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Individuals with dysvascular and other chronic disease causes were excluded. Qualitative data were collected via focus groups (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200956 individuals with major extremity trauma;\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200934 clinicians) and cognitive debriefing interviews (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200941 individuals with major extremity trauma). Quantitative data were obtained through structured phone interviews with a large sample representing the target limb trauma and limb loss population (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009603). Newly developed item banks were calibrated using graded response model item response theory analysis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>LIMB-QOL includes 25 measurement scales including 10 new, targeted item banks developed with and for individuals with major limb trauma and 15 existing PRO item banks measuring salient physical, emotional, and social aspects of health-related QOL. Computer adaptive tests and short forms were programmed into the Assessment Center application programming interface and are now available through REDCap and other platforms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>LIMB-QOL provides a comprehensive and standardized system of PRO assessments for individuals with amputation or limb preservation due to sudden-onset limb injury. Research and clinical applications are discussed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s11136-026-04310-z","type":"journal-article","created":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T11:01:36Z","timestamp":1783162896000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Overview of the limb injury measurement battery for quality of life (LIMB-QOL)"],"prefix":"10.1007","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4335-4509","authenticated-orcid":false,"given":"David S.","family":"Tulsky","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2945-392X","authenticated-orcid":false,"given":"Callie E.","family":"Tyner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7349-162X","authenticated-orcid":false,"given":"Aaron J.","family":"Boulton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3234-795X","authenticated-orcid":false,"given":"Pamela A.","family":"Kisala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8199-3056","authenticated-orcid":false,"given":"Jerry","family":"Slotkin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3701-0950","authenticated-orcid":false,"given":"Christopher L.","family":"Dearth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6119-983X","authenticated-orcid":false,"given":"W. 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