{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T08:58:13Z","timestamp":1773392293385,"version":"3.50.1"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2014,11,16]],"date-time":"2014-11-16T00:00:00Z","timestamp":1416096000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Urol Nephrol"],"published-print":{"date-parts":[[2015,3]]},"DOI":"10.1007\/s11255-014-0876-x","type":"journal-article","created":{"date-parts":[[2014,11,15]],"date-time":"2014-11-15T13:53:37Z","timestamp":1416059617000},"page":"527-535","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Efficacy and safety of lanthanum carbonate versus calcium-based phosphate binders in patients with chronic kidney disease: a systematic review and meta-analysis"],"prefix":"10.1007","volume":"47","author":[{"given":"Chun-Juan","family":"Zhai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao-Wei","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,11,16]]},"reference":[{"issue":"9811","key":"876_CR1","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0140-6736(11)60178-5","volume":"379","author":"AS Levey","year":"2012","unstructured":"Levey AS, Coresh J (2012) Chronic kidney disease. Lancet 379(9811):165\u2013180. doi: 10.1016\/S0140-6736(11)60178-5","journal-title":"Lancet"},{"issue":"Suppl 1","key":"876_CR2","doi-asserted-by":"crossref","first-page":"S102","DOI":"10.2215\/CJN.04800709","volume":"4","author":"I Bhan","year":"2009","unstructured":"Bhan I, Thadhani R (2009) Vascular calcification and ESRD: a hard target. Clin J Am Soc Nephrol 4(Suppl 1):S102\u2013S105. doi: 10.2215\/CJN.04800709","journal-title":"Clin J Am Soc Nephrol"},{"issue":"11","key":"876_CR3","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.1038\/sj.ki.5000414","volume":"69","author":"S Moe","year":"2006","unstructured":"Moe S, Drueke T, Cunningham J, Goodman W, Martin K, Olgaard K, Ott S, Sprague S, Lameire N, Eknoyan G, Kidney Disease: Improving Global O (2006) Definition, evaluation, and classification of renal osteodystrophy: a position statement from kidney disease: improving global outcomes (KDIGO). Kidney Int 69(11):1945\u20131953. doi: 10.1038\/sj.ki.5000414","journal-title":"Kidney Int"},{"issue":"8","key":"876_CR4","doi-asserted-by":"crossref","first-page":"2208","DOI":"10.1097\/01.ASN.0000133041.27682.A2","volume":"15","author":"GA Block","year":"2004","unstructured":"Block GA, Klassen PS, Lazarus JM, Ofsthun N, Lowrie EG, Chertow GM (2004) Mineral metabolism, mortality, and morbidity in maintenance hemodialysis. J Am Soc Nephrol : JASN 15(8):2208\u20132218. doi: 10.1097\/01.ASN.0000133041.27682.A2","journal-title":"J Am Soc Nephrol : JASN"},{"issue":"3","key":"876_CR5","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1053\/j.ajkd.2008.03.020","volume":"52","author":"F Tentori","year":"2008","unstructured":"Tentori F, Blayney MJ, Albert JM, Gillespie BW, Kerr PG, Bommer J, Young EW, Akizawa T, Akiba T, Pisoni RL, Robinson BM, Port FK (2008) Mortality risk for dialysis patients with different levels of serum calcium, phosphorus, and PTH: the Dialysis Outcomes and Practice Patterns Study (DOPPS). Am J Kidney Dis 52(3):519\u2013530. doi: 10.1053\/j.ajkd.2008.03.020","journal-title":"Am J Kidney Dis"},{"issue":"6","key":"876_CR6","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1007\/s10157-011-0517-y","volume":"15","author":"M Ohya","year":"2011","unstructured":"Ohya M, Otani H, Kimura K, Saika Y, Fujii R, Yukawa S, Shigematsu T (2011) Vascular calcification estimated by aortic calcification area index is a significant predictive parameter of cardiovascular mortality in hemodialysis patients. Clin Exp Nephrol 15(6):877\u2013883. doi: 10.1007\/s10157-011-0517-y","journal-title":"Clin Exp Nephrol"},{"issue":"9","key":"876_CR7","doi-asserted-by":"crossref","first-page":"553","DOI":"10.2165\/00003088-200847090-00001","volume":"47","author":"SJ Damment","year":"2008","unstructured":"Damment SJ, Pennick M (2008) Clinical pharmacokinetics of the phosphate binder lanthanum carbonate. Clin Pharmacokinet 47(9):553\u2013563","journal-title":"Clin Pharmacokinet"},{"issue":"1","key":"876_CR8","doi-asserted-by":"crossref","first-page":"c15","DOI":"10.1159\/000149239","volume":"110","author":"Hutchison AJ, Barnett ME, Krause R, Kwan JT, Siami GA, Group SPDLS","year":"2008","unstructured":"Hutchison AJ, Barnett ME, Krause R, Kwan JT, Siami GA, Group SPDLS (2008) Long-term efficacy and safety profile of lanthanum carbonate: results for up to 6\u00a0years of treatment. Nephron Clin Pract 110(1):c15\u2013c23. doi: 10.1159\/000149239","journal-title":"Nephron Clin Pract"},{"issue":"1","key":"876_CR9","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1111\/j.1744-9987.2007.00541.x","volume":"12","author":"T Shigematsu","year":"2008","unstructured":"Shigematsu T, Lanthanum Carbonate Research G (2008) Lanthanum carbonate effectively controls serum phosphate without affecting serum calcium levels in patients undergoing hemodialysis. Ther Apher Dial 12(1):55\u201361. doi: 10.1111\/j.1744-9987.2007.00541.x","journal-title":"Ther Apher Dial"},{"issue":"6","key":"876_CR10","first-page":"428","volume":"64","author":"AJ Freemont","year":"2005","unstructured":"Freemont AJ, Hoyland JA, Denton J, SPDSG Lanthanum Carbonate (2005) The effects of lanthanum carbonate and calcium carbonate on bone abnormalities in patients with end-stage renal disease. Clin Nephrol 64(6):428\u2013437","journal-title":"Clin Nephrol"},{"issue":"1","key":"876_CR11","doi-asserted-by":"crossref","first-page":"c8","DOI":"10.1159\/000084653","volume":"100","author":"AJ Hutchison","year":"2005","unstructured":"Hutchison AJ, Maes B, Vanwalleghem J, Asmus G, Mohamed E, Schmieder R, Backs W, Jamar R, Vosskuhler A (2005) Efficacy, tolerability, and safety of lanthanum carbonate in hyperphosphatemia: a 6-month, randomized, comparative trial versus calcium carbonate. Nephron Clin Pract 100(1):c8\u2013c19","journal-title":"Nephron Clin Pract"},{"issue":"2","key":"876_CR12","doi-asserted-by":"crossref","first-page":"136","DOI":"10.5414\/CN107362","volume":"79","author":"YK Lee","year":"2013","unstructured":"Lee YK, Choi HY, Shin SK, Lee HY (2013) Effect of lanthanum carbonate on phosphate control in continuous ambulatory peritoneal dialysis patients in Korea: a randomized prospective study. Clin Nephrol 79(2):136\u2013142. doi: 10.5414\/cn107362","journal-title":"Clin Nephrol"},{"issue":"5","key":"876_CR13","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1177\/1074248413486355","volume":"18","author":"T Ohtake","year":"2013","unstructured":"Ohtake T, Kobayashi S, Oka M, Furuya R, Iwagami M, Tsutsumi D, Mochida Y, Maesato K, Ishioka K, Moriya H, Hidaka S (2013) Lanthanum carbonate delays progression of coronary artery calcification compared with calcium-based phosphate binders in patients on hemodialysis: a pilot study. J Cardiovasc Pharmacol Ther 18(5):439\u2013446","journal-title":"J Cardiovasc Pharmacol Ther"},{"issue":"4","key":"876_CR14","doi-asserted-by":"crossref","first-page":"187","DOI":"10.4103\/0253-7613.56074","volume":"41","author":"PT Scaria","year":"2009","unstructured":"Scaria PT, Gangadhar R, Pisharody R (2009) Effect of lanthanum carbonate and calcium acetate in the treatment of hyperphosphatemia in patients of chronic kidney disease. Indian J Pharmacol 41(4):187\u2013191. doi: 10.4103\/0253-7613.56074","journal-title":"Indian J Pharmacol"},{"issue":"5","key":"876_CR15","doi-asserted-by":"crossref","first-page":"404","DOI":"10.5414\/CNP70404","volume":"70","author":"T Shigematsu","year":"2008","unstructured":"Shigematsu T, Sakai T, Kono T, Kimura Y, Takuma Y, Tsuruta Y, Mori Y, Taki M, Moriishi M, Minakuchi J, Obayashi S, Miyake S, Emoto H, Furuhashi