{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T05:25:54Z","timestamp":1741325154329,"version":"3.38.0"},"reference-count":51,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82104638","82260924","82274374"],"award-info":[{"award-number":["82104638","82260924","82274374"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004761","name":"Natural Science Foundation of Hainan Province","doi-asserted-by":"publisher","award":["824MS068"],"award-info":[{"award-number":["824MS068"]}],"id":[{"id":"10.13039\/501100004761","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Thromb Thrombolysis"],"DOI":"10.1007\/s11239-025-03072-8","type":"journal-article","created":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T13:34:59Z","timestamp":1738416899000},"page":"319-330","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Shared genes and relevant potential molecular linkages between COVID-19 and chronic thromboembolic pulmonary hypertension (CTEPH)"],"prefix":"10.1007","volume":"58","author":[{"given":"Qianqian","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xia","family":"Shi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Tang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi","family":"Fu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1583-7917","authenticated-orcid":false,"given":"Xing","family":"Fu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,2,1]]},"reference":[{"key":"3072_CR1","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1038\/s41579-022-00846-2","volume":"21","author":"HE Davis","year":"2023","unstructured":"Davis HE, McCorkell L, Vogel JM, Topol EJ (2023) Long COVID: major findings, mechanisms and recommendations. Nat Rev Microbiol 21:133\u2013146. https:\/\/doi.org\/10.1038\/s41579-022-00846-2","journal-title":"Nat Rev Microbiol"},{"key":"3072_CR2","doi-asserted-by":"publisher","first-page":"1157","DOI":"10.1093\/eurheartj\/ehac031","volume":"43","author":"B Raman","year":"2022","unstructured":"Raman B, Bluemke DA, L\u00fcscher TF, Neubauer S (2022) Long COVID: post-acute sequelae of COVID-19 with a cardiovascular focus. Eur Heart J 43:1157\u20131172. https:\/\/doi.org\/10.1093\/eurheartj\/ehac031","journal-title":"Eur Heart J"},{"key":"3072_CR3","doi-asserted-by":"publisher","first-page":"993","DOI":"10.15585\/mmwr.mm6930e1","volume":"69","author":"MW Tenforde","year":"2020","unstructured":"Tenforde MW, Kim SS, Lindsell CJ et al (2020) Symptom Duration and Risk factors for delayed return to Usual Health among outpatients with COVID-19 in a Multistate Health Care Systems Network - United States, March-June 2020. MMWR Morb Mortal Wkly Rep 69:993\u2013998. https:\/\/doi.org\/10.15585\/mmwr.mm6930e1","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"3072_CR4","doi-asserted-by":"publisher","first-page":"881","DOI":"10.1016\/j.cell.2022.01.014","volume":"185","author":"Y Su","year":"2022","unstructured":"Su Y, Yuan D, Chen DG et al (2022) Multiple early factors anticipate post-acute COVID-19 sequelae. Cell 185:881\u2013895e20. https:\/\/doi.org\/10.1016\/j.cell.2022.01.014","journal-title":"Cell"},{"key":"3072_CR5","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1001\/jama.2020.12603","volume":"324","author":"A Carf\u00ec","year":"2020","unstructured":"Carf\u00ec A, Bernabei R, Landi F (2020) Persistent symptoms in patients after Acute COVID-19. JAMA 324:603\u2013605. https:\/\/doi.org\/10.1001\/jama.2020.12603","journal-title":"JAMA"},{"key":"3072_CR6","doi-asserted-by":"publisher","first-page":"108427","DOI":"10.1016\/j.clim.2020.108427","volume":"215","author":"K Yuki","year":"2020","unstructured":"Yuki K, Fujiogi M, Koutsogiannaki S (2020) COVID-19 pathophysiology: a