{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T18:46:16Z","timestamp":1782413176033,"version":"3.54.5"},"reference-count":40,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T00:00:00Z","timestamp":1776643200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T00:00:00Z","timestamp":1776643200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pituitary"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1007\/s11102-026-01675-9","type":"journal-article","created":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T11:36:53Z","timestamp":1776685013000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of granulation pattern on surgical and long-term outcomes in Cushing\u2019s disease: a comparative study of DGCT and SGCT"],"prefix":"10.1007","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2226-4958","authenticated-orcid":false,"given":"Isabella","family":"Nasi-Kordhishti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirko","family":"Hladik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Behling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9168-6209","authenticated-orcid":false,"given":"Jens","family":"Schittenhelm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7249-8077","authenticated-orcid":false,"given":"J\u00fcrgen","family":"Honegger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,4,20]]},"reference":[{"issue":"1","key":"1675_CR1","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1007\/s12022-022-09703-7","volume":"33","author":"SL Asa","year":"2022","unstructured":"Asa SL, Mete O, Perry A, Osamura RY (2022) Overview of the 2022 WHO Classification of Pituitary Tumors. Endocr Pathol 33(1):6\u201326. https:\/\/doi.org\/10.1007\/s12022-022-09703-7[published Online First: 20220315]","journal-title":"Endocr Pathol"},{"issue":"12","key":"1675_CR2","doi-asserted-by":"publisher","first-page":"847","DOI":"10.1016\/S2213-8587(21)00235-7","volume":"9","author":"M Fleseriu","year":"2021","unstructured":"Fleseriu M, Auchus R, Bancos I et al (2021) Consensus on diagnosis and management of Cushing\u2019s disease: a guideline update. Lancet Diabetes Endocrinol 9(12):847\u2013875. https:\/\/doi.org\/10.1016\/S2213-8587(21)00235-7[published Online First: 20211020]","journal-title":"Lancet Diabetes Endocrinol"},{"issue":"5","key":"1675_CR3","doi-asserted-by":"publisher","first-page":"1526","DOI":"10.1210\/jc.2008-0125","volume":"93","author":"LK Nieman","year":"2008","unstructured":"Nieman LK, Biller BM, Findling JW et al (2008) The diagnosis of Cushing\u2019s syndrome: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab 93(5):1526\u20131540. https:\/\/doi.org\/10.1210\/jc.2008-0125[published Online First: 20080311]","journal-title":"J Clin Endocrinol Metab"},{"issue":"5","key":"1675_CR4","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1007\/s11102-018-0904-4","volume":"21","author":"J Honegger","year":"2018","unstructured":"Honegger J, Grimm F (2018) The experience with transsphenoidal surgery and its importance to outcomes. Pituitary 21(5):545\u2013555. https:\/\/doi.org\/10.1007\/s11102-018-0904-4","journal-title":"Pituitary"},{"issue":"5","key":"1675_CR5","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1007\/s11102-020-01066-8","volume":"23","author":"A Stroud","year":"2020","unstructured":"Stroud A, Dhaliwal P, Alvarado R et al (2020) Outcomes of pituitary surgery for Cushing\u2019s disease: a systematic review and meta-analysis. Pituitary 23(5):595\u2013609. https:\/\/doi.org\/10.1007\/s11102-020-01066-8","journal-title":"Pituitary"},{"issue":"4","key":"1675_CR6","doi-asserted-by":"publisher","first-page":"C5","DOI":"10.1530\/ERC-17-0004","volume":"24","author":"SL Asa","year":"2017","unstructured":"Asa SL, Casar-Borota O, Chanson P et al (2017) From pituitary adenoma to pituitary neuroendocrine tumor (PitNET): an International Pituitary Pathology Club proposal. Endocr Relat Cancer 24(4):C5\u2013C8. https:\/\/doi.org\/10.1530\/ERC-17-0004","journal-title":"Endocr Relat Cancer"},{"key":"1675_CR7","unstructured":"WHO Classification of Tumours: Endocrine and Neuroendocrine Tumours. 