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The ethics committee: the Animal Ethics Committee of Nanchang University. The number or ID of the ethics approval: NCULAE-202209280017.Considering the availability of ducks and the advantages of DHBV, we chose ducks as the experimental material. We cumulative used 60 male ducks to study the HGD system and its application. According to the \u201claboratory animal-Requirements of environment and housing facilities\u201d (GB 14925-2010, Standardization Administration of the People\u2019s Republic of China), all ducks were under the conditions of room temperature (24\u2009\u00b1\u20090.5\u00a0\u00b0C), humidity (50\u2009\u00b1\u200910%), light (12\u00a0h light\/dark cycle) and were free access to diet. According to the \u201cTechnical specifications on euthanasia of laboratory animals\u201d (RB\/T 061-2021, Certification and Accreditation Administration of the People\u2019s Republic of China), the ducks were euthanized with excessive isoflurane at the end of study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}