{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T14:37:34Z","timestamp":1777300654293,"version":"3.51.4"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T00:00:00Z","timestamp":1762300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T00:00:00Z","timestamp":1762300800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Urol Nephrol"],"DOI":"10.1007\/s11255-025-04884-6","type":"journal-article","created":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T10:38:23Z","timestamp":1762339103000},"page":"1727-1733","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The diagnostic value of native and early post-contrast CT attenuation in differentiating benign from potentially malignant adrenal lesions"],"prefix":"10.1007","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-4290-5849","authenticated-orcid":false,"given":"Haris","family":"\u0110ug","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-8112-234X","authenticated-orcid":false,"given":"Davor","family":"Ivani\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-4026-4384","authenticated-orcid":false,"given":"Faris","family":"Tursi\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-1277-445X","authenticated-orcid":false,"given":"Ivana","family":"\u010cerkez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0525-3288","authenticated-orcid":false,"given":"Samir","family":"Delibegovi\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,11,5]]},"reference":[{"key":"4884_CR1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-025-17296-8","author":"L Owei","year":"2025","unstructured":"Owei L, Wachtel H (2025) The landmark series: evaluation and management of adrenal incidentalomas. Ann Surg Oncol. https:\/\/doi.org\/10.1245\/s10434-025-17296-8","journal-title":"Ann Surg Oncol"},{"key":"4884_CR2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1530\/EJE-16-0467","volume":"175","author":"M Fassnacht","year":"2016","unstructured":"Fassnacht M, Arlt W, Bancos I, Dralle H, Newell-Price J, Sahdev A et al (2016) Management of adrenal incidentalomas: European Society of Endocrinology Clinical Practice Guideline in collaboration with the European Network for the Study of Adrenal Tumors. Eur J Endocrinol 175:1\u201334. https:\/\/doi.org\/10.1530\/EJE-16-0467","journal-title":"Eur J Endocrinol"},{"key":"4884_CR3","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.23.30769","volume":"222","author":"MT Corwin","year":"2024","unstructured":"Corwin MT, Caoili EM, Elsayes KM, Garratt J, Hackett CE, Hudson E et al (2024) Performance of CT with adrenal-washout protocol in heterogeneous adrenal nodules: a multiinstitutional study. Am J Roentgenol 222:e2330769. https:\/\/doi.org\/10.2214\/AJR.23.30769","journal-title":"Am J Roentgenol"},{"key":"4884_CR4","doi-asserted-by":"publisher","DOI":"10.5306\/wjco.v16.i6.106511","volume":"16","author":"I Ilias","year":"2025","unstructured":"Ilias I, Meristoudis G (2025) Changing paradigms in evaluating adrenal incidentalomas: Bayesian evaluation of [18F]Fluorodeoxyglucose positron emission tomography use, honed on adrenocortical carcinoma. World J Clin Oncol 16:106511. https:\/\/doi.org\/10.5306\/wjco.v16.i6.106511","journal-title":"World J Clin Oncol"},{"key":"4884_CR5","doi-asserted-by":"publisher","first-page":"1206","DOI":"10.2214\/AJR.16.17758","volume":"208","author":"N Schieda","year":"2017","unstructured":"Schieda N, Siegelman ES (2017) Update on CT and MRI of adrenal nodules. Am J Roentgenol 208:1206\u20131217. https:\/\/doi.org\/10.2214\/AJR.16.17758","journal-title":"Am J Roentgenol"},{"key":"4884_CR6","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1016\/j.crad.2020.12.012","volume":"76","author":"F Zhu","year":"2021","unstructured":"Zhu F, Zhu X, Shi H, Liu C, Xu Z, Shao M et al (2021) Adrenal metastases: early biphasic contrast-enhanced CT findings with emphasis on differentiation from lipid-poor adrenal adenomas. Clin Radiol 76:294\u2013301. https:\/\/doi.org\/10.1016\/j.crad.2020.12.012","journal-title":"Clin Radiol"},{"issue":"2","key":"4884_CR7","doi-asserted-by":"publisher","first-page":"W109","DOI":"10.2214\/AJR.17.19103","volume":"211","author":"CS Ng","year":"2018","unstructured":"Ng CS, Altinmakas E, Wei W, Ghosh P, Li X, Grubbs EG et al (2018) Utility of intermediate-delay washout CT images for differentiation of malignant and benign adrenal lesions: a multivariate analysis. Am J Roentgenol 211(2):W109\u2013W115","journal-title":"Am J Roentgenol"},{"key":"4884_CR8","doi-asserted-by":"publisher","first-page":"96","DOI":"10.5152\/tud.2023.22245","volume":"49","author":"BS Jackson","year":"2023","unstructured":"Jackson BS (2023) Adrenal incidentaloma controversial size recommendations. Urol Res Pract 49:96\u201399. https:\/\/doi.org\/10.5152\/tud.2023.22245","journal-title":"Urol Res Pract"},{"key":"4884_CR9","doi-asserted-by":"publisher","first-page":"628","DOI":"10.1097\/RCT.0000000000000578","volume":"41","author":"SC Azoury","year":"2017","unstructured":"Azoury SC, Nagarajan N, Young A, Mathur A, Prescott JD, Fishman EK et al (2017) Computed tomography