{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:19:35Z","timestamp":1792783175481,"version":"4.5.0"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T00:00:00Z","timestamp":1785110400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T00:00:00Z","timestamp":1785110400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"Moscow Center for Innovative Technologies in Healthcare","id":[{"id":"https:\/\/ror.org\/02y1rjh68","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Urol Nephrol"],"DOI":"10.1007\/s11255-026-05305-y","type":"journal-article","created":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T08:37:46Z","timestamp":1785141466000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["NephroAge: quantifying accelerated aging in hemodialysis patients through vintage-calibrated mortality risk"],"prefix":"10.1007","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5405-7887","authenticated-orcid":false,"given":"Alexey","family":"Zulkarnaev","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3625-1824","authenticated-orcid":false,"given":"Ekaterina","family":"Parshina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5473-2272","authenticated-orcid":false,"given":"Marina","family":"Minina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5731-3310","authenticated-orcid":false,"given":"Ilya","family":"Dmitriev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0881-0599","authenticated-orcid":false,"given":"Vadim","family":"Stepanov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,27]]},"reference":[{"key":"5305_CR1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-83547-5","volume":"14","author":"Y Otaki","year":"2024","unstructured":"Otaki Y, Watanabe T, Konta T et al (2024) Macrocytic anemia, kidney dysfunction, and mortality in general population: Japan specific health checkup study. Sci Rep 14:32005. https:\/\/doi.org\/10.1038\/s41598-024-83547-5","journal-title":"Sci Rep"},{"key":"5305_CR2","doi-asserted-by":"publisher","first-page":"98","DOI":"10.2215\/CJN.12941213","volume":"10","author":"F Tentori","year":"2015","unstructured":"Tentori F, Wang M, Bieber BA et al (2015) Recent changes in therapeutic approaches and association with outcomes among patients with secondary hyperparathyroidism on chronic hemodialysis: the DOPPS study. Clin J Am Soc Nephrol 10:98\u2013109. https:\/\/doi.org\/10.2215\/CJN.12941213","journal-title":"Clin J Am Soc Nephrol"},{"key":"5305_CR3","doi-asserted-by":"publisher","first-page":"1096","DOI":"10.1038\/ki.2013.147","volume":"84","author":"T Alp Ikizler","year":"2013","unstructured":"Alp Ikizler T, Cano NJ, Franch H et al (2013) Prevention and treatment of protein energy wasting in chronic kidney disease patients: a consensus statement by the International Society of Renal Nutrition and Metabolism. Kidney Int 84:1096\u20131107. https:\/\/doi.org\/10.1038\/ki.2013.147","journal-title":"Kidney Int"},{"key":"5305_CR4","doi-asserted-by":"publisher","first-page":"345","DOI":"10.3390\/toxins17070345","volume":"17","author":"\u00c1G Peth\u0151","year":"2025","unstructured":"Peth\u0151 \u00c1G, F\u00fcl\u00f6p T, Orosz P et al (2025) Increased cardiovascular mortality in hemodialysis: the role of chronic inflammation, complement activation, and non-biocompatibility. Toxins (Basel) 17:345. https:\/\/doi.org\/10.3390\/toxins17070345","journal-title":"Toxins (Basel)"},{"key":"5305_CR5","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1111\/sdi.12694","volume":"31","author":"S Ahmadmehrabi","year":"2018","unstructured":"Ahmadmehrabi S, Wilson Tang WH (2018) Hemodialysis-induced cardiovascular disease. Semin Dial 31:258\u2013267. https:\/\/doi.org\/10.1111\/sdi.12694","journal-title":"Semin Dial"},{"key":"5305_CR6","doi-asserted-by":"publisher","first-page":"1813","DOI":"10.1007\/s11255-011-0085-9","volume":"44","author":"M Rattanasompattikul","year":"2012","unstructured":"Rattanasompattikul M, Feroze U, Molnar MZ et al (2012) Charlson comorbidity score is a strong predictor of mortality in hemodialysis patients. Int Urol Nephrol 44:1813\u20131823. https:\/\/doi.org\/10.1007\/s11255-011-0085-9","journal-title":"Int Urol Nephrol"},{"key":"5305_CR7","doi-asserted-by":"publisher","DOI":"10.1186\/s12877-020-01697-3","volume":"20","author":"R Artzi-Medvedik","year":"2020","unstructured":"Artzi-Medvedik R, Kob R, Fabbietti P et al (2020) Impaired kidney function is associated with lower quality of life among community-dwelling older adults: the screening for CKD among older