{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T10:06:04Z","timestamp":1784196364078,"version":"3.55.0"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T00:00:00Z","timestamp":1769212800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T00:00:00Z","timestamp":1769212800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Urol Nephrol"],"DOI":"10.1007\/s11255-026-05029-z","type":"journal-article","created":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T09:42:51Z","timestamp":1769247771000},"page":"2909-2915","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The importance of targeted plus perilesional prostate biopsy in prostate cancer management (diagnosis and treatment)\u2014real world evidence of a tertiary centre"],"prefix":"10.1007","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2015-9636","authenticated-orcid":false,"given":"Samuel Silva","family":"Bastos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6391-3884","authenticated-orcid":false,"given":"V\u00edtor","family":"Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2730-9596","authenticated-orcid":false,"given":"Jorge","family":"Dias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1185-8577","authenticated-orcid":false,"given":"Lu\u00eds","family":"Xambre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-0436-2041","authenticated-orcid":false,"given":"Ana","family":"Saben\u00e7a","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-0564-6841","authenticated-orcid":false,"given":"Rui","family":"Maciel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-2555-8940","authenticated-orcid":false,"given":"Miguel","family":"Louren\u00e7o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1769-3651","authenticated-orcid":false,"given":"Jo\u00e3o","family":"Peralta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,1,24]]},"reference":[{"key":"5029_CR1","unstructured":"European Association of Urology (2025) EAU\u2013EANM\u2013ESTRO\u2013ESUR\u2013ISUP\u2013SIOG Guidelines on prostate cancer. Limited text update March 2025. urotoday.com; 2025"},{"issue":"6","key":"5029_CR2","doi-asserted-by":"publisher","first-page":"e101","DOI":"10.1016\/j.eururo.2021.08.010","volume":"80","author":"WG Brisbane","year":"2021","unstructured":"Brisbane WG et al (2021) Umbra and penumbra of prostate cancer: implications for MRI-targeted biopsy. Eur Urol 80(6):e101\u2013e103. https:\/\/doi.org\/10.1016\/j.eururo.2021.08.010","journal-title":"Eur Urol"},{"key":"5029_CR3","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1038\/s41391-022-00579-7","volume":"26","author":"JP Noujeim","year":"2023","unstructured":"Noujeim JP et al (2023) Optimizing multiparametric MRI targeted biopsy and detection of clinically significant prostate cancer: the role of perilesional sampling. Prostate Cancer Prostatic Dis 26:575\u2013582. https:\/\/doi.org\/10.1038\/s41391-022-00579-7","journal-title":"Prostate Cancer Prostatic Dis"},{"key":"5029_CR4","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/j.euros.2022.06.005","volume":"43","author":"MJ Hagens","year":"2022","unstructured":"Hagens MJ et al (2022) An MRI directed targeted plus perilesional biopsy approach for prostate cancer diagnosis: \u201cless is more.\u201d Eur Urol Open Sci 43:68\u201374. https:\/\/doi.org\/10.1016\/j.euros.2022.06.005","journal-title":"Eur Urol Open Sci"},{"key":"5029_CR5","doi-asserted-by":"publisher","DOI":"10.1038\/s41391-024-00884-2","author":"O Windisch","year":"2024","unstructured":"Windisch O (2024) Biopsy strategies in the era of mpMRI: a comprehensive review. Prostate Cancer Prostatic Dis. https:\/\/doi.org\/10.1038\/s41391-024-00884-2","journal-title":"Prostate Cancer Prostatic Dis"},{"issue":"6","key":"5029_CR6","doi-asserted-by":"publisher","first-page":"519","DOI":"10.3390\/medicina57060519","volume":"57","author":"I Andr\u00e1s","year":"2021","unstructured":"Andr\u00e1s I, Nyir\u00e1dy P, G\u00e9czi L et al (2021) Combined systematic and MRI\u2013US fusion prostate biopsy has the highest grading accuracy when compared to final pathology. Medicina (Kaunas) 57(6):519. https:\/\/doi.org\/10.3390\/medicina57060519","journal-title":"Medicina (Kaunas)"},{"key":"5029_CR7","doi-asserted-by":"publisher","first-page":"e860","DOI":"10.1016\/j.clgc.2019.05.006","volume":"17","author":"X Tu","year":"2019","unstructured":"Tu X et al (2019) Transperineal MRI-targeted biopsy may perform better than transrectal route in the detection of clinically significant prostate cancer: a systematic review and meta-analysis. Clin Genitourin Cancer 17:e860\u2013e868","journal-title":"Clin Genitourin Cancer"},{"key":"5029_CR8","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1186\/s12957-019-1573-0","volume":"17","author":"J Xiang","year":"2019","unstructured":"Xiang J et al (2019) Transperineal versus transrectal prostate biopsy in the diagnosis of prostate cancer: a systematic review and meta-analysis. World J Surg Oncol 17:31","journal-title":"World J Surg Oncol"},{"key":"5029_CR9","doi-asserted-by":"publisher","first-page":"1080","DOI":"10.1016\/j.euo.2024.01.019","volume":"7","author":"G Ploussard","year":"2024","unstructured":"Ploussard G et al (2024) Transperineal versus transrectal MRI-targeted biopsies for prostate cancer diagnosis: final results of the randomized PERFECT trial (CCAFU-PR1). Eur Urol Oncol 7:1080\u20131089","journal-title":"Eur Urol Oncol"},{"key":"5029_CR10","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1111\/bju.15628","volume":"129","author":"W