{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T02:52:39Z","timestamp":1790131959764,"version":"4.0.1"},"reference-count":59,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T00:00:00Z","timestamp":1771372800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T00:00:00Z","timestamp":1771372800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100018967","name":"Universitat Pompeu Fabra","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100018967","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Qual Life Res"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>There is a need for a comprehensive summary of qualitative research on the health-related quality of life (HRQoL) of people with advanced cancer requiring palliative care. We aim to systematically review qualitative studies on outcomes, needs, experiences, preferences, concerns and HRQoL of people in Europe with advanced cancer requiring palliative care over the last decade.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Protocol registered (\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/www.crd.york.ac.uk\/PROSPERO\" ext-link-type=\"uri\">www.crd.york.ac.uk\/PROSPERO<\/jats:ext-link>\n                      , CRD42024575065). The search was conducted in PubMed and Scopus, from 2013 onward. Inclusion criteria: qualitative studies addressing constructs related to the HRQoL of adults with cancer requiring palliative care in Europe. Abstracts and full texts were reviewed, data extracted, and risk of bias assessed independently by two researchers. A thematic analysis stratified by study objective was performed, grouping the emerging themes into categories (primary outcome).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 18,256 articles identified, 20 fulfilled the inclusion criteria: 10 studies with a generic objective (whole palliative process or end-of-life phase), and 10 with specific focuses. Five categories (35 themes) emerged from the studies with generic focuses: \u2018Psychological Function\u2019 (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200915), \u2018Clinical Management\u2019 (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20098), \u2018Symptoms and Physical Function\u2019 (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20096), \u2018Social Function\u2019 (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20095), and \u2018End-of-life\u2019 (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20091). Themes from the 7 studies focusing on treatment, services, and self-management also fitted into these categories, adding \u2018Spiritual Well-being\u2019.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>These findings emphasise the predominance of the psychological function domain in cancer patients requiring palliative care, including cancer-related anxiety and distress, coping mechanisms, control and decision-making, and fearing and expecting death. Additionally, clinical management unmet needs were identified in health care, information and communication, and end-of-life settings (home vs. hospital).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s11136-025-04129-0","type":"journal-article","created":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T13:54:00Z","timestamp":1771422840000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Needs and health-related quality of life domains relevant to people in Europe with advanced cancer in need of palliative care: a systematic review of qualitative research"],"prefix":"10.1007","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1690-631X","authenticated-orcid":false,"given":"Catalina","family":"Lizano-Barrantes","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9595-0970","authenticated-orcid":false,"given":"Clara","family":"Amat-Fernandez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6193-0779","authenticated-orcid":false,"given":"Olatz","family":"Garin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-7730-0658","authenticated-orcid":false,"given":"Ricardo","family":"Luer-Aguila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4982-5495","authenticated-orcid":false,"given":"Yolanda","family":"Pardo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6814-7426","authenticated-orcid":false,"given":"Leslye","family":"Rojas-Concha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6987-705X","authenticated-orcid":false,"given":"Melissa