{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T07:53:04Z","timestamp":1775807584297,"version":"3.50.1"},"reference-count":52,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2023,8,11]],"date-time":"2023-08-11T00:00:00Z","timestamp":1691712000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,8,11]],"date-time":"2023-08-11T00:00:00Z","timestamp":1691712000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Urol Nephrol"],"DOI":"10.1007\/s11255-023-03735-6","type":"journal-article","created":{"date-parts":[[2023,8,11]],"date-time":"2023-08-11T07:02:25Z","timestamp":1691737345000},"page":"3077-3087","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Protective potential of pterostilbene against cyclophosphamide-induced nephrotoxicity and cystitis in rats"],"prefix":"10.1007","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4349-7796","authenticated-orcid":false,"given":"G\u00f6k\u00e7en","family":"Kerimo\u011flu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tu\u011fba","family":"Ar\u0131c\u0131","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ay\u015fe Firuze","family":"B\u0131y\u0131k","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Kulaber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nihal","family":"T\u00fcrkmen Alemdar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Selim","family":"Demir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y\u00fcksel","family":"Aliyaz\u0131c\u0131o\u011flu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Engin","family":"Yenilmez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,8,11]]},"reference":[{"key":"3735_CR1","unstructured":"Ogino MH, Tadi P (2022) Cyclophosphamide. In: StatPearls. StatPearls Publishing. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK553087\/. Accessed 19 May 2023"},{"key":"3735_CR2","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1155\/2022\/5096825","volume":"51","author":"MA Ayza","year":"2022","unstructured":"Ayza MA, Zewdie KA, Yigzaw EF et al (2022) Potential protective effects of antioxidants against cyclophosphamide-induced nephrotoxicity. Int J Nephrol 51:803\u2013810. https:\/\/doi.org\/10.1155\/2022\/5096825","journal-title":"Int J Nephrol"},{"issue":"8","key":"3735_CR3","doi-asserted-by":"publisher","first-page":"1145","DOI":"10.1016\/j.dnarep.2007.03.010","volume":"6","author":"RJ Hansen","year":"2007","unstructured":"Hansen RJ, Ludeman SM, Paikoff SJ et al (2007) Role of MGMT in protecting against cyclophosphamide-induced toxicity in cells and animals. DNA Repair 6(8):1145\u20131154. https:\/\/doi.org\/10.1016\/j.dnarep.2007.03.010","journal-title":"DNA Repair"},{"issue":"3","key":"3735_CR4","doi-asserted-by":"publisher","first-page":"911","DOI":"10.3390\/jcm12030911","volume":"12","author":"MF Alam","year":"2023","unstructured":"Alam MF, Ajeibi AO, Safhi MH et al (2023) Therapeutic potential of capsaicin against cyclophosphamide-induced liver damage. J Clin Med 12(3):911. https:\/\/doi.org\/10.3390\/jcm12030911","journal-title":"J Clin Med"},{"key":"3735_CR5","doi-asserted-by":"publisher","DOI":"10.1007\/s11010-023-04662-x.Advanceonlinepublication.10.1007\/s11010-023-04662-x","author":"EHM Hassanein","year":"2023","unstructured":"Hassanein EHM, Kamel EO, Gad-Elrab WM et al (2023) Lansoprazole attenuates cyclophosphamide-induced cardiopulmonary injury by modulating redox-sensitive pathways and inflammation. Mol Cell Biochem. https:\/\/doi.org\/10.1007\/s11010-023-04662-x.Advanceonlinepublication.10.1007\/s11010-023-04662-x","journal-title":"Mol Cell