{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T10:05:20Z","timestamp":1791281120989,"version":"4.1.0"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Trop Anim Health Prod"],"published-print":{"date-parts":[[2017,2]]},"DOI":"10.1007\/s11250-016-1201-8","type":"journal-article","created":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T14:12:19Z","timestamp":1480601539000},"page":"231-238","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":67,"title":["A systematic review of leptospirosis on dogs, pigs, and horses in Latin America"],"prefix":"10.1007","volume":"49","author":[{"given":"Priscila S.","family":"Pinto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo","family":"Libonati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2434-8728","authenticated-orcid":false,"given":"Walter","family":"Lilenbaum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,12,1]]},"reference":[{"key":"1201_CR1","first-page":"251","volume":"387","author":"B Adler","year":"2015","unstructured":"Adler, B., 2015. Vaccines against leptospirosis. Current Topics in Microbiology and Immunology, 387, 251-272.","journal-title":"Current Topics in Microbiology and Immunology"},{"issue":"3-4","key":"1201_CR2","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.vetmic.2009.03.012","volume":"140","author":"B Adler","year":"2010","unstructured":"Adler, B. and De La Pe\u00f1a Moctezuma, A, 2010. Leptospira and leptospirosis. Veterinary Microbiology, 140(3-4), 287-296.","journal-title":"Veterinary Microbiology"},{"issue":"3","key":"1201_CR3","first-page":"195","volume":"51","author":"SN Ahmad","year":"2005","unstructured":"Ahmad, S.N., Shah, S. and Ahmad, F.M.H., 2005. Laboratory Diagnosis of leptospirosis. Journal of Postgraduate Medicine, 51(3), 195-200.","journal-title":"Journal of Postgraduate Medicine"},{"issue":"2","key":"1201_CR4","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.actatropica.2007.10.012","volume":"105","author":"DA Athanazio","year":"2008","unstructured":"Athanazio, D.A., Silva, E.F., Santos, C.S., Rocha, G.M., Vannier-Santos, M.A., McBride, A.J.A., Ko, A.I. and Reis, M.G., 2008. Rattus norvegicus as a model for persistent renal colonization by pathogenic Leptospira interrogans. Acta Tropica, 105(2), 176\u2013180.","journal-title":"Acta Tropica"},{"issue":"6","key":"1201_CR5","doi-asserted-by":"crossref","first-page":"1952","DOI":"10.1590\/S0102-311X2005000600046","volume":"21","author":"RD Blazius","year":"2005","unstructured":"Blazius, R.D., Rom\u00e3o, P.R.T., Blazius, E.M.C.G. and da Silva, O.S., 2005. Ocorr\u00eancia de c\u00e3es errantes soropositivos para Leptospira spp. na cidade de Itapema, Santa Catarina, Brasil. Cadernos de Sa\u00fade P\u00fablica, 21(6), 1952-1956.","journal-title":"Cadernos de Sa\u00fade P\u00fablica"},{"issue":"2","key":"1201_CR6","first-page":"174","volume":"33","author":"ACB Delbem","year":"2002","unstructured":"Delbem, A.C.B., Freitas J.C., Bracarense A.P.F.R.L., Muller E.E. and Oliveira R.C., 2002. Leptospirosis in slaughtered sows: serological and histopathological investigation. Brazilian Journal of Microbiology, 33(2), 174\u2013177.","journal-title":"Brazilian Journal of Microbiology"},{"issue":"3","key":"1201_CR7","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1590\/S0103-84782004000300029","volume":"34","author":"ACB Delbem","year":"2004","unstructured":"Delbem, A.C.B., Freire L.R., Silva C.A., Muller E.E., Dias R.A., Neto J.S.F. and Freitas J.C., 2004. Fatores de risco associados \u00e0 soropositividade para leptospirose em matrizes su\u0131\u00ednas. Ci\u00eancia Rural, 34(3), 847\u2013852.","journal-title":"Ci\u00eancia Rural"},{"key":"1201_CR8","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1017\/S0950268810002074","volume":"139","author":"A Desvars","year":"2011","unstructured":"Desvars, A., Cardinale, E. and Michault, A., 2011. Animal leptospirosis