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The Celiac Disease Quality of Life Survey (CD-QOL) has been used in clinical research; however, its factor structure has not been confirmed and psychometric properties have not been evaluated in English-speaking adults in the U.S. Aims: (1) Confirm the factor structure of the 20-item English CD-QOL; (2) assess psychometric properties including internal consistency reliability, convergent validity, known groups validity, and incremental validity.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>453 adults with self-reported Celiac disease (<jats:italic>M<\/jats:italic><jats:sub><jats:italic>age<\/jats:italic><\/jats:sub>\u2009=\u200940.57; 88% female; 92% White) completed the CD-QOL and validated measures of generic health-related quality of life (SF-36), gluten-free diet adherence (CDAT), anxiety and depression symptoms (PROMIS), and physical symptoms (CSI) as part of the iCureCeliac<jats:sup>\u00ae<\/jats:sup> patient-powered research network.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Confirmatory factor analysis found superior fit for a bifactor structure with one general factor and four group factors. Ancillary bifactor analyses suggest the CD-QOL can be considered primarily unidimensional. Total and three subscale scores demonstrated acceptable internal consistency reliability. Convergent and known groups validity were supported. The CD-QOL demonstrated some incremental validity over the SF-36.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>The English CD-QOL can be used as a measure of disease-specific quality of life among adults with Celiac disease in the U.S. Compared to generic instruments, the CD-QOL appears to better capture specific cognitive and affective aspects of living with Celiac disease. Use of a total score is recommended. Its utility as a screening and outcome measurement tool in clinical settings should be examined.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s11136-023-03380-7","type":"journal-article","created":{"date-parts":[[2023,3,26]],"date-time":"2023-03-26T23:46:40Z","timestamp":1679874400000},"page":"2195-2208","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Psychometric validation of the celiac disease-specific quality of life survey (CD-QOL) in adults with celiac disease in the United States"],"prefix":"10.1007","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6971-3250","authenticated-orcid":false,"given":"Cara","family":"Dochat","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6489-378X","authenticated-orcid":false,"given":"Niloofar","family":"Afari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7807-5913","authenticated-orcid":false,"given":"Danielle","family":"Arigo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,3,16]]},"reference":[{"issue":"10","key":"3380_CR1","doi-asserted-by":"publisher","first-page":"1538","DOI":"10.1038\/ajg.2012.219","volume":"107","author":"A Rubio-Tapia","year":"2012","unstructured":"Rubio-Tapia, A., Ludvigsson, J. 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