{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T23:49:20Z","timestamp":1771026560222,"version":"3.50.1"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,6,7]],"date-time":"2021-06-07T00:00:00Z","timestamp":1623024000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,6,7]],"date-time":"2021-06-07T00:00:00Z","timestamp":1623024000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/100010665","name":"H2020 Marie Sk\u0142odowska-Curie Actions","doi-asserted-by":"publisher","award":["645648"],"award-info":[{"award-number":["645648"]}],"id":[{"id":"10.13039\/100010665","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Urol Nephrol"],"published-print":{"date-parts":[[2022,1]]},"DOI":"10.1007\/s11255-021-02910-x","type":"journal-article","created":{"date-parts":[[2021,6,7]],"date-time":"2021-06-07T20:05:04Z","timestamp":1623096304000},"page":"201-208","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["A single bout of hybrid intradialytic exercise did not affect left-ventricular function in exercise-na\u00efve dialysis patients: a randomized, cross-over trial"],"prefix":"10.1007","volume":"54","author":[{"given":"Stefania S.","family":"Grigoriou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoforos D.","family":"Giannaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keith","family":"George","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christina","family":"Karatzaferi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paris","family":"Zigoulis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theodoros","family":"Eleftheriadis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ioannis","family":"Stefanidis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2462-995X","authenticated-orcid":false,"given":"Giorgos K.","family":"Sakkas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,6,7]]},"reference":[{"issue":"3","key":"2910_CR1","first-page":"99","volume":"3","author":"S Said","year":"2014","unstructured":"Said S, Hernandez GT (2014) The link between chronic kidney disease and cardiovascular disease. J Nephropathol 3(3):99\u2013104","journal-title":"J Nephropathol"},{"issue":"suppl_3","key":"2910_CR2","doi-asserted-by":"publisher","first-page":"iii28","DOI":"10.1093\/ndt\/gfy174","volume":"33","author":"M Cozzolino","year":"2018","unstructured":"Cozzolino M et al (2018) Cardiovascular disease in dialysis patients. Nephrol Dial Transplant 33(suppl_3):iii28\u2013iii34","journal-title":"Nephrol Dial Transplant"},{"key":"2910_CR3","first-page":"56","volume":"28","author":"A Al-Dadah","year":"2012","unstructured":"Al-Dadah A et al (2012) Cardiovascular mortality in dialysis patients. Adv Perit Dial 28:56\u201359","journal-title":"Adv Perit Dial"},{"issue":"7","key":"2910_CR4","doi-asserted-by":"publisher","first-page":"1606","DOI":"10.1681\/ASN.V1071606","volume":"10","author":"PS Parfrey","year":"1999","unstructured":"Parfrey PS, Foley RN (1999) The clinical epidemiology of cardiac disease in chronic renal failure. J Am Soc Nephrol 10(7):1606\u20131615","journal-title":"J Am Soc Nephrol"},{"issue":"8","key":"2910_CR5","first-page":"1402","volume":"32","author":"PA Sarafidis","year":"2017","unstructured":"Sarafidis PA et al (2017) Haemodialysis acutely deteriorates left and right diastolic function and myocardial performance: an effect related to high ultrafiltration volumes? Nephrol Dial Transplant 32(8):1402\u20131409","journal-title":"Nephrol Dial Transplant"},{"issue":"7","key":"2910_CR6","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1080\/08860220802212908","volume":"30","author":"JO Burton","year":"2008","unstructured":"Burton JO et al (2008) Hemodialysis-induced left ventricular dysfunction is associated with an increase in ventricular arrhythmias. Ren Fail 30(7):701\u2013709","journal-title":"Ren Fail"},{"issue":"2","key":"2910_CR7","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1159\/000245634","volume":"29","author":"CW McIntyre","year":"2010","unstructured":"McIntyre CW (2010) Haemodialysis-induced myocardial stunning in chronic kidney disease - a new aspect of cardiovascular disease. Blood Purif 29(2):105\u2013110","journal-title":"Blood Purif"},{"issue":"3","key":"2910_CR8","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1053\/j.ajkd.2009.03.009","volume":"54","author":"EJ Kouidi","year":"2009","unstructured":"Kouidi EJ, Grekas DM, Deligiannis AP (2009) Effects of exercise training on noninvasive cardiac measures in patients undergoing long-term hemodialysis: a randomized controlled trial. Am J Kidney Dis 54(3):511\u2013521","journal-title":"Am J Kidney