{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T07:50:50Z","timestamp":1740124250760,"version":"3.37.3"},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T00:00:00Z","timestamp":1692662400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T00:00:00Z","timestamp":1692662400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Urol Nephrol"],"DOI":"10.1007\/s11255-023-03741-8","type":"journal-article","created":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T09:02:19Z","timestamp":1692694939000},"page":"597-606","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Cardiorenal syndrome and iron supplementation\u2014more benefits than risks: a narrative review"],"prefix":"10.1007","volume":"56","author":[{"given":"Georgia","family":"Doumani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georgios","family":"Spanos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Panagiotis","family":"Theofilis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aikaterini","family":"Vordoni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7773-7575","authenticated-orcid":false,"given":"Rigas G.","family":"Kalaitzidis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,8,22]]},"reference":[{"issue":"6","key":"3741_CR1","doi-asserted-by":"publisher","first-page":"703","DOI":"10.1093\/eurheartj\/ehp507","volume":"31","author":"C Ronco","year":"2010","unstructured":"Ronco C, McCullough P, Anker SD, Anand I, Aspromonte N, Bagshaw SM, Bellomo R, Berl T, Bobek I, Cruz DN, Daliento L, Davenport A, Haapio M, Hillege H, House AA, Katz N, Maisel A, Mankad S, Zanco P, Mebazaa A, Palazzuoli A, Ronco F, Shaw A, Sheinfeld G, Soni S, Vescovo G, Zamperetti N, Ponikowski P, Acute Dialysis Quality Initiative (ADQI) consensus group (2010) Cardio-renal syndromes: report from the consensus conference of the acute dialysis quality initiative. Eur Heart J 31(6):703\u2013711. https:\/\/doi.org\/10.1093\/eurheartj\/ehp507","journal-title":"Eur Heart J"},{"issue":"26","key":"3741_CR2","doi-asserted-by":"publisher","first-page":"1986","DOI":"10.1056\/NEJM199912233412607","volume":"341","author":"NC Andrews","year":"1999","unstructured":"Andrews NC (1999) Disorders of iron metabolism. N Engl J Med 341(26):1986\u20131995. https:\/\/doi.org\/10.1056\/NEJM199912233412607","journal-title":"N Engl J Med"},{"issue":"2","key":"3741_CR3","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1111\/eci.12032","volume":"43","author":"C Datz","year":"2013","unstructured":"Datz C, Felder TK, Niederseer D, Aigner E (2013) Iron homeostasis in the metabolic syndrome. Eur J Clin Invest 43(2):215\u2013224. https:\/\/doi.org\/10.1111\/eci.12032","journal-title":"Eur J Clin Invest"},{"issue":"12","key":"3741_CR4","doi-asserted-by":"publisher","first-page":"4147","DOI":"10.2337\/dc13-0528","volume":"36","author":"B Ponikowska","year":"2013","unstructured":"Ponikowska B, Suchocki T, Paleczny B, Olesinska M, Powierza S, Borodulin-Nadzieja L, Reczuch K, von Haehling S, Doehner W, Anker SD, Cleland JG, Jankowska EA (2013) Iron status and survival in diabetic patients with coronary artery disease. Diabetes Care 36(12):4147\u20134156. https:\/\/doi.org\/10.2337\/dc13-0528","journal-title":"Diabetes Care"},{"issue":"11","key":"3741_CR5","doi-asserted-by":"publisher","first-page":"1339","DOI":"10.1093\/rheumatology\/kep221","volume":"48","author":"JF Baker","year":"2009","unstructured":"Baker JF, Ghio AJ (2009) Iron homoeostasis in rheumatic disease. Rheumatology (Oxford) 48(11):1339\u20131344. https:\/\/doi.org\/10.1093\/rheumatology\/kep221","journal-title":"Rheumatology (Oxford)"},{"issue":"8","key":"3741_CR6","doi-asserted-by":"publisher","first-page":"882","DOI":"10.1093\/eurjhf\/hfs056","volume":"14","author":"IC Macdougall","year":"2012","unstructured":"Macdougall IC, Canaud B, de