{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T18:52:13Z","timestamp":1770490333800,"version":"3.49.0"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2022,1,26]],"date-time":"2022-01-26T00:00:00Z","timestamp":1643155200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,1,26]],"date-time":"2022-01-26T00:00:00Z","timestamp":1643155200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100014042","name":"DOD Peer Reviewed Cancer Research Program","doi-asserted-by":"publisher","award":["W81XWH-19-1-0288"],"award-info":[{"award-number":["W81XWH-19-1-0288"]}],"id":[{"id":"10.13039\/100014042","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Urol Nephrol"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The COVID-19 pandemic and subsequent lockdown had a substantial impact on normal research operations. Researchers needed to adapt their methods to engage at-home participants. One method is crowdsourcing, in which researchers use social media to recruit participants, gather data, and collect samples. We utilized this method to develop a diagnostic test for Interstitial Cystitis\/Bladder Pain Syndrome (IC\/BPS). Participants were recruited via posts on popular social-media platforms, and enrolled via a website. Participants received and returned a mail kit containing bladder symptom surveys and a urine sample cup containing room-temperature preservative. Using this method, we collected 1254 IC\/BPS and control samples in 3\u00a0months from all 50 United States. Our data demonstrate that crowdsourcing is a viable alternative to traditional research, with the ability to reach a broad patient population rapidly. Crowdsourcing is a powerful tool for at-home participation in research, particularly during the lockdown caused by the COVID-19 pandemic.<\/jats:p>","DOI":"10.1007\/s11255-022-03108-5","type":"journal-article","created":{"date-parts":[[2022,1,26]],"date-time":"2022-01-26T10:02:42Z","timestamp":1643191362000},"page":"493-498","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Using social media to crowdsource collection of urine samples during a national pandemic"],"prefix":"10.1007","volume":"54","author":[{"given":"Elijah P.","family":"Ward","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah N.","family":"Bartolone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prasun","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9480-8972","authenticated-orcid":false,"given":"Michael B.","family":"Chancellor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura E.","family":"Lamb","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,1,26]]},"reference":[{"key":"3108_CR1","first-page":"419","volume":"12","author":"M Akacha","year":"2020","unstructured":"Akacha M, Branson J, Bretz F, Dharan B, Gallo P, Gathamnn I, Hemings R, Jones J, Xi D, Zuber E (2020) Challenges in assessing the impact of the COVID-19 pandemic on the integrity and interpretability of clinical trials. SBR 12:419\u2013426","journal-title":"SBR"},{"key":"3108_CR2","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1186\/s13059-020-02031-1","volume":"21","author":"JO Korbel","year":"2020","unstructured":"Korbel JO, Stegle O (2020) Effects of the COVID-19 pandemic on life scientists. Genome Biol 21:113","journal-title":"Genome Biol"},{"key":"3108_CR3","unstructured":"Woolston C (2020). Nature, online article. vol 2021."},{"key":"3108_CR4","unstructured":"Bernard MA, Lauer M (2021). NIH Office of Extramural Research (NEXUS), online article. vol 2021."},{"key":"3108_CR5","doi-asserted-by":"crossref","unstructured":"Tucker JD, Day S, Tang W, Bayus B (2019). Crowdsourcing in medical research: concepts and applications. PeerJ 7, e6762.","DOI":"10.7717\/peerj.6762"},{"key":"3108_CR6","doi-asserted-by":"crossref","unstructured":"Swan M (2012). Crowdsourced health research studies: an important emerging complement to clinical trials in the public health research ecosystem. 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Genomic characterization and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. The Lancet."},{"key":"3108_CR13","doi-asserted-by":"crossref","unstructured":"Lamb LE, Janicki JJ, Bartolone SN, Peters KM, Chancellor MB (2017). Development of an interstitial cystitis risk score for bladder permeability. PloS one 12, e0185686.","DOI":"10.1371\/journal.pone.0185686"},{"issue":"1","key":"3108_CR14","doi-asserted-by":"publisher","first-page":"2","DOI":"10.4103\/UROS.UROS_155_20","volume":"32","author":"MB Chancellor","year":"2021","unstructured":"Chancellor MB, Lamb LE (2021) Toward a validated diagnostic test with machine learning algorithm for interstitial cystitis. Urol Sci 32(1):2\u20137","journal-title":"Urol Sci"}],"container-title":["International Urology and Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11255-022-03108-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11255-022-03108-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11255-022-03108-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,10]],"date-time":"2022-02-10T13:28:49Z","timestamp":1644499729000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11255-022-03108-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,26]]},"references-count":14,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,3]]}},"alternative-id":["3108"],"URL":"https:\/\/doi.org\/10.1007\/s11255-022-03108-5","relation":{},"ISSN":["0301-1623","1573-2584"],"issn-type":[{"value":"0301-1623","type":"print"},{"value":"1573-2584","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1,26]]},"assertion":[{"value":"13 December 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 January 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 January 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"LEL and MBC have intellectual property associated with methods for diagnosing interstitial cystitis. All other authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interests"}}]}}