5th ed, (2025)"},{"issue":"1","key":"1675_CR8","doi-asserted-by":"publisher","first-page":"9","DOI":"10.5146\/tjpath.2018.01434","volume":"35","author":"SC Dogansen","year":"2019","unstructured":"Dogansen SC, Bilgic B, Yalin GY, Tanrikulu S, Yarman S (2019) Clinical Significance of Granulation Pattern in Corticotroph Pituitary Adenomas. Turk Patoloji Derg 35(1):9\u201314. https:\/\/doi.org\/10.5146\/tjpath.2018.01434","journal-title":"Turk Patoloji Derg"},{"issue":"5","key":"1675_CR9","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1007\/s00292-024-01319-4","volume":"45","author":"J Klein","year":"2024","unstructured":"Klein J, Saeger K, Saeger W (2024) [Quantification of Ki-67 in PitNET (pituitary neuroendocrine tumors)\/adenomas]. Pathologie (Heidelb) 45(5):339\u2013343. https:\/\/doi.org\/10.1007\/s00292-024-01319-4[published Online First: 20240711]","journal-title":"Pathologie (Heidelb)"},{"issue":"Suppl 1","key":"1675_CR10","doi-asserted-by":"publisher","first-page":"i10","DOI":"10.1093\/noajnl\/vdae145","volume":"7","author":"SL Asa","year":"2025","unstructured":"Asa SL, Ezzat S, Mete O (2025) Clinical integration and application of the 2022 WHO pituitary tumor classification. Neurooncol Adv 7(Suppl 1):i10\u2013i16. https:\/\/doi.org\/10.1093\/noajnl\/vdae145[published Online First: 20250102]","journal-title":"Neurooncol Adv"},{"issue":"6","key":"1675_CR11","doi-asserted-by":"publisher","first-page":"849","DOI":"10.1016\/s0092-8674(01)00282-3","volume":"104","author":"B Lamolet","year":"2001","unstructured":"Lamolet B, Pulichino AM, Lamonerie T et al (2001) A pituitary cell-restricted T box factor, Tpit, activates POMC transcription in cooperation with Pitx homeoproteins. Cell 104(6):849\u2013859. https:\/\/doi.org\/10.1016\/s0092-8674(01)00282-3","journal-title":"Cell"},{"issue":"4","key":"1675_CR12","doi-asserted-by":"publisher","first-page":"675","DOI":"10.1007\/s00401-017-1768-9","volume":"134","author":"E Sjostedt","year":"2017","unstructured":"Sjostedt E, Bollerslev J, Mulder J, Lindskog C, Ponten F, Casar-Borota O (2017) A specific antibody to detect transcription factor T-Pit: a reliable marker of corticotroph cell differentiation and a tool to improve the classification of pituitary neuroendocrine tumours. Acta Neuropathol 134(4):675\u2013677. https:\/\/doi.org\/10.1007\/s00401-017-1768-9[published Online First: 20170819]","journal-title":"Acta Neuropathol"},{"issue":"1","key":"1675_CR13","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1007\/s12022-018-9563-2","volume":"30","author":"R Hasanov","year":"2019","unstructured":"Hasanov R, Aydogan BI, Kiremitci S, Erden E, Gullu S (2019) The Prognostic Roles of the Ki-67 Proliferation Index, P53 Expression, Mitotic Index, and Radiological Tumor Invasion in Pituitary Adenomas. Endocr Pathol 30(1):49\u201355. https:\/\/doi.org\/10.1007\/s12022-018-9563-2","journal-title":"Endocr Pathol"},{"issue":"4","key":"1675_CR14","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1016\/j.aace.2022.04.003","volume":"8","author":"T Liu","year":"2022","unstructured":"Liu T, Rossiter JP, Houlden RL, Awad S (2022) Sparsely Granulated Corticotroph Pituitary Macroadenoma Presenting With Pituitary Apoplexy Resulting in Remission of Hypercortisolism. AACE Clin Case Rep 8(4):166\u2013170. https:\/\/doi.org\/10.1016\/j.aace.2022.04.003[published Online First: 20220408]","journal-title":"AACE Clin Case Rep"},{"issue":"1","key":"1675_CR15","first-page":"320","volume":"12","author":"C Petry","year":"2019","unstructured":"Petry C, Poli JHZ, de Azevedo Dossin I et al (2019) Evaluation of the potential of the Ki67 index to predict tumor evolution in patients with pituitary adenoma. Int J Clin Exp Pathol 12(1):320\u2013326 [published Online First: 20190101]","journal-title":"Int J Clin Exp Pathol"},{"issue":"3","key":"1675_CR16","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1007\/s12022-024-09819-y","volume":"35","author":"ET Durmus","year":"2024","unstructured":"Durmus ET, Kefeli M, Mete O et al (2024) Granulation Patterns of Functional Corticotroph Tumors Correlate with Tumor Size, Proliferative Activity, T2 Intensity-to-White Matter Ratio, and Postsurgical