Biochem"},{"issue":"19","key":"3735_CR6","doi-asserted-by":"publisher","first-page":"11615","DOI":"10.3390\/ijms231911615","volume":"23","author":"S Alshahrani","year":"2022","unstructured":"Alshahrani S, Ali Thubab HM, Ali Zaeri AM et al (2022) The protective effects of Sesamin against cyclophosphamide-induced nephrotoxicity through modulation of oxidative stress, inflammatory-cytokines and apoptosis in rats. Int J Mol Sci 23(19):11615. https:\/\/doi.org\/10.3390\/ijms231911615","journal-title":"Int J Mol Sci"},{"issue":"1","key":"3735_CR7","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1007\/s12011-019-01969-z","volume":"197","author":"A Ayhanci","year":"2020","unstructured":"Ayhanci A, Tanriverdi DT, Sahinturk V et al (2020) Protective effects of boron on cyclophosphamide-induced bladder damage and oxidative stress in rats. Biol Trace Elem Res 197(1):184\u2013191. https:\/\/doi.org\/10.1007\/s12011-019-01969-z","journal-title":"Biol Trace Elem Res"},{"key":"3735_CR8","doi-asserted-by":"publisher","first-page":"173310","DOI":"10.1016\/j.ejphar.2020.173310","volume":"883","author":"MR Zirak","year":"2020","unstructured":"Zirak MR, Karimi G, Rahimian R et al (2020) Tropisetron ameliorates cyclophosphamide-induced hemorrhagic cystitis in rats. Eur J Pharmacol 883:173310. https:\/\/doi.org\/10.1016\/j.ejphar.2020.173310","journal-title":"Eur J Pharmacol"},{"issue":"2","key":"3735_CR9","doi-asserted-by":"crossref","first-page":"89","DOI":"10.59566\/IJBS.2008.4089","volume":"4","author":"LA Pham-Huy","year":"2008","unstructured":"Pham-Huy LA, He H, Pham-Huy C (2008) Free radicals, antioxidants in disease and health. Int J Biomed Sci 4(2):89\u201396","journal-title":"Int J Biomed Sci"},{"issue":"1","key":"3735_CR10","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1007\/s12291-014-0446-0","volume":"30","author":"A Phaniendra","year":"2015","unstructured":"Phaniendra A, Jestadi DB, Periyasamy L (2015) Free radicals: properties, sources, targets, and their implication in various diseases. Indian J Clin Biochem 30(1):11\u201326. https:\/\/doi.org\/10.1007\/s12291-014-0446-0","journal-title":"Indian J Clin Biochem"},{"issue":"3","key":"3735_CR11","doi-asserted-by":"publisher","first-page":"552","DOI":"10.3390\/cells11030552","volume":"11","author":"YA Hajam","year":"2022","unstructured":"Hajam YA, Rani R, Ganie SY et al (2022) Oxidative stress in human pathology and aging: molecular mechanisms and perspectives. Cells 11(3):552. https:\/\/doi.org\/10.3390\/cells11030552","journal-title":"Cells"},{"issue":"19","key":"3735_CR12","doi-asserted-by":"publisher","first-page":"6316","DOI":"10.3390\/molecules27196316","volume":"27","author":"S Nagarajan","year":"2022","unstructured":"Nagarajan S, Mohandas S, Ganesan K et al (2022) New insights into dietary Pterostilbene: sources, metabolism, and health promotion effects. Molecules (Basel, Switzerland) 27(19):6316. https:\/\/doi.org\/10.3390\/molecules27196316","journal-title":"Molecules (Basel, Switzerland)"},{"issue":"3","key":"3735_CR13","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1007\/s00280-010-1525-4","volume":"68","author":"IM Kapetanovic","year":"2011","unstructured":"Kapetanovic IM, Muzzio M, Huang Z et al (2011) Pharmacokinetics, oral bioavailability, and metabolic profile of resveratrol and its dimethylether analog, pterostilbene, in rats. Cancer Chemother Pharmacol 68(3):593\u2013601. https:\/\/doi.org\/10.1007\/s00280-010-1525-4","journal-title":"Cancer Chemother Pharmacol"},{"key":"3735_CR14","doi-asserted-by":"publisher","first-page":"575482","DOI":"10.1155\/2013\/575482","volume":"2013","author":"D