Francisco AL, Filippatos G, Ponikowski P, Silverberg D, van Veldhuisen DJ, Anker SD (2012) Beyond the cardiorenal anaemia syndrome: recognizing the role of iron deficiency. Eur J Heart Fail 14(8):882\u2013886. https:\/\/doi.org\/10.1093\/eurjhf\/hfs056","journal-title":"Eur J Heart Fail"},{"issue":"19","key":"3741_CR7","doi-asserted-by":"publisher","first-page":"1747","DOI":"10.1016\/j.jacc.2009.05.015","volume":"54","author":"F Triposkiadis","year":"2009","unstructured":"Triposkiadis F, Karayannis G, Giamouzis G, Skoularigis J, Louridas G, Butler J (2009) The sympathetic nervous system in heart failure physiology, pathophysiology, and clinical implications. J Am Coll Cardiol 54(19):1747\u20131762. https:\/\/doi.org\/10.1016\/j.jacc.2009.05.015","journal-title":"J Am Coll Cardiol"},{"issue":"2","key":"3741_CR8","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1016\/j.semnephrol.2016.02.001","volume":"36","author":"T Ganz","year":"2016","unstructured":"Ganz T, Nemeth E (2016) Iron balance and the role of hepcidin in chronic kidney disease. Semin Nephrol 36(2):87\u201393. https:\/\/doi.org\/10.1016\/j.semnephrol.2016.02.001","journal-title":"Semin Nephrol"},{"issue":"3","key":"3741_CR9","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1681\/ASN.2019020213","volume":"31","author":"EK Batchelor","year":"2020","unstructured":"Batchelor EK, Kapitsinou P, Pergola PE, Kovesdy CP, Jalal DI (2020) Iron deficiency in chronic kidney disease: updates on pathophysiology, diagnosis, and treatment. J Am Soc Nephrol 31(3):456\u2013468. https:\/\/doi.org\/10.1681\/ASN.2019020213","journal-title":"J Am Soc Nephrol"},{"issue":"21","key":"3741_CR10","doi-asserted-by":"publisher","first-page":"2232","DOI":"10.1093\/eurheartj\/ehi388","volume":"26","author":"C Opasich","year":"2005","unstructured":"Opasich C, Cazzola M, Scelsi L, De Feo S, Bosimini E, Lagioia R, Febo O, Ferrari R, Fucili A, Moratti R, Tramarin R, Tavazzi L (2005) Blunted erythropoietin production and defective iron supply for erythropoiesis as major causes of anaemia in patients with chronic heart failure. Eur Heart J 26(21):2232\u20132237. https:\/\/doi.org\/10.1093\/eurheartj\/ehi388","journal-title":"Eur Heart J"},{"key":"3741_CR11","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.ejim.2018.04.013","volume":"52","author":"GJL Cunha","year":"2018","unstructured":"Cunha GJL, Rocha BML, Menezes Falcao L (2018) Iron deficiency in chronic and acute heart failure: a contemporary review on intertwined conditions. Eur J Intern Med 52:1\u20137. https:\/\/doi.org\/10.1016\/j.ejim.2018.04.013","journal-title":"Eur J Intern Med"},{"issue":"2","key":"3741_CR12","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1161\/01.cir.0000052622.51963.fc","volume":"107","author":"JA Ezekowitz","year":"2003","unstructured":"Ezekowitz JA, McAlister FA, Armstrong PW (2003) Anemia is common in heart failure and is associated with poor outcomes: insights from a cohort of 12065 patients with new-onset heart failure. Circulation 107(2):223\u2013225. https:\/\/doi.org\/10.1161\/01.cir.0000052622.51963.fc","journal-title":"Circulation"},{"issue":"6","key":"3741_CR13","doi-asserted-by":"publisher","first-page":"655","DOI":"10.1002\/ejhf.84","volume":"16","author":"IT Klip","year":"2014","unstructured":"Klip IT, Jankowska EA, Enjuanes C, Voors AA, Banasiak W, Bruguera J, Rozentryt P, Polonski L, van Veldhuisen DJ, Ponikowski P, Comin-Colet J, van der Meer P (2014) The additive burden of iron deficiency in the cardiorenal\u2013anaemia axis: scope of a problem and its consequences. Eur J Heart Fail 16(6):655\u2013662. https:\/\/doi.org\/10.1002\/ejhf.84","journal-title":"Eur J Heart Fail"},{"issue":"6","key":"3741_CR14","doi-asserted-by":"publisher","first-page":"716","DOI":"10.1002\/ejhf.531","volume":"18","author":"AA