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Demographic, preoperative laboratory data, stone characteristics, and intraoperative and postoperative data were gathered. Perioperative AKI had been defined as an elevation in serum creatinine by\u2009\u2265\u20090.3 mg\/dl within 48\u00a0h, or\u2009\u2265\u20091.5 times baseline, or urine volume less than 0.5\u00a0ml\/ kg\/hour for 6\u00a0hours. A multivariate logistic regression analysis was performed to determine the predictive factors of AKI. ROC curves were utilized to determine the cutoff values of the risk variables. P-values were deemed statistically significant when they were less than 0.05.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>A total of 418 participants had been involved. The frequency of AKI was 13.9, and 17.2% of patients with AKI developed CKD. The risk factors were age\u2009&gt;\u200946.5 years, smoking, BMI\u2009&gt;\u200928.5 kg\/m<jats:sup>2<\/jats:sup>, hypertension, diabetes, utilization of angiotensin-converting enzyme inhibitors (ACEI), haemoglobin\u2009&lt;\u200910.8 gm\/dl, baseline creatinine\u2009&gt;\u20091.41 mg\/dl, eGFR\u2009&lt;\u200965.2 ml\/min.\/1.73 m<jats:sup>2<\/jats:sup>, serum uric acid\u2009&gt;\u20095.2 mg\/dl, stone volume\u2009&gt;\u20091748 mm<jats:sup>3<\/jats:sup>, large tract size, long operative time, and intra-operative bleeding. Patients with AKI had a notably extended duration of hospitalization (3.2 days\u2009\u00b1\u20090.45 vs 2.1\u2009\u00b1\u20090.42, p\u2009&lt;\u20090.001).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Perioperative AKI occurred in 13.9% of individuals undergoing PNL. Identification and optimization of the risk factors and meticulous technique during PNL procedures should be attempted to decrease the risk of AKI.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s11255-024-03960-7","type":"journal-article","created":{"date-parts":[[2024,1,30]],"date-time":"2024-01-30T14:02:52Z","timestamp":1706623372000},"page":"1843-1850","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Predictors of acute kidney injury after percutaneous nephrolithotomy in adult patients: prospective observational study"],"prefix":"10.1007","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5530-8860","authenticated-orcid":false,"given":"Ahmed Mahmoud","family":"Hasan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed Mahmoud","family":"Riyad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mostafa AbdelRazek","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,1,30]]},"reference":[{"key":"3960_CR1","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1007\/s00240-007-0112-6","volume":"35","author":"PJ Olbert","year":"2007","unstructured":"Olbert PJ, Hegele A, Schrader AJ et al (2007) Pre and perioperative predictors of short-term clinical outcomes in patients undergoing percutaneous nephrolitholapaxy. 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