{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T01:47:27Z","timestamp":1776995247951,"version":"3.51.4"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2019,3,19]],"date-time":"2019-03-19T00:00:00Z","timestamp":1552953600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Sciences Foundation of China","doi-asserted-by":"crossref","award":["81260120"],"award-info":[{"award-number":["81260120"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Sciences Foundation of China","doi-asserted-by":"crossref","award":["81500586"],"award-info":[{"award-number":["81500586"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Urol Nephrol"],"published-print":{"date-parts":[[2019,5]]},"DOI":"10.1007\/s11255-019-02122-4","type":"journal-article","created":{"date-parts":[[2019,4,17]],"date-time":"2019-04-17T12:42:21Z","timestamp":1555504941000},"page":"889-896","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["MiR-200a ameliorates peritoneal fibrosis and functional deterioration in a rat model of peritoneal dialysis"],"prefix":"10.1007","volume":"51","author":[{"given":"Xin","family":"Wei","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi","family":"Bao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaojiang","family":"Zhan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guojun","family":"Hao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qinkai","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,3,19]]},"reference":[{"key":"2122_CR1","doi-asserted-by":"publisher","first-page":"1016","DOI":"10.1038\/ki.2014.224","volume":"86","author":"VA Kumar","year":"2014","unstructured":"Kumar VA, Sidell MA, Jones JP, Vonesh EF (2014) Survival of propensity matched incident peritoneal and hemodialysis patients in a United States health care system. Kidney Int 86:1016\u20131022","journal-title":"Kidney Int"},{"key":"2122_CR2","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1046\/j.1523-1755.1999.00264.x","volume":"55","author":"RT Krediet","year":"1999","unstructured":"Krediet RT (1999) The peritoneal membrane in chronic peritoneal dialysis. Kidney Int 55:341\u2013356","journal-title":"Kidney Int"},{"key":"2122_CR3","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1038\/nrneph.2013.99","volume":"9","author":"RT Krediet","year":"2013","unstructured":"Krediet RT, Struijk DG (2013) Peritoneal changes in patients on long-term peritoneal dialysis. Nat Rev Nephrol 9:419\u2013429","journal-title":"Nat Rev Nephrol"},{"issue":"Suppl 4","key":"2122_CR4","doi-asserted-by":"crossref","first-page":"S83","DOI":"10.1177\/089686080502504S12","volume":"25","author":"Y Kawaguchi","year":"2005","unstructured":"Kawaguchi Y, Saito A, Kawanishi H et al (2005) Recommendations on the management of encapsulating peritoneal sclerosis in Japan, 2005: diagnosis, predictive markers, treatment, and preventive measures. Perit Dial Int 25(Suppl 4):S83\u2013S95","journal-title":"Perit Dial Int"},{"key":"2122_CR5","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1056\/NEJMoa020809","volume":"348","author":"M Yanez-Mo","year":"2003","unstructured":"Yanez-Mo M, Lara-Pezzi E, Selgas R et al (2003) Peritoneal dialysis and epithelial-to-mesenchymal transition of mesothelial cells. N Engl J Med 348:403\u2013413","journal-title":"N Engl J Med"},{"key":"2122_CR6","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/j.matbio.2009.10.004","volume":"29","author":"P Patel","year":"2010","unstructured":"Patel P, West-Mays J, Kolb M, Rodrigues JC, Hoff CM, Margetts PJ (2010) Platelet derived growth factor B and epithelial mesenchymal transition of peritoneal mesothelial cells. Matrix Biol 29:97\u2013106","journal-title":"Matrix Biol"},{"key":"2122_CR7","doi-asserted-by":"publisher","first-page":"e112050","DOI":"10.1371\/journal.pone.0112050","volume":"9","author":"AC Abrahams","year":"2014","unstructured":"Abrahams AC, Habib SM, Dendooven A et al (2014) Patients with encapsulating peritoneal sclerosis have increased peritoneal expression of connective tissue growth factor (CCN2), transforming growth factor-beta1, and vascular endothelial growth factor. PLoS ONE 9:e112050","journal-title":"PLoS ONE"},{"key":"2122_CR8","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1093\/ndt\/gfp480","volume":"25","author":"X