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Seventy-two Californian does of 5\u00a0months age and average body weight of 3250\u2009\u00b1\u200978.2\u00a0g were randomly allotted into six groups, each of 12 does. All does orally receive 3\u00a0ml distilled water for 10\u00a0days before mating and 28\u00a0days during pregnancy. Treatments were repeated for four consecutive parities. The first group served as control (C) given distilled water only, however the second, third, fourth and fifth groups were supplemented with 3\u00a0ml distilled water containing 0.2\u00a0ml SY, 200\u00a0mg DPP, 200\u00a0mg BP, 0.2\u00a0ml HB\/doe per day, respectively. While, the sixth group does were given all previous ingredients (MIX). Sexual receptivity rate, fertility rate, kindling rate, and newborn traits were recorded. Also, maternal feed intake, feed conversion ratio, and digestibility coefficients of nutrients were recorded. Does in all groups were artificially inseminated with 0.5\u00a0ml of fresh heterospermic semen of 15 fertile bucks extended in Tris at 806\u20131006 sperm\/ml. Treatment increased maternal body weight and daily gain with highest values (\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u20090.05) in BP, SY, and MIX does. All treatments enhanced feed intake and feed conversion ratio (FCR) compared with control. Number services per conception decreased (\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u20090.01), while litter size and weight and survival at birth and weaning increased (\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u20090.01) in treated than control does. Treated does produced more milk than control. Digestibility coefficients of all nutrients were improved (\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u20090.01) in treated does. In conclusion, supporting rabbit does pre- and during pregnancy with diets supplemented with a mixture of honey bee, date palm pollen, bee pollen, and synbiotic improves the productive and reproductive performances of rabbit does and their offspring.\n                  <\/jats:p>","DOI":"10.1007\/s11250-024-04166-w","type":"journal-article","created":{"date-parts":[[2024,10,11]],"date-time":"2024-10-11T20:01:50Z","timestamp":1728676910000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Bioactive compounds enrichment in rabbit doe\u2019s diet pre-and during pregnancy improves productive and reproductive performance and cost-effectiveness under hot climates"],"prefix":"10.1007","volume":"56","author":[{"given":"Mohamed E.","family":"El-Speiy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8743-5397","authenticated-orcid":false,"given":"Moustafa M.","family":"Zeitoun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed A.","family":"El-Sawy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tarek A.","family":"Sadaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bahaa M.","family":"Abou-Shehema","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed M.","family":"Abdella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hossam A.","family":"Shahba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmoud R.","family":"Habib","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,10,12]]},"reference":[{"key":"4166_CR1","doi-asserted-by":"publisher","first-page":"46","DOI":"10.9790\/3008-10314651","volume":"10","author":"MH Abd El-Azim","year":"2015","unstructured":"Abd El-Azim MH, Yassin FA, Khalil SA, El-Mesalamy AM (2015) Hydrocarbons, fatty acids and biological activity of date palm pollen (Phoenix dactylifera L.) growing in Egypt. 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