McCormack","year":"2013","unstructured":"McCormack D, McFadden D (2013) A review of pterostilbene antioxidant activity and disease modification. Oxid Med Cell Longev 2013:575482. https:\/\/doi.org\/10.1155\/2013\/575482","journal-title":"Oxid Med Cell Longev"},{"issue":"3","key":"3735_CR15","doi-asserted-by":"publisher","first-page":"65","DOI":"10.3109\/10408363.2013.805182","volume":"50","author":"JM Estrela","year":"2013","unstructured":"Estrela JM, Ortega A, Mena S et al (2013) Pterostilbene: biomedical applications. Crit Rev Clin Lab Sci 50(3):65\u201378. https:\/\/doi.org\/10.3109\/10408363.2013.805182","journal-title":"Crit Rev Clin Lab Sci"},{"issue":"1","key":"3735_CR16","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1002\/biof.1400","volume":"44","author":"YR Li","year":"2018","unstructured":"Li YR, Li S, Lin CC (2018) Effect of resveratrol and Pterostilbene on aging and longevity. BioFactors 44(1):69\u201382. https:\/\/doi.org\/10.1002\/biof.1400","journal-title":"BioFactors"},{"issue":"4","key":"3735_CR17","doi-asserted-by":"publisher","first-page":"3551","DOI":"10.3892\/etm.2018.5808","volume":"15","author":"Y Xia","year":"2018","unstructured":"Xia Y, Chen Y, Tang L et al (2018) Pterostilbene attenuates acute kidney injury in septic mice. Exp Ther Med 15(4):3551\u20133555. https:\/\/doi.org\/10.3892\/etm.2018.5808","journal-title":"Exp Ther Med"},{"issue":"1\u20132","key":"3735_CR18","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1159\/000500293","volume":"104","author":"Y Zhang","year":"2019","unstructured":"Zhang Y, Ren S, Ji Y, Liang Y (2019) Pterostilbene ameliorates nephropathy injury in Streptozotocin-induced diabetic rats. Pharmacology 104(1\u20132):71\u201380. https:\/\/doi.org\/10.1159\/000500293","journal-title":"Pharmacology"},{"key":"3735_CR19","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1016\/j.cbi.2014.11.001","volume":"224","author":"AM Abd El Tawab","year":"2014","unstructured":"Abd El Tawab AM, Shahin NN, AbdelMohsen MM (2014) Protective effect of Satureja montana extract on cyclophosphamide-induced testicular injury in rats. Chem Biol Interact 224:196\u2013205. https:\/\/doi.org\/10.1016\/j.cbi.2014.11.001","journal-title":"Chem Biol Interact"},{"issue":"1","key":"3735_CR20","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1080\/13880209.2022.2034893","volume":"60","author":"Y Li","year":"2022","unstructured":"Li Y, Wang SM, Li X et al (2022) Pterostilbene pre-treatment reduces LPS-induced acute lung injury through activating NR4A1. Pharm Biol 60(1):394\u2013403. https:\/\/doi.org\/10.1080\/13880209.2022.2034893","journal-title":"Pharm Biol"},{"issue":"4","key":"3735_CR21","doi-asserted-by":"publisher","first-page":"629","DOI":"10.3109\/0886022X.2016.1149868","volume":"38","author":"EB Sancak","year":"2016","unstructured":"Sancak EB, Akbas A, Silan C et al (2016) Protective effect of syringic acid on kidney ischemia reperfusion injury. Ren Fail 38(4):629\u2013635. https:\/\/doi.org\/10.3109\/0886022X.2016.1149868","journal-title":"Ren Fail"},{"issue":"11","key":"3735_CR22","doi-asserted-by":"publisher","first-page":"4273","DOI":"10.1007\/s00520-019-04731-2","volume":"27","author":"S Engin","year":"2019","unstructured":"Engin S, Barut EN, Barut B et al (2019) Uroprotective effect of pantoprazole against cyclophosphamide-induced cystitis in mice. Support Care Cancer 27(11):4273\u20134281. https:\/\/doi.org\/10.1007\/s00520-019-04731-2","journal-title":"Support Care Cancer"},{"key":"3735_CR23","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jchemneu.2018.01.001","volume":"91","author":"G