{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T20:03:23Z","timestamp":1785528203296,"version":"3.56.0"},"reference-count":64,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T00:00:00Z","timestamp":1782086400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T00:00:00Z","timestamp":1782086400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Trop Anim Health Prod"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1007\/s11250-026-05120-8","type":"journal-article","created":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T11:42:17Z","timestamp":1782128537000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Relative abundance of genes regulating proliferation and apoptosis of corpus luteum during cold and hot seasons in Egyptian buffaloes"],"prefix":"10.1007","volume":"58","author":[{"given":"Samaa M.","family":"Galal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sally","family":"Ibrahim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karima","family":"Mahmoud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ola","family":"Adel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aya A.","family":"Shokry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. S.","family":"El-Belely","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. T.","family":"Ismail","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,6,22]]},"reference":[{"key":"5120_CR1","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1016\/j.bbagen.2005.06.018","volume":"10","author":"KH Al-Gubory","year":"2005","unstructured":"Al-Gubory KH, Ceballos-Picot I, Nicole A (2005) Changes in activities of superoxide dismutase, nitric oxide synthase, glutathione-dependent enzymes and the incidence of apoptosis in sheep corpus luteum during the estrous cycle. Biochim Biophys Acta 10:348\u2013357","journal-title":"Biochim Biophys Acta"},{"key":"5120_CR2","doi-asserted-by":"publisher","first-page":"5245","DOI":"10.1158\/0008-5472.CAN-04-0496","volume":"64","author":"CL Andersen","year":"2004","unstructured":"Andersen CL, Jensen JL, \u00d8rntoft TF (2004) Normalization of real-time quantitative reverse transcription-PCR data: a model based variance estimation approach to identify genes suited for normalization, applied to bladder and colon cancer data sets. Cancer Res 64:5245\u20135250","journal-title":"Cancer Res"},{"key":"5120_CR3","doi-asserted-by":"publisher","first-page":"00127","DOI":"10.15406\/jdvar.2017.05.00127","volume":"5","author":"PR Archana","year":"2017","unstructured":"Archana PR, Aleena J, Pragana P, Vidya MK, AbdulNiyas PA, Bagath M, Krishnan G, Manimaran A, Beena V, Kurien EK, Sejian V, Bahtta R (2017) Role of heat shock proteins in livestock adaptation to heat stress. J Dairy Vet Anim Res 5:00127. https:\/\/doi.org\/10.15406\/jdvar.2017.05.00127","journal-title":"J Dairy Vet Anim Res"},{"key":"5120_CR4","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1016\/j.anireprosci.2013.06.008","volume":"140","author":"RK Baithalua","year":"2013","unstructured":"Baithalua RK, Singha SK, Guptaa C, Rajaa AK, Saxenaa A, Kumar Y, Singhb R, Agarwal SK (2013) Cellular and functional characterization of buffalo (Bubalusbubalis) corpus luteum during the estrous cycle and pregnancy. Anim Reprod Sci 140:138\u2013146","journal-title":"Anim Reprod Sci"},{"key":"5120_CR5","unstructured":"Bancroft JD, Gamble M (2008) Theory and practice of histological techniques. Elsevier Health Sciences 2008"},{"key":"5120_CR6","first-page":"305","volume":"19","author":"B Berisha","year":"2002","unstructured":"Berisha B, Schams D, Miyamoto A (2002) The expression of angiotensin and endothelin system members in bovine corpus luteum during estrous cycle and pregnancy. Endocrinol 19:305\u2013312","journal-title":"Endocrinol"},{"key":"5120_CR7","doi-asserted-by":"publisher","first-page":"17760","DOI":"10.1074\/jbc.M117.794743","volume":"292","author":"GTK Boopathy","year":"2017","unstructured":"Boopathy GTK, Kulkarni M, Ho SY, Boey A, Chua EWM, Barathi VA, Carney TJ, Wang X, Hong