Dis"},{"issue":"11","key":"2910_CR9","doi-asserted-by":"publisher","first-page":"1816","DOI":"10.1093\/ndt\/gfz038","volume":"34","author":"A Hart","year":"2019","unstructured":"Hart A, Johansen KL (2019) Cardiovascular protection and mounting evidence for the benefits of intradialytic exercise. Nephrol Dial Transplant 34(11):1816\u20131818","journal-title":"Nephrol Dial Transplant"},{"issue":"1","key":"2910_CR10","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1046\/j.1523-1755.2003.00704.x","volume":"63","author":"KL Johansen","year":"2003","unstructured":"Johansen KL et al (2003) Muscle atrophy in patients receiving hemodialysis: effects on muscle strength, muscle quality, and physical function. Kidney Int 63(1):291\u2013297","journal-title":"Kidney Int"},{"issue":"2","key":"2910_CR11","doi-asserted-by":"publisher","first-page":"61","DOI":"10.4068\/cmj.2011.47.2.61","volume":"47","author":"TD Jung","year":"2011","unstructured":"Jung TD, Park SH (2011) Intradialytic exercise programs for hemodialysis patients. Chonnam Med J 47(2):61\u201365","journal-title":"Chonnam Med J"},{"issue":"16","key":"2910_CR12","doi-asserted-by":"publisher","first-page":"1782","DOI":"10.1001\/jama.2009.1488","volume":"302","author":"DJ de Jager","year":"2009","unstructured":"de Jager DJ et al (2009) Cardiovascular and noncardiovascular mortality among patients starting dialysis. JAMA 302(16):1782\u20131789","journal-title":"JAMA"},{"issue":"5","key":"2910_CR13","doi-asserted-by":"publisher","first-page":"680","DOI":"10.1016\/j.apmr.2005.12.044","volume":"87","author":"TL Parsons","year":"2006","unstructured":"Parsons TL, Toffelmire EB, King-VanVlack CE (2006) Exercise training during hemodialysis improves dialysis efficacy and physical performance. Arch Phys Med Rehabil 87(5):680\u2013687","journal-title":"Arch Phys Med Rehabil"},{"issue":"1","key":"2910_CR14","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1111\/j.1525-139X.2009.00652.x","volume":"23","author":"PN Bennett","year":"2010","unstructured":"Bennett PN et al (2010) Sustaining a hemodialysis exercise program: a review. Semin Dial 23(1):62\u201373","journal-title":"Semin Dial"},{"issue":"11","key":"2910_CR15","doi-asserted-by":"publisher","first-page":"1917","DOI":"10.1093\/ndt\/gfy376","volume":"34","author":"JD Penny","year":"2019","unstructured":"Penny JD et al (2019) Intradialytic exercise preconditioning: an exploratory study on the effect on myocardial stunning. Nephrol Dial Transplant 34(11):1917\u20131923","journal-title":"Nephrol Dial Transplant"},{"key":"2910_CR16","doi-asserted-by":"publisher","first-page":"1335","DOI":"10.1093\/ckj\/sfz159","volume":"14","author":"S McGuire","year":"2019","unstructured":"McGuire S et al (2019) Cardiac stunning during haemodialysis: the therapeutic effect of intra-dialytic exercise. Clin Kidney J 14:1335\u20131344","journal-title":"Clin Kidney J"},{"issue":"1","key":"2910_CR17","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1016\/j.jphys.2018.11.008","volume":"65","author":"KB Scapini","year":"2019","unstructured":"Scapini KB et al (2019) Combined training is the most effective training modality to improve aerobic capacity and blood pressure control in people requiring haemodialysis for end-stage renal disease: systematic review and network meta-analysis. J Physiother 65(1):4\u201315","journal-title":"J Physiother"},{"issue":"12","key":"2910_CR18","doi-asserted-by":"publisher","first-page":"1440","DOI":"10.1016\/j.echo.2005.10.005","volume":"18","author":"RM Lang","year":"2005","unstructured":"Lang RM et al (2005) Recommendations for chamber quantification: a report from the American Society of Echocardiography\u2019s Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology. J Am Soc Echocardiogr 18(12):1440\u20131463","journal-title":"J Am Soc Echocardiogr"},{"issue":"7","key":"2910_CR19","doi-asserted-by":"publisher","first-page":"956","DOI":"10.1093\/sleep\/33.7.956","volume":"33","author":"JE Gangwisch","year":"2010","unstructured":"Gangwisch JE et al (2010) Short sleep duration as a risk factor for hypercholesterolemia: analyses of the National Longitudinal Study of Adolescent Health. Sleep 33(7):956\u2013961","journal-title":"Sleep"},{"issue":"5","key":"2910_CR20","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1016\/0021-9681(87)90171-8","volume":"40","author":"ME Charlson","year":"1987","unstructured":"Charlson ME et al (1987) A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 40(5):373\u2013383","journal-title":"J Chronic Dis"},{"issue":"3","key":"2910_CR21","first-page":"207","volume":"8","author":"A Momeni","year":"2014","unstructured":"Momeni A, Nematolahi A, Nasr M (2014) Effect of intradialytic exercise on echocardiographic findings