{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T05:44:11Z","timestamp":1793166251835,"version":"4.5.0"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2024,9,25]],"date-time":"2024-09-25T00:00:00Z","timestamp":1727222400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,9,25]],"date-time":"2024-09-25T00:00:00Z","timestamp":1727222400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100017590","name":"Universit\u00e4tsklinikum Essen","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100017590","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pituitary"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Objective<\/jats:title>\n                <jats:p>A patient-centered approach to the management of acromegaly includes disease activity control, shared decision-making and identification of comorbidities. The Acromegaly Disease Activity Tool (ACRODAT<jats:sup>\u00ae<\/jats:sup>) is intended to assist physicians in providing such holistic management. The present study investigated this claim using the simulated person (SP) approach.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>We studied patient-doctor interaction via online video consultation in a randomized prospective study design with SPs trained to simulate a specific acromegaly profile. We analyzed the proportion of conversation time devoted to health content and the specific acromegaly and comorbidity relevant categories mentioned in the conversation. We collected physicians\u2019 feedback on the usefulness of ACRODAT<jats:sup>\u00ae<\/jats:sup>, SPs subjective perception of the quality of the conversation and compared consultations with and without ACRODAT<jats:sup>\u00ae<\/jats:sup> using a qualitative approach.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The sample (<jats:italic>N<\/jats:italic>\u2009=\u200930) consisted of endocrinologists treating patients with acromegaly in Germany. For SP-physician interactions (<jats:italic>N<\/jats:italic>\u2009=\u200960), the proportion of time spent on conversation content (e.g. IGF-I, quality of life) was distributed according to the focus of the patient profile. Comorbidities were less well identified than the need for a change in therapy. Only 18.3% of the SPs were actively asked to participate in the decision-making process. ACRODAT<jats:sup>\u00ae<\/jats:sup> did not lead to any significant differences in the course of the discussion.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Shared decision-making was underrepresented in this SP-physician interaction in acromegaly management. Physicians adapted the content of the discussion to the SP\u2019s needs, but did not adequately address comorbidities. According to the analysis criteria used, ACRODAT<jats:sup>\u00ae<\/jats:sup> did not contribute to a more holistic patient management in the present study.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s11102-024-01460-6","type":"journal-article","created":{"date-parts":[[2024,9,25]],"date-time":"2024-09-25T06:05:29Z","timestamp":1727244329000},"page":"545-554","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Shared decision-making and detection of comorbidities in an online acromegaly consultation with and without the Acromegaly Disease Activity Tool ACRODAT\u00ae using the simulated person approach"],"prefix":"10.1007","volume":"27","author":[{"given":"Anna Lena","family":"Friedel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-0615-5752","authenticated-orcid":false,"given":"Lisa","family":"Schock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonja","family":"Siegel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelika Hiroko","family":"Fritz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Unger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birgit","family":"Harbeck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philipp","family":"Dammann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilonka","family":"Kreitschmann-Andermahr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,9,25]]},"reference":[{"issue":"11","key":"1460_CR1","doi-asserted-by":"publisher","first-page":"804","DOI":"10.1016\/s2213-8587(22)00244-3","volume":"10","author":"M Fleseriu","year":"2022","unstructured":"Fleseriu M et al (2022) Acromegaly: pathogenesis, diagnosis, and management. 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SoS received research support and\/or travel grants and\/or consultation fees from IPSEN Pharma GmbH Germany, Advanz Pharma GmbH, Pfizer Pharma GmbH Germany and Pfizer Inc. BH received research support and\/or travel grants and\/or lecture or advisory board honoraria from Recordati Rare Diseases GmbH, Pfizer Pharma GmbH Germany and Alexion Pharma Germany GmbH. LS, ALF, AHF and PD declare to have no conflict of interest in relation to the content of this article.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}