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Using a longitudinal, cluster randomized controlled trial (RCT), this study examines whether the <jats:italic>Dating Matters<\/jats:italic> comprehensive prevention model, implemented in middle school, prevented TDV and negative relationship behaviors and promoted positive relationship behaviors in high school (9th\u201311th grades), when compared with a standard of care intervention. <jats:italic>Dating Matters<\/jats:italic> includes programs for sixth to eighth grade youth and their parents, training for school staff, a youth communications program, and policy and data activities implemented in the community. Self-report survey data were collected from students in 46 middle schools that were randomly assigned to condition within site. Students completed two surveys (fall and spring) in each middle school grade and a single survey in the spring of each high school grade. This study examined self-reported TDV perpetration and victimization, use of negative conflict resolution strategies, and positive relationship skills in the high school follow-up. While varying patterns emerged, latent panel models demonstrated significant program effects for all outcomes. <jats:italic>Dating Matters<\/jats:italic> students reported 19% reduced risk for TDV perpetration, 24% reduced risk for TDV victimization, 7% reduced risk for use of negative conflict strategies, and 3% more use of positive relationship skills, on average across time and cohort, than standard of care students. On average, <jats:italic>Dating Matters<\/jats:italic>, implemented in middle school, continued to be more effective at reducing TDV perpetration, TDV victimization, and use of negative conflict resolution strategies in high school than an evidence-based comparison program.<\/jats:p><jats:p>Trial Registration: clinicaltrials.gov Identifier: <jats:underline>NCT01672541.<\/jats:underline><\/jats:p>","DOI":"10.1007\/s11121-024-01648-z","type":"journal-article","created":{"date-parts":[[2024,3,8]],"date-time":"2024-03-08T20:02:14Z","timestamp":1709928134000},"page":"603-615","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["High School Follow-Up of the Dating Matters\u00ae RCT: Effects on Teen Dating Violence and Relationship Behaviors"],"prefix":"10.1007","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9605-3163","authenticated-orcid":false,"given":"Phyllis Holditch","family":"Niolon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lianne F.","family":"Estefan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"DeGue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vi D.","family":"Le","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison J.","family":"Tracy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colleen","family":"Ray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Bontempo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Todd D.","family":"Little","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alana M.","family":"Vivolo-Kantor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natasha","family":"Latzman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce","family":"Taylor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andra","family":"Tharp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,3,8]]},"reference":[{"key":"1648_CR1","doi-asserted-by":"crossref","unstructured":"Basile, K. 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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}},{"value":"The study used active parental consent in three sites and passive parental permission in one site for study participation and youth completed informed assent before participating in the surveys.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed Consent"}},{"value":"None of the authors have conflicts of interest or financial disclosures. All CDC authors worked for the funding organization during the majority of their participation on the project. Dr. Taylor was funded by CDC through a contract to assist with research design and collect all data (Contract #200-211-40998. Statisticians were funded through a staffing contract (Tracy) and IPAs (Little, Bontempo).","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"The findings and conclusions of this report are those of the authors and do not necessarily represent the views or position of the Centers for Disease Control and Prevention.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclaimer"}}]}}