{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T08:35:27Z","timestamp":1793003727656,"version":"4.5.0"},"reference-count":51,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T00:00:00Z","timestamp":1780358400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T00:00:00Z","timestamp":1780358400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Universidade De S\u00e3o Paulo","id":[{"id":"https:\/\/ror.org\/036rp1748","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Urol Nephrol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Robot-assisted radical prostatectomy (RARP) has increasingly replaced open radical prostatectomy (ORP) based on evidence suggesting improved perioperative outcomes and faster recovery. However, few randomized trials directly compare both techniques. This review compares perioperative, functional, and oncological outcomes of RARP versus ORP, integrating newly available high-impact studies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A thorough search of major databases was conducted from the inception of each database up to November 2025, adhering to PRISMA guidelines. Two reviewers independently screened studies in a three-step process\u2014titles, abstracts, and full texts. Only randomized controlled trials (RCTs) and prospective studies comparing RARP and ORP were included. All variables were entered into a spreadsheet for analysis and cross-checked. The primary endpoints assessed were perioperative complications, functional recovery (urinary continence and erectile function), and oncological outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 27 studies comprising 38,530 patients were included. Compared with ORP, RARP was associated with significantly reduced intraoperative blood loss (mean difference [MD]\u2009: \u2009\u2212\u2009576.78;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01), lower transfusion rates (Odds Ratio [OR] 0.27;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.0001), and shorter hospital stay (MD: \u2009\u2009\u2212\u20091.44\u00a0days;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.0001). RARP also demonstrated fewer postoperative complications (OR 0.59;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002). Regarding functional outcomes, RARP yielded superior urinary continence recovery at 3\u00a0months and improved erectile function recovery (OR 1.43). Additionally, RARP showed a lower biochemical recurrence rate at 24\u00a0months (OR 1.34), with no significant difference observed in short-term follow-up (&lt;\u200912\u00a0months).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>RARP offers advantages over ORP, particularly in reducing perioperative morbidity and enhancing functional recovery while maintaining comparable or superior oncological outcomes. However, further randomized controlled trials with extended follow-up are necessary to confirm these findings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Key messages<\/jats:title>\n                    <jats:p>\n                      <jats:list list-type=\"order\">\n                        <jats:list-item>\n                          <jats:p>RARP was associated with significantly reduced blood loss, lower transfusion requirements, and shorter hospitalization.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>Functional outcomes favored RARP, including superior recovery of urinary continence and higher rates of nerve-sparing preservation.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>Overall, the evidence supports RARP as a safe, effective, and clinically advantageous approach for localized prostate cancer.