Voors","year":"2016","unstructured":"Voors AA, Anker SD, Cleland JG, Dickstein K, Filippatos G, van der Harst P, Hillege HL, Lang CC, Ter Maaten JM, Ng L, Ponikowski P, Samani NJ, van Veldhuisen DJ, Zannad F, Zwinderman AH, Metra M (2016) A systems BIOlogy Study to TAilored Treatment in Chronic Heart Failure: rationale, design, and baseline characteristics of BIOSTAT-CHF. Eur J Heart Fail 18(6):716\u2013726. https:\/\/doi.org\/10.1002\/ejhf.531","journal-title":"Eur J Heart Fail"},{"issue":"1","key":"3741_CR15","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1002\/ejhf.2393","volume":"24","author":"RIS Alnuwaysir","year":"2022","unstructured":"Alnuwaysir RIS, Grote Beverborg N, Hoes MF, Markousis-Mavrogenis G, Gomez KA, van der Wal HH, Cleland JGF, Dickstein K, Lang CC, Ng LL, Ponikowski P, Anker SD, van Veldhuisen DJ, Voors AA, van der Meer P (2022) Additional burden of iron deficiency in heart failure patients beyond the cardio-renal anaemia syndrome: findings from the BIOSTAT-CHF study. Eur J Heart Fail 24(1):192\u2013204. https:\/\/doi.org\/10.1002\/ejhf.2393","journal-title":"Eur J Heart Fail"},{"issue":"2","key":"3741_CR16","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1185\/03007990903512461","volume":"26","author":"IC Macdougall","year":"2010","unstructured":"Macdougall IC (2010) Iron supplementation in the non-dialysis chronic kidney disease (ND-CKD) patient: oral or intravenous? Curr Med Res Opin 26(2):473\u2013482. https:\/\/doi.org\/10.1185\/03007990903512461","journal-title":"Curr Med Res Opin"},{"issue":"4","key":"3741_CR17","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1053\/j.ackd.2019.05.002","volume":"26","author":"PE Pergola","year":"2019","unstructured":"Pergola PE, Fishbane S, Ganz T (2019) Novel oral iron therapies for iron deficiency anemia in chronic kidney disease. Adv Chronic Kidney Dis 26(4):272\u2013291. https:\/\/doi.org\/10.1053\/j.ackd.2019.05.002","journal-title":"Adv Chronic Kidney Dis"},{"issue":"11","key":"3741_CR18","doi-asserted-by":"publisher","first-page":"2075","DOI":"10.1093\/ndt\/gfu201","volume":"29","author":"IC Macdougall","year":"2014","unstructured":"Macdougall IC, Bock AH, Carrera F, Eckardt KU, Gaillard C, Van Wyck D, Roubert B, Nolen JG, Roger SD, Investigators F-CS (2014) FIND-CKD: a randomized trial of intravenous ferric carboxymaltose versus oral iron in patients with chronic kidney disease and iron deficiency anaemia. Nephrol Dial Transplant 29(11):2075\u20132084. https:\/\/doi.org\/10.1093\/ndt\/gfu201","journal-title":"Nephrol Dial Transplant"},{"issue":"8","key":"3741_CR19","doi-asserted-by":"publisher","first-page":"694","DOI":"10.1016\/j.cardfail.2015.05.006","volume":"21","author":"ED Niehaus","year":"2015","unstructured":"Niehaus ED, Malhotra R, Cocca-Spofford D, Semigran M, Lewis GD (2015) Repletion of iron stores with the use of oral iron supplementation in patients with systolic heart failure. J Card Fail 21(8):694\u2013697. https:\/\/doi.org\/10.1016\/j.cardfail.2015.05.006","journal-title":"J Card Fail"},{"issue":"19","key":"3741_CR20","doi-asserted-by":"publisher","first-page":"1958","DOI":"10.1001\/jama.2017.5427","volume":"317","author":"GD Lewis","year":"2017","unstructured":"Lewis GD, Malhotra R, Hernandez AF, McNulty SE, Smith A, Felker GM, Tang WHW, LaRue SJ, Redfield MM, Semigran MJ, Givertz MM, Van Buren P, Whellan D, Anstrom KJ, Shah MR, Desvigne-Nickens P, Butler J, Braunwald E, Network NHFCR (2017) Effect of oral iron repletion on exercise capacity in patients with heart failure with reduced ejection fraction and iron deficiency: the IRONOUT HF randomized clinical trial. JAMA 317(19):1958\u20131966. https:\/\/doi.org\/10.1001\/jama.2017.5427","journal-title":"JAMA"},{"issue":"2","key":"3741_CR21","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/j.jacc.2007.09.036","volume":"51","author":"DO