review. Clin Immunol 215:108427. https:\/\/doi.org\/10.1016\/j.clim.2020.108427","journal-title":"Clin Immunol"},{"key":"3072_CR7","doi-asserted-by":"publisher","first-page":"n1648","DOI":"10.1136\/bmj.n1648","volume":"374","author":"H Crook","year":"2021","unstructured":"Crook H, Raza S, Nowell J et al (2021) Long covid-mechanisms, risk factors, and management. BMJ 374:n1648. https:\/\/doi.org\/10.1136\/bmj.n1648","journal-title":"BMJ"},{"key":"3072_CR8","doi-asserted-by":"publisher","first-page":"160121","DOI":"10.1183\/16000617.0121-2016","volume":"26","author":"H Gall","year":"2017","unstructured":"Gall H, Hoeper MM, Richter MJ et al (2017) An epidemiological analysis of the burden of chronic thromboembolic pulmonary hypertension in the USA, Europe and Japan. Eur Respir Rev 26:160121. https:\/\/doi.org\/10.1183\/16000617.0121-2016","journal-title":"Eur Respir Rev"},{"key":"3072_CR9","doi-asserted-by":"publisher","unstructured":"Vf T, Dm P, F X et al (2016) Monitoring for pulmonary hypertension following pulmonary embolism: the INFORM Study. Am J Med 129. https:\/\/doi.org\/10.1016\/j.amjmed.2016.03.006","DOI":"10.1016\/j.amjmed.2016.03.006"},{"key":"3072_CR10","doi-asserted-by":"publisher","first-page":"4751","DOI":"10.21037\/jtd.2018.07.106","volume":"10","author":"M Zhang","year":"2018","unstructured":"Zhang M, Wang N, Zhai Z et al (2018) Incidence and risk factors of chronic thromboembolic pulmonary hypertension after acute pulmonary embolism: a systematic review and meta-analysis of cohort studies. J Thorac Dis 10:4751\u20134763. https:\/\/doi.org\/10.21037\/jtd.2018.07.106","journal-title":"J Thorac Dis"},{"key":"3072_CR11","doi-asserted-by":"publisher","first-page":"1601792","DOI":"10.1183\/13993003.01792-2016","volume":"49","author":"YM Ende-Verhaar","year":"2017","unstructured":"Ende-Verhaar YM, Cannegieter SC, Vonk Noordegraaf A et al (2017) Incidence of chronic thromboembolic pulmonary hypertension after acute pulmonary embolism: a contemporary view of the published literature. Eur Respir J 49:1601792. https:\/\/doi.org\/10.1183\/13993003.01792-2016","journal-title":"Eur Respir J"},{"key":"3072_CR12","doi-asserted-by":"publisher","unstructured":"Fa K, Mjha K, van der Njm M et al (2020) Incidence of thrombotic complications in critically ill ICU patients with COVID-19. https:\/\/doi.org\/10.1016\/j.thromres.2020.04.013. Thrombosis research 191:","DOI":"10.1016\/j.thromres.2020.04.013"},{"key":"3072_CR13","doi-asserted-by":"publisher","first-page":"101187","DOI":"10.1016\/j.cpcardiol.2022.101187","volume":"48","author":"G Cueto-Robledo","year":"2023","unstructured":"Cueto-Robledo G, Roldan-Valadez E, Graniel-Palafox L-E et al (2023) Chronic Thromboembolic Pulmonary Hypertension (CTEPH): a review of another sequel of severe post-covid-19 pneumonia. Curr Probl Cardiol 48:101187. https:\/\/doi.org\/10.1016\/j.cpcardiol.2022.101187","journal-title":"Curr Probl Cardiol"},{"key":"3072_CR14","doi-asserted-by":"publisher","DOI":"10.1007\/s11239-024-03028-4","author":"RC Becker","year":"2024","unstructured":"Becker RC, Tantry US, Khan M, Gurbel PA (2024) The COVID-19 thrombus: distinguishing pathological, mechanistic, and phenotypic features and management. J Thromb Thrombolysis. https:\/\/doi.org\/10.1007\/s11239-024-03028-4","journal-title":"J Thromb Thrombolysis"},{"key":"3072_CR15","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1038\/s41569-021-00665-7","volume":"19","author":"DA Gorog","year":"2022","unstructured":"Gorog DA et al (2022) Current and novel biomarkers of thrombotic risk in COVID-19: a Consensus Statement from the International COVID-19 thrombosis biomarkers Colloquium. Nat Rev Cardiol 