<\/jats:p>\n                        <\/jats:list-item>\n                      <\/jats:list>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s11255-026-05182-5","type":"journal-article","created":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T15:26:58Z","timestamp":1780414018000},"page":"4575-4593","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Comparative functional, perioperative and oncological outcomes of robot-assisted and open radical prostatectomy: a systematic review and meta-analysis"],"prefix":"10.1007","volume":"58","author":[{"given":"Caio Vinicius","family":"Suartz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mateus Silva Santos","family":"Costa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caio Felipe Araujo","family":"Matalani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo Ribeiro","family":"da Rocha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Pedro Cassemiro","family":"Micheleto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro Luis","family":"Furlam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrique Laurent","family":"Lepine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto Iglesias","family":"Lopes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thalita Bento","family":"Talizin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Bessa","family":"J\u00fanior","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walid","family":"Shahrour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walid","family":"Shabana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Axel S.","family":"Merseburger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo Oliveira","family":"Reis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maur\u00edcio Dener","family":"Cordeiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William Carlos","family":"Nahas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Toren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leopoldo Alves","family":"Ribeiro-Filho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume","family":"Ploussard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Fradet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Pouliot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,6,2]]},"reference":[{"issue":"3","key":"5182_CR1","first-page":"209","volume":"71","author":"H Sung","year":"2021","unstructured":"Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F (2021) Global cancer statistics 2020: GLOBO CAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 71(3):209\u2013249","journal-title":"CA Cancer J Clin"},{"issue":"1","key":"5182_CR2","first-page":"7","volume":"72","author":"RL Siegel","year":"2022","unstructured":"Siegel RL, Miller KD, Fuchs HE, Jemal A (2022) Cancer statis-tics, 2022. CA Cancer J Clin 72(1):7\u201333","journal-title":"CA Cancer J Clin"},{"key":"5182_CR3","doi-asserted-by":"publisher","first-page":"540","DOI":"10.5694\/mja12.11241","volume":"198","author":"SM Evans","year":"2013","unstructured":"Evans SM, Millar JL, Davis ID et al (2013) Patterns of care for men diagnosed with prostate cancer in Victoria from 2008 to 2011. Med J Aust 198:540\u2013545","journal-title":"Med J Aust"},{"issue":"15","key":"5182_CR4","doi-asserted-by":"publisher","first-page":"1415","DOI":"10.1056\/NEJMoa1606220","volume":"375","author":"FC Hamdy","year":"2016","unstructured":"Hamdy FC, Donovan JL, Lane JA, Mason M, Metcalfe C, Holding P, Davis M, Peters TJ, Turner EL, Martin RM, Oxley J, Robinson M, Staffurth J, Walsh E, Bollina P, Catto J, Doble A, Doherty A, Gillatt D, Kockelbergh R, Kynaston H, Paul A, Powell P, Prescott S, Rosario DJ, Rowe E, Neal DE, ProtecT Study Group (2016) 10-Year outcomes after monitoring, surgery, or radiotherapy for localized prostate cancer. N Engl J Med 375(15):1415\u20131424. https:\/\/doi.org\/10.1056\/NEJMoa1606220","journal-title":"N Engl J Med"},{"issue":"4","key":"5182_CR5","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1046\/j.1464-410x.2001.00115.x","volume":"87","author":"J Binder","year":"2001","unstructured":"Binder J, Kramer W (2001) Robotically-assisted laparoscopic radical prostatectomy. BJU Int 87(4):408\u2013410","journal-title":"BJU