S.Y.","family":"Thong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5179-104X","authenticated-orcid":false,"given":"Giovanni","family":"Apolone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3905-1289","authenticated-orcid":false,"given":"Cinzia","family":"Brunelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0375-6204","authenticated-orcid":false,"given":"Augusto","family":"Caraceni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norbert","family":"Couespel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nanne","family":"Bos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mogens","family":"Groenvold","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stein","family":"Kaasa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2851-8605","authenticated-orcid":false,"given":"Gennaro","family":"Ciliberto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7554-449X","authenticated-orcid":false,"given":"Claudio","family":"Lombardo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo","family":"Pietrobon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4843-4663","authenticated-orcid":false,"given":"Gabriella","family":"Pravettoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-8222-0961","authenticated-orcid":false,"given":"Aude","family":"Sirven","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1259-649X","authenticated-orcid":false,"given":"Hugo","family":"Vachon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9142-1227","authenticated-orcid":false,"given":"Alexandra","family":"Gilbert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1899-5942","authenticated-orcid":false,"given":"Galina","family":"Velikova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9867-7391","authenticated-orcid":false,"given":"Montse","family":"Ferrer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"EUonQoL Working Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tudor","family":"Ciuleanu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milana","family":"Mitri\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivica","family":"Ratosa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michal","family":"Chovanec","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Vieito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e9ctor","family":"Aguilar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Ruiz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karin","family":"Ahlberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eda Tanrikulu","family":"Simsek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmut","family":"Gumus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inke","family":"van Braak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caitriona","family":"Higgins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Pinnavaia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carina","family":"Dantas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tapani","family":"Kalmi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,2,18]]},"reference":[{"issue":"3","key":"4129_CR1","doi-asserted-by":"publisher","first-page":"229","DOI":"10.3322\/caac.21834","volume":"74","author":"F Bray","year":"2024","unstructured":"Bray, F., Laversanne, M., Sung, H., Ferlay, J., Siegel, R. L., Soerjomataram, I., & Jemal, A. (2024). Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians, 74(3), 229\u2013263. https:\/\/doi.org\/10.3322\/caac.21834","journal-title":"CA: A Cancer Journal for Clinicians"},{"issue":"1","key":"4129_CR2","doi-asserted-by":"publisher","first-page":"e040808","DOI":"10.1136\/bmjopen-2020-040808","volume":"11","author":"R White","year":"2021","unstructured":"White, R., Stanley, F., Than, J., Macnair, A., Pethick, J., Fallica, G., & Maher, J. (2021). Treatable but not curable cancer in england: A retrospective cohort study using cancer registry data and linked data sets. British Medical Journal Open, 11(1), e040808. https:\/\/doi.org\/10.1136\/bmjopen-2020-040808","journal-title":"British Medical Journal Open"},{"key":"4129_CR3","unstructured":"Howlader, N., Noone, A. M., Krapcho, M., Miller, D., Brest, A., Yu, M., Ruhl, J., Tatalovich, Z., Mariotto, A., Lewis, D. R., Chen, H. S., Feuer, E. J., & Cronin, K. A. (Eds.). (1975\u20132017). SEER cancer statistics review, National Cancer Institute. Bethesda, MD. https:\/\/seer.cancer.gov\/csr\/1975_2017\/ , based on November 2019 SEER data submission, posted to the SEER web site, April 2020. (n.d.)."