people across Europe (SCOPE) study. BMC Geriatr 20:340. https:\/\/doi.org\/10.1186\/s12877-020-01697-3","journal-title":"BMC Geriatr"},{"key":"5305_CR8","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1089\/dis.2006.9.224","volume":"9","author":"JJ Sands","year":"2006","unstructured":"Sands JJ, Etheredge GD, Shankar A et al (2006) Predicting hospitalization and mortality in end-stage renal disease (ESRD) patients using an index of coexisting disease (ICED)\u2013based risk stratification model. Dis Manag 9:224\u2013235. https:\/\/doi.org\/10.1089\/dis.2006.9.224","journal-title":"Dis Manag"},{"key":"5305_CR9","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1016\/S0272-6386(03)00415-3","volume":"42","author":"BR Hemmelgarn","year":"2003","unstructured":"Hemmelgarn BR, Manns BJ, Quan H, Ghali WA (2003) Adapting the charlson comorbidity index for use in patients with ESRD. Am J Kidney Dis 42:125\u2013132. https:\/\/doi.org\/10.1016\/S0272-6386(03)00415-3","journal-title":"Am J Kidney Dis"},{"key":"5305_CR10","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/S0272-6386(12)80245-9","volume":"17","author":"LF Wright","year":"1991","unstructured":"Wright LF (1991) Survival in patients with end-stage renal disease. Am J Kidney Dis 17:25\u201328. https:\/\/doi.org\/10.1016\/S0272-6386(12)80245-9","journal-title":"Am J Kidney Dis"},{"key":"5305_CR11","doi-asserted-by":"publisher","first-page":"996","DOI":"10.1038\/ki.2014.419","volume":"87","author":"J Floege","year":"2015","unstructured":"Floege J, Gillespie IA, Kronenberg F et al (2015) Development and validation of a predictive mortality risk score from a European hemodialysis cohort. Kidney Int 87:996\u20131008. https:\/\/doi.org\/10.1038\/ki.2014.419","journal-title":"Kidney Int"},{"key":"5305_CR12","unstructured":"Russia. Total population data. In: Human Mortality Database. https:\/\/www.mortality.org\/Country\/Country?cntr=RUS. Accessed 10 Feb 2026"},{"key":"5305_CR13","unstructured":"Zulkarnaev A NephroAge Calculator with 3D Visualization. In: NephroAge. https:\/\/azulkarnaev.shinyapps.io\/NephroAge\/. Accessed 10 Feb 2026"},{"key":"5305_CR14","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1016\/j.ejvs.2018.02.001","volume":"55","author":"J Schmidli","year":"2018","unstructured":"Schmidli J, Widmer MK, Basile C et al (2018) Editor\u2019s choice - vascular access: 2018 clinical practice guidelines of the European society for vascular surgery (ESVS). Eur J Vasc Endovasc Surg 55:757\u2013818. https:\/\/doi.org\/10.1016\/j.ejvs.2018.02.001","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"5305_CR15","doi-asserted-by":"publisher","first-page":"S1","DOI":"10.1053\/j.ajkd.2019.12.001","volume":"75","author":"CE Lok","year":"2020","unstructured":"Lok CE, Huber TS, Lee T et al (2020) KDOQI clinical practice guideline for vascular access: 2019 update. Am J Kidney Dis 75:S1\u2013S164. https:\/\/doi.org\/10.1053\/j.ajkd.2019.12.001","journal-title":"Am J Kidney Dis"},{"key":"5305_CR16","unstructured":"Annual Reports 2023. In: European Renal Association. https:\/\/www.era-online.org\/research-education\/era-registry\/annual-reports\/. Accessed 11 Jan 2026"}],"container-title":["International Urology and Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11255-026-05305-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11255-026-05305-y","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11255-026-05305-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T22:01:58Z","timestamp":1790546518000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11255-026-05305-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,27]]},"references-count":16,"alternative-id":["5305"],"URL":"https:\/\/doi.org\/10.1007\/s11255-026-05305-y","relation":{},"ISSN":["1573-2584"],"issn-type":[{"value":"1573-2584","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,27]]},"assertion":[{"value":"16 May 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 July 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 July 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 September 2026","order":5,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Update","order":6,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This article was originally published under the subscription model but it is now published under an Open Access license.","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors have no conflicts of interest to declare.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}}]}}