Int"},{"issue":"1","key":"5182_CR6","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1159\/000447495","volume":"98","author":"J Schifmann","year":"2017","unstructured":"Schifmann J, Larcher A, Sun M, Tian Z, Berdugo J, Leva I, Widmer H, Lattouf JB, Zorn K, Haese A et al (2017) Diferences in patient characteristics among men choosing open or robot-assisted radical prostatectomy in contemporary practice - analysis of surveillance, epidemiology, and end results database. Urol Int 98(1):40\u201348","journal-title":"Urol Int"},{"key":"5182_CR7","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/j.eururo.2006.06.017","volume":"51","author":"V Ficarra","year":"2007","unstructured":"Ficarra V, Cavalleri S, Novara G, Aragona M, Artibani W (2007) Evidence from robot-assisted laparoscopic radical prostatectomy: a systematic review. Eur Urol 51:45\u201355","journal-title":"Eur Urol"},{"issue":"4","key":"5182_CR8","doi-asserted-by":"publisher","first-page":"534","DOI":"10.1111\/j.1464-410X.2009.08419.x","volume":"104","author":"V Ficarra","year":"2009","unstructured":"Ficarra V, Novara G, Fracalanza S, D\u2019Elia C, Secco S, Iafrate M, Cavalleri S, Artibani W (2009) A prospective, non-randomized trial comparing robot-assisted laparoscopic and retropubic radical prostatectomy in one European institution. BJU Int 104(4):534\u2013539. https:\/\/doi.org\/10.1111\/j.1464-410X.2009.08419.x","journal-title":"BJU Int"},{"issue":"1","key":"5182_CR9","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1097\/JU.0000000000003967","volume":"212","author":"WC Nahas","year":"2024","unstructured":"Nahas WC, Rodrigues GJ, Rodrigues Gon\u00e7alves FA, Sawczyn GV, Barros GG, Cardili L, Guglielmetti GB, Fazoli AJC, Cordeiro MD, Cass\u00e3o VDA, Chade DC, Neves De Oliveira LC, Murta CB, Pontes J\u00fanior J, Trindade EM, Bastos DA, Sarkis AS, Mitre AI, Trinh QD, Coelho RF (2024) Perioperative, oncological, and functional outcomes between robot-assisted laparoscopic prostatectomy and open radical retropubic prostatectomy: a randomized clinical trial. J Urol 212(1):32\u201340. https:\/\/doi.org\/10.1097\/JU.0000000000003967","journal-title":"J Urol"},{"key":"5182_CR10","doi-asserted-by":"publisher","first-page":"2617","DOI":"10.1007\/s11701-023-01714-8","volume":"17","author":"J Wang","year":"2023","unstructured":"Wang J, Hu K, Wang Y et al (2023) Robot-assisted versus open radical prostatectomy: a systematic review and meta-analysis of prospective studies. J Robot Surg 17:2617\u20132631. https:\/\/doi.org\/10.1007\/s11701-023-01714-8","journal-title":"J Robot Surg"},{"key":"5182_CR11","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.g7647","volume":"350","author":"L Shamseer","year":"2015","unstructured":"Shamseer L, Moher D, Clarke M, Ghersi D, Liberati A, Petticrew M, Shekelle P, Stewart LA, PRISMA-P Group (2015) Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation. BMJ (Clinical research ed) 350:g7647. https:\/\/doi.org\/10.1136\/bmj.g7647","journal-title":"BMJ (Clinical research ed)"},{"issue":"3","key":"5182_CR12","first-page":"167","volume":"56","author":"JJ Riva","year":"2012","unstructured":"Riva JJ, Malik KM, Burnie SJ, Endicott AR, Busse JW (2012) What is your research question? An introduction to the PICOT format for clinicians. J Can Chiropr Assoc 56(3):167","journal-title":"J Can Chiropr Assoc"},{"key":"5182_CR13","doi-asserted-by":"publisher","DOI":"10.1186\/s13643-016-0384-4","volume":"5","author":"M Ouzzani","year":"2016","unstructured":"Ouzzani M, Hammady H, Fedorowicz Z, Elmagarmid A (2016) Rayyan \u2014 a web and mobile app for systematic reviews. Syst Rev 5:210. https:\/\/doi.org\/10.1186\/s13643-016-0384-4","journal-title":"Syst Rev"},{"issue":"29","key":"5182_CR14","doi-asserted-by":"publisher","first-page":"6072","DOI":"10.1002\/sim.3427","volume":"27","author":"JP Higgins","year":"2008","unstructured":"Higgins JP, White IR, Anzures-Cabrera J (2008) Meta-analysis of skewed