in small tropical areas. Epidemiology Infection, 139, 167\u2013188.","journal-title":"Epidemiology Infection"},{"key":"1201_CR9","first-page":"99","volume":"387","author":"WA Ellis","year":"2015","unstructured":"Ellis, W.A., 2015. Animal leptospirosis. Current Topics in Microbiology and Immunology, 387, 99\u2013137.","journal-title":"Current Topics in Microbiology and Immunology"},{"key":"1201_CR10","volume-title":"Leptospira and Leptospirosis","author":"S Faine","year":"1999","unstructured":"Faine, S., Adler, B., Bolin, C. and Perolat, P., 1999. Leptospira and Leptospirosis, (MediSci, Melborne)."},{"issue":"4","key":"1201_CR11","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1590\/S0103-84782002000400011","volume":"32","author":"ACM Favero","year":"2002","unstructured":"Favero, A.C.M., Pinheiro S.R., Vasconcellos S.A., Morais Z.M., Ferreira F. and Ferreira Neto J.S., 2002. Most frequent serovars of leptospires in serological tests of buffaloes, sheep, goats, horses, swine and dogs from several Brazilian states. Ci\u00eancia Rural, 32(4), 613\u2013619.","journal-title":"Ci\u00eancia Rural"},{"issue":"4","key":"1201_CR12","first-page":"344","volume":"37","author":"\u00cdL Figueiredo","year":"2013","unstructured":"Figueiredo, \u00cd.L., Alves, C.J., Silva, L.C.A., Oliveira, R.M. and Azevedo, S.S., 2013. Leptospirose su\u00edna: uma importante causa de falhas e perdas reprodutivas. Revista Brasileira de Reprodu\u00e7\u00e3o Animal, 37(4), 344-353.","journal-title":"Revista Brasileira de Reprodu\u00e7\u00e3o Animal"},{"issue":"3","key":"1201_CR13","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.mimet.2012.06.005","volume":"90","author":"F Fornazari","year":"2012","unstructured":"Fornazari, F., Da Silva, R.C., Richini-Pereira, V.B., Beserra, H.E., Luvizotto, M.C. and Langoni, H., 2012. Comparison of conventional PCR, quantitative PCR, bacteriological culture and the Warthin Starry technique to detect Leptospira spp. in kidney and liver samples from naturally infected sheep from Brazil. Journal of Microbiological Methods, 90(3), 321-326.","journal-title":"Journal of Microbiological Methods"},{"issue":"5","key":"1201_CR14","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.biologicals.2013.06.010","volume":"41","author":"MA Guerra","year":"2013","unstructured":"Guerra, M.A., 2013. Leptospirosis: public health perspectives. Biologicals, 41(5), 295-297.","journal-title":"Biologicals"},{"issue":"1","key":"1201_CR15","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/s11259-013-9582-x","volume":"38","author":"C Hamond","year":"2014","unstructured":"Hamond, C., Martins, G., Loureiro, A.P., Pestana, C., Lawson-Ferreira, R., Medeiros, M.A. and Lilenbaum, W., 2014. Urinary PCR as an increasingly useful tool for an accurate diagnosis of leptospirosis in livestock. Veterinary Research Communications, 38(1), 81\u201385.","journal-title":"Veterinary Research Communications"},{"issue":"2-4","key":"1201_CR16","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/j.vetmic.2010.08.020","volume":"148","author":"DJ Houwers","year":"2011","unstructured":"Houwers, D.J., Goris, M.G., Abdoel, T., Kas, J.A., Knobbe, S.S., van Dongen, A.M., Westerduin, F.E., Klein, W.R. and Hartskeerl, R.A., 2011. Agglutinating antibodies against pathogenic Leptospira in healthy dogs and horses indicate common exposure and regular occurrence of subclinical infections. Veterinary Microbiology, 148(2-4), 449\u2013451.","journal-title":"Veterinary Microbiology"},{"issue":"4","key":"1201_CR17","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1590\/S0074-02762011000400009","volume":"106","author":"RSP Jorge","year":"2011","unstructured":"Jorge, R.S.P., Ferreira, F., Neto, J.S.F., Vasconcellos, S.A., Lima, E.S., de Morais, Z.M. and de Souza, G.O., 2011. Exposure of free-ranging wild carnivores, horses and domestic dogs to Leptospira spp. in the northern