Early Biochemical Remission. Endocr Pathol 35(3):185\u2013193. https:\/\/doi.org\/10.1007\/s12022-024-09819-y[published Online First: 20240724]","journal-title":"Endocr Pathol"},{"key":"1675_CR17","doi-asserted-by":"publisher","first-page":"672178","DOI":"10.3389\/fendo.2021.672178","volume":"12","author":"B Rak","year":"2021","unstructured":"Rak B, Maksymowicz M, Pekul M, Zielinski G, Clinical (2021) Biological, Radiological Pathological and Immediate Post-Operative Remission of Sparsely and Densely Granulated Corticotroph Pituitary Tumors: A Retrospective Study of a Cohort of 277 Patients With Cushing\u2019s Disease. Front Endocrinol (Lausanne) 12:672178. https:\/\/doi.org\/10.3389\/fendo.2021.672178[published Online First: 20210531]","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"12","key":"1675_CR18","doi-asserted-by":"publisher","first-page":"1340","DOI":"10.1016\/j.amjmed.2005.01.059","volume":"118","author":"LK Nieman","year":"2005","unstructured":"Nieman LK, Ilias I (2005) Evaluation and treatment of Cushing\u2019s syndrome. Am J Med 118(12):1340\u20131346. https:\/\/doi.org\/10.1016\/j.amjmed.2005.01.059","journal-title":"Am J Med"},{"issue":"4","key":"1675_CR19","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1530\/EJE-15-1226","volume":"174","author":"P Witek","year":"2016","unstructured":"Witek P, Zielinski G, Szamotulska K, Maksymowicz M, Kaminski G (2016) Clinicopathological predictive factors in the early remission of corticotroph pituitary macroadenomas in a tertiary referral centre. Eur J Endocrinol 174(4):539\u2013549. https:\/\/doi.org\/10.1530\/EJE-15-1226[published Online First: 20160125]","journal-title":"Eur J Endocrinol"},{"issue":"4","key":"1675_CR20","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1111\/j.1750-3639.2012.00599.x","volume":"22","author":"O Mete","year":"2012","unstructured":"Mete O, Asa SL (2012) Clinicopathological correlations in pituitary adenomas. Brain Pathol 22(4):443\u2013453. https:\/\/doi.org\/10.1111\/j.1750-3639.2012.00599.x","journal-title":"Brain Pathol"},{"issue":"12","key":"1675_CR21","doi-asserted-by":"publisher","first-page":"5593","DOI":"10.1210\/jc.2003-030871","volume":"88","author":"G Arnaldi","year":"2003","unstructured":"Arnaldi G, Angeli A, Atkinson AB et al (2003) Diagnosis and complications of Cushing\u2019s syndrome: a consensus statement. J Clin Endocrinol Metab 88(12):5593\u20135602. https:\/\/doi.org\/10.1210\/jc.2003-030871","journal-title":"J Clin Endocrinol Metab"},{"issue":"4","key":"1675_CR22","doi-asserted-by":"publisher","first-page":"357","DOI":"10.5114\/fn.2020.102438","volume":"58","author":"P Witek","year":"2020","unstructured":"Witek P, Maksymowicz M, Szamotulska K et al (2020) MGMT expression in pituitary corticotroph adenomas and its relationship to clinical, pathological, and ultrastructural parameters in patients with Cushing\u2019s disease. Folia Neuropathol 58(4):357\u2013364. https:\/\/doi.org\/10.5114\/fn.2020.102438","journal-title":"Folia Neuropathol"},{"issue":"6","key":"1675_CR23","doi-asserted-by":"publisher","first-page":"658","DOI":"10.1016\/j.ando.2016.02.004","volume":"77","author":"X Zheng","year":"2016","unstructured":"Zheng X, Li S, Zhang W, Zang Z, Hu J, Yang H (2016) Current biomarkers of invasive sporadic pituitary adenomas. Ann Endocrinol (Paris) 77(6):658\u2013667. https:\/\/doi.org\/10.1016\/j.ando.2016.02.004[published Online First: 20160919]","journal-title":"Ann Endocrinol (Paris)"},{"issue":"3","key":"1675_CR24","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1017\/s0317167100002614","volume":"30","author":"SJ Hentschel","year":"2003","unstructured":"Hentschel SJ, McCutcheon l E, Moore W, Durity FA (2003) P53 and MIB-1 immunohistochemistry as predictors of the clinical behavior of nonfunctioning pituitary adenomas. Can J Neurol Sci 30(3):215\u2013219. https:\/\/doi.org\/10.1017\/s0317167100002614","journal-title":"Can J Neurol Sci"},{"issue":"3","key":"1675_CR25","doi-asserted-by":"publisher","first-page":"502","DOI":"10.1080\/13102818.2014.932510","volume":"28","author":"A Hadzhiyanev","year":"2014","unstructured":"Hadzhiyanev