in the management of adrenal tumors: does size still matter? J Comput Assist Tomogr 41:628\u2013632. https:\/\/doi.org\/10.1097\/RCT.0000000000000578","journal-title":"J Comput Assist Tomogr"},{"key":"4884_CR10","doi-asserted-by":"publisher","first-page":"373","DOI":"10.3803\/EnM.2023.1779","volume":"38","author":"SS Park","year":"2023","unstructured":"Park SS, Kim JH (2023) Recent updates on the management of adrenal incidentalomas. Endocrinol Metab 38:373\u2013380. https:\/\/doi.org\/10.3803\/EnM.2023.1779","journal-title":"Endocrinol Metab"},{"key":"4884_CR11","doi-asserted-by":"publisher","first-page":"967","DOI":"10.1016\/j.path.2019.08.005","volume":"12","author":"A Hodgson","year":"2019","unstructured":"Hodgson A, Pakbaz S, Mete O (2019) A diagnostic approach to adrenocortical tumors. Surg Pathol Clin 12:967\u2013995. https:\/\/doi.org\/10.1016\/j.path.2019.08.005","journal-title":"Surg Pathol Clin"},{"key":"4884_CR12","doi-asserted-by":"publisher","first-page":"1484","DOI":"10.2214\/AJR.09.3636","volume":"194","author":"G Foti","year":"2010","unstructured":"Foti G, Faccioli N, Manfredi R, Mantovani W, Mucelli RP (2010) Evaluation of relative wash-in ratio of adrenal lesions at early biphasic CT. Am J Roentgenol 194:1484\u20131491. https:\/\/doi.org\/10.2214\/AJR.09.3636","journal-title":"Am J Roentgenol"},{"key":"4884_CR13","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1016\/j.jacr.2021.08.010","volume":"18","author":"RN Mody","year":"2021","unstructured":"Mody RN, Remer EM, Nikolaidis P, Khatri G, Dogra VS, Ganeshan D et al (2021) ACR appropriateness criteria for adrenal mass evaluation: 2021 update. J Am Coll Radiol 18:251\u2013267. https:\/\/doi.org\/10.1016\/j.jacr.2021.08.010","journal-title":"J Am Coll Radiol"},{"key":"4884_CR14","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics12092171","volume":"12","author":"B Bracci","year":"2022","unstructured":"Bracci B, De Santis D, Del Gaudio A, Faugno MC, Romano A, Tarallo M et al (2022) Adrenal lesions: a review of imaging. Diagnostics 12:2171. https:\/\/doi.org\/10.3390\/diagnostics12092171","journal-title":"Diagnostics"},{"key":"4884_CR15","doi-asserted-by":"publisher","first-page":"154","DOI":"10.4274\/haseki.galenos.2024.9816","volume":"62","author":"H Ozgul","year":"2024","unstructured":"Ozgul H, Yildiz TC, Cakir RC, Canturk S, Celik O, Yur M (2024) The significance of Hounsfield unit and tumor diameter in the differentiation of malignant and benign adrenal masses. Med Bull Haseki 62:154\u2013160. https:\/\/doi.org\/10.4274\/haseki.galenos.2024.9816","journal-title":"Med Bull Haseki"},{"key":"4884_CR16","doi-asserted-by":"publisher","DOI":"10.3390\/cancers17050849","volume":"17","author":"G Grazzini","year":"2025","unstructured":"Grazzini G, Pradella S, De Litteris F, Galluzzo A, Anichini M, Treballi F et al (2025) Adrenal mass evaluation: suspicious radiological signs of malignancy. Cancers 17:849. https:\/\/doi.org\/10.3390\/cancers17050849","journal-title":"Cancers"},{"key":"4884_CR17","doi-asserted-by":"publisher","first-page":"637","DOI":"10.3897\/folmed.66.e130680","volume":"66","author":"K Tsalis","year":"2024","unstructured":"Tsalis K, Ioannidis O, Savvala NA, Gkasdaris G, Christidis P, Anestiadou E et al (2024) Thoracoabdominal approach to large adrenal tumors - when laparoscopic adrenalectomy is not enough: a retrospective four-year study. Folia Med 66:637\u2013644. https:\/\/doi.org\/10.3897\/folmed.66.e130680","journal-title":"Folia Med"},{"issue":"1","key":"4884_CR18","doi-asserted-by":"publisher","DOI":"10.1186\/s12880-025-01842-7","volume":"25","author":"Y Chao","year":"2025","unstructured":"Chao Y, Zhu H, Yang W, Yao H, Ma N, Chen X et al (2025) Differentiating between adrenocortical carcinoma and pheochromocytoma by a CT-based radiomics model: a multicenter retrospective study. BMC Med Imaging 25(1):310. https:\/\/doi.org\/10.1186\/s12880-025-01842-7","journal-title":"BMC Med Imaging"}],"container-title":["International Urology and Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11255-025-04884-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11255-025-04884-6","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11255-025-04884-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T13:41:59Z","timestamp":1777297319000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11255-025-04884-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,5]]},"references-count":18,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2026,5]]}},"alternative-id":["4884"],"URL":"https:\/\/doi.org\/10.1007\/s11255-025-04884-6","relation":{},"ISSN":["1573-2584"],"issn-type":[{"value":"1573-2584","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,5]]},"assertion":[{"value":"29 September 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 October 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 November 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no competing interests to declare that are relevant to the content of this article.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}