19:475\u2013495. https:\/\/doi.org\/10.1038\/s41569-021-00665-7","journal-title":"Nat Rev Cardiol"},{"key":"3072_CR16","doi-asserted-by":"publisher","first-page":"723","DOI":"10.33963\/KP.a2022.0141","volume":"80","author":"M Ciurzy\u0144ski","year":"2022","unstructured":"Ciurzy\u0144ski M, Kurzyna M, Kope\u0107 G et al (2022) An expert opinion of the Polish Cardiac Society Working Group on Pulmonary circulation on screening for chronic thromboembolic pulmonary hypertension patients after acute pulmonary embolism: update. Kardiol Pol 80:723\u2013732. https:\/\/doi.org\/10.33963\/KP.a2022.0141","journal-title":"Kardiol Pol"},{"key":"3072_CR17","doi-asserted-by":"publisher","first-page":"1395","DOI":"10.3390\/vaccines9121395","volume":"9","author":"M Wieteska-Mi\u0142ek","year":"2021","unstructured":"Wieteska-Mi\u0142ek M, Szmit S, Florczyk M et al (2021) COVID-19 vaccination in patients with pulmonary arterial hypertension and chronic Thromboembolic Pulmonary Hypertension: Safety Profile and reasons for opting against Vaccination. Vaccines (Basel) 9:1395. https:\/\/doi.org\/10.3390\/vaccines9121395","journal-title":"Vaccines (Basel)"},{"key":"3072_CR18","unstructured":"Chronic thromboembolic pulmonary hypertension: animal models - PubMed. https:\/\/pubmed.ncbi.nlm.nih.gov\/23314897\/. Accessed 18 May 2023"},{"key":"3072_CR19","doi-asserted-by":"publisher","first-page":"1990","DOI":"10.1161\/01.cir.87.6.1990","volume":"87","author":"IM Lang","year":"1993","unstructured":"Lang IM, Marsh JJ, Konopka RG et al (1993) Factors contributing to increased vascular fibrinolytic activity in mongrel dogs. Circulation 87:1990\u20132000. https:\/\/doi.org\/10.1161\/01.cir.87.6.1990","journal-title":"Circulation"},{"key":"3072_CR20","doi-asserted-by":"publisher","unstructured":"Jj M, Rg K, Im L et al (1994) Suppression of thrombolysis in a canine model of pulmonary embolism. Circulation 90. https:\/\/doi.org\/10.1161\/01.cir.90.6.3091","DOI":"10.1161\/01.cir.90.6.3091"},{"key":"3072_CR21","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1177\/2048872619840772","volume":"9","author":"J Schultz","year":"2020","unstructured":"Schultz J, Andersen A, Gade IL et al (2020) Riociguat, sildenafil and inhaled nitric oxide reduces pulmonary vascular resistance and improves right ventricular function in a porcine model of acute pulmonary embolism. Eur Heart J Acute Cardiovasc Care 9:293\u2013301. https:\/\/doi.org\/10.1177\/2048872619840772","journal-title":"Eur Heart J Acute Cardiovasc Care"},{"key":"3072_CR22","doi-asserted-by":"publisher","first-page":"1239","DOI":"10.1007\/s11239-024-03026-6","volume":"57","author":"F Galeano-Valle","year":"2024","unstructured":"Galeano-Valle F et al (2024) Comparative analysis of COVID-19-associated venous thromboembolism outcomes: evolution from 2020 to 2021\u20132022. J Thromb Thrombolysis 57:1239\u20131248. https:\/\/doi.org\/10.1007\/s11239-024-03026-6","journal-title":"J Thromb Thrombolysis"},{"key":"3072_CR23","doi-asserted-by":"publisher","first-page":"e47","DOI":"10.1093\/nar\/gkv007","volume":"43","author":"ME Ritchie","year":"2015","unstructured":"Ritchie ME, Phipson B, Wu D et al (2015) Limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic Acids Res 43:e47. https:\/\/doi.org\/10.1093\/nar\/gkv007","journal-title":"Nucleic Acids Res"},{"key":"3072_CR24","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1186\/1471-2105-9-559","volume":"9","author":"P Langfelder","year":"2008","unstructured":"Langfelder P, Horvath S (2008) WGCNA: an R package for weighted correlation network analysis. BMC Bioinformatics 9:559. https:\/\/doi.org\/10.1186\/1471-2105-9-559","journal-title":"BMC