Kerimoglu","year":"2018","unstructured":"Kerimoglu G, Guney C, Ersoz S, Odaci E (2018) A histopathological and biochemical evaluation of oxidative injury in the sciatic nerves of male rats exposed to a continuous 900-megahertz electromagnetic field throughout all periods of adolescence. J Chem Neuroanat 91:1\u20137. https:\/\/doi.org\/10.1016\/j.jchemneu.2018.01.001","journal-title":"J Chem Neuroanat"},{"issue":"1","key":"3735_CR24","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1016\/0003-2697(78)90342-1","volume":"86","author":"M Mihara","year":"1978","unstructured":"Mihara M, Uchiyama M (1978) Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. Anal Biochem 86(1):271\u2013278. https:\/\/doi.org\/10.1016\/0003-2697(78)90342-1","journal-title":"Anal Biochem"},{"issue":"8","key":"3735_CR25","doi-asserted-by":"publisher","first-page":"3584","DOI":"10.1080\/01443615.2022.2130201","volume":"42","author":"A Mentese","year":"2022","unstructured":"Mentese A, Alemdar NT, Livaoglu A et al (2022) Suppression of cisplatin-induced ovarian injury in rats by chrysin: an experimental study. J Obstet Gynaecol 42(8):3584\u20133590. https:\/\/doi.org\/10.1080\/01443615.2022.2130201","journal-title":"J Obstet Gynaecol"},{"key":"3735_CR26","unstructured":"World Health Organization (WHO) (2022) Cancer. WHO Web. https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/cancer. Accessed 19 May 2023"},{"issue":"11","key":"3735_CR27","doi-asserted-by":"publisher","first-page":"638","DOI":"10.1038\/nrclinonc.2009.146","volume":"6","author":"A Emadi","year":"2009","unstructured":"Emadi A, Jones RJ, Brodsky RA (2009) Cyclophosphamide and cancer: golden anniversary. Nat Rev Clin Oncol 6(11):638\u2013647. https:\/\/doi.org\/10.1038\/nrclinonc.2009.146","journal-title":"Nat Rev Clin Oncol"},{"issue":"4","key":"3735_CR28","doi-asserted-by":"publisher","first-page":"190","DOI":"10.5306\/wjco.v11.i4.190","volume":"11","author":"MLC Santos","year":"2020","unstructured":"Santos MLC, de Brito BB, da Silva FAF et al (2020) Nephrotoxicity in cancer treatment: an overview. World J Clin Oncol 11(4):190\u2013204. https:\/\/doi.org\/10.5306\/wjco.v11.i4.190","journal-title":"World J Clin Oncol"},{"key":"3735_CR29","doi-asserted-by":"publisher","first-page":"960327122113214","DOI":"10.1177\/09603271221132140","volume":"41","author":"MU Ijaz","year":"2022","unstructured":"Ijaz MU, Mustafa S, Batool R et al (2022) Ameliorative effect of herbacetin against cyclophosphamide-induced nephrotoxicity in rats via attenuation of oxidative stress, inflammation, apoptosis and mitochondrial dysfunction. Hum Exp Toxicol 41:9603271221132140. https:\/\/doi.org\/10.1177\/09603271221132140","journal-title":"Hum Exp Toxicol"},{"issue":"12","key":"3735_CR30","doi-asserted-by":"publisher","first-page":"2301","DOI":"10.1007\/s11255-014-0833-8","volume":"46","author":"I Keles","year":"2014","unstructured":"Keles I, Bozkurt MF, Cemek M et al (2014) Prevention of cyclophosphamide-induced hemorrhagic cystitis by resveratrol: a comparative experimental study with mesna. Int Urol Nephrol 46(12):2301\u20132310. https:\/\/doi.org\/10.1007\/s11255-014-0833-8","journal-title":"Int Urol Nephrol"},{"issue":"1","key":"3735_CR31","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1007\/s11255-022-03246-w","volume":"55","author":"RS Abdelrahman","year":"2023","unstructured":"Abdelrahman RS, Nashar EME, Alghamdi MA et al (2023) Phosphodiesterase1 inhibitor \u201cVinpocetine\u201d ameliorates the inflammation, apoptosis and oxidative stress induced by