Pantanal, Brazil. Mem\u00f3rias do Instituto Oswaldo Cruz, 106(4), 441-444.","journal-title":"Mem\u00f3rias do Instituto Oswaldo Cruz"},{"issue":"11","key":"1201_CR18","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.2460\/javma.231.11.1709","volume":"231","author":"R Kasimanickam","year":"2007","unstructured":"Kasimanickam, R., Whittier, W.D., Collins, J.C., Currin, J.F., Inman, B., Hall, J.B. and Pelzer, K.D., 2007. A field study of the effects of a monovalent Leptospira borgpetersenii serovar Hardjo strain Hardjobovis vaccine administered with oxytetracycline on reproductive performance in beef cattle. Journal of the American Veterinary Medical Association, 231(11), 1709-1714.","journal-title":"Journal of the American Veterinary Medical Association"},{"issue":"1","key":"1201_CR19","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1590\/S1678-91992012000100016","volume":"18","author":"M Kikuti","year":"2012","unstructured":"Kikuti, M., Langoni, H., Nobrega, D.N., Corr\u00eaa, A.P.F.L. and Ullmann, L.S., 2012. Occurrence and risk factors associated with canine leptospirosis. Journal of Venomous Animals and Toxins Including Tropical Diseases, 18(1), 124-127.","journal-title":"Journal of Venomous Animals and Toxins Including Tropical Diseases"},{"issue":"10","key":"1201_CR20","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/j.trstmh.2010.07.002","volume":"104","author":"CL Lau","year":"2010","unstructured":"Lau, C.L., Smythe, L.D., Craig, S.B. and Weinstein, P., 2010. Climate change, flooding, urbanization and leptospirosis: fuelling the fire? Transactions of the Royal Society of Tropical Medicine and Hygiene, 104(10), 631-8.","journal-title":"Transactions of the Royal Society of Tropical Medicine and Hygiene"},{"issue":"1","key":"1201_CR21","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1186\/s12917-015-0341-9","volume":"11","author":"M Lelu","year":"2015","unstructured":"Lelu, M., Munoz-Zanzi, C., Higgins, B. and Galloway, R., 2015. Seroepidemiology of leptospirosis in dogs from rural and slum communities of Los Rios Region, Chile. BMC Veterinary Research, 11(1), 31.","journal-title":"BMC Veterinary Research"},{"issue":"6","key":"1201_CR22","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.cair.2004.08.001","volume":"4","author":"PN Levett","year":"2004","unstructured":"Levett, P. N., 2004. Leptospirosis: A forgotten zoonosis? Clinical and Applied Immunology Reviews, 4(6), 435-448.","journal-title":"Clinical and Applied Immunology Reviews"},{"key":"1201_CR23","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1186\/1746-6148-9-237","volume":"9","author":"G Martins","year":"2013","unstructured":"Martins, G. and Lilenbaum, W., 2013. The panorama of animal leptospirosis in Rio de Janeiro, Brazil, regarding the seroepidemiology of the infection in tropical regions. BMC Veterinary Research, 9, 237.","journal-title":"BMC Veterinary Research"},{"issue":"3","key":"1201_CR24","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1111\/j.1939-1676.2011.0704.x","volume":"25","author":"MD Miller","year":"2011","unstructured":"Miller, M.D., Annis, K.M., Lappin, M.R. and Lunn, K.F., 2011. Variability in results of the microscopic agglutination test in dogs with clinical leptospirosis and dogs vaccinated against leptospirosis. Journal of Veterinary Internal Medicine, 25(3), 426-432.","journal-title":"Journal of Veterinary Internal Medicine"},{"issue":"5","key":"1201_CR25","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1354\/vp.08-VP-0265-N-REV","volume":"46","author":"AM Monahan","year":"2009","unstructured":"Monahan, A.M., Callanan, J.J. and Nally, J.E., 2009. Review paper: Host-pathogen interactions in the kidney during chronic leptospirosis. Veterinary Pathology, 46(5), 792-799.","journal-title":"Veterinary Pathology"},{"issue":"6","key":"1201_CR26","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1017\/S0950268813001817","volume":"142","author":"L