},{"issue":"4","key":"4129_CR4","doi-asserted-by":"publisher","first-page":"794","DOI":"10.1016\/j.jpainsymman.2019.11.009","volume":"59","author":"D Clark","year":"2020","unstructured":"Clark, D., Baur, N., Clelland, D., Garralda, E., L\u00f3pez-Fidalgo, J., Connor, S., & Centeno, C. (2020). Mapping levels of palliative care development in 198 countries: The situation in 2017. Journal of Pain and Symptom Management, 59(4), 794\u2013807e4. https:\/\/doi.org\/10.1016\/j.jpainsymman.2019.11.009","journal-title":"Journal of Pain and Symptom Management"},{"key":"4129_CR5","doi-asserted-by":"publisher","first-page":"101042","DOI":"10.1016\/j.lanepe.2024.101042","volume":"46","author":"R Hrzic","year":"2024","unstructured":"Hrzic, R., & Vogt, T. (2024). The contribution of avoidable mortality to life expectancy differences and lifespan disparities in the European union: A population-based study. The Lancet Regional Health - Europe, 46, 101042. https:\/\/doi.org\/10.1016\/j.lanepe.2024.101042","journal-title":"The Lancet Regional Health - Europe"},{"issue":"11","key":"4129_CR6","doi-asserted-by":"publisher","first-page":"1141","DOI":"10.1007\/s10654-023-01039-8","volume":"38","author":"A W\u00e9ber","year":"2023","unstructured":"W\u00e9ber, A., Laversanne, M., Nagy, P., Kenessey, I., Soerjomataram, I., & Bray, F. (2023). Gains in life expectancy from decreasing cardiovascular disease and cancer mortality \u2013 an analysis of 28 European countries 1995\u20132019. European Journal of Epidemiology, 38(11), 1141\u20131152. https:\/\/doi.org\/10.1007\/s10654-023-01039-8","journal-title":"European Journal of Epidemiology"},{"issue":"8","key":"4129_CR7","doi-asserted-by":"publisher","first-page":"1044","DOI":"10.1177\/0269216320931341","volume":"34","author":"N. Arias-Casais","year":"2020","unstructured":"Arias-Casais, N., L\u00f3pez-Fidalgo, J., Garralda, E., Pons, J. J., Rhee, J. Y., Lukas, R., & Centeno, C. (2020). Trends analysis of specialized palliative care services in 51 countries of the WHO European region in the last 14 years. Palliative Medicine, 34(8), 1044\u20131056. https:\/\/doi.org\/10.1177\/0269216320931341","journal-title":"Palliative Medicine"},{"issue":"5","key":"4129_CR8","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1007\/s11912-021-01044-8","volume":"23","author":"JM Brant","year":"2021","unstructured":"Brant, J. M., & Silbermann, M. (2021). Global perspectives on palliative care for cancer patients: Not all countries are the same. Current Oncology Reports, 23(5), 60. https:\/\/doi.org\/10.1007\/s11912-021-01044-8","journal-title":"Current Oncology Reports"},{"issue":"1","key":"4129_CR9","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1186\/s12904-018-0346-9","volume":"17","author":"T Wang","year":"2018","unstructured":"Wang, T., Molassiotis, A., Chung, B. P. M., & Tan, J. Y. (2018). Unmet care needs of advanced cancer patients and their informal caregivers: A systematic review. BMC Palliative Care, 17(1), 96. https:\/\/doi.org\/10.1186\/s12904-018-0346-9","journal-title":"BMC Palliative Care"},{"key":"4129_CR10","doi-asserted-by":"publisher","first-page":"103728","DOI":"10.1016\/j.critrevonc.2022.103728","volume":"176","author":"NH Hart","year":"2022","unstructured":"Hart, N. H., Crawford-Williams, F., Crichton, M., Yee, J., Smith, T. J., Koczwara, B., & Chan, R. J. (2022). Unmet supportive care needs of people with advanced cancer and their caregivers: A systematic scoping review. Critical Reviews in Oncology\/Hematology, 176, 103728. https:\/\/doi.org\/10.1016\/j.critrevonc.2022.103728","journal-title":"Critical Reviews in Oncology\/Hematology"},{"issue":"1","key":"4129_CR11","doi-asserted-by":"publisher","first-page":"e17450179183857","DOI":"10.2174\/0117450179183857240226094258","volume":"20","author":"M Demuro","year":"2024","unstructured":"Demuro, M., Bratzu, E., Lorrai, S., & Preti, A. (2024). Quality of life in palliative care: A systematic Meta-Review of reviews and Meta-Analyses. Clinical Practice & Epidemiology in Mental Health, 20(1), e17450179183857. https:\/\/doi.org\/10.2174\/0117450179183857240226094258","journal-title":"Clinical Practice & Epidemiology in Mental Health"},{"key":"4129_CR12","unstructured":"Public Health European Commission (2022). Europe\u2019s Beating Cancer Plan (Communication from the commission to the European Parliament and the Council) (p. 31). Brussels. Retrieved from https:\/\/health.ec.europa.eu\/system\/files\/2022-02\/eu_cancer-plan_en_0.pdf. (n.d.)."},{"key":"4129_CR13","unstructured":"EU Directorate-General for Research and Innovation (n.d.). EU Mission: Cancer. EU Mission: Cancer. Divulgation of EU missions in Horizon Europe. Retrieved from https:\/\/research-and-innovation.ec.europa.eu\/funding\/funding-opportunities\/funding-programmes-and-open-calls\/horizon-europe\/eu-missions-horizon-europe\/eu-mission-cancer_en"},{"issue":"3","key":"4129_CR14","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1016\/j.jpainsymman.2014.07.010","volume":"49","author":"SN Etkind","year":"2015","unstructured":"Etkind, S. N., Daveson, B. A., Kwok, W., Witt, J., Bausewein, C., Higginson, I. J., & Murtagh, F. E. M. (2015). Capture, Transfer, and feedback of Patient-Centered outcomes data in palliative care populations: Does it make a difference? A systematic review. Journal of Pain and Symptom Management, 