{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T05:37:27Z","timestamp":1776922647459,"version":"3.51.2"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2025,8,30]],"date-time":"2025-08-30T00:00:00Z","timestamp":1756512000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,8,30]],"date-time":"2025-08-30T00:00:00Z","timestamp":1756512000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pituitary"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1007\/s11102-025-01567-4","type":"journal-article","created":{"date-parts":[[2025,8,30]],"date-time":"2025-08-30T05:48:49Z","timestamp":1756532929000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Urinary incontinence as a novel and underrecognized clinical manifestation of prolactinoma in women"],"prefix":"10.1007","volume":"28","author":[{"given":"Emre","family":"Hep\u015fen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatih","family":"\u00c7anakl\u0131","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Halil","family":"Duranta\u015f","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bur\u00e7ak","family":"Cavnar Helvac\u0131","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kubilay","family":"Sar\u0131kaya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erman","family":"\u00c7akal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sema","family":"Hep\u015fen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,8,30]]},"reference":[{"key":"1567_CR1","doi-asserted-by":"publisher","first-page":"2400","DOI":"10.1210\/clinem\/dgad174","volume":"108","author":"RS Auriemma","year":"2023","unstructured":"Auriemma RS, Pirchio R, Pivonello C et al (2023) Approach to the patient with prolactinoma. J Clin Endocrinol Metab 108:2400\u20132423. https:\/\/doi.org\/10.1210\/clinem\/dgad174","journal-title":"J Clin Endocrinol Metab"},{"key":"1567_CR2","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/s11102-005-5079-0","volume":"8","author":"A Ciccarelli","year":"2005","unstructured":"Ciccarelli A, Daly AF, Beckers A (2005) The epidemiology of prolactinomas. Pituitary 8:3\u20136. https:\/\/doi.org\/10.1007\/s11102-005-5079-0","journal-title":"Pituitary"},{"key":"1567_CR3","doi-asserted-by":"publisher","first-page":"2729","DOI":"10.1210\/jc.2009-0177","volume":"94","author":"M Kars","year":"2009","unstructured":"Kars M, Souverein PC, Herings RMC et al (2009) Estimated age- and sex-specific incidence and prevalence of dopamine agonist-treated hyperprolactinemia. J Clin Endocrinol Metab 94:2729\u20132734. https:\/\/doi.org\/10.1210\/jc.2009-0177","journal-title":"J Clin Endocrinol Metab"},{"key":"1567_CR4","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1159\/000497746","volume":"109","author":"L Vroonen","year":"2019","unstructured":"Vroonen L, Daly AF, Beckers A (2019) Epidemiology and management challenges in prolactinomas. Neuroendocrinology 109:20\u201327. https:\/\/doi.org\/10.1159\/000497746","journal-title":"Neuroendocrinology"},{"key":"1567_CR5","doi-asserted-by":"publisher","first-page":"1386","DOI":"10.1001\/jama.2023.5444","volume":"329","author":"NA Tritos","year":"2023","unstructured":"Tritos NA, Miller KK (2023) Diagnosis and management of pituitary adenomas. JAMA 329:1386. https:\/\/doi.org\/10.1001\/jama.2023.5444","journal-title":"JAMA"},{"key":"1567_CR6","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1080\/17446651.2018.1434412","volume":"13","author":"RS Auriemma","year":"2018","unstructured":"Auriemma RS, De Alcubierre D, Pirchio R et al (2018) The effects of hyperprolactinemia and its control on metabolic diseases. Expert Rev Endocrinol Metab 13:99\u2013106. https:\/\/doi.org\/10.1080\/17446651.2018.1434412","journal-title":"Expert Rev Endocrinol Metab"},{"key":"1567_CR7","doi-asserted-by":"publisher","first-page":"594370","DOI":"10.3389\/fendo.2020.594370","volume":"11","author":"RS Auriemma","year":"2020","unstructured":"Auriemma RS, Del Vecchio G, Scairati R et al (2020) The interplay between prolactin and reproductive system: focus on uterine pathophysiology. Front Endocrinol 11:594370. https:\/\/doi.org\/10.3389\/fendo.2020.594370","journal-title":"Front Endocrinol"},{"key":"1567_CR8","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1002\/jcp.1041480116","volume":"148","author":"MD Sauro","year":"1991","unstructured":"Sauro MD, Zorn NE (1991) Prolactin induces proliferation of vascular smooth muscle cells through a protein kinase c-dependent mechanism. J Cell Physiol 148:133\u2013138. https:\/\/doi.org\/10.1002\/jcp.1041480116","journal-title":"J Cell Physiol"},{"key":"1567_CR9","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1002\/nau.10052","volume":"21","author":"P