Mughini-Gras","year":"2014","unstructured":"Mughini-Gras, L., Bonfanti, L., Natale, A., Comin, A., Ferronato, A., La Greca, E., Patregnani, T., Lucchese, L. and Marangon, S., 2014. Application of an integrated outbreak management plan for the control of leptospirosis in dairy cattle herds. Epidemiology and Infection, 142(6), 1172-1181.","journal-title":"Epidemiology and Infection"},{"issue":"3","key":"1201_CR27","doi-asserted-by":"crossref","first-page":"497","DOI":"10.4269\/ajtmh.13-0334","volume":"90","author":"C Munoz-Zanzi","year":"2014","unstructured":"Munoz-Zanzi, C., Mason, M., Encina, C., Gonzalez, M. and Berg, S., 2014. Household characteristics associated with rodent presence and Leptospira infection in rural and urban communities from southern Chile. The American Journal of Tropical Medicine and Hygiene, 90(3), 497\u2013506.","journal-title":"The American Journal of Tropical Medicine and Hygiene"},{"key":"1201_CR28","unstructured":"OIE (2014) Leptospirosis, In: Manual of diagnostic tests and vaccines for terrestrial animals. World Organization for Animal Health, Paris."},{"issue":"13","key":"1201_CR29","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1136\/vr.100490","volume":"170","author":"DY Otaka","year":"2012","unstructured":"Otaka, D.Y., Martins, G., Hamond, C., Penna, B., Medeiros, M.A. and Lilenbaum, W., 2012. Serology and PCR for bovine leptospirosis: herd and individual approaches. Veterinary Record, 170(13), 338\u2013339.","journal-title":"Veterinary Record"},{"issue":"1","key":"1201_CR30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.medmal.2012.11.005","volume":"43","author":"M Picardeau","year":"2013","unstructured":"Picardeau, M., 2013. Diagnosis and epidemiology of leptospirosis. M\u00e9dicine et Maladies Infectieuses, 43(1), 1\u20139.","journal-title":"M\u00e9dicine et Maladies Infectieuses"},{"issue":"2","key":"1201_CR31","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1136\/vr.e296","volume":"170","author":"AE Pinna","year":"2012","unstructured":"Pinna, A.E., Martins, G. and Lilenbaum, W., 2012. Leptospirosis and embryo recovery rate in mares. Veterinary Record, 170(2), 60.","journal-title":"Veterinary Record"},{"key":"1201_CR32","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.actatropica.2015.05.008","volume":"149","author":"PS Pinto","year":"2015","unstructured":"Pinto, P.S., Loureiro, A.P., Penna, B. and Lilenbaum, W., 2015. Usage of Leptospira spp. local strains as antigens increases the sensitivity of the serodiagnosis of bovine leptospirosis. Acta Tropica, 149, 163-167.","journal-title":"Acta Tropica"},{"issue":"6","key":"1201_CR33","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1177\/1040638714553293","volume":"26","author":"DR Rissi","year":"2014","unstructured":"Rissi, D.R. and Brown, C.A., 2014. Diagnostic features in 10 naturally occurring cases of acute fatal canine leptospirosis. Journal of Veterinary Diagnostic Investigation, 26(6), 799-804.","journal-title":"Journal of Veterinary Diagnostic Investigation"},{"issue":"3","key":"1201_CR34","doi-asserted-by":"crossref","first-page":"156","DOI":"10.4102\/jsava.v81i3.139","volume":"81","author":"JM Roach","year":"2010","unstructured":"Roach, J.M., van Vuuren, M. and Picard, J.A., 2010. A serological survey of antibodies to Leptospira species in dogs in South Africa. Journal of the South African Veterinary Association, 81(3), 156\u2013159.","journal-title":"Journal of the South African Veterinary Association"},{"issue":"2","key":"1201_CR35","first-page":"189","volume":"81","author":"C Roqueplo","year":"2013","unstructured":"Roqueplo, C., Cabre, O., Davoust, B. and Kodjo, A., 2013. Epidemiological study of animal Leptospirosis in New Caledonia. Veterinary Medicine International, 81(2), 189-197.","journal-title":"Veterinary Medicine