49(3), 611\u2013624. https:\/\/doi.org\/10.1016\/j.jpainsymman.2014.07.010","journal-title":"Journal of Pain and Symptom Management"},{"issue":"6","key":"4129_CR15","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1200\/JCO.2015.63.0830","volume":"34","author":"E. Basch","year":"2016","unstructured":"Basch, E., Deal, A. M., Kris, M. G., Scher, H. I., Hudis, C. A., Sabbatini, P., & Schrag, D. (2016). Symptom Monitoring With Patient-Reported Outcomes During Routine Cancer Treatment: A Randomized Controlled Trial. Journal of Clinical Oncology, 34(6), 557\u2013565. https:\/\/doi.org\/10.1200\/JCO.2015.63.0830","journal-title":"Journal of Clinical Oncology"},{"issue":"19","key":"4129_CR16","doi-asserted-by":"publisher","first-page":"2336","DOI":"10.1200\/JCO.24.00542","volume":"42","author":"JJ Sanders","year":"2024","unstructured":"Sanders, J. J., Temin, S., Ghoshal, A., Alesi, E. R., Ali, Z. V., Chauhan, C., & Ferrell, B. R. (2024). Palliative care for patients with cancer: ASCO guideline update. Journal of Clinical Oncology, 42(19), 2336\u20132357. https:\/\/doi.org\/10.1200\/JCO.24.00542","journal-title":"Journal of Clinical Oncology"},{"issue":"2","key":"4129_CR17","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1093\/jamiaopen\/ooy028","volume":"1","author":"RA Bush","year":"2018","unstructured":"Bush, R. A., P\u00e9rez, A., Baum, T., Etland, C., & Connelly, C. D. (2018). A systematic review of the use of the electronic health record for patient identification, communication, and clinical support in palliative care. JAMIA Open, 1(2), 294\u2013303. https:\/\/doi.org\/10.1093\/jamiaopen\/ooy028","journal-title":"JAMIA Open"},{"issue":"1","key":"4129_CR18","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1007\/s00520-017-3895-1","volume":"26","author":"AP Kassianos","year":"2018","unstructured":"Kassianos, A. P., Ioannou, M., Koutsantoni, M., & Charalambous, H. (2018). The impact of specialized palliative care on cancer patients\u2019 health-related quality of life: A systematic review and meta-analysis. Supportive Care in Cancer, 26(1), 61\u201379. https:\/\/doi.org\/10.1007\/s00520-017-3895-1","journal-title":"Supportive Care in Cancer"},{"issue":"8","key":"4129_CR19","doi-asserted-by":"publisher","first-page":"1937","DOI":"10.1007\/s11136-018-1809-4","volume":"27","author":"J Van Roij","year":"2018","unstructured":"Van Roij, J., Fransen, H., Van De Poll-Franse, L., Zijlstra, M., & Raijmakers, N. (2018). Measuring health-related quality of life in patients with advanced cancer: A systematic review of self-administered measurement instruments. Quality of Life Research, 27(8), 1937\u20131955. https:\/\/doi.org\/10.1007\/s11136-018-1809-4","journal-title":"Quality of Life Research"},{"key":"4129_CR20","unstructured":"EUonQoL. (n.d.). EUonQoL. Retrieved November 16 (2024). from https:\/\/euonqol.eu\/"},{"key":"4129_CR21","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71","volume-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","author":"M. J. Page","year":"2021","unstructured":"Page, M. J., McKenzie, J. E., Bossuyt, P. M., Boutron, I., Hoffmann, T. C., Mulrow, C. D., & Moher, D. (2021). The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. https:\/\/doi.org\/10.1136\/bmj.n71"},{"issue":"1","key":"4129_CR22","doi-asserted-by":"publisher","first-page":"3517","DOI":"10.1186\/s12889-024-21008-4","volume":"24","author":"G Apolone","year":"2024","unstructured":"Apolone, G., Costantini, M., Caselli, L., Bos, N., Caraceni, A., Ciliberto, G., & Brunelli, C. (2024). Validation of the European oncology toolkit for the self-assessment of quality of life (EUonQoL-Kit) in cancer patients and survivors: Study protocol of a Pan European survey. Bmc Public Health, 24(1), 3517. https:\/\/doi.org\/10.1186\/s12889-024-21008-4","journal-title":"BMC Public Health"},{"issue":"6","key":"4129_CR23","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1097\/00000421-198212000-00014","volume":"5","author":"MM Oken","year":"1982","unstructured":"Oken, M. M., Creech, R. H., Tormey, D. C., Horton, J., Davis, T. E., McFadden, E. T., & Carbone, P. P. (1982). Toxicity and response criteria of the Eastern cooperative oncology group. American Journal of Clinical Oncology, 5(6), 649\u2013655.","journal-title":"American Journal of Clinical Oncology"},{"issue":"2","key":"4129_CR24","doi-asserted-by":"publisher","first-page":"100096","DOI":"10.1016\/j.esmoop.2021.100096","volume":"6","author":"A Ferrari","year":"2021","unstructured":"Ferrari, A., Stark, D., Peccatori, F. A., Fern, L., Laurence, V., Gaspar, N., & Saloustros, E. (2021). Adolescents and young adults (AYA) with cancer: A position paper from the AYA working group of the European society for medical oncology (ESMO) and