Wang","year":"2010","unstructured":"Wang X, Nie J, Jia Z et al (2010) Impaired TGF-beta signalling enhances peritoneal inflammation induced by E. coli in rats. Nephrol Dial Transplant 25:399\u2013412","journal-title":"Nephrol Dial Transplant"},{"key":"2122_CR9","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1038\/nrc2131","volume":"7","author":"H Peinado","year":"2007","unstructured":"Peinado H, Olmeda D, Cano A. Snail (2007) Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nat Rev Cancer 7:415\u2013428","journal-title":"Nat Rev Cancer"},{"key":"2122_CR10","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1038\/35000025","volume":"2","author":"A Cano","year":"2000","unstructured":"Cano A, Perez-Moreno MA, Rodrigo I et al (2000) The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nat Cell Biol 2:76\u201383","journal-title":"Nat Cell Biol"},{"key":"2122_CR11","doi-asserted-by":"publisher","first-page":"1280","DOI":"10.1093\/emboj\/18.5.1280","volume":"18","author":"X Yang","year":"1999","unstructured":"Yang X, Letterio JJ, Lechleider RJ et al (1999) Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta. Embo J 18:1280\u20131291","journal-title":"Embo J"},{"key":"2122_CR12","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1038\/359693a0","volume":"359","author":"MM Shull","year":"1992","unstructured":"Shull MM, Ormsby I, Kier AB et al (1992) Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease. Nature 359:693\u2013699","journal-title":"Nature"},{"key":"2122_CR13","doi-asserted-by":"publisher","first-page":"484","DOI":"10.1016\/j.ajpath.2011.10.005","volume":"180","author":"S Yang","year":"2012","unstructured":"Yang S, Banerjee S, de Freitas A et al (2012) Participation of miR-200 in pulmonary fibrosis. Am J Pathol 180:484\u2013493","journal-title":"Am J Pathol"},{"key":"2122_CR14","doi-asserted-by":"publisher","first-page":"F369","DOI":"10.1152\/ajprenal.00268.2011","volume":"302","author":"M Xiong","year":"2012","unstructured":"Xiong M, Jiang L, Zhou Y et al (2012) The miR-200 family regulates TGF-beta1-induced renal tubular epithelial to mesenchymal transition through Smad pathway by targeting ZEB1 and ZEB2 expression. Am J Physiol Renal Physiol 302:F369\u2013F379","journal-title":"Am J Physiol Renal Physiol"},{"key":"2122_CR15","doi-asserted-by":"publisher","first-page":"F1087","DOI":"10.1152\/ajprenal.00566.2016","volume":"314","author":"R Guo","year":"2018","unstructured":"Guo R, Hao G, Bao Y et al (2018) MiR-200a negatively regulates TGF-beta1-induced epithelial-mesenchymal transition of peritoneal mesothelial cells by targeting ZEB1\/2 expression. Am J Physiol Renal Physiol 314:F1087\u2013F1095","journal-title":"Am J Physiol Renal Physiol"},{"key":"2122_CR16","doi-asserted-by":"publisher","first-page":"1336","DOI":"10.1038\/sj.ki.5002533","volume":"72","author":"J Nie","year":"2007","unstructured":"Nie J, Dou X, Hao W et al (2007) Smad7 gene transfer inhibits peritoneal fibrosis. Kidney int 72:1336\u20131344","journal-title":"Kidney int"},{"key":"2122_CR17","doi-asserted-by":"publisher","first-page":"978","DOI":"10.1038\/labinvest.2014.91","volume":"94","author":"JW Yu","year":"2014","unstructured":"Yu JW, Duan WJ, Huang XR, Meng XM, Yu XQ, Lan HY (2014) MicroRNA-29b inhibits peritoneal fibrosis in a mouse model of peritoneal dialysis. Lab Invest 94:978\u2013990","journal-title":"Lab Invest"},{"key":"2122_CR18","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1038\/nm.3026","volume":"19","author":"X Wang","year":"2013","unstructured":"Wang X, Guo B, Li Q et al (2013) miR-214 targets ATF4 to inhibit bone formation. Nat Med 19:93\u2013100","journal-title":"Nat Med"},{"key":"2122_CR19","doi-asserted-by":"publisher","first-page":"808","DOI":"10.1016\/j.ajpath.2013.05.019","volume":"183","author":"Q Zhou","year":"2013","unstructured":"Zhou Q, Yang M, Lan H, Yu X (2013) miR-30a negatively regulates TGF-beta1-induced epithelial-mesenchymal transition and peritoneal fibrosis by targeting Snai1. Am J Pathol 183:808\u2013819","journal-title":"Am J Pathol"},{"key":"2122_CR20","doi-asserted-by":"publisher","first-page":"842","DOI":"10.1038\/mt.2013.235","volume":"22","author":"HY Chen","year":"2014","unstructured":"Chen HY, Zhong X, Huang XR et al (2014) MicroRNA-29b