Okonko","year":"2008","unstructured":"Okonko DO, Grzeslo A, Witkowski T, Mandal AK, Slater RM, Roughton M, Foldes G, Thum T, Majda J, Banasiak W, Missouris CG, Poole-Wilson PA, Anker SD, Ponikowski P (2008) Effect of intravenous iron sucrose on exercise tolerance in anemic and nonanemic patients with symptomatic chronic heart failure and iron deficiency FERRIC-HF: a randomized, controlled, observer-blinded trial. J Am Coll Cardiol 51(2):103\u2013112. https:\/\/doi.org\/10.1016\/j.jacc.2007.09.036","journal-title":"J Am Coll Cardiol"},{"issue":"25","key":"3741_CR22","doi-asserted-by":"publisher","first-page":"2436","DOI":"10.1056\/NEJMoa0908355","volume":"361","author":"SD Anker","year":"2009","unstructured":"Anker SD, Comin Colet J, Filippatos G, Willenheimer R, Dickstein K, Drexler H, Luscher TF, Bart B, Banasiak W, Niegowska J, Kirwan BA, Mori C, von Eisenhart RB, Pocock SJ, Poole-Wilson PA, Ponikowski P, Investigators F-HT (2009) Ferric carboxymaltose in patients with heart failure and iron deficiency. N Engl J Med 361(25):2436\u20132448. https:\/\/doi.org\/10.1056\/NEJMoa0908355","journal-title":"N Engl J Med"},{"issue":"1","key":"3741_CR23","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1002\/ehf2.12006","volume":"1","author":"P Ponikowski","year":"2014","unstructured":"Ponikowski P, van Veldhuisen DJ, Comin-Colet J, Ertl G, Komajda M, Mareev V, McDonagh TA, Parkhomenko A, Tavazzi L, Levesque V, Mori C, Roubert B, Filippatos G, Ruschitzka F, Anker SD (2014) Rationale and design of the CONFIRM-HF study: a double-blind, randomized, placebo-controlled study to assess the effects of intravenous ferric carboxymaltose on functional capacity in patients with chronic heart failure and iron deficiency. ESC Heart Fail 1(1):52\u201358. https:\/\/doi.org\/10.1002\/ehf2.12006","journal-title":"ESC Heart Fail"},{"issue":"11","key":"3741_CR24","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1093\/eurheartj\/ehu385","volume":"36","author":"P Ponikowski","year":"2015","unstructured":"Ponikowski P, van Veldhuisen DJ, Comin-Colet J, Ertl G, Komajda M, Mareev V, McDonagh T, Parkhomenko A, Tavazzi L, Levesque V, Mori C, Roubert B, Filippatos G, Ruschitzka F, Anker SD, Investigators C-H (2015) Beneficial effects of long-term intravenous iron therapy with ferric carboxymaltose in patients with symptomatic heart failure and iron deficiencydagger. Eur Heart J 36(11):657\u2013668. https:\/\/doi.org\/10.1093\/eurheartj\/ehu385","journal-title":"Eur Heart J"},{"issue":"10266","key":"3741_CR25","doi-asserted-by":"publisher","first-page":"1895","DOI":"10.1016\/S0140-6736(20)32339-4","volume":"396","author":"P Ponikowski","year":"2020","unstructured":"Ponikowski P, Kirwan BA, Anker SD, McDonagh T, Dorobantu M, Drozdz J, Fabien V, Filippatos G, Gohring UM, Keren A, Khintibidze I, Kragten H, Martinez FA, Metra M, Milicic D, Nicolau JC, Ohlsson M, Parkhomenko A, Pascual-Figal DA, Ruschitzka F, Sim D, Skouri H, van der Meer P, Lewis BS, Comin-Colet J, von Haehling S, Cohen-Solal A, Danchin N, Doehner W, Dargie HJ, Motro M, Butler J, Friede T, Jensen KH, Pocock S, Jankowska EA, AFFIRM-AHF Investigators (2020) Ferric carboxymaltose for iron deficiency at discharge after acute heart failure: a multicentre, double-blind, randomised, controlled trial. Lancet 396(10266):1895\u20131904. https:\/\/doi.org\/10.1016\/S0140-6736(20)32339-4","journal-title":"Lancet"},{"issue":"8","key":"3741_CR26","doi-asserted-by":"publisher","first-page":"1299","DOI":"10.1007\/s00392-021-01837-8","volume":"110","author":"FJ Graham","year":"2021","unstructured":"Graham FJ, Pellicori P, Ford I, Petrie MC, Kalra PR, Cleland JGF (2021) Intravenous iron for heart failure with evidence of iron deficiency: a meta-analysis of