data: combining results reported on log-transformed or raw scales. Stat Med 27(29):6072\u20136092. https:\/\/doi.org\/10.1002\/sim.3427","journal-title":"Stat Med"},{"issue":"2","key":"5182_CR15","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1097\/SLA.0b013e3181b13ca2","volume":"250","author":"PA Clavien","year":"2009","unstructured":"Clavien PA, Barkun J, De Oliveira ML, Vauthey JN, Dindo D, Schulick RD et al (2009) The Clavien-Dindo classification of surgical complications: five-year experience. Ann Surg 250(2):187\u2013196","journal-title":"Ann Surg"},{"key":"5182_CR16","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i4919","volume":"355","author":"JA Sterne","year":"2016","unstructured":"Sterne JA, Hern\u00c3\u00a1n MA, Reeves BC, Savovi\u00c4\u2021 J, Berkman ND, Viswanathan M et al (2016) ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions. BMJ 355:i4919. https:\/\/doi.org\/10.1136\/bmj.i4919","journal-title":"BMJ"},{"key":"5182_CR17","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.l4898","volume":"366","author":"JAC Sterne","year":"2019","unstructured":"Sterne JAC, Savovi\u0107 J, Page MJ, Elbers RG, Blencowe NS, Boutron I, Cates CJ, Cheng H-Y, Corbett MS, Eldridge SM, Hern\u00e1n MA, Hopewell S, Hr\u00f3bjartsson A, Junqueira DR, J\u00fcni P, Kirkham JJ, Lasserson T, Li T, McAleenan A, Reeves BC, Shepperd S, Shrier I, Stewart LA, Tilling K, White IR, Whiting PF, Higgins JPT (2019) RoB 2: A revised tool for assessing risk of bias in randomised trials. BMJ 366:l4898","journal-title":"BMJ"},{"key":"5182_CR18","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.b2535","volume":"339","author":"D Moher","year":"2009","unstructured":"Moher D, Liberati A, Tetzlaff J, Altman DG (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ 339:b2535","journal-title":"BMJ"},{"issue":"10049","key":"5182_CR19","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.1016\/S0140-6736(16)30592-X","volume":"388","author":"JW Yaxley","year":"2016","unstructured":"Yaxley JW, Coughlin GD, Chambers SK, Occhipinti S, Samara-tunga H, Zajdlewicz L, Dunglison N, Carter R, Williams S, Payton DJ et al (2016) Robot-assisted laparoscopic prostatectomy versus open radical retropubic prostatectomy: early outcomes from a randomised controlled phase 3 study. Lancet (London, England) 388(10049):1057\u20131066","journal-title":"Lancet (London, England)"},{"issue":"8","key":"5182_CR20","doi-asserted-by":"publisher","first-page":"1051","DOI":"10.1016\/S1470-2045(18)30357-7","volume":"19","author":"GD Coughlin","year":"2018","unstructured":"Coughlin GD, Yaxley JW, Chambers SK, Occhipinti S, Samara-tunga H, Zajdlewicz L, Teloken P, Dunglison N, Williams S, Lavin MF et al (2018) Robot-assisted laparoscopic prostatectomy versus open radical retropubic prostatectomy: 24 month outcomes from a randomised controlled study. Lancet Oncol 19(8):1051\u20131060","journal-title":"Lancet Oncol"},{"issue":"1","key":"5182_CR21","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.eururo.2010.10.026","volume":"59","author":"GB Di Pierro","year":"2011","unstructured":"Di Pierro GB, Baumeister P, Stucki P, Beatrice J, Danuser H, Mattei A (2011) A prospective trial comparing consecutive series of open retropubic and robot-assisted laparoscopic radical prostatectomy in a centre with a limited caseload. Eur Urol 59(1):1\u20136","journal-title":"Eur Urol"},{"issue":"3","key":"5182_CR22","doi-asserted-by":"publisher","first-page":"990","DOI":"10.1016\/j.juro.2009.11.017","volume":"183","author":"DA Barocas","year":"2010","unstructured":"Barocas DA, Salem S, Kordan Y, Herrell SD, Chang SS, Clark PE, Davis R, Baumgartner R, Phillips S, Cookson MS et al (2010) Robotic assisted laparoscopic prostatectomy versus radical retropubic prostatectomy for clinically localized prostate cancer: Comparison of short-term biochemical recurrence-free survival. J Urol 183(3):990\u2013996","journal-title":"J