{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T12:51:10Z","timestamp":1768740670955,"version":"3.49.0"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2016,6,17]],"date-time":"2016-06-17T00:00:00Z","timestamp":1466121600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2016,6,17]],"date-time":"2016-06-17T00:00:00Z","timestamp":1466121600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"name":"72nd Birthday Anniversary of His Majesty the King\u2019s Scholarship","award":["GCUCE12-1"],"award-info":[{"award-number":["GCUCE12-1"]}]},{"DOI":"10.13039\/501100004396","name":"Thailand Research Fund","doi-asserted-by":"publisher","award":["RTA5700085"],"award-info":[{"award-number":["RTA5700085"]}],"id":[{"id":"10.13039\/501100004396","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012895","name":"Zoetis","doi-asserted-by":"crossref","award":["B826R-TH-13-249"],"award-info":[{"award-number":["B826R-TH-13-249"]}],"id":[{"id":"10.13039\/100012895","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Trop Anim Health Prod"],"published-print":{"date-parts":[[2016,10]]},"DOI":"10.1007\/s11250-016-1099-1","type":"journal-article","created":{"date-parts":[[2016,6,17]],"date-time":"2016-06-17T10:17:30Z","timestamp":1466158650000},"page":"1351-1359","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Efficacy of Fostera\u00ae PRRS modified live virus (MLV) vaccination strategy against a Thai highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) infection"],"prefix":"10.1007","volume":"48","author":[{"given":"Ponlakrit","family":"Charoenchanikran","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roongtham","family":"Kedkovid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chaitawat","family":"Sirisereewan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yonlayong","family":"Woonwong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jirapat","family":"Arunorat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Panchan","family":"Sitthichareonchai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natthawan","family":"Sopipan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suphattra","family":"Jittimanee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sawang","family":"Kesdangsakonwut","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roongroje","family":"Thanawongnuwech","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,6,17]]},"reference":[{"key":"1099_CR1","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1006\/viro.1993.1129","volume":"193","author":"K-K Conzelmann","year":"1993","unstructured":"Conzelmann, K.-K., Visser, N., Van Woensel, P., and Thiel, H.-J., 1993. Molecular characterization of porcine reproductive and respiratory syndrome virus, a member of the arterivirus group, Virology, 193, 329\u2013339.","journal-title":"Virology"},{"key":"1099_CR2","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1016\/j.virusres.2010.07.017","volume":"154","author":"L Darwich","year":"2010","unstructured":"Darwich, L., D\u00edaz, I., and Mateu, E., 2010. Certainties, doubts and hypotheses in porcine reproductive and respiratory syndrome virus immunobiology, Virus Research, 154, 123\u2013132.","journal-title":"Virus Research"},{"key":"1099_CR3","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1016\/j.vetmic.2015.06.013","volume":"179","author":"DT Do","year":"2015","unstructured":"Do, D.T., Park, C., Choi, K., Jeong, J., Nguyen, T.T., Nguyen, K.D., and Chae, C., 2015. Comparison of two genetically distant type 2 porcine reproductive and respiratory syndrome virus (PRRSV) modified live vaccines against Vietnamese highly pathogenic PRRSV, Veterinary Microbiology, 179, 233\u2013241.","journal-title":"Veterinary Microbiology"},{"key":"1099_CR4","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/S0166-0934(01)00358-5","volume":"98","author":"C Egli","year":"2001","unstructured":"Egli, C., Th\u00fcr, B., Liu, L., and Hofmann, M.A., 2001. Quantitative TaqMan\u00ae RT-PCR for the detection and differentiation of European and North American strains of porcine reproductive and respiratory syndrome virus, Journal of Virological Methods, 98, 63\u201375.","journal-title":"Journal of Virological Methods"},{"key":"1099_CR5","doi-asserted-by":"publisher","first-page":"648","DOI":"10.1177\/030098589503200606","volume":"32","author":"P Halbur","year":"1995","unstructured":"Halbur, P., Paul, P., Frey, M., Landgraf, J., Eernisse, K., Meng, X.