the European society for paediatric oncology (SIOPE). ESMO Open, 6(2), 100096. https:\/\/doi.org\/10.1016\/j.esmoop.2021.100096","journal-title":"ESMO Open"},{"key":"4129_CR25","unstructured":"Cochrane Handbook for Systematic Reviews of Interventions (current version) | Cochrane. (n.d.). Retrieved October 2 (2025). from https:\/\/www.cochrane.org\/authors\/handbooks-and-manuals\/handbook\/current"},{"key":"4129_CR26","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-024-03884-w","volume-title":"Systematic review of the needs and health-related quality of life domains relevant to people surviving cancer in Europe","author":"C. Amat-Fernandez","year":"2025","unstructured":"Amat-Fernandez, C., Garin, O., Luer-Aguila, R., Pardo, Y., Brise\u00f1o, R., Lizano-Barrantes, C., & Ferrer, M. (2025). Systematic review of the needs and health-related quality of life domains relevant to people surviving cancer in Europe. Quality of Life Research. https:\/\/doi.org\/10.1007\/s11136-024-03884-w"},{"key":"4129_CR27","unstructured":"Questions to assist with the critical appraisal of qualitative studies (2015). Specialist unit for review evidence (SURE). Retrieved July 15, 2024, from https:\/\/www.cardiff.ac.uk\/specialist-unit-for-review-evidence\/resources\/critical-appraisal-checklists"},{"issue":"1","key":"4129_CR28","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1186\/1477-7525-10-134","volume":"10","author":"T. Bakas","year":"2012","unstructured":"Bakas, T., McLennon, S. M., Carpenter, J. S., Buelow, J. M., Otte, J. L., Hanna, K. M., & Welch, J. L. (2012). Systematic review of health-related quality of life models. Health and Quality of Life Outcomes, 10(1), 134. https:\/\/doi.org\/10.1186\/1477-7525-10-134","journal-title":"Health and Quality of Life Outcomes"},{"issue":"1","key":"4129_CR29","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1001\/jama.1995.03520250075037","volume":"273","author":"IB Wilson","year":"1995","unstructured":"Wilson, I. B., & Cleary, P. D. (1995). Linking clinical variables with Health-Related quality of life: A conceptual model of patient outcomes. Journal of the American Medical Association, 273(1), 59. https:\/\/doi.org\/10.1001\/jama.1995.03520250075037","journal-title":"Journal of the American Medical Association"},{"key":"4129_CR30","doi-asserted-by":"publisher","first-page":"102302","DOI":"10.1016\/j.ejon.2023.102302","volume":"63","author":"K Dalhammar","year":"2023","unstructured":"Dalhammar, K., Kristensson, J., Malmstr\u00f6m, M., & Rasmussen, B. H. (2023). Striving towards normality in an unpredictable situation. A qualitative interview study of how persons newly diagnosed with incurable oesophageal and gastric cancer manage everyday life. European Journal of Oncology Nursing, 63, 102302. https:\/\/doi.org\/10.1016\/j.ejon.2023.102302","journal-title":"European Journal of Oncology Nursing"},{"issue":"1","key":"4129_CR31","doi-asserted-by":"publisher","first-page":"937","DOI":"10.1186\/s12885-016-2975-9","volume":"16","author":"R Hofheinz","year":"2016","unstructured":"Hofheinz, R., Clouth, J., Borchardt-Wagner, J., Wagner, U., Weidling, E., Jen, M. H., & Br\u00fcck, P. (2016). Patient preferences for palliative treatment of locally advanced or metastatic gastric cancer and adenocarcinoma of the gastroesophageal junction: A choice-based conjoint analysis study from Germany. Bmc Cancer, 16(1), 937. https:\/\/doi.org\/10.1186\/s12885-016-2975-9","journal-title":"Bmc Cancer"},{"issue":"1","key":"4129_CR32","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1186\/s12904-019-0445-2","volume":"18","author":"L Laursen","year":"2019","unstructured":"Laursen, L., Sch\u00f8nau, M. N., Bergenholtz, H. M., Siemsen, M., Christensen, M., & Missel, M. (2019). Table in the corner: A qualitative study of life situation and perspectives of the everyday lives of oesophageal cancer patients in palliative care. BMC Palliative Care, 18(1), 60. https:\/\/doi.org\/10.1186\/s12904-019-0445-2","journal-title":"BMC Palliative Care"},{"issue":"7","key":"4129_CR33","doi-asserted-by":"publisher","first-page":"770","DOI":"10.1080\/09638288.2017.1408709","volume":"41","author":"K Loughran","year":"2019","unstructured":"Loughran, K., Rice, S., & Robinson, L. (2019). Living with incurable cancer: What are the rehabilitation needs in a palliative setting? Disability and Rehabilitation, 41(7), 770\u2013778. https:\/\/doi.org\/10.1080\/09638288.2017.1408709","journal-title":"Disability and Rehabilitation"},{"key":"4129_CR34","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/j.ejon.2018.11.008","volume":"38","author":"R Madsen","year":"2019","unstructured":"Madsen, R., Uhrenfeldt, L., & Birkelund, R. (2019). Transition experiences during courses of incurable