W (2017) Cavin-2 regulates the activity and stability of endothelial nitric-oxide synthase (eNOS) in angiogenesis. J Biol Chem 292:17760\u201317776","journal-title":"J Biol Chem"},{"key":"5120_CR8","first-page":"167","volume":"40","author":"E Capper","year":"2001","unstructured":"Capper E, Marshall LA (2001) Mammalian phospholipases A(2).mediators of inflammation, proliferation and apoptosis. Europe PMC 40:167\u2013197","journal-title":"Europe PMC"},{"key":"5120_CR9","doi-asserted-by":"publisher","first-page":"137","DOI":"10.17221\/1742-CJAS","volume":"54","author":"EM Chmelikova","year":"2009","unstructured":"Chmelikova EM, Sedm\u00edkov\u00e1 J, Petr T, Kott V, L\u00e1nsk\u00e1 L, T\u00f9mov\u00e1 H, Tichovsk\u00e1 MJ (2009) Expression and localization of nitric oxide synthase isoforms during porcine oocyte growth and acquisition of meiotic competence. Czech J Anim Sci 54:137\u2013149","journal-title":"Czech J Anim Sci"},{"key":"5120_CR10","doi-asserted-by":"publisher","first-page":"1949","DOI":"10.2741\/davis1","volume":"7","author":"JS Davis","year":"2002","unstructured":"Davis JS, Rueda BR (2002) The corpus luteum: an ovarian structure with maternal instincts and suicidal tendencies. Front Biosci 7:1949\u20131978","journal-title":"Front Biosci"},{"key":"5120_CR11","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1016\/j.tem.2005.07.009","volume":"16","author":"F Deshayes","year":"2005","unstructured":"Deshayes F, Nahmias C (2005) Angiotensin receptors: a new role in cancer? Trends Endocrinol Metab 16:293\u2013299","journal-title":"Trends Endocrinol Metab"},{"key":"5120_CR12","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1530\/JOE-12-0252","volume":"215","author":"FX Donadeu","year":"2012","unstructured":"Donadeu FX, Schauer SN, Sontakke SD (2012) Involvement of miRNAs in ovarian follicular andluteal development. J Endocrinol 215:323\u2013333","journal-title":"J Endocrinol"},{"key":"5120_CR13","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1016\/j.theriogenology.2011.08.002","volume":"77","author":"PK Dubey","year":"2012","unstructured":"Dubey PK, Tripathi V, Singh RP, Saikumar G, Nath A, Pratheesh MD, Gade N, Sharma GT (2012) Expression of nitric oxide synthase isoforms in different stages of buffalo (Bubalusbubalis) ovarian follicles: effect of nitric oxide on in vitro development of preantral follicle. Therio 77:280\u2013291","journal-title":"Therio"},{"key":"5120_CR14","doi-asserted-by":"crossref","unstructured":"Dulin NO, Alexander LD, Harwalkar S, Falck JR, Douglas JG (1998) Phospholipase A2-mediated activation of mitogen-activated protein kinase by angiotensin II.ProcNatlAcadSci USA. 95:8098\u20138102","DOI":"10.1073\/pnas.95.14.8098"},{"key":"5120_CR15","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1017\/S0967199418000072","volume":"26","author":"A El-Sayed","year":"2018","unstructured":"El-Sayed A, Nagy R, El-Asheeri AK, Eid LN (2018) Developmental and molecular responses of buffalo (Bubalusbubalis) cumulus\u2013oocyte complex matured in vitro under heat shock conditions. Zygote 26:177\u2013192","journal-title":"Zygote"},{"key":"5120_CR16","doi-asserted-by":"publisher","first-page":"93","DOI":"10.21608\/ejap.2019.92864","volume":"56","author":"MS Faheem","year":"2019","unstructured":"Faheem MS, Dessouki SHM (2019) Expression of selected candidate genes during different stages of corpus luteum development in cyclic Egyptian buffaloes. Egypt j Anim Prod 56:93\u201399","journal-title":"Egypt j Anim Prod"},{"key":"5120_CR17","unstructured":"FAO (2020) http:\/\/www.faostatfao.org"},{"key":"5120_CR18","doi-asserted-by":"publisher","first-page":"829","DOI":"10.1093\/eurheartj\/ehr304","volume":"33","author":"U F\u00f6rstermann","year":"2012","unstructured":"F\u00f6rstermann U, Sessa WC (2012) Nitric Oxide Synthases: Regulation and Function. Eur Heart J 33:829\u2013837","journal-title":"Eur Heart J"},{"key":"5120_CR19","doi-asserted-by":"publisher","first-page":"2431","DOI":"10.17582\/journal.aavs\/2022\/10.11.2431.2437","volume":"10","author":"S