cyclophosphamide in urinary bladder: an experimental study. Int Urol Nephrol 55(1):129\u2013139. https:\/\/doi.org\/10.1007\/s11255-022-03246-w","journal-title":"Int Urol Nephrol"},{"issue":"3","key":"3735_CR32","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1007\/s00210-019-01741-z","volume":"393","author":"Y Temel","year":"2020","unstructured":"Temel Y, Kucukler S, Y\u0131ld\u0131r\u0131m S et al (2020) Protective effect of chrysin on cyclophosphamide-induced hepatotoxicity and nephrotoxicity via the inhibition of oxidative stress, inflammation, and apoptosis. Naunyn Schmiedebergs Arch Pharmacol 393(3):325\u2013337. https:\/\/doi.org\/10.1007\/s00210-019-01741-z","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"key":"3735_CR33","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1186\/1472-6882-13-238","volume":"13","author":"JD Acharya","year":"2013","unstructured":"Acharya JD, Ghaskadbi SS (2013) Protective effect of Pterostilbene against free radical mediated oxidative damage. BMC Complement Altern Med 13:238. https:\/\/doi.org\/10.1186\/1472-6882-13-238","journal-title":"BMC Complement Altern Med"},{"key":"3735_CR34","doi-asserted-by":"publisher","first-page":"352091","DOI":"10.1155\/2012\/352091","volume":"2012","author":"E Taghiabadi","year":"2012","unstructured":"Taghiabadi E, Imenshahidi M, Abnous K et al (2012) Protective effect of silymarin against acrolein-\u0131nduced cardiotoxicity in mice. Evid Based Complement Alternat Med 2012:352091. https:\/\/doi.org\/10.1155\/2012\/352091","journal-title":"Evid Based Complement Alternat Med"},{"issue":"5","key":"3735_CR35","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1007\/s11255-019-02128-y","volume":"51","author":"EN Barut","year":"2019","unstructured":"Barut EN, Engin S, Barut B et al (2019) Uroprotective effect of ambroxol in cyclophosphamide-induced cystitis in mice. Int Urol Nephrol 51(5):803\u2013810. https:\/\/doi.org\/10.1007\/s11255-019-02128-y","journal-title":"Int Urol Nephrol"},{"issue":"4","key":"3735_CR36","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1538\/expanim.22-0030","volume":"71","author":"N Akbas","year":"2022","unstructured":"Akbas N, Suleyman B, Mammadov R et al (2022) Effect of taxifolin on cyclophosphamide-induced oxidative and inflammatory bladder injury in rats. Exp Anim 71(4):460\u2013467. https:\/\/doi.org\/10.1538\/expanim.22-0030","journal-title":"Exp Anim"},{"key":"3735_CR37","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.ejmech.2015.04.040","volume":"97","author":"AM Pisoschi","year":"2015","unstructured":"Pisoschi AM, Pop A (2015) The role of antioxidants in the chemistry of oxidative stress: a review. Eur J Med Chem 97:55\u201374. https:\/\/doi.org\/10.1016\/j.ejmech.2015.04.040","journal-title":"Eur J Med Chem"},{"issue":"12","key":"3735_CR38","doi-asserted-by":"publisher","first-page":"1237","DOI":"10.3390\/ph14121237","volume":"14","author":"A Merwid-Lad","year":"2021","unstructured":"Merwid-Lad A, Ziolkowski P, Szandruk-Bender M et al (2021) Effect of a low dose of carvedilol on cyclophosphamide-induced urinary toxicity in rats-A comparison with Mesna. Pharm Basel 14(12):1237. https:\/\/doi.org\/10.3390\/ph14121237","journal-title":"Pharm Basel"},{"issue":"1","key":"3735_CR39","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1007\/s12011-017-1231-8","volume":"185","author":"S Gunes","year":"2018","unstructured":"Gunes S, Sahinturk V, Uslu S et al (2018) Protective effects of selenium on cyclophosphamide-induced oxidative stress and kidney injury. Biol Trace Elem Res 