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The dog exhibited clinical signs such as apathy, vomiting, and bloody diarrhea. After confirming CPV-2 infection with a commercial snap test, intensive therapy was initiated. The dog succumbed within 48\u00a0h of admission. A rectal swab sample was collected, CPV-2 was examined using the PCR method, and sequenced. The virus detected in the patient was related to strains of CPV-2c of Asian origin and unrelated to European CPV-2b strains. The sequence had genetic signatures typical of Asian strains (VP2: 5Gly, 267Tyr, 324Ile, 370Arg, and 440Thr). Phylogenetic analysis classified this strain as similar to Asian strains of CPV-2c. It is believed to be derived from an Asian strain similar to CPV-2c that acquired the 426Asp mutation. With this finding, we present the first evidence of an Asian-like CPV-2b strain in the territory of Slovakia.<\/jats:p>","DOI":"10.1007\/s11259-024-10492-z","type":"journal-article","created":{"date-parts":[[2024,8,9]],"date-time":"2024-08-09T10:02:47Z","timestamp":1723197767000},"page":"3253-3262","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["The first evidence of Asian-like CPV-2b in Slovakia in a vaccinated dog with an acute fatal course of parvovirus infection: a case report"],"prefix":"10.1007","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-6371-9359","authenticated-orcid":false,"given":"Andrea","family":"Pelegrinov\u00e1","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3464-8502","authenticated-orcid":false,"given":"Patr\u00edcia","family":"Petrou\u0161kov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8559-3559","authenticated-orcid":false,"given":"\u013dubo\u0161","family":"Koryt\u00e1r","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4434-1443","authenticated-orcid":false,"given":"Anna","family":"Ondrejkov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7480-1167","authenticated-orcid":false,"given":"Monika","family":"Dr\u00e1\u017eovsk\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3008-0908","authenticated-orcid":false,"given":"Boris","family":"Vojtek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0508-398X","authenticated-orcid":false,"given":"Jana","family":"Moj\u017ei\u0161ov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3663-8765","authenticated-orcid":false,"given":"Mari\u00e1n","family":"Proke\u0161","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-6534-0637","authenticated-orcid":false,"given":"Maro\u0161","family":"Kosti\u010d\u00e1k","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-5614-5877","authenticated-orcid":false,"given":"\u013dubica","family":"Z\u00e1kutn\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9424-8765","authenticated-orcid":false,"given":"Michal","family":"Doln\u00edk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9562-3224","authenticated-orcid":false,"given":"Ren\u00e9","family":"Mandel\u00edk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,8,9]]},"reference":[{"key":"10492_CR1","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.vetmic.2017.08.019","volume":"210","author":"KD Altman","year":"2017","unstructured":"Altman KD, Kelman M, Ward MP (2017) Are vaccine strain, type or administration protocol risk factors for canine parvovirus vaccine failure? 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