Galal","year":"2022","unstructured":"Galal S, Ibrahim S, Mahmoud K, Adel O, Shokry AA, El-Belely MS, Ismail ST (2022) Expression pattern of apoptotic genes during different Stages of corpus luteum development in egyptian buffaloes. Adv Anim Veterinary Sci 10:2431\u20132437","journal-title":"Adv Anim Veterinary Sci"},{"key":"5120_CR20","doi-asserted-by":"publisher","first-page":"1188","DOI":"10.17582\/journal.aavs\/2020\/8.11.1188.1193","volume":"8","author":"M Hamouda","year":"2020","unstructured":"Hamouda M, Saber A, Al-Shabebi A (2020) Incidence of infertility in female buffaloes due to some reproductive disorders. Adv Anim Veterinary Sci 8:1188\u20131193","journal-title":"Adv Anim Veterinary Sci"},{"key":"5120_CR21","doi-asserted-by":"publisher","first-page":"38211","DOI":"10.1038\/srep38211","volume":"6","author":"T Hojo","year":"2016","unstructured":"Hojo T, Siemieniuch MJ, Lukasik K, Piotrowska-Tomala KK, Jonczyk AW, Okuda K, Skarzynski DJ (2016) Programmed necrosis - a new mechanism of steroidogenic luteal cell death and elimination during luteolysis in cows. Sci Rep 6:38211","journal-title":"Sci Rep"},{"key":"5120_CR22","first-page":"1280","volume":"29","author":"K Horihata","year":"2016","unstructured":"Horihata K, Yoshioka S, Sano M, Yamamoto Y, Kimura K, Skarzynski DJ, Okuda K (2016) Expressions of lipoprotein receptors and cholesterol efflux regulatory proteins during luteolysis in bovine corpus luteum. Reproduction, Fertility and Development. CSIRO Publishing 29:1280\u20131286","journal-title":"CSIRO Publishing"},{"key":"5120_CR23","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1186\/s43141-022-00320-9","volume":"20","author":"S Ibrahim","year":"2022","unstructured":"Ibrahim S, Taqi MO, Sosa ASA, ElNaby AHH, Mahmoud KGM, Darwish HRH, Abd El Hameed AR, Nawito MF (2022) Spatiotemporal expression pattern of miR-205, miR-26a-5p, miR17-5p, let-7b-5p and their target genes during different stages of corpus luteum in Egyptian buffaloes. J Genetic Eng Biotechnol 20:37\u201347","journal-title":"J Genetic Eng Biotechnol"},{"key":"5120_CR24","doi-asserted-by":"publisher","unstructured":"Jianfang W, Raza SHA, Pant SD, Juan Z, Prakash A, Abdelnour SA, Aloufi BH, Mahasneh ZMH, Amin AA, Shokrollahi B, Zan L (2025) Exploring epigenetic and genetic modulation in animal responses to thermal stress. Mol Biotechnol https:\/\/doi.org\/10.1007\/s12033-024-01126-5","DOI":"10.1007\/s12033-024-01126-5"},{"key":"5120_CR25","doi-asserted-by":"publisher","first-page":"1021","DOI":"10.1161\/01.HYP.0000016179.52601.B4","volume":"39","author":"XQ Jin","year":"2002","unstructured":"Jin XQ, Fukuda N, Su JZ, Lai YM, Suzuki R, Tahira Y (2002) AT2 receptor gene transfer downregulates AT1a receptor in vascular smooth muscle cells. Hypertension 39:1021\u20131027","journal-title":"Hypertension"},{"key":"5120_CR26","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1016\/j.anireprosci.2008.08.001","volume":"113","author":"UR Jyotsna","year":"2009","unstructured":"Jyotsna UR, Medhamurthy R (2009) Standardization and validation of an induced ovulation model system in buffalo cows: Characterization of gene expression changes in the periovulatory follicle. Anim Reprod Sci 113:71\u201381","journal-title":"Anim Reprod Sci"},{"key":"5120_CR27","doi-asserted-by":"publisher","first-page":"1393","DOI":"10.1111\/rda.13787","volume":"55","author":"K Kapoor","year":"2020","unstructured":"Kapoor K, Singh O, Pathak D (2020) Immunoexpression of cytokine tumor necrosis factor-\u03b1 suggesting its role in formation and regression of corpus luteum in Indian buffalo. Reprod Dom Anim 55:1393\u20131403","journal-title":"Reprod Dom Anim"},{"key":"5120_CR28","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1262\/jrd.2012-186","volume":"59","author":"S Kawaguchi","year":"2013","unstructured":"Kawaguchi S, Sakumoto R, Okuda K (2013) Induction of the expressions of antioxidant enzymes by luteinizing hormone in the bovine corpus luteum. J Reprod Dev 