randomised trials. Clin Res Cardiol 110(8):1299\u20131307. https:\/\/doi.org\/10.1007\/s00392-021-01837-8","journal-title":"Clin Res Cardiol"},{"key":"3741_CR27","doi-asserted-by":"publisher","unstructured":"Kalra PR, Cleland JGF, Petrie MC, Thomson EA, Kalra PA, Squire IB, Ahmed FZ, Al-Mohammad A, Cowburn PJ, Foley PWX, Graham FJ, Japp AG, Lane RE, Lang NN, Ludman AJ, Macdougall IC, Pellicori P, Ray R, Robertson M, Seed A, Ford I, Group IS (2022) Intravenous ferric derisomaltose in patients with heart failure and iron deficiency in the UK (IRONMAN): an investigator-initiated, prospective, randomised, open-label, blinded-endpoint trial. Lancet 400(10369):2199\u20132209. https:\/\/doi.org\/10.1016\/S0140-6736(22)02083-9","DOI":"10.1016\/S0140-6736(22)02083-9"},{"issue":"2","key":"3741_CR28","doi-asserted-by":"publisher","first-page":"1473","DOI":"10.1002\/ehf2.14310","volume":"10","author":"HM Salah","year":"2023","unstructured":"Salah HM, Savarese G, Rosano GMC, Ambrosy AP, Mentz RJ, Fudim M (2023) Intravenous iron infusion in patients with heart failure: a systematic review and study-level meta-analysis. ESC Heart Fail 10(2):1473\u20131480. https:\/\/doi.org\/10.1002\/ehf2.14310","journal-title":"ESC Heart Fail"},{"key":"3741_CR29","doi-asserted-by":"publisher","unstructured":"Dhaliwal S, Kalogeropoulos AP (2023) Markers of iron metabolism and outcomes in patients with heart failure: a systematic review. Int J Mol Sci 24(6). https:\/\/doi.org\/10.3390\/ijms24065645","DOI":"10.3390\/ijms24065645"},{"issue":"Suppl 1","key":"3741_CR30","doi-asserted-by":"publisher","first-page":"i16","DOI":"10.1093\/ckj\/sfx043","volume":"10","author":"IC Macdougall","year":"2017","unstructured":"Macdougall IC (2017) Intravenous iron therapy in patients with chronic kidney disease: recent evidence and future directions. Clin Kidney J 10(Suppl 1):i16\u2013i24. https:\/\/doi.org\/10.1093\/ckj\/sfx043","journal-title":"Clin Kidney J"},{"issue":"7","key":"3741_CR31","doi-asserted-by":"publisher","first-page":"686","DOI":"10.1016\/j.hlc.2014.12.161","volume":"24","author":"JE Toblli","year":"2015","unstructured":"Toblli JE, Di Gennaro F, Rivas C (2015) Changes in echocardiographic parameters in iron deficiency patients with heart failure and chronic kidney disease treated with intravenous iron. Heart Lung Circ 24(7):686\u2013695. https:\/\/doi.org\/10.1016\/j.hlc.2014.12.161","journal-title":"Heart Lung Circ"},{"issue":"3","key":"3741_CR32","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1002\/ejhf.229","volume":"17","author":"P Ponikowski","year":"2015","unstructured":"Ponikowski P, Filippatos G, Colet JC, Willenheimer R, Dickstein K, Luscher T, Gaudesius G, von Eisenhart RB, Mori C, Greenlaw N, Ford I, Macdougall I, Anker SD, Investigators F-HT (2015) The impact of intravenous ferric carboxymaltose on renal function: an analysis of the FAIR-HF study. Eur J Heart Fail 17(3):329\u2013339. https:\/\/doi.org\/10.1002\/ejhf.229","journal-title":"Eur J Heart Fail"},{"key":"3741_CR33","doi-asserted-by":"publisher","unstructured":"Alnuwaysir RIS, Hoes MF, van Veldhuisen DJ, van der Meer P, Grote Beverborg N (2021) Iron deficiency in heart failure: mechanisms and pathophysiology. J Clin Med 11(1). https:\/\/doi.org\/10.3390\/jcm11010125","DOI":"10.3390\/jcm11010125"},{"issue":"1","key":"3741_CR34","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1007\/BF02829934","volume":"1","author":"G Cairo","year":"2006","unstructured":"Cairo G, Bernuzzi F, Recalcati S (2006) A precious metal: iron, an essential nutrient for all cells. Genes Nutr 1(1):25\u201339. https:\/\/doi.org\/10.1007\/BF02829934","journal-title":"Genes Nutr"},{"key":"3741_CR35","unstructured":"Universit\u00e4tsklinikum H-E, Deutsches Zentrum f\u00fcr H-K-F, Charite University BG (2024) Intravenous iron in