Bioinformatics"},{"key":"3072_CR25","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1186\/1471-2105-12-77","volume":"12","author":"X Robin","year":"2011","unstructured":"Robin X, Turck N, Hainard A et al (2011) pROC: an open-source package for R and S\u2009+\u2009to analyze and compare ROC curves. BMC Bioinformatics 12:77. https:\/\/doi.org\/10.1186\/1471-2105-12-77","journal-title":"BMC Bioinformatics"},{"key":"3072_CR26","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1089\/omi.2011.0118","volume":"16","author":"G Yu","year":"2012","unstructured":"Yu G, Wang L-G, Han Y, He Q-Y (2012) clusterProfiler: an R package for comparing biological themes among gene clusters. OMICS 16:284\u2013287. https:\/\/doi.org\/10.1089\/omi.2011.0118","journal-title":"OMICS"},{"key":"3072_CR27","doi-asserted-by":"publisher","first-page":"e12113","DOI":"10.1002\/pul2.12113","volume":"12","author":"PM Overton","year":"2022","unstructured":"Overton PM, Toshner M, Mulligan C et al (2022) Pulmonary thromboembolic events in COVID-19-A systematic literature review. Pulm Circ 12:e12113. https:\/\/doi.org\/10.1002\/pul2.12113","journal-title":"Pulm Circ"},{"key":"3072_CR28","doi-asserted-by":"publisher","unstructured":"Q X, S Y, M S, W L (2006) The diversity of the DnaJ\/Hsp40 family, the crucial partners for Hsp70 chaperones. Cell Mol Life Sci 63. https:\/\/doi.org\/10.1007\/s00018-006-6192-6","DOI":"10.1007\/s00018-006-6192-6"},{"key":"3072_CR29","doi-asserted-by":"publisher","unstructured":"Yc PWDB L, et al (2004) The J-protein family: modulating protein assembly, disassembly and translocation. https:\/\/doi.org\/10.1038\/sj.embor.7400172. EMBO reports 5:","DOI":"10.1038\/sj.embor.7400172"},{"key":"3072_CR30","doi-asserted-by":"publisher","first-page":"e0242960","DOI":"10.1371\/journal.pone.0242960","volume":"15","author":"W Salibe-Filho","year":"2020","unstructured":"Salibe-Filho W, Araujo TLS, Melo G E, et al (2020) Shear stress-exposed pulmonary artery endothelial cells fail to upregulate HSP70 in chronic thromboembolic pulmonary hypertension. PLoS ONE 15:e0242960. https:\/\/doi.org\/10.1371\/journal.pone.0242960","journal-title":"PLoS ONE"},{"key":"3072_CR31","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1186\/1475-2859-8-9","volume":"8","author":"O Kolaj","year":"2009","unstructured":"Kolaj O, Spada S, Robin S, Wall JG (2009) Use of folding modulators to improve heterologous protein production in Escherichia coli. Microb Cell Fact 8:9. https:\/\/doi.org\/10.1186\/1475-2859-8-9","journal-title":"Microb Cell Fact"},{"key":"3072_CR32","unstructured":"Human heat shock protein 70 enhances tumor antigen presentation through complex formation and intracellular antigen delivery without innate immune signaling - PubMed. https:\/\/pubmed.ncbi.nlm.nih.gov\/17684010\/. Accessed 18 May 2023"},{"key":"3072_CR33","unstructured":"Partial complex I deficiency due to the CNS conditional ablation of Ndufa5 results in a mild chronic encephalopathy but no increase in oxidative damage - PubMed. https:\/\/pubmed.ncbi.nlm.nih.gov\/24154540\/. Accessed 18 May 2023"},{"key":"3072_CR34","doi-asserted-by":"publisher","first-page":"923502","DOI":"10.3389\/fmed.2022.923502","volume":"9","author":"S Hirschberger","year":"2022","unstructured":"Hirschberger S, Gellert L, Effinger D et al (2022) Ketone bodies improve human CD8\u2009+\u2009cytotoxic T-Cell Immune Response during COVID-19 infection. Front Med (Lausanne) 9:923502. https:\/\/doi.org\/10.3389\/fmed.2022.923502","journal-title":"Front Med (Lausanne)"},{"key":"3072_CR35","doi-asserted-by":"publisher","unstructured":"Dc L-A, Ph W, Wj K, S G (2015) Interactions between mitochondrial reactive oxygen species and cellular glucose metabolism. Arch Toxicol 