Lam","year":"2022","unstructured":"Lam W et al (2022) Prostate cancer detection, tolerability and safety of transperineal prostate biopsy under local anaesthesia vs standard transrectal biopsy in biopsy-na\u00efve men: a randomized controlled study. BJU Int 129:9\u201316","journal-title":"BJU Int"},{"issue":"4","key":"5029_CR11","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1016\/j.prnil.2020.10.001","volume":"8","author":"JP Grummet","year":"2020","unstructured":"Grummet JP et al (2020) Transperineal versus transrectal prostate biopsy: an update in the era of targeted biopsy. Prostate Int 8(4):147\u2013152. https:\/\/doi.org\/10.1016\/j.prnil.2020.10.001","journal-title":"Prostate Int"},{"issue":"17","key":"5029_CR12","doi-asserted-by":"publisher","first-page":"1864","DOI":"10.3390\/diagnostics14171864","volume":"14","author":"S McGrath","year":"2024","unstructured":"McGrath S et al (2024) Comparative analysis of transperineal versus transrectal prostate biopsy for clinically significant cancer detection. Diagnostics 14(17):1864. https:\/\/doi.org\/10.3390\/diagnostics14171864","journal-title":"Diagnostics"},{"key":"5029_CR13","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1097\/JU.0000000000003788","volume":"211","author":"BM Mian","year":"2024","unstructured":"Mian BM et al (2024) Complications following transrectal and transperineal prostate biopsy: results of the ProBE-PC randomized clinical trial. J Urol 211:205\u2013214","journal-title":"J Urol"},{"key":"5029_CR14","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1097\/JU.0000000000002251","volume":"207","author":"D Castellani","year":"2022","unstructured":"Castellani D et al (2022) Infection rate after transperineal prostate biopsy with and without prophylactic antibiotics: a systematic review and meta-analysis. J Urol 207:25\u201333","journal-title":"J Urol"},{"key":"5029_CR15","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1111\/bju.15039","volume":"126","author":"B Berry","year":"2020","unstructured":"Berry B et al (2020) Comparison of complications after transrectal and transperineal prostate biopsy: a national population-based study. BJU Int 126:97\u2013103","journal-title":"BJU Int"},{"issue":"3","key":"5029_CR16","doi-asserted-by":"publisher","first-page":"415","DOI":"10.3390\/antibiotics11030415","volume":"11","author":"U Patel","year":"2022","unstructured":"Patel U et al (2022) Antibiotic prophylaxis in prostate biopsy: evolving strategies to minimize infection risk. Antibiotics 11(3):415. https:\/\/doi.org\/10.3390\/antibiotics11030415","journal-title":"Antibiotics"},{"key":"5029_CR17","doi-asserted-by":"publisher","DOI":"10.1016\/j.euf.2025.07.005","author":"R Jones","year":"2025","unstructured":"Jones R et al (2025) Infectious complications following transperineal prostate biopsy: a systematic review. Eur Urol Focus. https:\/\/doi.org\/10.1016\/j.euf.2025.07.005","journal-title":"Eur Urol Focus"},{"key":"5029_CR18","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2025.08.006","author":"E O\u2019Connor","year":"2025","unstructured":"O\u2019Connor E et al (2025) Modern transperineal biopsy techniques: redefining the standard of care in prostate cancer diagnosis. Urology. https:\/\/doi.org\/10.1016\/j.urology.2025.08.006","journal-title":"Urology"},{"key":"5029_CR19","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-024-05245-1","author":"A Lantz","year":"2024","unstructured":"Lantz A et al (2024) Comparing complications and cancer detection between transperineal and transrectal prostate biopsy approaches. World J Urol. https:\/\/doi.org\/10.1007\/s00345-024-05245-1","journal-title":"World J Urol"},{"issue":"3","key":"5029_CR20","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1016\/j.euo.2021.01.004","volume":"4","author":"S Loeb","year":"2021","unstructured":"Loeb S et al (2021) Infectious complications after prostate biopsy: safer transperineal approaches. Eur Urol Oncol 4(3):322\u2013329. https:\/\/doi.org\/10.1016\/j.euo.2021.01.004","journal-title":"Eur Urol Oncol"},{"issue":"1","key":"5029_CR21","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/j.euf.2023.01.016","volume":"9","author":"P Pepe","year":"2023","unstructured":"Pepe P et al (2023) Transperineal prostate biopsy under local anesthesia: evidence of reduced infectious complications. Eur Urol Focus 9(1):89\u201395. https:\/\/doi.org\/10.1016\/j.euf.2023.01.016","journal-title":"Eur Urol Focus"}],"container-title":["International Urology and Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11255-026-05029-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11255-026-05029-z","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11255-026-05029-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T09:19:18Z","timestamp":1784193558000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11255-026-05029-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,24]]},"references-count":21,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2026,8]]}},"alternative-id":["5029"],"URL":"https:\/\/doi.org\/10.1007\/s11255-026-05029-z","relation":{},"ISSN":["1573-2584"],"issn-type":[{"value":"1573-2584","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,24]]},"assertion":[{"value":"9 October 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 January 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 January 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}}]}}