M, Tsujimoto Y, Arisaka H, Ishizaki M, Shimoyama H, Kim S, Hirose S, Kurosawa A, Matsui N, Nakazawa R, Watanabe T, Kabaya T, Tanaka Y, Takahashi T, Ozawa T, Nakamura K, Nishioka M, Higashi H, Koga N (2008) Multicenter prospective randomized, double-blind comparative study between lanthanum carbonate and calcium carbonate as phosphate binders in Japanese hemodialysis, patients with hyperphosphatemia. Clin Nephrol 70(5):404\u2013410","journal-title":"Clin Nephrol"},{"issue":"1","key":"876_CR16","doi-asserted-by":"crossref","first-page":"17","DOI":"10.5414\/CN107764","volume":"80","author":"S Soriano","year":"2013","unstructured":"Soriano S, Ojeda R, Rodriguez M, Almaden Y, Rodriguez M, Martin-Malo A, Aljama P (2013) The effect of phosphate binders, calcium and lanthanum carbonate on FGF23 levels in chronic kidney disease patients. Clin Nephrol 80(1):17\u201322. doi: 10.5414\/cn107764","journal-title":"Clin Nephrol"},{"issue":"8","key":"876_CR17","doi-asserted-by":"crossref","first-page":"2217","DOI":"10.1093\/ndt\/gfl146","volume":"21","author":"GB Spasovski","year":"2006","unstructured":"Spasovski GB, Sikole A, Gelev S, Masin-Spasovska J, Freemont T, Webster I, Gill M, Jones C, De Broe ME, D\u2019Haese PC (2006) Evolution of bone and plasma concentration of lanthanum in dialysis patients before, during 1\u00a0year of treatment with lanthanum carbonate and after 2\u00a0years of follow-up. Nephrol Dial Transplant 21(8):2217\u20132224. doi: 10.1093\/ndt\/gfl146","journal-title":"Nephrol Dial Transplant"},{"issue":"3","key":"876_CR18","doi-asserted-by":"crossref","first-page":"216","DOI":"10.5414\/CN107257","volume":"78","author":"T Toida","year":"2012","unstructured":"Toida T, Fukudome K, Fujimoto S, Yamada K, Sato Y, Chiyotanda S, Kitamura K (2012) Effect of lanthanum carbonate vs. calcium carbonate on serum calcium in hemodialysis patients: a crossover study. Clin Nephrol 78(3):216\u2013223","journal-title":"Clin Nephrol"},{"issue":"3","key":"876_CR19","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1111\/j.1440-1797.2010.01412.x","volume":"16","author":"ND Toussaint","year":"2011","unstructured":"Toussaint ND, Lau KK, Polkinghorne KR, Kerr PG (2011) Attenuation of aortic calcification with lanthanum carbonate versus calcium-based phosphate binders in haemodialysis: a pilot randomized controlled trial. Nephrology 16(3):290\u2013298","journal-title":"Nephrology"},{"key":"876_CR20","doi-asserted-by":"crossref","unstructured":"Wada K, Wada Y (2014) Evaluation of aortic calcification with lanthanum carbonate vs. calcium-based phosphate binders in maintenance hemodialysis patients with type 2 diabetes mellitus: an open-label randomized controlled trial. Ther Apher Dial. doi: 10.1111\/1744-9987.12153","DOI":"10.1111\/1744-9987.12153"},{"issue":"9900","key":"876_CR21","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1016\/S0140-6736(13)60897-1","volume":"382","author":"SA Jamal","year":"2013","unstructured":"Jamal SA, Vandermeer B, Raggi P, Mendelssohn DC, Chatterley T, Dorgan M, Lok CE, Fitchett D, Tsuyuki RT (2013) Effect of calcium-based versus non-calcium-based phosphate binders on mortality in patients with chronic kidney disease: an updated systematic review and meta-analysis. Lancet 382(9900):1268\u20131277. doi: 10.1016\/S0140-6736(13)60897-1","journal-title":"Lancet"},{"key":"876_CR22","doi-asserted-by":"crossref","unstructured":"Navaneethan SD, Palmer SC, Craig JC, Elder GJ, Strippoli GFM (2009) Benefits and harms of phosphate binders in CKD: a systematic review of randomized controlled trials. Am J Kidney Dis 54(4):619\u2013637","DOI":"10.1053\/j.ajkd.2009.06.004"},{"issue":"1","key":"876_CR23","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1186\/1471-2369-14-226","volume":"14","author":"C Zhang","year":"2013","unstructured":"Zhang C, Wen J, Li Z, Fan J (2013) Efficacy and safety