A, Ivanova R, Nachev E et al (2014) Evaluation of prognostic utility of MIB-1 and p53 expression in pituitary adenomas: correlations with clinical behaviour and follow-up results. Biotechnol Biotechnol Equip 28(3):502\u2013507 [published Online First: 20140822]","journal-title":"Biotechnol Biotechnol Equip"},{"issue":"3","key":"1675_CR26","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1007\/s11102-013-0500-6","volume":"17","author":"S Chiloiro","year":"2014","unstructured":"Chiloiro S, Bianchi A, Doglietto F et al (2014) Radically resected pituitary adenomas: prognostic role of Ki 67 labeling index in a monocentric retrospective series and literature review. Pituitary 17(3):267\u2013276. https:\/\/doi.org\/10.1007\/s11102-013-0500-6","journal-title":"Pituitary"},{"issue":"1","key":"1675_CR27","doi-asserted-by":"publisher","first-page":"G1","DOI":"10.1530\/EJE-17-0796","volume":"178","author":"G Raverot","year":"2018","unstructured":"Raverot G, Burman P, McCormack A et al (2018) European Society of Endocrinology Clinical Practice Guidelines for the management of aggressive pituitary tumours and carcinomas. Eur J Endocrinol 178(1):G1\u2013G24. https:\/\/doi.org\/10.1530\/EJE-17-0796[published Online First: 20171018]","journal-title":"Eur J Endocrinol"},{"issue":"2","key":"1675_CR28","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1007\/s12022-019-9568-5","volume":"30","author":"OM Alshaikh","year":"2019","unstructured":"Alshaikh OM, Asa SL, Mete O, Ezzat S (2019) An Institutional Experience of Tumor Progression to Pituitary Carcinoma in a 15-Year Cohort of 1055 Consecutive Pituitary Neuroendocrine Tumors. Endocr Pathol 30(2):118\u2013127. https:\/\/doi.org\/10.1007\/s12022-019-9568-5","journal-title":"Endocr Pathol"},{"issue":"3","key":"1675_CR29","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1007\/s12022-017-9498-z","volume":"28","author":"O Mete","year":"2017","unstructured":"Mete O, Lopes MB (2017) Overview of the 2017 WHO Classification of Pituitary Tumors. Endocr Pathol 28(3):228\u2013243. https:\/\/doi.org\/10.1007\/s12022-017-9498-z","journal-title":"Endocr Pathol"},{"issue":"2","key":"1675_CR30","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1007\/s12022-016-9418-7","volume":"27","author":"W Saeger","year":"2016","unstructured":"Saeger W, Honegger J, Theodoropoulou M et al (2016) Clinical Impact of the Current WHO Classification of Pituitary Adenomas. Endocr Pathol 27(2):104\u2013114. https:\/\/doi.org\/10.1007\/s12022-016-9418-7","journal-title":"Endocr Pathol"},{"issue":"2","key":"1675_CR31","doi-asserted-by":"publisher","first-page":"101514","DOI":"10.1016\/j.beem.2021.101514","volume":"35","author":"ML Gheorghiu","year":"2021","unstructured":"Gheorghiu ML (2021) Updates in the outcomes of radiation therapy for Cushing\u2019s disease. Best Pract Res Clin Endocrinol Metab 35(2):101514. https:\/\/doi.org\/10.1016\/j.beem.2021.101514[published Online First: 20210310]","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"issue":"2","key":"1675_CR32","doi-asserted-by":"publisher","first-page":"121","DOI":"10.3857\/roj.2016.01683","volume":"34","author":"MY Kim","year":"2016","unstructured":"Kim MY, Kim JH, Oh YK, Kim E (2016) Long-term outcomes of surgery and radiotherapy for secreting and non-secreting pituitary adenoma. Radiat Oncol J 34(2):121\u2013127. https:\/\/doi.org\/10.3857\/roj.2016.01683[published Online First: 20160617]","journal-title":"Radiat Oncol J"},{"issue":"3","key":"1675_CR33","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1023\/a:1023365200437","volume":"5","author":"AS Mahmoud-Ahmed","year":"2002","unstructured":"Mahmoud-Ahmed AS, Suh JH (2002) Radiation therapy for Cushing\u2019s disease: a review. Pituitary 5(3):175\u2013180. https:\/\/doi.org\/10.1023\/a:1023365200437","journal-title":"Pituitary"},{"issue":"1","key":"1675_CR34","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1111\/j.1365-2265.2011.04163.x","volume":"76","author":"SL Fougner","year":"2012","unstructured":"Fougner SL, Casar-Borota O, Heck A, Berg JP, Bollerslev J (2012) Adenoma granulation pattern correlates with clinical variables and effect