-J., Lum, M., Andrews, J., and Rathje, J., 1995. Comparison of the pathogenicity of two US porcine reproductive and respiratory syndrome virus isolates with that of the Lelystad virus, Veterinary Pathology, 32, 648\u2013660.","journal-title":"Veterinary Pathology"},{"key":"1099_CR6","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1016\/j.tvjl.2012.06.035","volume":"195","author":"K Han","year":"2013","unstructured":"Han, K., Seo, H., Oh, Y., Kang, I., Park, C., and Chae, C., 2013. Comparison of the virulence of European and North American genotypes of porcine reproductive and respiratory syndrome virus in experimentally infected pigs, The Veterinary Journal, 195, 313\u2013318.","journal-title":"The Veterinary Journal"},{"key":"1099_CR7","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1016\/j.vetmic.2015.01.017","volume":"176","author":"T Jantafong","year":"2015","unstructured":"Jantafong, T., Sangtong, P., Saenglub, W., Mungkundar, C., Romlamduan, N., Lekchareonsuk, C., and Lekcharoensuk, P., 2015. Genetic diversity of porcine reproductive and respiratory syndrome virus in Thailand and Southeast Asia from 2008 to 2013, Veterinary Microbiology, 176, 229\u2013238.","journal-title":"Veterinary Microbiology"},{"key":"1099_CR8","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1016\/j.vetimm.2004.09.010","volume":"102","author":"W Johnson","year":"2004","unstructured":"Johnson, W., Roof, M., Vaughn, E., Christopher-Hennings, J., Johnson, C.R., and Murtaugh, M.P., 2004. Pathogenic and humoral immune responses to porcine reproductive and respiratory syndrome virus (PRRSV) are related to viral load in acute infection, Veterinary Immunology and Immunopathology, 102, 233\u2013247.","journal-title":"Veterinary Immunology and Immunopathology"},{"key":"1099_CR9","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1743-422X-6-177","volume":"6","author":"KL Klinge","year":"2009","unstructured":"Klinge, K.L., Vaughn, E.M., Roof, M.B., Bautista, E.M., and Murtaugh, M.P., 2009. Age-dependent resistance to Porcine reproductive and respiratory syndrome virus replication in swine, Virology Journal, 6, 1.","journal-title":"Virology Journal"},{"key":"1099_CR10","doi-asserted-by":"crossref","first-page":"39","DOI":"10.56808\/2985-1130.1957","volume":"34","author":"P Laohasittikul","year":"2004","unstructured":"Laohasittikul, P., Boonarpha, N., Pongprapachuen, Y., Kesdangsakonwut, S., Wangnaitham, S., and Thanawongnuwech, R., 2004. Antigen distribution of porcine reproductive and respiratory syndrome virus (PRRSV) in Thai crossbred pigs using immunohistochemistry, Thai Journal of Veterinary Medicine. 34, 39\u201348.","journal-title":"Thai Journal of Veterinary Medicine."},{"key":"1099_CR11","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/416727","author":"X Li","year":"2014","unstructured":"Li, X., Galliher-Beckley, A., Pappan, L., Trible, B., Kerrigan, M., Beck, A., Hesse, R., Blecha, F., Nietfeld, J.C., and Rowland, R., 2014. Comparison of host immune responses to homologous and heterologous type II porcine reproductive and respiratory syndrome virus (PRRSV) challenge in vaccinated and unvaccinated pigs, BioMed Research International, doi: 10.1155\/2014\/416727.","journal-title":"BioMed Research International"},{"key":"1099_CR12","doi-asserted-by":"publisher","first-page":"594","DOI":"10.1089\/vim.2004.17.594","volume":"17","author":"L Lohse","year":"2004","unstructured":"Lohse, L., Nielsen, J., and Eriksen, L., 2004. Temporary CD8+ T-cell depletion in pigs does not exacerbate infection with