59:219\u2013224","journal-title":"J Reprod Dev"},{"key":"5120_CR30","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1677\/joe.0.1700369","volume":"170","author":"S Kobayashi","year":"2001","unstructured":"Kobayashi S, Berisha B, Amselgruber WM, Schams D, Miyamoto A (2001) Production and localization of angiotensin II in the bovine early corpus luteum: possible interaction with luteal angiogenic factors and prostaglandin F2. J Endocrinol 170:369\u2013380","journal-title":"J Endocrinol"},{"key":"5120_CR29","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1262\/jrd.48.583","volume":"48","author":"S Kobayashi","year":"2002","unstructured":"Kobayashi S, Acosta TJ, Hayashi K (2002) Intraluteal release of prostaglandin F2alpha and E2 during corpora lutea development in the cow. J Reprod Dev 48:583\u2013590","journal-title":"J Reprod Dev"},{"key":"5120_CR32","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1262\/jrd.50.411","volume":"50","author":"A Korzekwa","year":"2004","unstructured":"Korzekwa A, Jaroszewski JJ, Bogacki M, Deptula KM, Maslanka TS, Acosta T, Okuda K, Skarzynski DJ (2004) Effects of prostaglandin F2\u03b1and nitric oxide on the secretory function of the bovine luteal cells. J Reprod Dev 50:411\u2013417","journal-title":"J Reprod Dev"},{"key":"5120_CR31","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1262\/jrd.17092","volume":"52","author":"AJ Korzekwa","year":"2006","unstructured":"Korzekwa AJ, Shuko M, Jaroszewski J, Wocawek-Potocka I, Okuda K, Skarzynski DJ (2006) Nitric oxide induces programmed cell dead in the bovine corpus luteum: mechanism of action. J Reprod Dev 52:353\u2013361","journal-title":"J Reprod Dev"},{"key":"5120_CR33","unstructured":"Manov V, Planski V, Popov GS (2018) Histological characteristics of folliculogenesis in murrah water buffaloes during the early postpubertal period. Bulgarian Journal of Veterinary Medicine"},{"key":"5120_CR34","doi-asserted-by":"crossref","unstructured":"Mishra SR (2020) Significance of molecular chaperones and micro RNAs in acquisition of thermo-tolerance in dairy cattle. J Anim Biotechnol 1\u201311","DOI":"10.1080\/10495398.2020.1830788"},{"key":"5120_CR35","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/j.domaniend.2009.04.005","volume":"37","author":"A Miyamoto","year":"2009","unstructured":"Miyamoto A, Shirasuna K, Sasahara K (2009) Local regulation of corpus luteum development and regression in the cow: Impact of angiogenic and vasoactive factors. Domest Anim Endocrinol 37:159\u2013169","journal-title":"Domest Anim Endocrinol"},{"key":"5120_CR36","doi-asserted-by":"crossref","unstructured":"Oh E, Kim JY, Cho Y, An H, Lee N, Joc H, Ban C, Seo JH (2016) Overexpression of angiotensin II type 1 receptor in breast cancer cells induces epithelial\u2013mesenchymal transition and promotes tumor growth and angiogenesis. Biochim Biophys Acta. 1071\u20131081","DOI":"10.1016\/j.bbamcr.2016.03.010"},{"key":"5120_CR37","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1186\/1477-7827-1-95","volume":"1","author":"K Okuda","year":"2003","unstructured":"Okuda K, Sakumoto R (2003) Multiple roles of TNF super family members in corpus luteum function. Reproductive Biology Endocrinol 1:95\u2013105","journal-title":"Reproductive Biology Endocrinol"},{"key":"5120_CR38","first-page":"64","volume":"98","author":"FI Omran","year":"2020","unstructured":"Omran FI, Khalil AA, Fooda TA (2020) Physiological responses and hematological aspects of buffaloes and cows under different climatic conditions in Egypt. Egypt J Agric Res 98:64\u201379","journal-title":"Egypt J Agric Res"},{"key":"5120_CR39","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1016\/j.ygcen.2011.03.001","volume":"171","author":"F Parillo","year":"2011","unstructured":"Parillo F, Catone G, Boiti C, Zerani M (2011) Immunopresence and enzymatic activity of nitric oxide synthases, cyclooxygenases and PGE2-9-ketoreductase and in vitro production of PGF2a, PGE2 and testosterone in the testis of adult and prepubertal alpaca (Lama