{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T02:35:49Z","timestamp":1755225349139,"version":"3.43.0"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2025,4,5]],"date-time":"2025-04-05T00:00:00Z","timestamp":1743811200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,4,5]],"date-time":"2025-04-05T00:00:00Z","timestamp":1743811200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Urol Nephrol"],"DOI":"10.1007\/s11255-025-04494-2","type":"journal-article","created":{"date-parts":[[2025,4,5]],"date-time":"2025-04-05T23:43:58Z","timestamp":1743896638000},"page":"3019-3028","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The relationship between serum salusins levels and atherosclerosis, endothelial dysfunction and cardiac morphology in autosomal dominant polycystic kidney disease"],"prefix":"10.1007","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0439-0590","authenticated-orcid":false,"given":"Sumeyye Elif","family":"Akti","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8489-4985","authenticated-orcid":false,"given":"Ibrahim","family":"Dogan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2025-2013","authenticated-orcid":false,"given":"Baris","family":"Eser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2444-7523","authenticated-orcid":false,"given":"Mucahit","family":"Yetim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3922-4517","authenticated-orcid":false,"given":"H\u00fcseyin","family":"Kayadibi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,4,5]]},"reference":[{"issue":"1","key":"4494_CR1","doi-asserted-by":"publisher","first-page":"10","DOI":"10.3810\/pgm.2010.01.2091","volume":"122","author":"M Cobble","year":"2010","unstructured":"Cobble M, Bale B (2010) Carotid intima-media thickness: knowledge and application to everyday practice. Postgrad Med 122(1):10\u201318. https:\/\/doi.org\/10.3810\/pgm.2010.01.2091","journal-title":"Postgrad Med"},{"issue":"2","key":"4494_CR2","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1038\/ki.2009.128","volume":"76","author":"VE Torres","year":"2009","unstructured":"Torres VE, Harris PC (2009) Autosomal dominant polycystic kidney disease: the last 3 years. Kidney Int 76(2):149\u2013168. https:\/\/doi.org\/10.1038\/ki.2009.128","journal-title":"Kidney Int"},{"issue":"1","key":"4494_CR3","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1681\/ASN.2017050483","volume":"29","author":"E Cornec-Le Gall","year":"2018","unstructured":"Cornec-Le Gall E, Torres VE, Harris PC (2018) Genetic complexity of autosomal dominant polycystic kidney and liver diseases. J Am Soc Nephrol 29(1):13\u201323. https:\/\/doi.org\/10.1681\/ASN.2017050483","journal-title":"J Am Soc Nephrol"},{"issue":"4","key":"4494_CR4","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1038\/nrneph.2009.13","volume":"5","author":"T Ecder","year":"2009","unstructured":"Ecder T, Schrier RW (2009) Cardiovascular abnormalities in autosomal-dominant polycystic kidney disease. Nat Rev Nephrol 5(4):221\u2013228. https:\/\/doi.org\/10.1038\/nrneph.2009.13","journal-title":"Nat Rev Nephrol"},{"issue":"3","key":"4494_CR5","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1159\/000354236","volume":"38","author":"KM Peterson","year":"2013","unstructured":"Peterson KM, Franchi F, Loeffler DL et al (2013) Endothelial dysfunction occurs prior to clinical evidence of polycystic kidney disease. Am J Nephrol 38(3):233\u2013240. https:\/\/doi.org\/10.1159\/000354236","journal-title":"Am J Nephrol"},{"issue":"9","key":"4494_CR6","doi-asserted-by":"publisher","first-page":"1166","DOI":"10.1038\/nm913","volume":"9","author":"M Shichiri","year":"2003","unstructured":"Shichiri