{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T04:21:36Z","timestamp":1790310096548,"version":"4.1.0"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T00:00:00Z","timestamp":1784764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T00:00:00Z","timestamp":1784764800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Johann Wolfgang Goethe-Universit\u00e4t, Frankfurt am Main"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Urol Nephrol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Prolonged time to nephrectomy (TTN) has been associated with adverse oncologic outcomes. We evaluated temporal trends and sociodemographic determinants of prolonged TTN in surgically treated patients with localized renal cell carcinoma (RCC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients with T1\u20132 N0 M0 RCC treated with partial (PN) or radical nephrectomy (RN) were identified within the Surveillance, Epidemiology and End Results (SEER) database (2004\u20132022) and stratified according to TTN\u2009\u2264\u20093 vs.\u2009&gt;\u20093 months. Multivariable logistic regression models identified independent and combined sociodemographic determinants of TTN\u2009&gt;\u20093 months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 54,365 patients, TTN\u2009&gt;\u20093 months was recorded in 28% of PN and 18% of RN patients. The proportion of TTN\u2009&gt;\u20093 months increased over time in both PN (from 19 to 36%, p\u2009&lt;\u20090.001) and RN (from 11 to 31%, p\u2009&lt;\u20090.001). Higher rates of TTN\u2009&gt;\u20093 months were recorded in non-Caucasian vs. Caucasian patients (PN: 33% vs 25%, OR 1.49; RN: 24% vs 15%, OR 1.74), unmarried vs. married individuals (PN: 33% vs. 25%, OR 1.43; RN: 22% vs. 15%, OR 1.58), and males vs. females (PN: 28% vs 27%, OR 1.18; RN: 18% vs 18%, OR 1.20; all p\u2009&lt;\u20090.001). Combined assessment revealed highest rates in non-Caucasian unmarried males at PN (40%, OR 2.70, p\u2009&lt;\u20090.001) and RN (28%, OR 3.09, p\u2009&lt;\u20090.001) compared to lowest rates in Caucasian married females (PN: 21%; RN: 12%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>TTN\u2009&gt;\u20093 months proportion increased over time in localized RCC. In PN and RN, non-Caucasian unmarried males are at highest risk of TTN\u2009&gt;\u20093 months. Therefore, specific focus on these highest risk individuals may be warranted within strategies aimed at minimizing TTN.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s11255-026-05303-0","type":"journal-article","created":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T17:29:39Z","timestamp":1784827779000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Temporal trends and sociodemographic determinants of time to nephrectomy in localized renal cell cancer"],"prefix":"10.1007","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-5715-9965","authenticated-orcid":false,"given":"Maximilian","family":"Filzmayer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Petix","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo","family":"Quarta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filippo","family":"Orlandi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordan A.","family":"Goyal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Carmignani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Briganti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salvatore","family":"Micali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahrokh F.","family":"Shariat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mike","family":"Wenzel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miriam I.","family":"Traumann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara","family":"Humke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fred","family":"Saad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix K.-H.","family":"Chun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre I.","family":"Karakiewicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,23]]},"reference":[{"key":"5303_CR1","doi-asserted-by":"publisher","first-page":"779","DOI":"10.1097\/SLA.0b013e318211cc0f","volume":"253","author":"KY Bilimoria","year":"2011","unstructured":"Bilimoria KY, Ko CY, Tomlinson JS et al (2011) Wait times for cancer surgery in the United States: trends and predictors of delays. 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