{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T06:00:32Z","timestamp":1769148032396,"version":"3.49.0"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2021,12,2]],"date-time":"2021-12-02T00:00:00Z","timestamp":1638403200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,12,2]],"date-time":"2021-12-02T00:00:00Z","timestamp":1638403200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100003407","name":"Ministero dell\u2019Istruzione, dell\u2019Universit\u00e0 e della Ricerca","doi-asserted-by":"publisher","award":["MUR, DOR1923977\/19"],"award-info":[{"award-number":["MUR, DOR1923977\/19"]}],"id":[{"id":"10.13039\/501100003407","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Vet Res Commun"],"published-print":{"date-parts":[[2022,6]]},"DOI":"10.1007\/s11259-021-09860-w","type":"journal-article","created":{"date-parts":[[2021,12,2]],"date-time":"2021-12-02T16:04:41Z","timestamp":1638461081000},"page":"597-602","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["A case report of a rapid development of fetal anasarca in a canine pregnancy at term"],"prefix":"10.1007","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3582-2963","authenticated-orcid":false,"given":"Giulia","family":"Siena","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michela","family":"Corr\u00f2","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"Zanardello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Greta","family":"Foiani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Romagnoli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lluis","family":"Ferr\u00e9-Dolcet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiara","family":"Milani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,12,2]]},"reference":[{"issue":"6","key":"9860_CR1","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1016\/S0146-0005(05)80056-4","volume":"19","author":"SD Barron","year":"1995","unstructured":"Barron SD, Pass RF (1995) Infectious causes of Hydrops Fetalis. Sem Perinatol 19(6):493\u2013501","journal-title":"Sem Perinatol"},{"issue":"5","key":"9860_CR2","doi-asserted-by":"publisher","first-page":"1082","DOI":"10.1002\/ajmg.a.36988","volume":"167","author":"C Bellini","year":"2015","unstructured":"Bellini C, Donarini G, Paladini D, Calevo MG, Bellini T, Ramenghi LA, Hennekam RC (2015) Etiology of non-immune Hydrops Fetalis: an update. Am J Med Genet Part A 167(5):1082\u20131088","journal-title":"Am J Med Genet Part A"},{"issue":"4","key":"9860_CR3","doi-asserted-by":"publisher","first-page":"1007","DOI":"10.1016\/S0095-5108(05)70061-0","volume":"27","author":"R Bukowski","year":"2000","unstructured":"Bukowski R, Saade GR (2000) Hydrops Fetalis. Clin Perinatol 27(4):1007\u20131031","journal-title":"Clin Perinatol"},{"issue":"21","key":"9860_CR4","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1136\/vr.99.21.424","volume":"99","author":"M Chew-Lim","year":"1976","unstructured":"Chew-Lim M (1976) Hydrocephalus and anasarca in a Pekingese litter. Vet Rec 99(21):424\u2013425","journal-title":"Vet Rec"},{"issue":"2","key":"9860_CR5","first-page":"251","volume":"35","author":"M Cunto","year":"2015","unstructured":"Cunto M, Zambelli D, Castagnetti C, Linta N, Bini C (2015) Diagnosis and treatment of Foetal anasarca in two English bulldog puppies. Pak Vet J 35(2):251\u2013253","journal-title":"Pak Vet J"},{"key":"9860_CR6","first-page":"655","volume-title":"Veterinary reproduction and obstetrics","author":"G England","year":"2009","unstructured":"England G (2009) Infertility and subfertility in the bitch and queen. In: Veterinary reproduction and obstetrics, 9th edn. Saunders Elsevier, Philadelphia, pp 655\u2013657","edition":"9"},{"issue":"1","key":"9860_CR7","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1177\/8756479310392351","volume":"27","author":"K Having","year":"2011","unstructured":"Having K, Bullock S (2011) Fetal Anasarca. J Diagn Med Sonogr 27(1):19\u201325","journal-title":"J Diagn Med Sonogr"},{"key":"9860_CR8","doi-asserted-by":"publisher","first-page":"51","DOI":"10.2460\/javma.239.1.51","volume":"239","author":"HG Heng","year":"2011","unstructured":"Heng HG, Randall E, Williams K, Johnson C (2011) What is your diagnosis? Hydrops fetalis. J Am Vet Med Ass 239:51\u201352","journal-title":"J Am Vet Med Ass"},{"issue":"1","key":"9860_CR9","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1111\/j.1748-5827.2004.tb00187.x","volume":"45","author":"BJ Hopper","year":"2004","unstructured":"Hopper BJ, Richardson JL, Lester NV (2004) Spontaneous antenatal resolution or canine Hydrops Fetalis diagnosed by ultrasound. J Small Anim Pract 45(1):2\u20138","journal-title":"J Small Anim Pract"},{"issue":"4","key":"9860_CR10","doi-asserted-by":"publisher","first-page":"681","DOI":"10.1292\/jvms.55.681","volume":"55","author":"M Kaneko","year":"1993","unstructured":"Kaneko M, Nakayama H, Igarashi N, Hirose H (1993) Relationship between the number of fetuses and the blood constituents of beagles in late pregnancy. J Vet Med Sci 55(4):681\u2013682","journal-title":"J Vet Med Sci"},{"key":"9860_CR11","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.theriogenology.2017.04.023","volume":"97","author":"S Klainbart","year":"2017","unstructured":"Klainbart S, Slon A, Kelmer E, Bdolah-Abram