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Patients with CD often experience reduced health-related quality of life that could improve with a strict adherence to a gluten-free diet (GFD).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Objectives<\/jats:title>\n                <jats:p>To obtain visual analogue scale (VAS), time trade-off (TTO) and willingness-to-pay (WTP) values amongst patients with CD.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>In 2020\u20132021, a cross-sectional online survey was conducted amongst 312 adult CD patients in Hungary. Patients completed the Gastrointestinal Symptom Rating Scale (GSRS) and evaluated their current health and three hypothetical health state vignettes defined based on dietary adherence using VAS, conventional 10-year TTO and WTP. Multivariate regressions were used to explore the effect of patients\u2019 demographic and clinical characteristics on utility and WTP values.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Mean VAS values for current health and \u2018CD with strict adherence to GFD\u2019, \u2018CD with loose adherence to GFD\u2019 and \u2018CD without GFD\u2019 hypothetical health states were 79.69\u2009\u00b1\u200918.52, 85.36\u2009\u00b1\u200916.18, 62.44\u2009\u00b1\u200919.91 and 36.69\u2009\u00b1\u200925.83, respectively. Corresponding mean TTO utilities were: 0.90\u2009\u00b1\u20090.19, 0.91\u2009\u00b1\u20090.20, 0.87\u2009\u00b1\u20090.23 and 0.76\u2009\u00b1\u20090.29. Mean annual WTP values for returning to full health were: \u20ac845\u2009\u00b1\u20091077, \u20ac648\u2009\u00b1\u20091002, \u20ac862\u2009\u00b1\u20091135 and \u20ac1251\u2009\u00b1\u20091496. Older age at diagnosis, male sex, more severe gastrointestinal symptoms (GSRS) and having comorbidities were associated with lower VAS and TTO or higher WTP values\u00a0for current own health (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>This is the first study to report TTO utilities for CD health states. Strict adherence to the GFD may result in substantial health gains in symptomatic patients. Utilities and WTP results can be used to estimate benefits of GFD in cost-utility and cost\u2013benefit analyses.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s11136-023-03418-w","type":"journal-article","created":{"date-parts":[[2023,4,17]],"date-time":"2023-04-17T07:02:52Z","timestamp":1681714972000},"page":"2503-2516","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Health utilities and willingness to pay in adult patients with coeliac disease in Hungary"],"prefix":"10.1007","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7161-6767","authenticated-orcid":false,"given":"M. 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