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The manual procedure was performed by two expert physiotherapists with a certification in osteopathic manipulation, following a consensus training. We assessed symptom severity and psychosocial variables using the NIH Chronic Prostatitis Symptom Index (NIH-CPSI), the Hospital Anxiety and Depression Scale (HADS), and the Fear Avoidance Belief Questionnaire (FABQ). Correlation analyses explored relationships between APFs, the presence of pain, and psychosocial variables.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      APFs were significantly associated with CPP\/CPPS, particularly in the sacrococcygeal (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.609,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01) and pelvic floor (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.620,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01) regions, indicating a moderate-to-strong correlation. The multivariate analysis confirmed that sacrococcygeal APFs (OR 3.02, 95% CI 1.96\u20134.65,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and pelvic floor APFs (OR 2.99, 95% CI 1.87\u20134.78,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) were independently associated with CPP\/CPPS, whereas sacroiliac findings showed a weak correlation. The correlations between APFs and psychosocial issues (anxiety, depression, fear-avoidance) were weak (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.25).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Sacrococcygeal and pelvic floor APFs appear to be important clinical markers of CPP\/CPPS. Their presence may help identify patients who could benefit from targeted manual therapy as part of multimodal management. Further research should evaluate the prognostic value of these findings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s11255-025-04521-2","type":"journal-article","created":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T07:48:41Z","timestamp":1745567321000},"page":"3521-3531","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The presence of abnormal palpatory findings in the sacrococcygeal area is correlated with chronic pelvic pain: a cross-sectional study"],"prefix":"10.1007","volume":"57","author":[{"given":"Daniele","family":"Origo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fulvio","family":"Dal Farra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Tramontano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,4,25]]},"reference":[{"issue":"1","key":"4521_CR1","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/j.eururo.2009.08.020","volume":"57","author":"M Fall","year":"2010","unstructured":"Fall M, Baranowski AP, Elneil S, Engeler D, Hughes J, Messelink EJ, Oberpenning F, Williams ACDC, European Association of Urology (2010) EAU guidelines on chronic pelvic pain. 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