Abrams","year":"2002","unstructured":"Abrams P, Cardozo L, Fall M et al (2002) The standardisation of terminology of lower urinary tract function: report from the standardisation sub-committee of the international continence society. Neurourol Urodyn 21:167\u2013178. https:\/\/doi.org\/10.1002\/nau.10052","journal-title":"Neurourol Urodyn"},{"key":"1567_CR10","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.eururo.2022.01.045","volume":"82","author":"AK Nambiar","year":"2022","unstructured":"Nambiar AK, Arlandis S, B\u00f8 K et al (2022) European association of urology guidelines on the diagnosis and management of female non-neurogenic lower urinary tract symptoms. Part 1: diagnostics, overactive bladder, stress urinary incontinence, and mixed urinary incontinence. Eur Urol 82:49\u201359. https:\/\/doi.org\/10.1016\/j.eururo.2022.01.045","journal-title":"Eur Urol"},{"key":"1567_CR11","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1002\/nau.20798","volume":"29","author":"BT Haylen","year":"2010","unstructured":"Haylen BT, de Ridder D, Freeman RM et al (2010) An international urogynecological association (IUGA)\/international continence society (ICS) joint report on the terminology for female pelvic floor dysfunction. Neurourol Urodyn 29:4\u201320. https:\/\/doi.org\/10.1002\/nau.20798","journal-title":"Neurourol Urodyn"},{"key":"1567_CR12","first-page":"280","volume":"57","author":"SSR Solano","year":"2012","unstructured":"Solano SSR, Rodr\u00edguez CSMM (2012) Plasma prolactin levels in women with and without overactive bladder. Med Asoc Med Hosp ABC 57:280\u2013283","journal-title":"Med Asoc Med Hosp ABC"},{"issue":"3","key":"1567_CR13","first-page":"332","volume":"30","author":"B \u00c7entinel","year":"2004","unstructured":"\u00c7entinel B (2004) Et al., the validation study of ICIQ-SF Turkish version ICIQ-SF T\u00fcrk\u00e7e Versiyonu Validasyon (ge\u00e7erlilik) \u00c7ali\u015fmasi. Turk Uroloji Dergisi 30(3):332\u2013338","journal-title":"Turk Uroloji Dergisi"},{"key":"1567_CR14","doi-asserted-by":"publisher","DOI":"10.1111\/jne.13385","author":"CM Banks","year":"2024","unstructured":"Banks CM, Trott JF, Hovey RC (2024) The prolactin receptor: a cross-species comparison of gene structure, transcriptional regulation, tissue\u2010specificity, and genetic variation. J Neuroendocrinol. https:\/\/doi.org\/10.1111\/jne.13385","journal-title":"J Neuroendocrinol"},{"key":"1567_CR15","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1038\/s41574-019-0194-6","volume":"15","author":"V Bernard","year":"2019","unstructured":"Bernard V, Young J, Binart N (2019) Prolactin \u2014 a pleiotropic factor in health and disease. Nat Rev Endocrinol 15:356\u2013365. https:\/\/doi.org\/10.1038\/s41574-019-0194-6","journal-title":"Nat Rev Endocrinol"},{"key":"1567_CR16","doi-asserted-by":"publisher","first-page":"1787","DOI":"10.1016\/0024-3205(89)90566-3","volume":"44","author":"MD Sauro","year":"1989","unstructured":"Sauro MD, Buckley AR, Russell DH, Fitzpatrick DF (1989) Prolactin stimulation of protein kinase C activity in rat aortic smooth muscle. Life Sci 44:1787\u20131792. https:\/\/doi.org\/10.1016\/0024-3205(89)90566-3","journal-title":"Life Sci"},{"key":"1567_CR17","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1152\/physrev.00038.2003","volume":"84","author":"K-E Andersson","year":"2004","unstructured":"Andersson K-E, Arner A (2004) Urinary bladder contraction and relaxation: physiology and pathophysiology. Physiol Rev 84:935\u2013986. https:\/\/doi.org\/10.1152\/physrev.00038.2003","journal-title":"Physiol Rev"},{"key":"1567_CR18","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1016\/S0020-7292(03)00220-0","volume":"82","author":"VA Minassian","year":"2003","unstructured":"Minassian VA, Drutz HP, Al-Badr A (2003) Urinary incontinence as a worldwide problem. Int J Gynecol Obstet 82:327\u2013338. https:\/\/doi.org\/10.1016\/S0020-7292(03)00220-0","journal-title":"Int J Gynecol Obstet"},{"key":"1567_CR19","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1016\/j.eururo.2024.12.017","volume":"87","author":"L Moris","year":"2025","unstructured":"Moris L, Heesakkers J, Nitti V et al (2025) Prevalence, diagnosis, and management of stress urinary incontinence in women: a collaborative review. Eur Urol 87:292\u2013301. https:\/\/doi.org\/10.1016\/j.eururo.2024.12.017","journal-title":"Eur Urol"},{"issue":"Suppl 3","key":"1567_CR20","first-page":"S3","volume":"6","author":"KM Luber","year":"2004","unstructured":"Luber KM (2004) The definition, prevalence, and risk factors for stress urinary incontinence. Rev Urol 6(Suppl 3):S3-9","journal-title":"Rev