{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T12:18:11Z","timestamp":1779279491305,"version":"3.51.4"},"reference-count":6,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100003196","name":"Ministero della Salute","doi-asserted-by":"publisher","award":["Ricerca Corrente"],"award-info":[{"award-number":["Ricerca Corrente"]}],"id":[{"id":"10.13039\/501100003196","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pituitary"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1007\/s11102-026-01668-8","type":"journal-article","created":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T14:42:24Z","timestamp":1775054544000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Persistent remission after steroidogenesis inhibitor discontinuation in Cushing disease: a case series"],"prefix":"10.1007","volume":"29","author":[{"given":"Alessandra","family":"Mangone","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisa","family":"Sala","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giulia","family":"Carosi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giulia Del","family":"Sindaco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberta","family":"Mungari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arianna","family":"Cremaschi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iulia","family":"Petria","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giacomo","family":"Noschese","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Veronica","family":"Lotito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanna","family":"Mantovani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emanuele","family":"Ferrante","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,4,1]]},"reference":[{"issue":"fasc 5","key":"1668_CR1","doi-asserted-by":"publisher","first-page":"1526","DOI":"10.1210\/jc.2008-0125","volume":"93","author":"LK Nieman","year":"2008","unstructured":"Nieman LK et al (2008) The diagnosis of Cushing\u2019s syndrome: An endocrine society clinical practice guideline. J Clin Endocrinol Metab 93(fasc 5):1526\u20131540. https:\/\/doi.org\/10.1210\/jc.2008-0125","journal-title":"J Clin Endocrinol Metab"},{"key":"1668_CR2","doi-asserted-by":"publisher","unstructured":"Fleseriu M et al (2021) \u00abConsensus on diagnosis and management of Cushing\u2019s disease: a guideline update.\u00bb, Lancet Diabetes Endocrinol., vol. 9, fasc. 12, pp. 847\u2013875, dic. https:\/\/doi.org\/10.1016\/S2213-8587(21)00235-7","DOI":"10.1016\/S2213-8587(21)00235-7"},{"key":"1668_CR3","doi-asserted-by":"publisher","unstructured":"Castinetti F, Amodru V, Brue eT (2023) \u00abOsilodrostat in Cushing\u2019s disease: The risk of delayed adrenal insufficiency should be carefully monitored.\u00bb, Clin. Endocrinol. (Oxf.), vol. 98, fasc. 4, pp. 629\u2013630, apr. https:\/\/doi.org\/10.1111\/cen.14551","DOI":"10.1111\/cen.14551"},{"key":"1668_CR4","doi-asserted-by":"publisher","unstructured":"Ferriere A, Salenave S, Puerto M, Young J, Tabarin eA (2024) \u00abProlonged adrenal insufficiency following discontinuation of osilodrostat treatment for intense hypercortisolism.\u00bb, Eur. J. Endocrinol., vol. 190, fasc. 1, pp. L1\u2013L3, gen. https:\/\/doi.org\/10.1093\/ejendo\/lvad167","DOI":"10.1093\/ejendo\/lvad167"},{"key":"1668_CR5","doi-asserted-by":"publisher","unstructured":"Poirier J, Bonnet-Serrano F, Thomeret L, Bouys L, Bertherat eJ (2023) \u00abProlonged adrenocortical blockade following discontinuation of Osilodrostat\u00bb. Eur J Endocrinol 188 fasc. 6, pp. K29\u2013K32, giu. https:\/\/doi.org\/10.1093\/ejendo\/lvad060","DOI":"10.1093\/ejendo\/lvad060"},{"key":"1668_CR6","doi-asserted-by":"publisher","unstructured":"Varlamov EV, Park BJ, Fleseriu eM (2025) \u00abOsilodrostat-associated Adrenal Gland Shrinkage: a Case Series of Patients with ACTH-Dependent Cushing\u2019s Syndrome.\u00bb, J. Clin. Endocrinol. Metab., p. dgaf552, ott. https:\/\/doi.org\/10.1210\/clinem\/dgaf552","DOI":"10.1210\/clinem\/dgaf552"}],"container-title":["Pituitary"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11102-026-01668-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11102-026-01668-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11102-026-01668-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T12:02:05Z","timestamp":1779278525000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11102-026-01668-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":6,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["1668"],"URL":"https:\/\/doi.org\/10.1007\/s11102-026-01668-8","relation":{},"ISSN":["1386-341X","1573-7403"],"issn-type":[{"value":"1386-341X","type":"print"},{"value":"1573-7403","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"18 February 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 March 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 April 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research reported.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"68"}}