{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T10:48:15Z","timestamp":1780570095004,"version":"3.54.1"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2020,3,6]],"date-time":"2020-03-06T00:00:00Z","timestamp":1583452800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2020,3,6]],"date-time":"2020-03-06T00:00:00Z","timestamp":1583452800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Qual Life Res"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n<jats:title>Objective<\/jats:title>\n<jats:p>Using data from the nationwide, cross-sectional KiGGS (German Health Interview and Examination Survey for Children and Adolescents) study, we investigated whether hormonal contraception in adolescents aged 15 to 17\u00a0years was linked to health-related quality of life and mental health problems.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>Study participants had undergone standardized recordings of blood pressure and measurements of serum 25-hydroxyvitamin D [25(OH)D]. Quality of life was assessed by self- and parent-rated KINDL-R questionnaires, whereas mental health problems were screened by means of the Strengths and Difficulties Questionnaire (SDQ).<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>Self-rated quality of life was similar between users (<jats:italic>n<\/jats:italic>\u2009=\u2009522) and non-users (<jats:italic>n<\/jats:italic>\u2009=\u20091173, 69.2%) of oral contraceptives (69.2\u2009\u00b1\u200911.2 vs. 69.2\u2009\u00b1\u200911.0, <jats:italic>p<\/jats:italic>\u2009=\u20090.943), as was the parent-rated version (72.9\u2009\u00b1\u200910.6 vs. 72.9\u2009\u00b1\u200910.5, <jats:italic>p<\/jats:italic>\u2009=\u20090.985). Likewise, no significant differences were observed between the two groups with respect to both self- (10.9\u2009\u00b1\u20094.4 vs. 10.8\u2009\u00b1\u20094.6, <jats:italic>p<\/jats:italic>\u2009=\u20090.732) and parent-rated SDQ scores (7.2\u2009\u00b1\u20094.8 vs. 7.0\u2009\u00b1\u20094.6. <jats:italic>p<\/jats:italic>\u2009=\u20090.390). However, serum 25(OH)D (59.5\u2009\u00b1\u200932.9 vs. 46.1\u2009\u00b1\u200928.0\u00a0nmol\/L, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and mean arterial blood pressure (88.2\u2009\u00b1\u20097.4 vs. 86.5\u2009\u00b1\u20097.7\u00a0mmHg, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) were significantly higher in users than in non-users. There was a trend towards a higher rate of psychotropic drug prescription in participants taking oral contraceptive pills as compared to those not receiving hormonal contraception (17.8% vs. 14.4%, <jats:italic>p<\/jats:italic>\u2009=\u20090.052). A series of linear regression models with either KINDL-R or SDQ as dependent variable confirmed that there were no associations between components of mental well-being and contraceptive drug use, irrespective of whether self- or parent-ratings were included in these models.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>In a large, representative sample of German adolescents, exposure to exogenous contraceptive hormones was associated with higher arterial blood pressure and serum 25(OH)D concentration, whereas hormonal contraception was not linked to health-related quality of life or mental well-being.<\/jats:p>\n<\/jats:sec>","DOI":"10.1007\/s11136-020-02456-y","type":"journal-article","created":{"date-parts":[[2020,3,6]],"date-time":"2020-03-06T17:02:31Z","timestamp":1583514151000},"page":"2209-2218","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Quality of life and mental health in adolescent users of oral contraceptives. Results from the nationwide, representative German Health Interview and Examination Survey for Children and Adolescents (KiGGS)"],"prefix":"10.1007","volume":"29","author":[{"given":"Sabina Klara","family":"Lewandowski","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gunnar","family":"Duttge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Meyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,3,6]]},"reference":[{"key":"2456_CR1","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0010-7824(01)00218-9","volume":"64","author":"SA Sanders","year":"2001","unstructured":"Sanders, S. A., Graham, C. A., Bass, J. L., & Bancroft, J. (2001). 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