Urol"},{"key":"1567_CR21","doi-asserted-by":"publisher","first-page":"1203","DOI":"10.1016\/j.urology.2008.11.009","volume":"73","author":"AV Sarma","year":"2009","unstructured":"Sarma AV, Kanaya A, Nyberg LM et al (2009) Risk factors for urinary incontinence among women with type 1 diabetes: findings from the epidemiology of diabetes interventions and complications study. Urology 73:1203\u20131209. https:\/\/doi.org\/10.1016\/j.urology.2008.11.009","journal-title":"Urology"},{"key":"1567_CR22","doi-asserted-by":"publisher","first-page":"2031","DOI":"10.1007\/s00192-022-05206-5","volume":"33","author":"K Erta\u015f","year":"2022","unstructured":"Erta\u015f K, Y\u0131ld\u0131z H, Demir M et al (2022) Effect of combined use of tolterodine and continuous positive airway pressure vs continuous positive airway pressure only treatment on overactive bladder symptoms in women with moderate-to-severe obstructive sleep apnea syndrome: a randomized clinical tri. Int Urogynecol J 33:2031\u20132036. https:\/\/doi.org\/10.1007\/s00192-022-05206-5","journal-title":"Int Urogynecol J"},{"key":"1567_CR23","volume-title":"Incontinence","year":"2017","unstructured":"Abrams P, Cardozo L, Wagg A, Wein A (eds) (2017) Incontinence, 6th edn. International Continence Society, Bristol (UK)","edition":"6"},{"key":"1567_CR24","doi-asserted-by":"publisher","first-page":"448","DOI":"10.1111\/inr.12048","volume":"60","author":"T Basak","year":"2013","unstructured":"Basak T, Kok G, Guvenc G (2013) Prevalence, risk factors and quality of life in Turkish women with urinary incontinence: a synthesis of the literature. Int Nurs Rev 60:448\u2013460. https:\/\/doi.org\/10.1111\/inr.12048","journal-title":"Int Nurs Rev"},{"key":"1567_CR25","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/S1471-7697(03)00051-0","volume":"3","author":"MCLCL Parsons","year":"2003","unstructured":"Parsons MCLCL (2003) The classification of urinary incontinence. Rev Gynaecol Pract 3:57\u201364","journal-title":"Rev Gynaecol Pract"},{"key":"1567_CR26","unstructured":"C. T (2015) Risk Fakt\u00f6rleri, \u00d6nleyici Tedbirler. In: Onur R, Bayrak \u00d6, editors. \u0130stanbul: T\u00fcrk \u00dcroloji Akademisi \/ Nobel T\u0131p Kitabevleri. In: \u00dcriner \u0130nkontinans Tan\u0131 ve Tedavi. pp 77\u201383"},{"key":"1567_CR27","doi-asserted-by":"publisher","first-page":"e42996","DOI":"10.1097\/MD.0000000000042996","volume":"104","author":"W Jing","year":"2025","unstructured":"Jing W, Wei C, Huang Y et al (2025) Relationship between the weight-adjusted-waist index and urinary incontinence in women: a cross-sectional study of NHANES 2007 to 2020. Medicine (Baltimore) 104:e42996. https:\/\/doi.org\/10.1097\/MD.0000000000042996","journal-title":"Medicine (Baltimore)"},{"key":"1567_CR28","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1097\/JU.0000000000003761","volume":"211","author":"C-W Fwu","year":"2024","unstructured":"Fwu C-W, Schulman IH, Lawrence JM et al (2024) Association of obesity, metabolic syndrome, and diabetes with urinary incontinence and chronic kidney disease: analysis of the National health and nutrition examination survey, 2003\u20132020. J Urol 211:124\u2013133. https:\/\/doi.org\/10.1097\/JU.0000000000003761","journal-title":"J Urol"}],"container-title":["Pituitary"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11102-025-01567-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11102-025-01567-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11102-025-01567-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T19:00:14Z","timestamp":1762282814000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11102-025-01567-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,30]]},"references-count":28,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["1567"],"URL":"https:\/\/doi.org\/10.1007\/s11102-025-01567-4","relation":{},"ISSN":["1386-341X","1573-7403"],"issn-type":[{"value":"1386-341X","type":"print"},{"value":"1573-7403","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,30]]},"assertion":[{"value":"7 August 2025","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 August 2025","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was performed in line with the principles of the Declaration of Helsinki. Approval was granted by \u201cScientific Research Assessment and Ethics Committee of Ankara Etlik City Hospital\u201d (Date: 13\/05\/2025 No: AE\u015eH-BADEK2-2025-095).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from participants.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"The authors declare they have no financial interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Financial interests"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"96"}}