{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,19]],"date-time":"2026-07-19T01:40:11Z","timestamp":1784425211877,"version":"3.55.0"},"reference-count":9,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2006,10,1]],"date-time":"2006-10-01T00:00:00Z","timestamp":1159660800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Thromb Thrombolysis"],"published-print":{"date-parts":[[2006,10]]},"DOI":"10.1007\/s11239-006-8953-3","type":"journal-article","created":{"date-parts":[[2006,9,28]],"date-time":"2006-09-28T14:27:38Z","timestamp":1159453658000},"page":"121-123","source":"Crossref","is-referenced-by-count":11,"title":["Screening for inherited thrombophilia might be warranted among Eastern Mediterranean sickle-\u00dfeta-0 thalassemia patients"],"prefix":"10.1007","volume":"22","author":[{"given":"Hussain","family":"Isma\u2019eel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. S.","family":"Arnaout","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wael","family":"Shamseddeen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Mahfouz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Zeineh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oussama","family":"Jradi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Taher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"issue":"5","key":"8953_CR1","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/j.hoc.2005.08.002","volume":"19","author":"EY Chiang","year":"2005","unstructured":"Chiang EY, Frenette PS (2005) Sickle cell vaso-occlusion. Hematol Oncol Clin North Am 19(5):771\u2013784","journal-title":"Hematol Oncol Clin North Am"},{"issue":"5","key":"8953_CR2","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1016\/j.hoc.2005.07.007","volume":"19","author":"O Castro","year":"2005","unstructured":"Castro O, Gladwin MT (2005) Pulmonary hypertension in sickle cell disease: Mechanisms, diagnosis, and management. Hematol Oncol Clin North Am 19(5):881\u2013896","journal-title":"Hematol Oncol Clin North Am"},{"key":"8953_CR3","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1182\/blood.V99.1.36","volume":"99","author":"A Eldor","year":"2002","unstructured":"Eldor A, Rachmilewitz EA (2002) The hypercoagulable state in thalassemia. Blood 99:36\u201343","journal-title":"Blood"},{"issue":"5","key":"8953_CR4","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1378\/chest.127.5.1523","volume":"127","author":"A Aessopos","year":"2005","unstructured":"Aessopos A, Farmakis D, Deftereos S, Tsironi M, Tassiopoulos S, Moyssakis I, Karagiorga M (2005) Thalassemia heart disease: A comparative evaluation of thalassemia major and thalassemia intermedia. Chest 127(5):1523\u20131530","journal-title":"Chest"},{"key":"8953_CR5","doi-asserted-by":"crossref","unstructured":"Taher A, Khalil I, Shamseddine A, El-Ahdab F, Bazarbachi A (2001) High prevalence of Factor V Leiden mutation among healthy individuals and patients with deep venous thrombosis in Lebanon: Is the Eastern Mediterranean region the area of origin of this mutation? Thromb Haemost 86(2):723\u2013724","DOI":"10.1055\/s-0037-1616118"},{"key":"8953_CR6","doi-asserted-by":"crossref","unstructured":"Tamim H, Finan RR, Almawi WY (2002) Prevalence of two thrombophilia predisposing mutations: factor V G1691A (R506Q; Leiden) and prothrombin G20210A, among healthy Lebanese. Thromb Haemost 88(4):691\u2013692.","DOI":"10.1055\/s-0037-1613280"},{"key":"8953_CR7","doi-asserted-by":"crossref","unstructured":"Isma\u2019eel H, El Accaoui R, Shamseddeen W, Taher A, Alam S, Mahfouz R, Arnaout MS (2005) Genetic thrombophilia in patients with VTE in Eastern Mediterranean located tertiary care center; Is it time to change the algorithm for thrombophilia work up decision making? J Thromb Thrombolysis (In press)","DOI":"10.1007\/s11239-006-5537-1"},{"key":"8953_CR8","doi-asserted-by":"crossref","unstructured":"Otrock ZK, Mahfouz RA, Taher AT (2005) Should we screen Eastern Mediterranean sickle beta-thalassemia patients for inherited thrombophilia? J Thromb Haemost 3(3):599\u2013600","DOI":"10.1111\/j.1538-7836.2005.01148.x"},{"key":"8953_CR9","doi-asserted-by":"crossref","unstructured":"Bauer KA (2001) The thrombophilias: Well-defined risk factors with uncertain therapeutic implications. Ann Intern Med 135:367","DOI":"10.7326\/0003-4819-135-5-200109040-00013"}],"container-title":["Journal of Thrombosis and Thrombolysis"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11239-006-8953-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11239-006-8953-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11239-006-8953-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T11:01:32Z","timestamp":1559386892000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11239-006-8953-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,10]]},"references-count":9,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2006,10]]}},"alternative-id":["8953"],"URL":"https:\/\/doi.org\/10.1007\/s11239-006-8953-3","relation":{},"ISSN":["0929-5305","1573-742X"],"issn-type":[{"value":"0929-5305","type":"print"},{"value":"1573-742X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,10]]}}}