89. https:\/\/doi.org\/10.1007\/s00204-015-1520-y","DOI":"10.1007\/s00204-015-1520-y"},{"key":"3072_CR36","doi-asserted-by":"publisher","first-page":"1192","DOI":"10.1158\/1078-0432.CCR-21-3114","volume":"28","author":"PL Triozzi","year":"2022","unstructured":"Triozzi PL, Stirling ER, Song Q et al (2022) Circulating Immune Bioenergetic, metabolic, and genetic signatures predict Melanoma patients\u2019 response to Anti-PD-1 Immune Checkpoint Blockade. Clin Cancer Res 28:1192\u20131202. https:\/\/doi.org\/10.1158\/1078-0432.CCR-21-3114","journal-title":"Clin Cancer Res"},{"key":"3072_CR37","doi-asserted-by":"publisher","first-page":"1628","DOI":"10.1161\/ATVBAHA.117.309184","volume":"37","author":"TP Fidler","year":"2017","unstructured":"Fidler TP, Middleton EA, Rowley JW et al (2017) Glucose transporter 3 potentiates degranulation and is required for platelet activation. Arterioscler Thromb Vasc Biol 37:1628\u20131639. https:\/\/doi.org\/10.1161\/ATVBAHA.117.309184","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"3072_CR38","doi-asserted-by":"publisher","unstructured":"Fernandez-Fernandez B, D\u2019Marco L, G\u00f3rriz JL et al (2020) Exploring Sodium glucose co-transporter-2 (SGLT2) inhibitors for Organ Protection in COVID-19. J Clin Med 9(2030). https:\/\/doi.org\/10.3390\/jcm9072030","DOI":"10.3390\/jcm9072030"},{"key":"3072_CR39","doi-asserted-by":"publisher","first-page":"4095","DOI":"10.3390\/ijms23084095","volume":"23","author":"M Tolomeo","year":"2022","unstructured":"Tolomeo M, Cavalli A, Cascio A (2022) STAT1 and its crucial role in the control of viral infections. Int J Mol Sci 23:4095. https:\/\/doi.org\/10.3390\/ijms23084095","journal-title":"Int J Mol Sci"},{"key":"3072_CR40","doi-asserted-by":"publisher","first-page":"106886","DOI":"10.1016\/j.vph.2021.106886","volume":"139","author":"Y Liu","year":"2021","unstructured":"Liu Y, Hu R, Zhu J et al (2021) The lncRNA PAHRF functions as a competing endogenous RNA to regulate MST1 expression by sponging miR-23a-3p in pulmonary arterial hypertension. Vascul Pharmacol 139:106886. https:\/\/doi.org\/10.1016\/j.vph.2021.106886","journal-title":"Vascul Pharmacol"},{"key":"3072_CR41","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s11523-018-0587-9","volume":"14","author":"S Sammons","year":"2019","unstructured":"Sammons S, Kornblum NS, Blackwell KL (2019) Fulvestrant-based combination therapy for second-line treatment of hormone receptor-positive advanced breast Cancer. Target Oncol 14:1\u201312. https:\/\/doi.org\/10.1007\/s11523-018-0587-9","journal-title":"Target Oncol"},{"key":"3072_CR42","doi-asserted-by":"publisher","first-page":"e151347","DOI":"10.1172\/JCI151347","volume":"131","author":"B Chakraborty","year":"2021","unstructured":"Chakraborty B, Byemerwa J, Shepherd J et al (2021) Inhibition of estrogen signaling in myeloid cells increases tumor immunity in melanoma. J Clin Invest 131:e151347. https:\/\/doi.org\/10.1172\/JCI151347","journal-title":"J Clin Invest"},{"key":"3072_CR43","doi-asserted-by":"publisher","unstructured":"Bravaccini S, Nicolini F, Balzi W et al (2021) Tamoxifen protects breast cancer patients from COVID-19: first evidence from real world data. https:\/\/doi.org\/10.21203\/rs.3.rs-598923\/v1","DOI":"10.21203\/rs.3.rs-598923\/v1"},{"key":"3072_CR44","doi-asserted-by":"publisher","first-page":"897","DOI":"10.1007\/s11239-021-02413-7","volume":"51","author":"D Giannis","year":"2021","unstructured":"Giannis D et al (2021) Incidence of venous thromboembolism and mortality in patients with initial presentation of COVID-19. J Thromb Thrombolysis 51:897\u2013901. https:\/\/doi.org\/10.1007\/s11239-021-02413-7","journal-title":"J Thromb