International"},{"issue":"7","key":"1201_CR36","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1590\/S0100-736X2012000700003","volume":"32","author":"AMC Sarmento","year":"2012","unstructured":"Sarmento, A.M.C., Azevedo, S.S., Morais, Z.M., Souza, G.O., Oliveira, F.C.S., Gon\u00e7ales, A.P., Miraglia, F. and Vasconcellos, S.A., 2012. Use of Leptospira spp. strains isolated in Brazil in the microscopic agglutination test applied to diagnosis of leptospirosis in cattle herds in eight Brazilian states. Pesquisa Veterin\u00e1ria Brasileira, 32(7), 601-606.","journal-title":"Pesquisa Veterin\u00e1ria Brasileira"},{"issue":"4","key":"1201_CR37","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1080\/00480169.2011.579554","volume":"59","author":"S Subharat","year":"2011","unstructured":"Subharat, S., Wilson, P.R., Heuer, C. and Collins-Emerson, J.M., 2011. Vaccination for leptospirosis improved the weaning percentage of 2-year-old farmed red deer hinds in New Zealand. New Zealand Veterinary Journal, 59(4), 191-196.","journal-title":"New Zealand Veterinary Journal"},{"issue":"7","key":"1201_CR38","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1017\/S0950268809990902","volume":"138","author":"SM Suepaul","year":"2010","unstructured":"Suepaul, S.M., Carrington, C.V., Campbell, M., Borde, G. and Adesiyun, A.A., 2010. Serovars of Leptospira isolated from dogs and rodents. Epidemiology & Infection, 138(7), 1059-1070.","journal-title":"Epidemiology & Infection"},{"issue":"2","key":"1201_CR39","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1007\/s11250-010-9698-8","volume":"43","author":"SM Suepaul","year":"2011","unstructured":"Suepaul, S.M., Carrington, C.V., Campbell, M., Borde, G. and Adesiyun A.A., 2011. Seroepidemiology of leptospirosis in livestock in Trinidad. Tropical Animal Health and Production, 43(2), 367\u2013375.","journal-title":"Tropical Animal Health and Production"},{"issue":"1","key":"1201_CR40","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1939-1676.2010.0654.x","volume":"25","author":"JE Sykes","year":"2011","unstructured":"Sykes, J.E., Hartmann, K., Lunn, K.F., Moore, G.E., Stoddard, R.A. and Goldstein, R.E., 2011. Small animal consensus statement on leptospirosis: diagnosis, epidemiology, treatment, and prevention. Journal of Veterinary Internal Medicine, 25(1), 1-13.","journal-title":"Journal of Veterinary Internal Medicine"},{"key":"1201_CR41","doi-asserted-by":"crossref","first-page":"954","DOI":"10.3923\/pjbs.2012.742.747","volume":"15","author":"AK Verma","year":"2012","unstructured":"Verma, A.K., Kumar, A., Dhama, K., Deb, R., Rahal, A., Mahima and Chakraborty, S., 2012. Leptospirosis - persistence of a dilemma: an overview with particular emphasis on trends and recent advances in vaccines and vaccination strategies. Pakistan Journal of Biological Sciences, 15, 954-963.","journal-title":"Pakistan Journal of Biological Sciences"},{"key":"1201_CR42","unstructured":"WHO, 2010. Human leptospirosis: guidance for diagnosis, surveillance and control. World Health Organization."}],"container-title":["Tropical Animal Health and Production"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11250-016-1201-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11250-016-1201-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11250-016-1201-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,25]],"date-time":"2017-06-25T01:03:20Z","timestamp":1498352600000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11250-016-1201-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12,1]]},"references-count":42,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,2]]}},"alternative-id":["1201"],"URL":"https:\/\/doi.org\/10.1007\/s11250-016-1201-8","relation":{},"ISSN":["0049-4747","1573-7438"],"issn-type":[{"value":"0049-4747","type":"print"},{"value":"1573-7438","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,12,1]]}}}