pacos). Gen Comp Endocrinol 171:381\u2013388","journal-title":"Gen Comp Endocrinol"},{"key":"5120_CR40","doi-asserted-by":"publisher","first-page":"1682","DOI":"10.1002\/jemt.22116","volume":"75","author":"F Parillo","year":"2012","unstructured":"Parillo F, Catone G, Maranesi M, Gobbetti A, Gasparrini B, Russo M, Boiti C, Zerani M (2012) Immunolocalization, gene expression, and enzymatic activity of Cyclooxygenases, prostaglandin e2-9-ketoreductase, and nitric oxide synthases in mediterranean buffalo (bubalus bubalis) corpora lutea during diestrus. Microsc Res Tech 75:1682\u20131690","journal-title":"Microsc Res Tech"},{"key":"5120_CR41","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1111\/jnc.13729","volume":"139","author":"L Planells-Ferrer","year":"2016","unstructured":"Planells-Ferrer L, Urresti J, Coccia E, Galenkamp KM, Calleja-Yag\u00fce I, L\u00f3pez-Soriano J, Carriba P, Barneda-Zahonero B, Segura MF, Comella JX (2016) Fas apoptosis inhibitory molecules: more than death receptor antagonists in the nervous system. J Neurochem 139:11\u201321","journal-title":"J Neurochem"},{"key":"5120_CR42","doi-asserted-by":"publisher","first-page":"9972","DOI":"10.3390\/ijms22189972","volume":"22","author":"E Przygrodzka","year":"2021","unstructured":"Przygrodzka E, Plewes M, Davis JS (2021) Luteinizing hormone regulation of inter-organelle communication and fate of the corpus luteum. Int J Mol Sci 22:9972","journal-title":"Int J Mol Sci"},{"key":"5120_CR43","first-page":"710","volume":"83","author":"HB Rakesh","year":"2013","unstructured":"Rakesh HB, Singh SK, Sharma GC, Jessiehun N, Agarwal SK (2013) Morphological and functional characterization of corpus luteum during different stages of estrous cycle in buffalo. Indian J Anim Sci 83:710\u2013712","journal-title":"Indian J Anim Sci"},{"key":"5120_CR44","first-page":"215","volume":"67","author":"R Rekawiecki","year":"2015","unstructured":"Rekawiecki R, Kowalik MK, Kotwica J (2015) Cloning and expression of progesterone receptor isoforms A and B in bovine corpus luteum. Reprod Fertil Dev 67:215\u2013225","journal-title":"Reprod Fertil Dev"},{"key":"5120_CR45","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1016\/j.anireprosci.2017.05.011","volume":"183","author":"R Rekawiecki","year":"2017","unstructured":"Rekawiecki R, Kowalik MK, Kotwica J (2017) The expression of progesterone receptor coregulators mRNA and protein in corpus luteum and endometrium of cows during the estrous cycle. Anim Reprod Sci 183:102\u2013109","journal-title":"Anim Reprod Sci"},{"key":"5120_CR46","first-page":"365","volume":"132","author":"S Rozen","year":"2000","unstructured":"Rozen S, Skaletsky H (2000) Users Primer3 on the WWW for General and for Biologist Programmers. Bioinf Methods Protocols Part Methods Mol Biology 132:365\u2013386","journal-title":"Bioinf Methods Protocols Part Methods Mol Biology"},{"key":"5120_CR47","doi-asserted-by":"publisher","first-page":"988","DOI":"10.1111\/j.1439-0531.2009.01472.x","volume":"45","author":"M Russo","year":"2010","unstructured":"Russo M, Vecchio D, Neglia G (2010) Corpus luteum function and pregnancy outcome in buffaloes during the transition period from breeding to nonbreeding season. Reprod Domest Anim 45:988\u2013991","journal-title":"Reprod Domest Anim"},{"key":"5120_CR48","doi-asserted-by":"publisher","first-page":"2271","DOI":"10.1007\/s10616-016-0022-y","volume":"68","author":"EM Sadeesh","year":"2016","unstructured":"Sadeesh EM, Sikka P, Balhara AK, Balhara S (2016) Developmental competence and expression profile of genes in buffalo (Bubalus bubalis) oocytes and embryos collected under different environmental stress. Cytotechnology 68:2271\u20132285","journal-title":"Cytotechnology"},{"key":"5120_CR49","doi-asserted-by":"crossref","unstructured":"Sboros V (2014) The ovine corpus luteum angiogenesis model: a tool for developing imaging technology. Annu Int Conf IEEE Eng Med Biol Soc 4280\u20134282","DOI":"10.1109\/EMBC.2014.6944570"},{"key":"5120_CR50","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1016\/j.domaniend.2012.03.003","volume":"43","author":"K