familial and sporadic pituitary adenomas. J Clin Endocrinol Metab 93(6):2390\u20132401","journal-title":"J Clin Endocrinol Metab"},{"issue":"5","key":"462_CR28","doi-asserted-by":"crossref","first-page":"1934","DOI":"10.1210\/jc.2006-2394","volume":"92","author":"RA Toledo","year":"2007","unstructured":"Toledo RA, Lourenco DM, Liberman B Jr, Cunha-Neto MB, Cavalcanti MG, Moyses CB, Toledo SP, Dahia PL (2007) Germline mutation in the aryl hydrocarbon receptor interacting protein gene in familial somatotropinoma. J Clin Endocrinol Metab 92(5):1934\u20131937","journal-title":"J Clin Endocrinol Metab"},{"issue":"2","key":"462_CR29","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1111\/j.1365-2265.2008.03379.x","volume":"70","author":"S Igreja","year":"2009","unstructured":"Igreja S, Chahal HS, Akker SA, Gueorguiev M, Popovic V, Damjanovic S, Burman P, Wass JA, Quinton R, Grossman AB et al (2009) Assessment of p27 (cyclin-dependent kinase inhibitor 1B) and aryl hydrocarbon receptor-interacting protein (AIP) genes in multiple endocrine neoplasia (MEN1) syndrome patients without any detectable MEN1 gene mutations. Clin Endocrinol (Oxf) 70(2):259\u2013264","journal-title":"Clin Endocrinol (Oxf)"},{"issue":"1","key":"462_CR30","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1002\/humu.20605","volume":"29","author":"MC Lemos","year":"2008","unstructured":"Lemos MC, Thakker RV (2008) Multiple endocrine neoplasia type 1 (MEN1): analysis of 1336 mutations reported in the first decade following identification of the gene. Hum Mutat 29(1):22\u201332","journal-title":"Hum Mutat"},{"issue":"5","key":"462_CR31","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1590\/S0004-27302007000500009","volume":"51","author":"AP Rocha","year":"2007","unstructured":"Rocha AP, Magalhaes PK, Maia AL, Maciel LM (2007) Genetic polymorphisms: implications in the pathogenesis of medullary thyroid carcinoma. Arq Bras Endocrinol Metabol 51(5):723\u2013730","journal-title":"Arq Bras Endocrinol Metabol"}],"container-title":["Pituitary"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11102-013-0462-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11102-013-0462-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11102-013-0462-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,8]],"date-time":"2019-07-08T13:26:58Z","timestamp":1562592418000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11102-013-0462-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1,19]]},"references-count":31,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,2]]}},"alternative-id":["462"],"URL":"https:\/\/doi.org\/10.1007\/s11102-013-0462-8","relation":{},"ISSN":["1386-341X","1573-7403"],"issn-type":[{"value":"1386-341X","type":"print"},{"value":"1573-7403","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,1,19]]}}}