Thrombolysis"},{"key":"3072_CR45","doi-asserted-by":"publisher","first-page":"106564","DOI":"10.1016\/j.envint.2021.106564","volume":"154","author":"B Bowe","year":"2021","unstructured":"Bowe B, Xie Y, Gibson AK et al (2021) Ambient fine particulate matter air pollution and the risk of hospitalization among COVID-19 positive individuals: Cohort study. Environ Int 154:106564. https:\/\/doi.org\/10.1016\/j.envint.2021.106564","journal-title":"Environ Int"},{"key":"3072_CR46","doi-asserted-by":"publisher","first-page":"109650","DOI":"10.1016\/j.envres.2020.109650","volume":"187","author":"JL Domingo","year":"2020","unstructured":"Domingo JL, Rovira J (2020) Effects of air pollutants on the transmission and severity of respiratory viral infections. Environ Res 187:109650. https:\/\/doi.org\/10.1016\/j.envres.2020.109650","journal-title":"Environ Res"},{"key":"3072_CR47","doi-asserted-by":"publisher","first-page":"E69","DOI":"10.3978\/j.issn.2072-1439.2016.01.19","volume":"8","author":"Y-F Xing","year":"2016","unstructured":"Xing Y-F, Xu Y-H, Shi M-H, Lian Y-X (2016) The impact of PM2.5 on the human respiratory system. J Thorac Dis 8:E69\u201374. https:\/\/doi.org\/10.3978\/j.issn.2072-1439.2016.01.19","journal-title":"J Thorac Dis"},{"key":"3072_CR48","doi-asserted-by":"publisher","unstructured":"Ms D, Td K (2022) Innate immunity: the first line of defense against SARS-CoV-2. https:\/\/doi.org\/10.1038\/s41590-021-01091-0. Nature immunology 23:","DOI":"10.1038\/s41590-021-01091-0"},{"key":"3072_CR49","doi-asserted-by":"publisher","first-page":"1256","DOI":"10.1007\/s11239-024-03021-x","volume":"57","author":"D Wu","year":"2024","unstructured":"Wu D et al (2024) The use of non-vitamin K antagonist oral anticoagulants in chronic thromboembolic pulmonary hypertension: an updated meta-analysis. J Thromb Thrombolysis 57:1256\u20131267. https:\/\/doi.org\/10.1007\/s11239-024-03021-x","journal-title":"J Thromb Thrombolysis"},{"key":"3072_CR50","doi-asserted-by":"publisher","unstructured":"L C, S I, L T, et al (2017) Particulate matter exposure is associated with inflammatory gene methylation in obese subjects. Environ Res 152:. https:\/\/doi.org\/10.1016\/j.envres.2016.11.002","DOI":"10.1016\/j.envres.2016.11.002"},{"key":"3072_CR51","doi-asserted-by":"publisher","first-page":"3296","DOI":"10.3390\/jcm9103296","volume":"9","author":"A Zahra","year":"2020","unstructured":"Zahra A, Sisu C, Silva E et al (2020) Is there a link between Bisphenol A (BPA), a key endocrine disruptor, and the risk for SARS-CoV-2 infection and severe COVID-19? J Clin Med 9:3296. https:\/\/doi.org\/10.3390\/jcm9103296","journal-title":"J Clin Med"}],"container-title":["Journal of Thrombosis and Thrombolysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11239-025-03072-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11239-025-03072-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11239-025-03072-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T00:25:59Z","timestamp":1741307159000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11239-025-03072-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,1]]},"references-count":51,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2025,2]]}},"alternative-id":["3072"],"URL":"https:\/\/doi.org\/10.1007\/s11239-025-03072-8","relation":{},"ISSN":["1573-742X"],"issn-type":[{"type":"electronic","value":"1573-742X"}],"subject":[],"published":{"date-parts":[[2025,2,1]]},"assertion":[{"value":"9 December 2024","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 February 2025","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors report there are no competing interests to declare.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}