cancer from the perspective of patients. European Journal of Oncology Nursing, 38, 13\u201320. https:\/\/doi.org\/10.1016\/j.ejon.2018.11.008","journal-title":"European Journal of Oncology Nursing"},{"issue":"1","key":"4129_CR35","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1186\/s12904-022-00984-7","volume":"21","author":"A Rodr\u00edguez-Prat","year":"2022","unstructured":"Rodr\u00edguez-Prat, A., Pergolizzi, D., Crespo, I., Balaguer, A., Porta-Sales, J., & Monforte-Royo, C. (2022). Control in patients with advanced cancer: An interpretative phenomenological study. BMC Palliat Care, 21(1), 97. https:\/\/doi.org\/10.1186\/s12904-022-00984-7","journal-title":"BMC Palliat Care"},{"issue":"1","key":"4129_CR36","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1177\/0898010115581936","volume":"34","author":"R Dobrina","year":"2016","unstructured":"Dobrina, R., Vianello, C., Tenze, M., & Palese, A. (2016). Mutual needs and wishes of cancer patients and their family caregivers during the last week of life: A descriptive phenomenological study. Journal of Holistic Nursing, 34(1), 24\u201334. https:\/\/doi.org\/10.1177\/0898010115581936","journal-title":"Journal of Holistic Nursing"},{"issue":"4","key":"4129_CR37","doi-asserted-by":"publisher","first-page":"e1194","DOI":"10.1111\/hsc.13526","volume":"30","author":"A Ivzori Erel","year":"2022","unstructured":"Ivzori Erel, A., & Cohen, M. (2022). No place like home? A qualitative study of the experience of sense of place among cancer patients near the end of life. Health and Social Care in the Community, 30(4), e1194\u2013e1201. https:\/\/doi.org\/10.1111\/hsc.13526","journal-title":"Health and Social Care in the Community"},{"issue":"1","key":"4129_CR38","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1186\/s12904-024-01489-1","volume":"23","author":"M L\u00f3pez-Salas","year":"2024","unstructured":"L\u00f3pez-Salas, M., Yanes-Rold\u00e1n, A., Fern\u00e1ndez, A., Mar\u00edn, A., Mart\u00ednez, A. I., Monroy, A., & Fern\u00e1ndez, B. (2024). End-of-life care needs in cancer patients: A qualitative study of patient and family experiences. BMC Palliative Care, 23(1), 157. https:\/\/doi.org\/10.1186\/s12904-024-01489-1","journal-title":"BMC Palliative Care"},{"issue":"5","key":"4129_CR39","doi-asserted-by":"publisher","first-page":"e0216778","DOI":"10.1371\/journal.pone.0216778","volume":"14","author":"H Stanze","year":"2019","unstructured":"Stanze, H., Schneider, N., Nauck, F., & Marx, G. (2019). I can\u2019t get it into my head that I have cancer\u2026 A qualitative interview study on needs of patients with lung cancer. PLOS ONE, 14(5), e0216778. https:\/\/doi.org\/10.1371\/journal.pone.0216778","journal-title":"PLOS ONE"},{"issue":"6","key":"4129_CR40","doi-asserted-by":"publisher","first-page":"1226","DOI":"10.1111\/hex.12417","volume":"19","author":"I Aumann","year":"2016","unstructured":"Aumann, I., Kreis, K., Damm, K., Golpon, H., Welte, T., & Schulenburg, G. V. D., J. M (2016). Treatment-related experiences and preferences of patients with lung cancer: A qualitative analysis. Health Expectations, 19(6), 1226\u20131236. https:\/\/doi.org\/10.1111\/hex.12417","journal-title":"Health Expectations"},{"issue":"9","key":"4129_CR41","doi-asserted-by":"publisher","first-page":"1168","DOI":"10.1080\/0284186X.2017.1327719","volume":"56","author":"J Bergqvist","year":"2017","unstructured":"Bergqvist, J., & Strang, P. (2017). The will to live - breast cancer patients perceptions\u2019 of palliative chemotherapy. Acta Oncologica, 56(9), 1168\u20131174. https:\/\/doi.org\/10.1080\/0284186X.2017.1327719","journal-title":"Acta Oncologica"},{"issue":"3","key":"4129_CR42","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1017\/S147895151400025X","volume":"13","author":"C H\u00e5kanson","year":"2015","unstructured":"H\u00e5kanson, C., & \u00d6hl\u00e9n, J. (2015). Meanings and experiential outcomes of bodily care in a specialist palliative context. Palliative & Supportive Care, 13(3), 625\u2013633. https:\/\/doi.org\/10.1017\/S147895151400025X","journal-title":"Palliative & Supportive Care"},{"key":"4129_CR43","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.healthplace.2018.02.003","volume":"51","author":"JL Maersk","year":"2018","unstructured":"Maersk, J. L., Cutchin, M. P., & La Cour, K. (2018). Identity and home: Understanding the experience of people with advanced cancer. Health & Place, 51, 11\u201318. https:\/\/doi.org\/10.1016\/j.healthplace.2018.02.003","journal-title":"Health & Place"},{"issue":"1","key":"4129_CR44","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1186\/s12904-022-00939-y","volume":"21","author":"TM Nys\u00e6ter","year":"2022","unstructured":"Nys\u00e6ter, T. M., Olsson, C., Sandsdalen, T., Wilde-Larsson, B., Hov, R., & Larsson, M. (2022). Preferences