185(1):116\u2013123. https:\/\/doi.org\/10.1007\/s12011-017-1231-8","journal-title":"Biol Trace Elem Res"},{"issue":"1","key":"3735_CR40","doi-asserted-by":"publisher","first-page":"1029","DOI":"10.3892\/etm.2017.5479","volume":"15","author":"D Gao","year":"2018","unstructured":"Gao D, Jing S, Zhang Q, Wu G (2018) Pterostilbene protects against acute renal ischemia reperfusion injury and inhibits oxidative stress, inducible nitric oxide synthase expression and inflammation in rats via the Toll-like receptor 4\/nuclear factor-\u03baB signaling pathway. Exp Ther Med 15(1):1029\u20131035. https:\/\/doi.org\/10.3892\/etm.2017.5479","journal-title":"Exp Ther Med"},{"issue":"2","key":"3735_CR41","doi-asserted-by":"publisher","first-page":"435","DOI":"10.36660\/abc.20201155","volume":"118","author":"S Tasca","year":"2022","unstructured":"Tasca S, Campos C, Lacerda D et al (2022) Pterostilbene reduces experimental myocardial infarction-induced oxidative stress in lung and right ventricle. Arq Bras Cardiol 118(2):435\u2013445. https:\/\/doi.org\/10.36660\/abc.20201155","journal-title":"Arq Bras Cardiol"},{"issue":"6","key":"3735_CR42","doi-asserted-by":"publisher","first-page":"1392.e1","DOI":"10.1016\/j.urology.2012.06.053","volume":"80","author":"O Sinanoglu","year":"2012","unstructured":"Sinanoglu O, Yener AN, Ekici S et al (2012) The protective effects of spirulina in cyclophosphamide induced nephrotoxicity and urotoxicity in rats. Urology 80(6):1392.e1\u20136. https:\/\/doi.org\/10.1016\/j.urology.2012.06.053","journal-title":"Urology"},{"issue":"6","key":"3735_CR43","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1097\/CAD.0000000000000912","volume":"31","author":"G Voelcker","year":"2020","unstructured":"Voelcker G (2020) Causes and possibilities to circumvent cyclophosphamide toxicity. Anticancer Drugs 31(6):617\u2013622. https:\/\/doi.org\/10.1097\/CAD.0000000000000912","journal-title":"Anticancer Drugs"},{"issue":"4","key":"3735_CR44","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1080\/01926230701320337","volume":"35","author":"S Elmore","year":"2007","unstructured":"Elmore S (2007) Apoptosis: a review of programmed cell death. Toxicol Pathol 35(4):495\u2013516. https:\/\/doi.org\/10.1080\/01926230701320337","journal-title":"Toxicol Pathol"},{"key":"3735_CR45","doi-asserted-by":"publisher","first-page":"1147823","DOI":"10.3389\/fphar.2023.1147823","volume":"14","author":"V Yadav","year":"2023","unstructured":"Yadav V, Krishnan A, Zahiruddin S et al (2023) Amelioration of cyclophosphamide-induced DNA damage, oxidative stress, and hepato- and neurotoxicity by Piper longum extract in rats: The role of \u03b3H2AX and 8-OHdG. Front Pharmacol 14:1147823. https:\/\/doi.org\/10.3389\/fphar.2023.1147823","journal-title":"Front Pharmacol"},{"issue":"2","key":"3735_CR46","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1530\/JOE-18-0370","volume":"240","author":"Y Luan","year":"2019","unstructured":"Luan Y, Edmonds ME, Woodruff TK, Kim SY (2019) Inhibitors of apoptosis protect the ovarian reserve from cyclophosphamide. J Endocrinol 240(2):243\u2013256. https:\/\/doi.org\/10.1530\/JOE-18-0370","journal-title":"J Endocrinol"},{"issue":"5","key":"3735_CR47","doi-asserted-by":"publisher","first-page":"526","DOI":"10.22038\/IJBMS.2023.68579.14960","volume":"26","author":"S Rezaei","year":"2023","unstructured":"Rezaei S, Hosseinimehr SJ, Zargari M et al (2023) Sinapic acid attenuates cyclophosphamide-induced liver toxicity in mice by modulating oxidative stress, NF-\u03baB, and caspase-3. Iran J Basic Med Sci 