M, Ishimaru S, Ota T, Nishikawa T, Isogai T, Hirata Y (2003) Salusins: newly identified bioactive peptides with hemodynamic and mitogenic activities. Nat Med 9(9):1166\u20131172. https:\/\/doi.org\/10.1038\/nm913","journal-title":"Nat Med"},{"issue":"1","key":"4494_CR7","first-page":"33","volume":"26","author":"S Ayd\u0131n","year":"2014","unstructured":"Ayd\u0131n S, Eren MN (2014) Physiology and clinical role of salusin-\u03b1 and salusin-\u03b2 in the cardiovascular system. Turkiye Klinikleri J Cardiovasc Sci 26(1):33\u201338","journal-title":"Turkiye Klinikleri J Cardiovasc Sci"},{"issue":"5","key":"4494_CR8","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1016\/j.jash.2011.06.003","volume":"5","author":"T Watanabe","year":"2011","unstructured":"Watanabe T, Sato K, Itoh F et al (2011) The roles of salusins in atherosclerosis and related cardiovascular diseases. J Am Soc Hypertens 5(5):359\u2013365. https:\/\/doi.org\/10.1016\/j.jash.2011.06.003","journal-title":"J Am Soc Hypertens"},{"issue":"1\u20133","key":"4494_CR9","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1016\/j.regpep.2010.03.009","volume":"162","author":"S Kimoto","year":"2010","unstructured":"Kimoto S, Sato K, Watanabe T, Suguro T, Koyama T, Shichiri M (2010) Serum levels and urinary excretion of salusin-alpha in renal insufficiency. Regul Pept 162(1\u20133):129\u2013132. https:\/\/doi.org\/10.1016\/j.regpep.2010.03.009","journal-title":"Regul Pept"},{"issue":"5","key":"4494_CR10","doi-asserted-by":"publisher","first-page":"638","DOI":"10.1161\/CIRCULATIONAHA.107.712539","volume":"117","author":"T Watanabe","year":"2008","unstructured":"Watanabe T, Nishio K, Kanome T et al (2008) Impact of salusin-alpha and -beta on human macrophage foam cell formation and coronary atherosclerosis. Circulation 117(5):638\u2013648. https:\/\/doi.org\/10.1161\/CIRCULATIONAHA.107.712539","journal-title":"Circulation"},{"issue":"9","key":"4494_CR11","doi-asserted-by":"publisher","first-page":"1003","DOI":"10.1517\/14728222.2013.819852","volume":"17","author":"M Masumura","year":"2013","unstructured":"Masumura M, Watanabe R, Nagashima A et al (2013) Anti-salusin-beta antibody enhances angiogenesis after myocardial ischemia reperfusion injury. Expert Opin Ther Targ 17(9):1003\u20131009. https:\/\/doi.org\/10.1517\/14728222.2013.819852","journal-title":"Expert Opin Ther Targ"},{"issue":"6","key":"4494_CR12","doi-asserted-by":"publisher","first-page":"1003","DOI":"10.2215\/CJN.06870909","volume":"5","author":"WM Michels","year":"2010","unstructured":"Michels WM, Grootendorst DC, Verduijn M, Elliott EG, Dekker FW, Krediet RT (2010) Performance of the Cockcroft-Gault, MDRD, and new CKD-EPI formulas in relation to GFR, age, and body size. Clin J Am Soc Nephrol 5(6):1003\u20131009. https:\/\/doi.org\/10.2215\/CJN.06870909","journal-title":"Clin J Am Soc Nephrol"},{"key":"4494_CR13","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/965140","author":"K Sato","year":"2013","unstructured":"Sato K, Watanabe R, Itoh F, Shichiri M, Watanabe T (2013) Salusins: potential use as a biomarker for atherosclerotic cardiovascular diseases. Int J Hypertens. https:\/\/doi.org\/10.1155\/2013\/965140","journal-title":"Int J Hypertens"},{"issue":"1","key":"4494_CR14","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1016\/j.atherosclerosis.2010.04.027","volume":"212","author":"M Nagashima","year":"2010","unstructured":"Nagashima M, Watanabe T, Shiraishi Y et al (2010) Chronic infusion of salusin-alpha and -beta exerts opposite effects on atherosclerotic lesion development in apolipoprotein E-deficient mice. Atherosclerosis 