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It is recommended as a superfood to improve general health. However, its role in elite sport has not been studied in detail so far. Therefore, the objective of the study was to assess the effect of regular use of acerola on parameters of the immune system, oxidative stress, and metabolism in elite athletes. The study was carried out in 22 elite endurance athletes (mean age\u2009=\u200924.4\u2009\u00b1\u20094 years; M:F ratio\u2009=\u20091.75), who were supplemented with acerola pulp at a dose of 300\u00a0g\/day for 3 weeks. Detailed laboratory studies, including analyses of biochemical, hematological, and immunological parameters, were carried out in all subjects before and after acerola supplementation. Acerola supplementation did not change any tested parameters of oxidative stress but decreased serum immunoglobulin concentrations and some inflammatory markers. Simultaneously, acerola significantly decreased serum glucose, urea, and liver enzymes ALT and AST, suggesting its role in modulating metabolic flexibility. Acerola supplementation appears to play a beneficial role in elite endurance sports by improving low-grade inflammatory status and metabolic flexibility. Long-term, larger studies are needed to confirm current data and the possible impact on sports performance, as well as to assess any side effects of chronic use.<\/jats:p>","DOI":"10.1007\/s11130-025-01434-4","type":"journal-article","created":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T07:32:04Z","timestamp":1763710324000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The Effect of Acerola Intake on Metabolic and Immunological Parameters in Elite Athletes"],"prefix":"10.1007","volume":"80","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5318-0151","authenticated-orcid":false,"given":"Libor","family":"V\u00edtek","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jana","family":"Haj\u0161lov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milo\u0161","family":"B\u00e1tovsk\u00fd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jana","family":"Woronyczov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helena","family":"Posov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miroslava","family":"Zelenkov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaroslav","family":"Piln\u00fd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Kalousov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,11,21]]},"reference":[{"key":"1434_CR1","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1271\/bbb.69.280","volume":"69","author":"T Hanamura","year":"2005","unstructured":"Hanamura T, Hagiwara T, Kawagishi H (2005) Structural and functional characterization of polyphenols isolated from acerola (Malpighia emarginata DC.) fruit. 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