patients with systolic heart failure and iron deficiency to improve morbidity & mortality. https:\/\/clinicaltrials.gov\/show\/NCT03036462"},{"key":"3741_CR36","doi-asserted-by":"publisher","unstructured":"Mentz RJ, Ambrosy AP, Ezekowitz JA, Lewis GD, Butler J, Wong YW, De Pasquale CG, Troughton RW, O'Meara E, Rockhold FW, Garg J, Samsky MD, Leloudis D, Dugan M, Mundy LM, Hernandez AF, Investigators H-FT (2021) Randomized placebo-controlled trial of ferric carboxymaltose in heart failure with iron deficiency: rationale and design. Circ Heart Fail 14(5):e008100. https:\/\/doi.org\/10.1161\/CIRCHEARTFAILURE.120.008100","DOI":"10.1161\/CIRCHEARTFAILURE.120.008100"},{"key":"3741_CR37","unstructured":"Charite University BG, University of G (2020) Effect of IV iron in patients with heart failure with preserved ejection fraction. https:\/\/clinicaltrials.gov\/show\/NCT03074591"},{"key":"3741_CR38","doi-asserted-by":"publisher","unstructured":"Vinke JS, Eisenga MF, Sanders JF, Berger SP, Spikman JM, Abdulahad WH, Bakker SJ, Gaillard C, van Zuilen AD, van der Meer P, de Borst MH (2023) Effect of intravenous ferric carboxymaltose on exercise capacity after kidney transplantation (EFFECT-KTx): rationale and study protocol for a double-blind, randomised, placebo-controlled trial. BMJ Open 13(3):e065423. https:\/\/doi.org\/10.1136\/bmjopen-2022-065423","DOI":"10.1136\/bmjopen-2022-065423"},{"key":"3741_CR39","doi-asserted-by":"publisher","unstructured":"Shah AA, Donovan K, Seeley C, Dickson EA, Palmer AJR, Doree C, Brunskill S, Reid J, Acheson AG, Sugavanam A, Litton E, Stanworth SJ (2021) Risk of infection associated with administration of intravenous iron: a systematic review and meta-analysis. JAMA Netw Open 4(11):e2133935. https:\/\/doi.org\/10.1001\/jamanetworkopen.2021.33935","DOI":"10.1001\/jamanetworkopen.2021.33935"},{"key":"3741_CR40","doi-asserted-by":"publisher","unstructured":"Rund D (2021) Intravenous iron and infection risk-still an unanswered question. JAMA Netw Open 4(11):e2134453. https:\/\/doi.org\/10.1001\/jamanetworkopen.2021.34453","DOI":"10.1001\/jamanetworkopen.2021.34453"},{"issue":"5","key":"3741_CR41","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1056\/NEJMoa1810742","volume":"380","author":"IC Macdougall","year":"2019","unstructured":"Macdougall IC, White C, Anker SD, Bhandari S, Farrington K, Kalra PA, McMurray JJV, Murray H, Tomson CRV, Wheeler DC, Winearls CG, Ford I, PIVOTAL Investigators and Committees (2019) Intravenous iron in patients undergoing maintenance hemodialysis. N Engl J Med 380(5):447\u2013458. https:\/\/doi.org\/10.1056\/NEJMoa1810742","journal-title":"N Engl J Med"}],"container-title":["International Urology and Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11255-023-03741-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11255-023-03741-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11255-023-03741-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,24]],"date-time":"2024-01-24T17:12:27Z","timestamp":1706116347000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11255-023-03741-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,22]]},"references-count":41,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2024,2]]}},"alternative-id":["3741"],"URL":"https:\/\/doi.org\/10.1007\/s11255-023-03741-8","relation":{},"ISSN":["1573-2584"],"issn-type":[{"type":"electronic","value":"1573-2584"}],"subject":[],"published":{"date-parts":[[2023,8,22]]},"assertion":[{"value":"15 June 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 August 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 August 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no competing interests to declare that are relevant to the content of this article.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}