for home care to enable home death among adult patients with cancer in late palliative phase \u2013 a grounded theory study. BMC Palliative Care, 21(1), 49. https:\/\/doi.org\/10.1186\/s12904-022-00939-y","journal-title":"BMC Palliative Care"},{"issue":"1","key":"4129_CR45","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1080\/11038128.2016.1225815","volume":"24","author":"H Peoples","year":"2017","unstructured":"Peoples, H., Brandt, \u00c5., W\u00e6hrens, E. E., & la Cour, K. (2017). Managing occupations in everyday life for people with advanced cancer living at home. Scandinavian Journal of Occupational Therapy, 24(1), 57\u201364. https:\/\/doi.org\/10.1080\/11038128.2016.1225815","journal-title":"Scandinavian Journal of Occupational Therapy"},{"issue":"2","key":"4129_CR46","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1017\/S1478951523001335","volume":"22","author":"M S\u00f8nderup Tarp","year":"2024","unstructured":"S\u00f8nderup Tarp, M., & Rosenberg, J. (2024). The symptom burden and the assessment of palliative symptoms in patients with metastatic upper Gastrointestinal cancer: A qualitative interview study. Palliative & Supportive Care, 22(2), 367\u2013373. https:\/\/doi.org\/10.1017\/S1478951523001335","journal-title":"Palliative & Supportive Care"},{"issue":"6","key":"4129_CR47","doi-asserted-by":"publisher","first-page":"28","DOI":"10.7748\/nop.2017.e943","volume":"29","author":"M Dunham","year":"2017","unstructured":"Dunham, M., Allmark, P., & Collins, K. (2017). Older people\u2019s experiences of cancer pain: A qualitative study. Nursing Older People, 29(6), 28\u201332. https:\/\/doi.org\/10.7748\/nop.2017.e943","journal-title":"Nursing Older People"},{"key":"4129_CR48","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1016\/j.ejon.2018.01.005","volume":"33","author":"O Erol","year":"2018","unstructured":"Erol, O., Unsar, S., Yacan, L., Pelin, M., Kurt, S., & Erdogan, B. (2018). Pain experiences of patients with advanced cancer: A qualitative descriptive study. European Journal of Oncology Nursing, 33, 28\u201334. https:\/\/doi.org\/10.1016\/j.ejon.2018.01.005","journal-title":"European Journal of Oncology Nursing"},{"issue":"3","key":"4129_CR49","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1097\/NCC.0000000000000385","volume":"40","author":"G Rohde","year":"2017","unstructured":"Rohde, G., Kersten, C., Vistad, I., & Mesel, T. (2017). Spiritual Well-being in patients with metastatic colorectal cancer receiving noncurative chemotherapy: A qualitative study. Cancer Nursing, 40(3), 209\u2013216. https:\/\/doi.org\/10.1097\/NCC.0000000000000385","journal-title":"Cancer Nursing"},{"issue":"2","key":"4129_CR50","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1016\/j.jpainsymman.2016.02.012","volume":"52","author":"N McCaffrey","year":"2016","unstructured":"McCaffrey, N., Bradley, S., Ratcliffe, J., & Currow, D. C. (2016). What aspects of quality of life are important from palliative care patients\u2019 perspectives? A systematic review of qualitative research. Journal of Pain and Symptom Management, 52(2), 318\u2013328e5. https:\/\/doi.org\/10.1016\/j.jpainsymman.2016.02.012","journal-title":"Journal of Pain and Symptom Management"},{"issue":"1","key":"4129_CR51","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1001\/jamaoncol.2019.3388","volume":"6","author":"L. A. Henson","year":"2020","unstructured":"Henson, L. A., Edmonds, P., Johnston, A., Johnson, H. E., Ng Yin Ling, C., Sklavounos, A., & Gao, W. (2020). Population-Based Quality Indicators for End-of-Life Cancer Care: A Systematic Review. JAMA Oncology, 6(1), 142\u2013150. https:\/\/doi.org\/10.1001\/jamaoncol.2019.3388","journal-title":"JAMA Oncology"},{"key":"4129_CR52","doi-asserted-by":"crossref","unstructured":"Bausewein, C., Simon, S. T., Pralong, A., Radbruch, L., Nauck, F., & Voltz, R. (2015). Palliative care of adult patients with cancer. Deutsches \u00c4rzteblatt international.","DOI":"10.3238\/arztebl.2015.0863"},{"key":"4129_CR53","doi-asserted-by":"publisher","unstructured":"Kroon, L. L., van Roij, J., Korfage, I. J., Reyners, A. K. L., van den Beuken-van Everdingen, M. H. J., den Boer, M. O., \u2026 on behalf of the eQuiPe study group. (2021).Perceptions of involvement in advance care planning and emotional functioning in patients with advanced cancer. Journal of Cancer Survivorship, 15(3), 380\u2013385. https:\/\/doi.org\/10.1007\/s11764-021-01020-y","DOI":"10.1007\/s11764-021-01020-y"},{"key":"4129_CR54","doi-asserted-by":"publisher","first-page":"102354","DOI":"10.1016\/j.ejon.2023.102354","volume":"66","author":"A Kyota","year":"2023","unstructured":"Kyota, A., Kanda, K., Senuma, M., Tsukagoshi, N., Futawatari, T., & Kondo, Y. (2023). The