Shirasuna","year":"2012","unstructured":"Shirasuna K, Akabane Y, Beindorff N, Nagai K, Sasaki M, Shimizu T, Bollwein H, Meidan R, Miyamoto A (2012) Expression of prostaglandin F 2\u03b1 (PGF 2\u03b1) receptor and its isoforms in the bovine corpus luteum during the estrous cycle and PGF 2\u03b1-induced luteolysis. Domest Anim Endocrin 43:227\u2013238","journal-title":"Domest Anim Endocrin"},{"key":"5120_CR52","doi-asserted-by":"publisher","first-page":"1674","DOI":"10.1095\/biolreprod.102.008573","volume":"68","author":"DJ Skarzynski","year":"2003","unstructured":"Skarzynski DJ, Jaroszewski JJ, Bah MM, Deptula KM, Barszczewska B, Gawronska B, Hansel W (2003) Administration of a nitric oxide synthase inhibitor counteracts prostaglandin F2- induced luteolysis in cattle. Biol Reprod 68:1674\u20131681","journal-title":"Biol Reprod"},{"key":"5120_CR51","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1016\/j.domaniend.2005.02.005","volume":"29","author":"DJ Skarzynski","year":"2005","unstructured":"Skarzynski DJ, Jaroszewski JJ, Okuda K (2005) Role of tumor necrosis factor \u2013\u03b1 and nitric oxide in luteolysis in cattle. Domest Anim Endocrinol 29:340\u2013346","journal-title":"Domest Anim Endocrinol"},{"key":"5120_CR53","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1111\/rda.12203","volume":"48","author":"DJ Skarzynski","year":"2013","unstructured":"Skarzynski DJ, Piotrowska-Tomala KK, Lukasik K, Galvao A, Farberov S, Zalman Y, Meidan R (2013) Growth and regression in bovine corpora Lutea: regulation by local survival and death pathways. Reprod Domest Anim 48:25\u201337","journal-title":"Reprod Domest Anim"},{"key":"5120_CR54","doi-asserted-by":"publisher","first-page":"532","DOI":"10.1007\/s11250-021-02977-9","volume":"53","author":"ASA Sosa","year":"2021","unstructured":"Sosa ASA, Ibrahim S, Mahmoud KGh M, El-Baghdady YR, Nawito MF, Abdo MSS, Ayoub MM (2021) Dynamic patterns of expressed genes in granulosa cells during follicular and luteal stages in Egyptian buffaloes. Trop Anim Health Prod 53:532","journal-title":"Trop Anim Health Prod"},{"key":"5120_CR55","doi-asserted-by":"publisher","first-page":"977","DOI":"10.1262\/jrd.19047","volume":"53","author":"N Sugino","year":"2007","unstructured":"Sugino N, Okuda K (2007) Species related differences in the mechanism of apoptosis during structural luteolysis. J Reprod Dev 53:977\u2013986","journal-title":"J Reprod Dev"},{"key":"5120_CR56","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1186\/1477-7827-5-16","volume":"5","author":"PK Tithof","year":"2007","unstructured":"Tithof PK, Roberts MP, Guan W, Elgayyar M, Godkin JD (2007) Distinct phospholipase A2 18 enzymes regulate prostaglandin E2 and F2alpha production by bovine endometrial epithelial 19 cells. Reprod Biol Endocrinol 5:16\u201328","journal-title":"Reprod Biol Endocrinol"},{"key":"5120_CR57","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1016\/j.theriogenology.2020.09.015","volume":"158","author":"E Trevisol","year":"2020","unstructured":"Trevisol E, Mogollon,Garc\u00eda HD, Ackermann CL, Lacerda W, Pires RML, Laufer-Amorin R, Carvalho RF, Franchi FF, Castilho ACS, Rizzoto G, Kastelic JP, Ferreira JCP (2020) Partial luteolysis during early diestrus in cattle down regulates VEGFA expression and reduces large luteal cell and corpus luteum sizes and plasma progesterone concentration. Theriogenology 158:188\u2013195","journal-title":"Theriogenology"},{"key":"5120_CR58","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1007\/s12192-021-01209-1","volume":"26","author":"SIU Umar","year":"2021","unstructured":"Umar SIU, Konwar D, Khan A, Bhat MA, Javid F, Jeelani R, Nabi B, Najar AA, Kumar D, Brahma B (2021) Delineation of temperature-humidity index (THI) as indicator of heat stress in riverine buffaloes (Bubalusbubalis) of a sub-tropical Indian region. Cell Stress Chaperones 26:657\u2013669","journal-title":"Cell Stress