porcine reproductive and respiratory syndrome virus (PRRSV), Viral Immunology, 17, 594\u2013603.","journal-title":"Viral Immunology"},{"key":"1099_CR13","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/S0042-6822(03)00009-6","volume":"309","author":"WA Meier","year":"2003","unstructured":"Meier, W.A., Galeota, J., Osorio, F.A., Husmann, R.J., Schnitzlein, W.M., and Zuckermann, F.A., 2003. Gradual development of the interferon-\u03b3 response of swine to porcine reproductive and respiratory syndrome virus infection or vaccination, Virology, 309, 18\u201331.","journal-title":"Virology"},{"key":"1099_CR14","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/S0378-1135(00)00196-6","volume":"74","author":"X Meng","year":"2000","unstructured":"Meng, X., 2000. Heterogeneity of porcine reproductive and respiratory syndrome virus: implications for current vaccine efficacy and future vaccine development, Veterinary Microbiology, 74, 309\u2013329.","journal-title":"Veterinary Microbiology"},{"key":"1099_CR15","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/S0378-1135(02)00427-3","volume":"93","author":"WL Mengeling","year":"2003","unstructured":"Mengeling, W.L., Lager, K.M., Vorwald, A.C., and Koehler, K.J., 2003. Strain specificity of the immune response of pigs following vaccination with various strains of porcine reproductive and respiratory syndrome virus, Veterinary Microbiology, 93, 13\u201324.","journal-title":"Veterinary Microbiology"},{"key":"1099_CR16","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1006\/viro.1993.1008","volume":"192","author":"JJ Meulenberg","year":"1993","unstructured":"Meulenberg, J.J., Hulst, M.M., de Meijer, E.J., Moonen, P.L., den Besten, A., de Kluyver, E.P., Wensvoort, G., and Moormann, R.J., 1993. Lelystad virus, the causative agent of porcine epidemic abortion and respiratory syndrome (PEARS), is related to LDV and EAV, Virology, 192, 62\u201372.","journal-title":"Virology"},{"key":"1099_CR17","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1111\/j.1865-1682.2011.01309.x","volume":"59","author":"SN Na Ayudhya","year":"2012","unstructured":"Na Ayudhya, S.N., Assavacheep, P., and Thanawongnuwech, R., 2012. One World\u2013One Health: the threat of emerging swine diseases. an Asian perspective, Transboundary and Emerging Diseases, 59, 9\u201317.","journal-title":"Transboundary and Emerging Diseases"},{"key":"1099_CR18","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1016\/S0378-1135(96)01334-X","volume":"55","author":"J Nielsen","year":"1997","unstructured":"Nielsen, J., and B\u00f8tner, A., 1997. Hematological and immunological parameters of 412-month old pigs infected with PRRS virus, Veterinary Microbiology, 55, 289\u2013294.","journal-title":"Veterinary Microbiology"},{"key":"1099_CR19","doi-asserted-by":"publisher","first-page":"2039","DOI":"10.3201\/eid1812.111105","volume":"18","author":"D Nilubol","year":"2012","unstructured":"Nilubol, D., Tripipat, T., Hoonsuwan, T., and Kortheerakul, K., 2012. Porcine reproductive and respiratory syndrome virus, Thailand, 2010\u20132011, Emerging Infectious Diseases, 18, 2039\u20132043.","journal-title":"Emerging Infectious Diseases"},{"key":"1099_CR20","doi-asserted-by":"publisher","first-page":"432","DOI":"10.1016\/j.vetmic.2014.05.030","volume":"172","author":"C Park","year":"2014","unstructured":"Park, C., Seo, H.W., Han, K., Kang, I., and Chae, C., 2014. Evaluation of the efficacy of a new modified live porcine reproductive and respiratory syndrome virus (PRRSV) vaccine (Fostera PRRS) against heterologous PRRSV challenge, Veterinary Microbiology, 172, 432\u2013442.","journal-title":"Veterinary Microbiology"},{"key":"1099_CR21","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1177\/104063879400600102","volume":"6","author":"KD Rossow","year":"1994","unstructured":"Rossow, K.D., Bautista, E.M., Goyal, S.M., Molitor, T.W., Murtaugh, M.P., Morrison, R.B., Benfield, D.A., and Collins, J.E., 1994. Experimental porcine reproductive and respiratory syndrome virus infection in one-, four-, and 10-week-old pigs, Journal of Veterinary Diagnostic Investigation, 6, 3\u201312.","journal-title":"Journal of Veterinary Diagnostic Investigation"},{"key":"1099_CR22","doi-asserted-by":"publisher","first-page":"8700","DOI":"10.1128\/JVI.02551-09","volume":"84","author":"M Shi","year":"2010","unstructured":"Shi, M., Lam, T.T.