perception of life and death in patients with end-of-life stage cancer: A systematic review of qualitative research. European Journal of Oncology Nursing, 66, 102354. https:\/\/doi.org\/10.1016\/j.ejon.2023.102354","journal-title":"European Journal of Oncology Nursing"},{"issue":"6","key":"4129_CR55","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1111\/ajco.12678","volume":"13","author":"J Nilsson","year":"2017","unstructured":"Nilsson, J., Blomberg, C., Holgersson, G., Carlsson, T., Bergqvist, M., & Bergstr\u00f6m, S. (2017). End-of-life care: Where do cancer patients want to die? A systematic review. Asia-Pacific Journal of Clinical Oncology, 13(6), 356\u2013364. https:\/\/doi.org\/10.1111\/ajco.12678","journal-title":"Asia-Pacific Journal of Clinical Oncology"},{"issue":"10","key":"4129_CR56","doi-asserted-by":"publisher","first-page":"913","DOI":"10.1177\/1049909119848148","volume":"36","author":"LT Starr","year":"2019","unstructured":"Starr, L. T., Ulrich, C. M., Corey, K. L., & Meghani, S. H. (2019). Associations among End-of-Life Discussions, Health-Care Utilization, and costs in persons with advanced cancer: A systematic review. American Journal of Hospice and Palliative Medicine, 36(10), 913\u2013926. https:\/\/doi.org\/10.1177\/1049909119848148","journal-title":"American Journal of Hospice and Palliative Medicine\u00ae"},{"key":"4129_CR57","doi-asserted-by":"publisher","unstructured":"Hoerger, M., Greer, J. A., Jackson, V. A., Park, E. R., Pirl, W. F., El-Jawahri,A., \u2026 Temel, J. S. (2018). Defining the Elements of Early Palliative Care That Are Associated With Patient-Reported Outcomes and the Delivery of End-of-Life Care. Journal of Clinical Oncology, 36(11), 1096\u20131102. https:\/\/doi.org\/10.1200\/JCO.2017.75.6676.","DOI":"10.1200\/JCO.2017.75.6676."},{"key":"4129_CR58","unstructured":"Critical Appraisal Skills Programme. (n.d.). CASP Qualitative Checklist. Retrieved July 23 (2024). from https:\/\/casp-uk.net\/checklists\/casp-qualitative-studies-checklist-fillable.pdf. (n.d.)."},{"key":"4129_CR59","unstructured":"The National Institute for Health and Care Excellence (NICE) (n.d.). Developing NICE guidelines: the manual. Retrieved from https:\/\/www.nice.org.uk\/process\/pmg20\/resources\/developing-nice-guidelines-the-manual-pdf-72286708700869"}],"updated-by":[{"DOI":"10.1007\/s11136-026-04268-y","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T00:00:00Z","timestamp":1783382400000}}],"container-title":["Quality of Life Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11136-025-04129-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11136-025-04129-0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11136-025-04129-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T07:11:40Z","timestamp":1783408300000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11136-025-04129-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,18]]},"references-count":59,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["4129"],"URL":"https:\/\/doi.org\/10.1007\/s11136-025-04129-0","relation":{},"ISSN":["0962-9343","1573-2649"],"issn-type":[{"value":"0962-9343","type":"print"},{"value":"1573-2649","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,18]]},"assertion":[{"value":"11 April 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 October 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 February 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 April 2026","order":5,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Update","order":6,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The original online version of this article was revised: Tables 1 and 2 are corrected and caption of table 3 is included.","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 July 2026","order":8,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":9,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"A Correction to this paper has been published:","order":10,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"https:\/\/doi.org\/10.1007\/s11136-026-04268-y","URL":"https:\/\/doi.org\/10.1007\/s11136-026-04268-y","order":11,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests in this study, except for author GV who declares honoraria from Pfizer, Novartis, Eisai and Lilly; Consultancy fees from AstraZeneca, Roche, Novartis, Pfizer, Seagen, Eisai and Sanofi, and an institutional grant from Pfizer.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Ethical clearance and patient consent for this research is not required, as the systematic review only uses information from previously published research.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}],"article-number":"74"}}