of lanthanum carbonate on chronic kidney disease\u2013mineral and bone disorder in dialysis patients: a systematic review. BMC Nephrol 14(1):226. doi: 10.1186\/1471-2369-14-226","journal-title":"BMC Nephrol"},{"issue":"10","key":"876_CR24","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.3109\/0886022X.2013.828365","volume":"35","author":"H Guo","year":"2013","unstructured":"Guo H, Zhang X, Tang S, Zhang S (2013) Effects and safety of lanthanum carbonate in end stage renal disease patients with hyperphosphatemia: a meta-analysis\u2014system review of lanthanum carbonate. Ren Fail 35(10):1455\u20131464. doi: 10.3109\/0886022X.2013.828365","journal-title":"Ren Fail"},{"issue":"4 Suppl 3","key":"876_CR25","first-page":"S1","volume":"42","author":"National Kidney Foundation","year":"2003","unstructured":"National Kidney Foundation (2003) K\/DOQI clinical practice guidelines for bone metabolism and disease in chronic kidney disease. Am J Kidney Dis 42(4 Suppl 3):S1\u2013S201","journal-title":"Am J Kidney Dis"},{"issue":"1","key":"876_CR26","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1111\/j.1524-4733.2006.00142.x","volume":"10","author":"A Brennan","year":"2007","unstructured":"Brennan A, Akehurst R, Davis S, Sakai H, Abbott V (2007) The cost-effectiveness of lanthanum carbonate in the treatment of hyperphosphatemia in patients with end-stage renal disease. Value Health 10(1):32\u201341. doi: 10.1111\/j.1524-4733.2006.00142.x","journal-title":"Value Health"},{"issue":"6","key":"876_CR27","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.2215\/CJN.08841010","volume":"6","author":"S Goto","year":"2011","unstructured":"Goto S, Komaba H, Moriwaki K, Fujimori A, Shibuya K, Nishioka M, Kim JI, Yoshiya K, Shin J, Hasegawa H, Taniguchi M, Fujii H, Nishi S, Kamae I, Fukagawa M (2011) Clinical efficacy and cost-effectiveness of lanthanum carbonate as second-line therapy in hemodialysis patients in Japan. Clin J Am Soc Nephrol 6(6):1375\u20131384. doi: 10.2215\/CJN.08841010","journal-title":"Clin J Am Soc Nephrol"},{"issue":"8","key":"876_CR28","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1016\/j.jval.2011.05.043","volume":"14","author":"H Park","year":"2011","unstructured":"Park H, Rascati KL, Keith MS, Hodgkins P, Smyth M, Goldsmith D, Akehurst R (2011) Cost-effectiveness of lanthanum carbonate versus sevelamer hydrochloride for the treatment of hyperphosphatemia in patients with end-stage renal disease: a US payer perspective. Value Health 14(8):1002\u20131009. doi: 10.1016\/j.jval.2011.05.043","journal-title":"Value Health"},{"issue":"6","key":"876_CR29","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1016\/j.jval.2011.05.005","volume":"14","author":"S Vegter","year":"2011","unstructured":"Vegter S, Tolley K, Keith MS, Postma MJ (2011) Cost-effectiveness of lanthanum carbonate in the treatment of hyperphosphatemia in chronic kidney disease before and during dialysis. Value Health 14(6):852\u2013858. doi: 10.1016\/j.jval.2011.05.005","journal-title":"Value Health"}],"container-title":["International Urology and Nephrology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11255-014-0876-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11255-014-0876-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11255-014-0876-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T11:59:25Z","timestamp":1559390365000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11255-014-0876-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11,16]]},"references-count":29,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,3]]}},"alternative-id":["876"],"URL":"https:\/\/doi.org\/10.1007\/s11255-014-0876-x","relation":{},"ISSN":["0301-1623","1573-2584"],"issn-type":[{"value":"0301-1623","type":"print"},{"value":"1573-2584","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,11,16]]}}}