Urol"},{"key":"5182_CR23","doi-asserted-by":"publisher","first-page":"586","DOI":"10.23736\/S0393-2249.20.03830-8","volume":"72","author":"A Abdel Raheem","year":"2020","unstructured":"Abdel Raheem A, Hagras A, Ghaith A, Alenzi MJ, Elghiaty A, Gameel T et al (2020) Retzius-sparing robot-assisted radical prostatectomy versus open retropubic radical prostatectomy: A prospective comparative study with 19-month follow-up. Minerva Urol Nefrol 72:586\u2013594. https:\/\/doi.org\/10.23736\/S0393-2249.20.03830-8","journal-title":"Minerva Urol Nefrol"},{"issue":"2","key":"5182_CR24","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/j.eururo.2015.10.046","volume":"70","author":"P Capogrosso","year":"2016","unstructured":"Capogrosso P, Ventimiglia E, Serino A, Stabile A, Boeri L, Gandaglia G, Deh\u00f2 F, Briganti A, Montorsi F, Salonia A (2016) Orgasmic dysfunction after robot-assisted versus open radical prostatectomy. Eur Urol 70(2):223\u2013226. https:\/\/doi.org\/10.1016\/j.eururo.2015.10.046","journal-title":"Eur Urol"},{"key":"5182_CR25","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1111\/andr.12446","volume":"6","author":"P Capogrosso","year":"2018","unstructured":"Capogrosso P, Ventimiglia E, Cazzaniga W, Stabile A, Pederzoli F, Boeri L, Gandaglia G, Deh\u00f2 F, Briganti A, Montorsi F, Salonia A (2018) Long-term penile morphometric alterations in patients treated with robot-assisted versus open radical prostatectomy. Andrology 6:136\u2013141. https:\/\/doi.org\/10.1111\/andr.12446","journal-title":"Andrology"},{"issue":"4","key":"5182_CR26","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1111\/bju.13380","volume":"118","author":"WL Ong","year":"2016","unstructured":"Ong WL, Evans SM, Spelman T, Kearns PA, Murphy DG, Millar JL (2016) Comparison of oncological and health-related quality of life outcomes between open and robot-assisted radical prostatectomy for localised prostate cancer - fndings from the population-based Victorian prostate cancer registry. BJU Int 118(4):563\u2013569","journal-title":"BJU Int"},{"key":"5182_CR27","doi-asserted-by":"publisher","first-page":"936","DOI":"10.1111\/bju.12258","volume":"112","author":"I Geraerts","year":"2013","unstructured":"Geraerts I, Van Poppel H, Devoogdt N, Van Cleynenbreugel B, Joniau S, Van Kampen M (2013) Functional outcomes after ORP and RARP. BJU Int 112:936\u2013943. https:\/\/doi.org\/10.1111\/bju.12258","journal-title":"BJU Int"},{"issue":"6","key":"5182_CR28","doi-asserted-by":"publisher","first-page":"777","DOI":"10.1093\/bja\/aeq247","volume":"105","author":"JY Hong","year":"2010","unstructured":"Hong JY, Kim JY, Choi YD, Rha KH, Yoon SJ, Kil HK (2010) Incidence of venous gas embolism during robotic-assisted laparoscopic radical prostatectomy is lower than that during radical retropubic prostatectomy. Br J Anaesth 105(6):777\u2013781. https:\/\/doi.org\/10.1093\/bja\/aeq247","journal-title":"Br J Anaesth"},{"issue":"3","key":"5182_CR29","doi-asserted-by":"publisher","first-page":"378","DOI":"10.1111\/j.1464-410X.2009.09158.x","volume":"106","author":"N Doumerc","year":"2010","unstructured":"Doumerc N, Yuen C, Savdie R, Rahman MB, Rasiah KK, Pe Benito R, Delprado W, Matthews J, Haynes AM, Stricker PD (2010) Should experienced open prostatic surgeons convert to robotic surgery? The real learning curve for one surgeon over 3 years. BJU Int 106(3):378\u2013384","journal-title":"BJU Int"},{"issue":"1-2","key":"5182_CR30","doi-asserted-by":"publisher","first-page":"e68","DOI":"10.5489\/cuaj.480","volume":"8","author":"BJ Davison","year":"2014","unstructured":"Davison BJ, Matthew A, Gardner AM (2014) Prospective comparison of the impact of robotic-assisted laparoscopic radical prostatectomy versus open radical prostatectomy on health-related quality of life and decision regret. Can Urol Assoc J 8(1\u20132):e68-72. https:\/\/doi.org\/10.5489\/cuaj.480","journal-title":"Can Urol Assoc