of somatostatin analogue treatment in a large series of patients with acromegaly. Clin Endocrinol (Oxf) 76(1):96\u2013102. https:\/\/doi.org\/10.1111\/j.1365-2265.2011.04163.x","journal-title":"Clin Endocrinol (Oxf)"},{"issue":"4","key":"1675_CR35","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1530\/EJE-12-0864","volume":"168","author":"S Larkin","year":"2013","unstructured":"Larkin S, Reddy R, Karavitaki N, Cudlip S, Wass J, Ansorge O (2013) Granulation pattern, but not GSP or GHR mutation, is associated with clinical characteristics in somatostatin-naive patients with somatotroph adenomas. Eur J Endocrinol 168(4):491\u2013499. https:\/\/doi.org\/10.1530\/EJE-12-0864[published Online First: 20130315]","journal-title":"Eur J Endocrinol"},{"issue":"2","key":"1675_CR36","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1007\/s11102-017-0858-y","volume":"21","author":"F Langlois","year":"2018","unstructured":"Langlois F, Woltjer R, Cetas JS, Fleseriu M (2018) Silent somatotroph pituitary adenomas: an update. Pituitary 21(2):194\u2013202. https:\/\/doi.org\/10.1007\/s11102-017-0858-y","journal-title":"Pituitary"},{"issue":"1","key":"1675_CR37","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1038\/ng.3166","volume":"47","author":"M Reincke","year":"2015","unstructured":"Reincke M, Sbiera S, Hayakawa A et al (2015) Mutations in the deubiquitinase gene USP8 cause Cushing\u2019s disease. Nat Genet 47(1):31\u201338. https:\/\/doi.org\/10.1038\/ng.3166[published Online First: 20141208]","journal-title":"Nat Genet"},{"issue":"6","key":"1675_CR38","doi-asserted-by":"publisher","first-page":"S41","DOI":"10.1093\/ejendo\/lvaf097","volume":"192","author":"LG Perez-Rivas","year":"2025","unstructured":"Perez-Rivas LG, von Selzam V, Sharma P, Reincke M, Theodoropoulou M (2025) Prevalence and clinical associations of USP8 variants in corticotroph tumours: a systematic review and aggregate data meta-analysis of 2171 cases. Eur J Endocrinol 192(6):S41\u2013S52. https:\/\/doi.org\/10.1093\/ejendo\/lvaf097","journal-title":"Eur J Endocrinol"},{"key":"1675_CR39","doi-asserted-by":"publisher","unstructured":"Mossakowska BJ, Rusetska N, Konopinski R et al (2022) The Expression of Cell Cycle-Related Genes in USP8-Mutated Corticotroph Neuroendocrine Pituitary Tumors and Their Possible Role in Cell Cycle-Targeting Treatment. Cancers (Basel) 14(22). https:\/\/doi.org\/10.3390\/cancers14225594[published Online First: 20221114]","DOI":"10.3390\/cancers14225594"},{"key":"1675_CR40","doi-asserted-by":"publisher","unstructured":"Zhang Q, Cai Y, Liu Y et al Risk of recurrence after successful surgery for Cushing\u2019s disease and association with USP8 genotype and tumour size: an international, retrospective, longitudinal cohort study. Lancet Diabetes Endocrinol 2026 https:\/\/doi.org\/10.1016\/S2213-8587(25)00396-1 [published Online First: 20260302].","DOI":"10.1016\/S2213-8587(25)00396-1"}],"container-title":["Pituitary"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11102-026-01675-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11102-026-01675-9","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11102-026-01675-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T17:49:16Z","timestamp":1782409756000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11102-026-01675-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,20]]},"references-count":40,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["1675"],"URL":"https:\/\/doi.org\/10.1007\/s11102-026-01675-9","relation":{},"ISSN":["1386-341X","1573-7403"],"issn-type":[{"value":"1386-341X","type":"print"},{"value":"1573-7403","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,20]]},"assertion":[{"value":"22 February 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 April 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 April 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This retrospective study was approved by the ethics committee of the Eberhard-Karls-University T\u00fcbingen (registration no.050\/2022BO2). All procedures were performed in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"73"}}