in hemodialysis patients. Iran J Kidney Dis 8(3):207\u2013211","journal-title":"Iran J Kidney Dis"},{"issue":"3","key":"2910_CR22","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1016\/S0167-5273(99)00090-X","volume":"70","author":"A Deligiannis","year":"1999","unstructured":"Deligiannis A et al (1999) Cardiac effects of exercise rehabilitation in hemodialysis patients. Int J Cardiol 70(3):253\u2013266","journal-title":"Int J Cardiol"},{"issue":"4","key":"2910_CR23","doi-asserted-by":"publisher","first-page":"261","DOI":"10.5414\/CNP61261","volume":"61","author":"TL Parsons","year":"2004","unstructured":"Parsons TL, Toffelmire EB, King-VanVlack CE (2004) The effect of an exercise program during hemodialysis on dialysis efficacy, blood pressure and quality of life in end-stage renal disease (ESRD) patients. Clin Nephrol 61(4):261\u2013274","journal-title":"Clin Nephrol"},{"issue":"6","key":"2910_CR24","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1053\/j.ackd.2009.08.009","volume":"16","author":"TL Parsons","year":"2009","unstructured":"Parsons TL, King-Vanvlack CE (2009) Exercise and end-stage kidney disease: functional exercise capacity and cardiovascular outcomes. Adv Chronic Kidney Dis 16(6):459\u2013481","journal-title":"Adv Chronic Kidney Dis"},{"issue":"1","key":"2910_CR25","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1186\/1471-2369-14-194","volume":"14","author":"CD Giannaki","year":"2013","unstructured":"Giannaki CD et al (2013) Effect of exercise training and dopamine agonists in patients with uremic restless legs syndrome: a six-month randomized, partially double-blind, placebo-controlled comparative study. BMC Nephrol 14(1):194","journal-title":"BMC Nephrol"},{"issue":"3","key":"2910_CR26","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1097\/MAT.0b013e318215dc9e","volume":"57","author":"CD Giannaki","year":"2011","unstructured":"Giannaki CD et al (2011) The effect of prolonged intradialytic exercise in hemodialysis efficiency indices. Asaio J 57(3):213\u2013218","journal-title":"Asaio J"},{"issue":"1","key":"2910_CR27","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1053\/j.ajkd.2009.09.025","volume":"55","author":"KP Koh","year":"2010","unstructured":"Koh KP et al (2010) Effect of intradialytic versus home-based aerobic exercise training on physical function and vascular parameters in hemodialysis patients: a randomized pilot study. Am J Kidney Dis 55(1):88\u201399","journal-title":"Am J Kidney Dis"},{"key":"2910_CR28","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1186\/1471-2369-10-2","volume":"10","author":"KP Koh","year":"2009","unstructured":"Koh KP et al (2009) Intradialytic versus home-based exercise training in hemodialysis patients: a randomised controlled trial. BMC Nephrol 10:2","journal-title":"BMC Nephrol"},{"key":"2910_CR29","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/j.smrv.2014.07.006","volume":"21","author":"GK Sakkas","year":"2015","unstructured":"Sakkas GK et al (2015) Current trends in the management of uremic restless legs syndrome: a systematic review on aspects related to quality of life, cardiovascular mortality and survival. Sleep Med Rev 21:39\u201349","journal-title":"Sleep Med Rev"}],"container-title":["International Urology and Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11255-021-02910-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11255-021-02910-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11255-021-02910-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,5]],"date-time":"2022-01-05T11:39:35Z","timestamp":1641382775000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11255-021-02910-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,7]]},"references-count":29,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["2910"],"URL":"https:\/\/doi.org\/10.1007\/s11255-021-02910-x","relation":{},"ISSN":["0301-1623","1573-2584"],"issn-type":[{"value":"0301-1623","type":"print"},{"value":"1573-2584","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,7]]},"assertion":[{"value":"11 December 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 May 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 June 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest\/Competing interests"}},{"value":"The study was approved by the Human Research and Ethics Committee of the University of Thessaly (634, 10\/10\/2012) and performed under ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"All patients gave their written informed consent prior to study participation.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Yes.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}]}}