J"},{"issue":"7","key":"5182_CR31","doi-asserted-by":"publisher","first-page":"991","DOI":"10.1111\/j.1464-410X.2009.08532.x","volume":"104","author":"B Rocco","year":"2009","unstructured":"Rocco B, Matei DV, Melegari S, Ospina JC, Mazzoleni F, Errico G, Mastropasqua M, Santoro L, Detti S, de Cobelli O (2009) Robotic vs open prostatectomy in a laparoscopically naive center: a matched-pair analysis. BJU Int 104(7):991\u2013995","journal-title":"BJU Int"},{"issue":"5","key":"5182_CR32","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1016\/j.acuroe.2021.12.001","volume":"46","author":"\u00c1 Garc\u00eda Cort\u00e9s","year":"2022","unstructured":"Garc\u00eda Cort\u00e9s \u00c1, Colomb\u00e1sVives J, Guti\u00e9rrez Casta\u00f1\u00e9 C, Chiva San Rom\u00e1n S, Dom\u00e9nechL\u00f3pez P, AncizuMarckert FJ, Hevia Su\u00e1rez M, Merino Narro I, VelisCampillo JM, Guill\u00e9nGrima F, Torres Roca M, Diez-Caballero y Alonso F, Rosell Costa D, VillacampaAub\u00e1 F, de Fata Chill\u00f3n FR, Andr\u00e9s Boville G, BarbasBernardos G, Mi\u00f1anaL\u00f3pez B, Robles Garc\u00eda JE, PascualPi\u00e9drola JI (2022) Comparison of surgical approaches to radical prostatectomy in our series beyond oncological and functional outcomes. Actas Urol\u00f3gicas Espa\u00f1olas (English Edition) 46(5):275\u2013284. https:\/\/doi.org\/10.1016\/j.acuroe.2021.12.001","journal-title":"Actas Urol\u00f3gicas Espa\u00f1olas (English Edition)"},{"issue":"2","key":"5182_CR33","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1016\/j.eururo.2015.02.029","volume":"68","author":"E Haglind","year":"2015","unstructured":"Haglind E, Carlsson S, Stranne J, Wallerstedt A, Wilder\u00e4ng U, Thorsteinsdottir T, Lagerkvist M, Damber JE, Bjartell A, Hugosson J, Wiklund P, Steineck G, LAPPRO steering committee (2015) Urinary incontinence and erectile dysfunction after robotic versus open radical prostatectomy: a prospective, controlled, nonrandomised trial. Eur Urol 68(2):216\u2013225. https:\/\/doi.org\/10.1016\/j.eururo.2015.02.029","journal-title":"Eur Urol"},{"issue":"1","key":"5182_CR34","doi-asserted-by":"publisher","first-page":"15","DOI":"10.4111\/kju.2013.54.1.15","volume":"54","author":"MS Choo","year":"2013","unstructured":"Choo MS, Choi WS, Cho SY, Ku JH, Kim HH, Kwak C (2013) Impact of prostate volume on oncological and functional outcomes after radical prostatectomy: robot-assisted laparoscopic versus open retropubic. Korean J Urol 54(1):15\u201321. https:\/\/doi.org\/10.4111\/kju.2013.54.1.15","journal-title":"Korean J Urol"},{"key":"5182_CR35","doi-asserted-by":"publisher","first-page":"1031","DOI":"10.1111\/bju.14760","volume":"123","author":"A Haese","year":"2019","unstructured":"Haese A, Knipper S, Isbarn H, Heinzer H, Tilki D, Salomon G, Michl U, Steuber T, Bud\u00e4us L, Maurer T, Tennstedt P, Huland H, Graefen M (2019) A comparative study of robot-assisted and open radical prostatectomy in 10 790 men treated by highly trained surgeons for both procedures. BJU Int 123:1031\u20131040. https:\/\/doi.org\/10.1111\/bju.14760","journal-title":"BJU Int"},{"issue":"1","key":"5182_CR36","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1097\/JU.0000000000002176","volume":"207","author":"P Chang","year":"2022","unstructured":"Chang P, Wagner AA, Regan MM, Smith JA, Saigal CS, Litwin MS et al (2022) Prospective multicenter comparison of open and robotic radical prostatectomy: the PROST-QA\/RP2 consortium. J Urol 207(1):127\u2013136. https:\/\/doi.org\/10.1097\/JU.0000000000002176","journal-title":"J Urol"},{"key":"5182_CR37","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1007\/s11701-008-0111-9","volume":"2","author":"WS Ham","year":"2008","unstructured":"Ham WS, Park SY, Kim WT et al (2008) Open versus robotic radical prostatectomy: a prospective analysis based on a single surgeon\u2019s experience. J Robot Surg 2:235\u2013241. https:\/\/doi.org\/10.1007\/s11701-008-0111-9","journal-title":"J