-Y., Hon, C.-C., Murtaugh, M.P., Davies, P.R., Hui, R.K.-H., Li, J., Wong, L.T.-W., Yip, C.-W., and Jiang, J.-W., 2010. Phylogeny-based evolutionary, demographical, and geographical dissection of North American type 2 porcine reproductive and respiratory syndrome viruses, Journal of Virology, 84, 8700\u20138711.","journal-title":"Journal of Virology"},{"key":"1099_CR23","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/S0378-1135(98)00245-4","volume":"63","author":"R Thanawongnuwech","year":"1998","unstructured":"Thanawongnuwech, R., Thacker, E.L., and Halbur, P.G., 1998. Influence of pig age on virus titer and bactericidal activity of porcine reproductive and respiratory syndrome virus (PRRSV)-infected pulmonary intravascular macrophages (PIMs), Veterinary Microbiology, 63, 177\u2013187.","journal-title":"Veterinary Microbiology"},{"key":"1099_CR24","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0000526","volume":"2","author":"K Tian","year":"2007","unstructured":"Tian, K., Yu, X., Zhao, T., Feng, Y., Cao, Z., Wang, C., Hu, Y., Chen, X., Hu, D., and Tian, X., 2007. Emergence of fatal PRRSV variants: unparalleled outbreaks of atypical PRRS in China and molecular dissection of the unique hallmark, PLoS One, 2, e526.","journal-title":"PLoS One"},{"key":"1099_CR25","doi-asserted-by":"publisher","first-page":"1952","DOI":"10.1016\/S0264-410X(02)00822-8","volume":"21","author":"I Van der Linden","year":"2003","unstructured":"Van der Linden, I., Voermans, J., Van der Linde-Bril, E., Bianchi, A., and Steverink, P., 2003. Virological kinetics and immunological responses to a porcine reproductive and respiratory syndrome virus infection of pigs at different ages, Vaccine, 21, 1952\u20131957.","journal-title":"Vaccine"},{"key":"1099_CR26","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1006\/viro.2001.1034","volume":"287","author":"W-H Wu","year":"2001","unstructured":"Wu, W.-H., Fang, Y., Farwell, R., Steffen-Bien, M., Rowland, R.R., Christopher-Hennings, J., and Nelson, E.A., 2001. A 10-kDa structural protein of porcine reproductive and respiratory syndrome virus encoded by ORF2b, Virology, 287, 183\u2013191.","journal-title":"Virology"},{"key":"1099_CR27","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1046\/j.1365-2567.1996.494570.x","volume":"87","author":"F Zuckermann","year":"1996","unstructured":"Zuckermann, F., and Husmann, R., 1996. Functional and phenotypic analysis of porcine peripheral blood CD4\/CD8 double-positive T cells, Immunology, 87, 500.","journal-title":"Immunology"}],"container-title":["Tropical Animal Health and Production"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11250-016-1099-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11250-016-1099-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11250-016-1099-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,17]],"date-time":"2024-06-17T18:19:03Z","timestamp":1718648343000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11250-016-1099-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6,17]]},"references-count":27,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2016,10]]}},"alternative-id":["1099"],"URL":"https:\/\/doi.org\/10.1007\/s11250-016-1099-1","relation":{},"ISSN":["0049-4747","1573-7438"],"issn-type":[{"value":"0049-4747","type":"print"},{"value":"1573-7438","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,6,17]]},"assertion":[{"value":"23 February 2016","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 June 2016","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 June 2016","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}