Chaperones"},{"key":"5120_CR59","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.theriogenology.2017.09.008","volume":"105","author":"AD Verma","year":"2018","unstructured":"Verma AD, Panigrahi M, Baba NA, Sulabh S, Sadam A, Parida S, Narayanan K, Sonwane AA, Bhushan B (2018) Differential expression of ten candidate genes regulating prostaglandin action in reproductive tissues of buffalo during estrous cycle and pregnancy. Theriogenology 105:7\u201314","journal-title":"Theriogenology"},{"key":"5120_CR60","doi-asserted-by":"publisher","first-page":"1429","DOI":"10.1097\/00004872-200308000-00001","volume":"21","author":"M Volpe","year":"2003","unstructured":"Volpe M, Musumecia B, Paolisb PD, Savoiaa C, Morganti A (2003) Angiotensin II AT2 receptor subtype: an uprising frontier in cardiovascular disease? J Hypertens 21:1429\u20131443","journal-title":"J Hypertens"},{"key":"5120_CR61","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/j.prostaglandins.2004.06.002","volume":"74","author":"YS Weems","year":"2004","unstructured":"Weems YS, Randel RD, Tatman S, Lewis AW, Neuendorff DA, Weems CW (2004) Effects of estrous synchronization on response to nitric oxide donors, nitric oxide synthase inhibitors, and endothelin-1 in vitro. Prostaglandins Other Lipid Mediat 74:45\u201359","journal-title":"Prostaglandins Other Lipid Mediat"},{"key":"5120_CR62","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/j.theriogenology.2020.10.010","volume":"159","author":"P Witek","year":"2021","unstructured":"Witek P, Grzesiak M, Kotula-Balak M, Koziorowski M, Slomczynska M, Knapczyk-Stwora K (2021) Effect of neonatal exposure to endocrine-active compounds on epigenetic regulation of gene expression in corpus luteum of gilts. Theriogenology 159:45\u201352","journal-title":"Theriogenology"},{"key":"5120_CR63","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1530\/JOE-15-0521","volume":"230","author":"YL Yang","year":"2016","unstructured":"Yang YL, Ren LR, Sun LF, Huang C, Xiao TX (2016) The role of GPR1 signaling in mice 388 corpus luteum. J Endocrinol 230:55\u201365","journal-title":"J Endocrinol"},{"key":"5120_CR64","doi-asserted-by":"publisher","first-page":"e841","DOI":"10.1371\/journal.pone.0084186","volume":"8","author":"S Yoshioka","year":"2013","unstructured":"Yoshioka S, Abem H, Sakumoto R, Okuda K (2013) Proliferation of luteal steroidogenic cells in cattle. PLoS ONE 8:e841\u2013860","journal-title":"PLoS ONE"}],"container-title":["Tropical Animal Health and Production"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11250-026-05120-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11250-026-05120-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11250-026-05120-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T18:18:27Z","timestamp":1785521907000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11250-026-05120-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,22]]},"references-count":64,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["5120"],"URL":"https:\/\/doi.org\/10.1007\/s11250-026-05120-8","relation":{},"ISSN":["0049-4747","1573-7438"],"issn-type":[{"value":"0049-4747","type":"print"},{"value":"1573-7438","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,22]]},"assertion":[{"value":"25 July 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 May 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 June 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The study is approved ethically from the Veterinary Medicine Cairo University Institutional Animal Care and Use Committee (Vet- CU- IACUC) with approval number (Vet CU 12\/10\/2021\/346). All methods were carried out in accordance with relevant guidelines and regulations.","order":1,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","label":"Consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":3,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they don\u2019t have any conflict of interest.","order":4,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"368"}}