inhibits diabetic nephropathy in db\/db mice. Mol Ther 22:842\u2013853","journal-title":"Mol Ther"},{"key":"2122_CR21","doi-asserted-by":"publisher","first-page":"1462","DOI":"10.1681\/ASN.2010121308","volume":"22","author":"W Qin","year":"2011","unstructured":"Qin W, Chung AC, Huang XR et al (2011) TGF-beta\/Smad3 signaling promotes renal fibrosis by inhibiting miR-29. J Am Soc Nephrol 22:1462\u20131474","journal-title":"J Am Soc Nephrol"},{"key":"2122_CR22","doi-asserted-by":"crossref","first-page":"121","DOI":"10.3747\/pdi.2010.00041","volume":"31","author":"Z Jiang","year":"2011","unstructured":"Jiang Z, Yu X (2011) Advancing the use and quality of peritoneal dialysis by developing a peritoneal dialysis satellite center program. Perit Dial Int 31:121\u2013126","journal-title":"Perit Dial Int"},{"key":"2122_CR23","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1681\/ASN.V132470","volume":"13","author":"JD Williams","year":"2002","unstructured":"Williams JD, Craig KJ, Topley N et al (2002) Morphologic changes in the peritoneal membrane of patients with renal disease. J Am Soc Nephrol 13:470\u2013479","journal-title":"J Am Soc Nephrol"},{"key":"2122_CR24","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.trsl.2015.10.009","volume":"169","author":"Y Morishita","year":"2016","unstructured":"Morishita Y, Yoshizawa H, Watanabe M et al (2016) MicroRNA expression profiling in peritoneal fibrosis. Transl res 169:47\u201366","journal-title":"Transl res"},{"key":"2122_CR25","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1007\/s00467-011-1945-3","volume":"27","author":"G Aubertin","year":"2012","unstructured":"Aubertin G, Choquet P, Dheu C et al (2012) The impact of dialysis solution biocompatibility on ultrafiltration and on free water transport in rats. Pediatr Nephrol 27:131\u2013138","journal-title":"Pediatr Nephrol"},{"key":"2122_CR26","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1007\/s11010-017-2988-y","volume":"431","author":"M Xu","year":"2017","unstructured":"Xu M, Wang G, Zhou H et al (2017) TGF-beta1-miR-200a-PTEN induces epithelial-mesenchymal transition and fibrosis of pancreatic stellate cells. Mol Cell Biochem 431:161\u2013168","journal-title":"Mol Cell Biochem"},{"key":"2122_CR27","doi-asserted-by":"publisher","first-page":"36436","DOI":"10.1038\/srep36436","volume":"6","author":"BL Hu","year":"2016","unstructured":"Hu BL, Shi C, Lei RE et al (2016) Interleukin-22 ameliorates liver fibrosis through miR-200a\/beta-catenin. Sci Rep 6:36436","journal-title":"Sci Rep"},{"key":"2122_CR28","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1007\/s00011-016-1020-4","volume":"66","author":"JJ Yang","year":"2017","unstructured":"Yang JJ, Tao H, Liu LP, Hu W, Deng ZY, Li J (2017) miR-200a controls hepatic stellate cell activation and fibrosis via SIRT1\/Notch1 signal pathway. Inflamm Res 66:341\u2013352","journal-title":"Inflamm Res"}],"container-title":["International Urology and Nephrology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11255-019-02122-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11255-019-02122-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11255-019-02122-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,16]],"date-time":"2022-09-16T04:34:09Z","timestamp":1663302849000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11255-019-02122-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3,19]]},"references-count":28,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,5]]}},"alternative-id":["2122"],"URL":"https:\/\/doi.org\/10.1007\/s11255-019-02122-4","relation":{},"ISSN":["0301-1623","1573-2584"],"issn-type":[{"value":"0301-1623","type":"print"},{"value":"1573-2584","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3,19]]},"assertion":[{"value":"12 July 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 March 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 March 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"No conflicts of interest, financial or otherwise, are declared by the authors.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All applicable international, national, and institutional guidelines for the care and use of animals were followed.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}