Robot Surg"},{"issue":"1","key":"5182_CR38","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1080\/21681805.2018.1556729","volume":"53","author":"A Wallerstedt Lantz","year":"2019","unstructured":"Wallerstedt Lantz A, Stranne J, Tyritzis SI, Bock D, Wallin D, Nilsson H, Carlsson S, Thorsteinsdottir T, Gustafsson O, Hugosson J, Bjartell A, Wiklund P, Steineck G, Haglind E (2019) 90-Day readmission after radical prostatectomy\u2014a prospective comparison between robot-assisted and open surgery. Scand J Urol 53(1):26\u201333. https:\/\/doi.org\/10.1080\/21681805.2018.1556729","journal-title":"Scand J Urol"},{"issue":"4","key":"5182_CR39","doi-asserted-by":"publisher","first-page":"618","DOI":"10.1016\/j.eururo.2017.08.015","volume":"73","author":"P Sooriakumaran","year":"2018","unstructured":"Sooriakumaran P, Pini G, Nyberg T, Derogar M, Carlsson S, Stranne J, Bjartell A, Hugosson J, Steineck G, Wiklund PN (2018) Erectile function and oncologic outcomes following open retropubic and robot-assisted radical prostatectomy: results from the LAParoscopic Prostatectomy Robot Open Trial. Eur Urol 73(4):618\u2013627. https:\/\/doi.org\/10.1016\/j.eururo.2017.08.015","journal-title":"Eur Urol"},{"issue":"5","key":"5182_CR40","doi-asserted-by":"publisher","first-page":"650","DOI":"10.1016\/j.eururo.2021.07.025","volume":"80","author":"A Lantz","year":"2021","unstructured":"Lantz A, Bock D, Akre O, Angenete E, Bjartell A, Carlsson S, Modig KK, Nyberg M, Kollberg KS, Steineck G, Stranne J, Wiklund P, Haglind E (2021) Functional and oncological outcomes after open versus robot-assisted laparoscopic radical prostatectomy for localised prostate cancer: 8-Year follow-up. Eur Urol 80(5):650\u2013660. https:\/\/doi.org\/10.1016\/j.eururo.2021.07.025","journal-title":"Eur Urol"},{"issue":"6","key":"5182_CR41","doi-asserted-by":"publisher","first-page":"2445","DOI":"10.3892\/or.2013.2365","volume":"29","author":"GM Ludovico","year":"2013","unstructured":"Ludovico GM, Dachille G, Pagliarulo G, D\u2019Elia C, Mondaini N, Gacci M, Detti B, Malossini G, Bartoletti R, Cai T (2013) Bilateral nerve sparing robotic-assisted radical prostatectomy is associated with faster continence recovery but not with erectile function recovery compared with retropubic open prostatectomy: The need for accurate selection of patients. Oncol Rep 29(6):2445\u20132450. https:\/\/doi.org\/10.3892\/or.2013.2365","journal-title":"Oncol Rep"},{"key":"5182_CR42","doi-asserted-by":"publisher","first-page":"3239","DOI":"10.1007\/s00345-021-03662-0","volume":"39","author":"A Hagman","year":"2021","unstructured":"Hagman A, Lantz A, Carlsson S et al (2021) Urinary continence recovery and oncological outcomes after surgery for prostate cancer analysed by risk category: Results from the LAParoscopic prostatectomy robot and open trial. World J Urol 39:3239\u20133249","journal-title":"World J Urol"},{"issue":"5","key":"5182_CR43","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1016\/j.euo.2018.04.012","volume":"1","author":"M Nyberg","year":"2018","unstructured":"Nyberg M, Hugosson J, Wiklund P, Sjoberg D, Wilder\u00e4ng U, Carlsson SV, Carlsson S, Stranne J, Steineck G, Haglind E, Bjartell A, LAPPRO group (2018) Functional and oncologic outcomes between open and robotic radical prostatectomy at 24-month follow-up in the Swedish LAPPRO trial. Eur Urol Oncol 1(5):353\u2013360. https:\/\/doi.org\/10.1016\/j.euo.2018.04.012","journal-title":"Eur Urol Oncol"},{"issue":"6","key":"5182_CR44","doi-asserted-by":"publisher","first-page":"845","DOI":"10.1111\/bju.14062","volume":"121","author":"D Ilic","year":"2018","unstructured":"Ilic D, Evans SM, Allan CA, Jung JH, Murphy D, Frydenberg M (2018) Laparoscopic and robot-assisted vs open radical prostatectomy for the treatment of localized prostate cancer: a Cochrane systematic review. BJU Int 121(6):845\u2013853","journal-title":"BJU Int"},{"key":"5182_CR45","first-page":"272","volume":"24","author":"Y