26(5):526\u2013531. https:\/\/doi.org\/10.22038\/IJBMS.2023.68579.14960","journal-title":"Iran J Basic Med Sci"},{"issue":"3","key":"3735_CR48","doi-asserted-by":"publisher","first-page":"2090","DOI":"10.3892\/etm.2020.8923","volume":"20","author":"X Xiong","year":"2020","unstructured":"Xiong X, Lu W, Zhang K, Zhou W (2020) Pterostilbene reduces endothelial cell apoptosis by regulation of the Nrf2-mediated TLR-4\/MyD88\/NF-\u03baB pathway in a rat model of atherosclerosis. Exp Ther Med 20(3):2090\u20132098. https:\/\/doi.org\/10.3892\/etm.2020.8923","journal-title":"Exp Ther Med"},{"issue":"1","key":"3735_CR49","doi-asserted-by":"publisher","first-page":"45","DOI":"10.3892\/etm.2019.8211","volume":"19","author":"T Tang","year":"2020","unstructured":"Tang T, Duan Z, Xu J et al (2020) Pterostilbene reduces endothelial cell injury in vascular arterial walls by regulating the Nrf2-mediated AMPK\/STAT3 pathway in an atherosclerosis rat model. Exp Ther Med 19(1):45\u201352. https:\/\/doi.org\/10.3892\/etm.2019.8211","journal-title":"Exp Ther Med"},{"issue":"3","key":"3735_CR50","doi-asserted-by":"publisher","first-page":"1531","DOI":"10.3906\/sag-2003-10","volume":"51","author":"FY Ozatik","year":"2021","unstructured":"Ozatik FY, Ozatik O, Teksen Y et al (2021) Protective and therapeutic effect of hydrogen sulfide on hemorrhagic cystitis and testis dysfunction induced with cyclophosphamide. Turk J Med Sci 51(3):1531\u20131543. https:\/\/doi.org\/10.3906\/sag-2003-10","journal-title":"Turk J Med Sci"},{"key":"3735_CR51","doi-asserted-by":"publisher","first-page":"120590","DOI":"10.1016\/j.lfs.2022.120590","volume":"301","author":"S Engin","year":"2022","unstructured":"Engin S, Barut EN, Ya\u015far YK et al (2022) Trimetazidine attenuates cyclophosphamide-induced cystitis by inhibiting TLR4-mediated NF\u03baB signaling in mice. Life Sci 301:120590. https:\/\/doi.org\/10.1016\/j.lfs.2022.120590","journal-title":"Life Sci"},{"issue":"4","key":"3735_CR52","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1080\/08923973.2017.1318913","volume":"39","author":"AA El-Sheikh","year":"2017","unstructured":"El-Sheikh AA, Morsy MA, Okasha AM (2017) Inhibition of NF-\u03baB\/TNF-\u03b1 pathway may be involved in the protective effect of resveratrol against cyclophosphamide-induced multi-organ toxicity. Immunopharmacol Immunotoxicol 39(4):180\u2013187. https:\/\/doi.org\/10.1080\/08923973.2017.1318913","journal-title":"Immunopharmacol Immunotoxicol"}],"container-title":["International Urology and Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11255-023-03735-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11255-023-03735-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11255-023-03735-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,18]],"date-time":"2023-12-18T22:06:12Z","timestamp":1702937172000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11255-023-03735-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,11]]},"references-count":52,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2023,12]]}},"alternative-id":["3735"],"URL":"https:\/\/doi.org\/10.1007\/s11255-023-03735-6","relation":{},"ISSN":["1573-2584"],"issn-type":[{"value":"1573-2584","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,11]]},"assertion":[{"value":"7 June 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 August 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 August 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no competing interests to declare that are relevant to the content of this article.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}