212(1):70\u201377. https:\/\/doi.org\/10.1016\/j.atherosclerosis.2010.04.027","journal-title":"Atherosclerosis"},{"issue":"4","key":"4494_CR15","doi-asserted-by":"publisher","first-page":"210","DOI":"10.11622\/smedj.2018123","volume":"60","author":"S Sipahi","year":"2019","unstructured":"Sipahi S, Genc AB, Acikgoz SB et al (2019) Relationship of salusin-alpha and salusin-beta levels with atherosclerosis in patients undergoing haemodialysis. Singapore Med J 60(4):210\u2013215. https:\/\/doi.org\/10.11622\/smedj.2018123","journal-title":"Singapore Med J"},{"issue":"6","key":"4494_CR16","doi-asserted-by":"publisher","first-page":"1349","DOI":"10.1681\/ASN.V561349","volume":"5","author":"AB Chapman","year":"1994","unstructured":"Chapman AB, Johnson AM, Gabow PA, Schrier RW (1994) Overt proteinuria and microalbuminuria in autosomal dominant polycystic kidney disease. J Am Soc Nephrol 5(6):1349\u20131354. https:\/\/doi.org\/10.1681\/ASN.V561349","journal-title":"J Am Soc Nephrol"},{"key":"4494_CR17","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/876865","volume":"2013","author":"T Takenaka","year":"2013","unstructured":"Takenaka T, Takane H, Kikuta T, Watanabe Y, Suzuki H (2013) Statin improves flow-mediated vasodilation in chronic kidney diseases. Int J Hypertens 2013:876865. https:\/\/doi.org\/10.1155\/2013\/876865","journal-title":"Int J Hypertens"},{"issue":"16","key":"4494_CR18","doi-asserted-by":"publisher","first-page":"1091","DOI":"10.1056\/NEJM199010183231602","volume":"323","author":"AB Chapman","year":"1990","unstructured":"Chapman AB, Johnson A, Gabow PA, Schrier RW (1990) The renin-angiotensin-aldosterone system and autosomal dominant polycystic kidney disease. N Engl J Med 323(16):1091\u20131096. https:\/\/doi.org\/10.1056\/NEJM199010183231602","journal-title":"N Engl J Med"},{"issue":"1","key":"4494_CR19","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1681\/ASN.V121194","volume":"12","author":"T Ecder","year":"2001","unstructured":"Ecder T, Schrier RW (2001) Hypertension in autosomal-dominant polycystic kidney disease: early occurrence and unique aspects. J Am Soc Nephrol 12(1):194\u2013200. https:\/\/doi.org\/10.1681\/ASN.V121194","journal-title":"J Am Soc Nephrol"},{"issue":"2","key":"4494_CR20","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1136\/hrt.2004.042473","volume":"91","author":"T Kahan","year":"2005","unstructured":"Kahan T, Bergfeldt L (2005) Left ventricular hypertrophy in hypertension: its arrhythmogenic potential. Heart 91(2):250\u2013256. https:\/\/doi.org\/10.1136\/hrt.2004.042473","journal-title":"Heart"},{"issue":"5","key":"4494_CR21","doi-asserted-by":"publisher","first-page":"1311","DOI":"10.1038\/ki.1992.195","volume":"41","author":"PA Gabow","year":"1992","unstructured":"Gabow PA, Johnson AM, Kaehny WD et al (1992) Factors affecting the progression of renal disease in autosomal-dominant polycystic kidney disease. Kidney Int 41(5):1311\u20131319. https:\/\/doi.org\/10.1038\/ki.1992.195","journal-title":"Kidney Int"},{"issue":"5","key":"4494_CR22","doi-asserted-by":"publisher","first-page":"2244","DOI":"10.1111\/j.1523-1755.2005.00682.x","volume":"8","author":"H Oflaz","year":"2005","unstructured":"Oflaz H, Alisir S, Buyukaydin B et al (2005) Biventricular diastolic dysfunction in patients with autosomal-dominant polycystic kidney disease. Kidney Int 8(5):2244\u20132249. https:\/\/doi.org\/10.1111\/j.1523-1755.2005.00682.x","journal-title":"Kidney Int"},{"issue":"10","key":"4494_CR23","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1038\/jhh.2011.71","volume":"26","author":"Y Ti","year":"2012","unstructured":"Ti Y, Wang F, Wang ZH et al (2012) Associations of serum