Du","year":"2018","unstructured":"Du Y, Long Q, Guan B, Mu L, Tian J, Jiang Y, Bai X, Wu D (2018) Robot-assisted radical prostatectomy is more benefcial for prostate cancer patients: a system review and meta-analysis. Med Sci Monit Int Med J Exp Clin Res 24:272\u2013287","journal-title":"Med Sci Monit Int Med J Exp Clin Res"},{"issue":"22","key":"5182_CR46","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000015770","volume":"98","author":"L Cao","year":"2019","unstructured":"Cao L, Yang Z, Qi L, Chen M (2019) Robot-assisted and laparoscopic vs open radical prostatectomy in clinically localized prostate cancer: perioperative, functional, and oncological outcomes\u2014a systematic review and meta-analysis. Medicine 98(22):e1577","journal-title":"Medicine"},{"key":"5182_CR47","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2024.04.008","author":"G Basile","year":"2024","unstructured":"Basile G, Gallioli A, Diana P, Gallagher A, Larcher A, Graefen M, Harke N, Traxer O, Tilki D, Van Der Poel H, Emiliani E, Angerri O, Wagner C, Montorsi F, Wiklund P, Somani B, Buffi N, Mottrie A, Liatsikos E, Breda A (2024) Current standards for training in robot-assisted surgery and endourology: a systematic review. Eur Urol. https:\/\/doi.org\/10.1016\/j.eururo.2024.04.008","journal-title":"Eur Urol"},{"key":"5182_CR48","doi-asserted-by":"crossref","unstructured":"Zattoni F, Artibani W, Patel V, Montorsi F, Porpiglia F, Hampton LJ, Rocco B, Dasgupta P, Hemal AK, Mottrie A et al (2019) Technical innovations to optimize continence recovery after robotic assisted","DOI":"10.23736\/S0393-2249.19.03395-2"},{"issue":"4","key":"5182_CR49","doi-asserted-by":"publisher","first-page":"1392","DOI":"10.1016\/j.juro.2011.11.089","volume":"187","author":"HY Yu","year":"2012","unstructured":"Yu HY, Hevelone ND, Lipsitz SR, Kowalczyk KJ, Hu JC (2012) Use, costs and comparative effectiveness of robotic assisted, laparoscopic and open urological surgery. J Urol 187(4):1392\u20131398","journal-title":"J Urol"},{"key":"5182_CR50","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1186\/1471-2490-14-28","volume":"14","author":"M Froehner","year":"2014","unstructured":"Froehner M, Kellner AE, Koch R, Baretton GB, Hakenberg OW, Wirth MP (2014) A combined index to classify prognostic comorbidity in candidates for radical prostatectomy. BMC Urol 14:28","journal-title":"BMC Urol"},{"issue":"6","key":"5182_CR51","doi-asserted-by":"publisher","first-page":"1859","DOI":"10.1016\/j.euf.2022.06.006","volume":"8","author":"TBC Moretti","year":"2022","unstructured":"Moretti TBC, Reis LO (2022) The \u201cNatural History\u201d of evidence on radical prostatectomy: What have 20 years of robots given us? Eur Urol Focus 8(6):1859\u20131860. https:\/\/doi.org\/10.1016\/j.euf.2022.06.006","journal-title":"Eur Urol Focus"}],"container-title":["International Urology and Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11255-026-05182-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11255-026-05182-5","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11255-026-05182-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T08:05:13Z","timestamp":1793001913000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11255-026-05182-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,2]]},"references-count":51,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2026,11]]}},"alternative-id":["5182"],"URL":"https:\/\/doi.org\/10.1007\/s11255-026-05182-5","relation":{},"ISSN":["1573-2584"],"issn-type":[{"value":"1573-2584","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,2]]},"assertion":[{"value":"5 February 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 April 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 June 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare that there are no competing interests.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}}]}}