T, Raz T, Segev G, Aroch I, Tal S (2017) Global hemostasis in healthy bitches during pregnancy and at different estrous cycle stages: evaluation of routine hemostatic tests and Thromboelastometry. Theriogenology 97:57\u201366","journal-title":"Theriogenology"},{"key":"9860_CR12","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1016\/j.cvsm.2012.01.015","volume":"42","author":"CG Lamm","year":"2012","unstructured":"Lamm CG, Njaa BL (2012) Clinical approach to abortion, stillbirth, and neonatal death in dogs and cats. Vet Clin Small Anim 42:501\u2013513","journal-title":"Vet Clin Small Anim"},{"issue":"4","key":"9860_CR13","doi-asserted-by":"publisher","first-page":"R1045","DOI":"10.1152\/ajpregu.2001.280.4.R1045","volume":"280","author":"ER Lumbers","year":"2001","unstructured":"Lumbers ER, Gunn AJ, Zhang DY, Wu JJ, Maxwell L, Bennet L (2001) Nonimmune hydrops fetalis and activation of the renin-angiotensin system after asphyxia in preterm fetal sheep. Am J Physiol Regul Integr Comp Physiol 280(4):R1045\u2013R1051","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"issue":"5","key":"9860_CR14","first-page":"59","volume":"95","author":"M Palanisamy","year":"2018","unstructured":"Palanisamy M, Manokaran S, Senthilkumar G, Raja S, Prabaharan V, Rajkumar R, Jayaganthan P (2018) Dystocia Due to Fetal Anasarca in a Spitz Bitch. Indian Vet J 95(5):59\u201360","journal-title":"Indian Vet J"},{"key":"9860_CR15","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/j.exppara.2016.02.003","volume":"164","author":"D Robbe","year":"2016","unstructured":"Robbe D, Passarelli A, Gloria A, Di Cesare A, Capelli G, Iorio R, Traversa D (2016) Neospora Caninum Seropositivity and reproductive risk factors in dogs. Exp Parasitol 164:31\u201335","journal-title":"Exp Parasitol"},{"issue":"4","key":"9860_CR16","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1007\/s10024-001-0260-6","volume":"5","author":"MM Rodr\u00edguez","year":"2002","unstructured":"Rodr\u00edguez MM, Chaves F, Romaguera RL, Ferrer PL, De la Guardia C, Bruce JH (2002) Value of autopsy in nonimmune Hydrops Fetalis: series of 51 stillborn fetuses. Pediatr Dev Pathol 5(4):365\u2013374","journal-title":"Pediatr Dev Pathol"},{"issue":"1","key":"9860_CR17","first-page":"2","volume":"21","author":"PE Shewen","year":"1980","unstructured":"Shewen PE (1980) Chlamydial infection in animals: a review. Can Vet J 21(1):2\u201311","journal-title":"Can Vet J"},{"issue":"1","key":"9860_CR18","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1111\/j.1439-0442.1972.tb00287.x","volume":"19","author":"JS van der Linde-Sipman","year":"1972","unstructured":"van der Linde-Sipman JS, Mullink JWMA (1972) Hydrops Fetalis in the dog; a record of ten cases. Zentralbl Veterin\u00e4rmed Reihe A 19(1):8\u201314","journal-title":"Zentralbl Veterin\u00e4rmed Reihe A"},{"key":"9860_CR19","first-page":"95","volume-title":"Neonatologia veterinaria","author":"MC Veronesi","year":"2013","unstructured":"Veronesi MC (2013) Patologie neonatali. In: Neonatologia veterinaria. EdiSES, Napoli, pp 95\u201397"},{"key":"9860_CR20","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.micpath.2014.07.011","volume":"75","author":"W Wang","year":"2014","unstructured":"Wang W, Gao X, Guo M, Zhang W, Song X, Wang T, Zhang Z, Jiang H, Cao Y, Zhang N (2014) Leptospira interrogans induces uterine inflammatory responses and abnormal expression of extracellular matrix proteins in dogs. Microb Pathog 75:1\u20136","journal-title":"Microb Pathog"}],"container-title":["Veterinary Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11259-021-09860-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11259-021-09860-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11259-021-09860-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,23]],"date-time":"2022-05-23T05:11:28Z","timestamp":1653282688000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11259-021-09860-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,2]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["9860"],"URL":"https:\/\/doi.org\/10.1007\/s11259-021-09860-w","relation":{},"ISSN":["0165-7380","1573-7446"],"issn-type":[{"value":"0165-7380","type":"print"},{"value":"1573-7446","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,2]]},"assertion":[{"value":"6 August 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 November 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 December 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The bitch involved in this case report was included in a study approved by University of Padova Ethical committee (Project \u201cClinical use of fetal gastrointestinal motility for the prediction of parturition date in the canine species\u201d nr 69\/2018). Due to the patological findings described in this case report, the bitch was excluded from the study and treated as a clinical case. All procedures performed complied with the therapeutics protocols.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Informed consent was obtained.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Informed consent was obtained.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no conflict of interest.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest\/competing interests"}}]}}