salusin-alpha levels with atherosclerosis and left ventricular diastolic dysfunction in essential hypertension. J Hum Hypertens 26(10):603\u2013609. https:\/\/doi.org\/10.1038\/jhh.2011.71","journal-title":"J Hum Hypertens"},{"issue":"3","key":"4494_CR24","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1056\/NEJMoa1012592","volume":"365","author":"JF Polak","year":"2011","unstructured":"Polak JF, Pencina MJ, Pencina KM, O\u2019Donnell CJ, Wolf PA, D\u2019Agostino RB Sr (2011) Carotid-wall intima-media thickness and cardiovascular events. N Engl J Med 365(3):213\u2013221. https:\/\/doi.org\/10.1056\/NEJMoa1012592","journal-title":"N Engl J Med"},{"issue":"5","key":"4494_CR25","doi-asserted-by":"publisher","first-page":"854","DOI":"10.1053\/j.ajkd.2004.01.011","volume":"43","author":"O Kocaman","year":"2004","unstructured":"Kocaman O, Oflaz H, Yekeler E et al (2004) Endothelial dysfunction and increased carotid intima-media thickness in patients with autosomal dominant polycystic kidney disease. Am J Kidney Dis 43(5):854\u2013860. https:\/\/doi.org\/10.1053\/j.ajkd.2004.01.011","journal-title":"Am J Kidney Dis"},{"issue":"4","key":"4494_CR26","doi-asserted-by":"publisher","first-page":"986","DOI":"10.2215\/CJN.02330607","volume":"3","author":"K Turkmen","year":"2008","unstructured":"Turkmen K, Oflaz H, Uslu B et al (2008) Coronary flow velocity reserve and carotid intima media thickness in patients with autosomal dominant polycystic kidney disease: from impaired tubules to impaired carotid and coronary arteries. Clin J Am Soc Nephrol 3(4):986\u2013991. https:\/\/doi.org\/10.2215\/CJN.02330607","journal-title":"Clin J Am Soc Nephrol"},{"issue":"4","key":"4494_CR27","doi-asserted-by":"publisher","DOI":"10.1111\/ijcp.13721","volume":"75","author":"I Bellos","year":"2021","unstructured":"Bellos I, Kontzoglou K, Perrea DN (2021) Markers of endothelial dysfunction and arterial stiffness in patients with early-stage autosomal dominant polycystic kidney disease: a meta-analysis. Int J Clin Pract 75(4):e13721. https:\/\/doi.org\/10.1111\/ijcp.13721","journal-title":"Int J Clin Pract"},{"issue":"6","key":"4494_CR28","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1093\/oxfordjournals.aje.a009302","volume":"146","author":"LE Chambless","year":"1997","unstructured":"Chambless LE, Heiss G, Folsom AR et al (1997) Association of coronary heart disease incidence with carotid arterial wall thickness and major risk factors: the Atherosclerosis Risk in Communities (ARIC) Study, 1987\u20131993. Am J Epidemiol 146(6):483\u2013494. https:\/\/doi.org\/10.1093\/oxfordjournals.aje.a009302","journal-title":"Am J Epidemiol"}],"container-title":["International Urology and Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11255-025-04494-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11255-025-04494-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11255-025-04494-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,13]],"date-time":"2025-08-13T10:07:54Z","timestamp":1755079674000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11255-025-04494-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,5]]},"references-count":28,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2025,9]]}},"alternative-id":["4494"],"URL":"https:\/\/doi.org\/10.1007\/s11255-025-04494-2","relation":{},"ISSN":["1573-2584"],"issn-type":[{"type":"electronic","value":"1573-2584"}],"subject":[],"published":{"date-parts":[[2025,4,5]]},"assertion":[{"value":"23 December 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 March 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 April 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}