{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T00:30:40Z","timestamp":1789000240757,"version":"build-2803163510"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,11,15]],"date-time":"2024-11-15T00:00:00Z","timestamp":1731628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,11,15]],"date-time":"2024-11-15T00:00:00Z","timestamp":1731628800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Vet Res Commun"],"published-print":{"date-parts":[[2025,2]]},"DOI":"10.1007\/s11259-024-10601-y","type":"journal-article","created":{"date-parts":[[2024,11,15]],"date-time":"2024-11-15T07:45:55Z","timestamp":1731656755000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Vascular hamartoma in horse limbs: presentation, diagnosis, and treatment of two case studies"],"prefix":"10.1007","volume":"49","author":[{"given":"Emanuel Vitor Pereira","family":"Apolonio","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"La\u00eds Loiola","family":"Gobbo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalia Gouveia","family":"Woiblet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando Carmona","family":"Dinau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mateus Siqueira","family":"Pyles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorena Cardozo","family":"Ferrari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana","family":"de Moura Alonso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Liz Garcia","family":"Alves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,11,15]]},"reference":[{"key":"10601_CR1","doi-asserted-by":"publisher","unstructured":"Adamo P, Ladomery MR (2016) The oncogene ERG: A key factor in prostate cancer. In Oncogene,\u00a0vol 35, issue 4, pp 403\u2013414. Nature Publishing Group. https:\/\/doi.org\/10.1038\/onc.2015.109","DOI":"10.1038\/onc.2015.109"},{"key":"10601_CR2","doi-asserted-by":"publisher","unstructured":"Barker WHJ, Perkins JD, Witte TH (2013) Three horses with bilateral sinonasal progressive haematomas not associated with the ethmoidal labyrinth. Equine Vet Educ 25(10):503\u2013507. https:\/\/doi.org\/10.1111\/eve.12015","DOI":"10.1111\/eve.12015"},{"issue":"6","key":"10601_CR3","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1177\/1040638714548681","volume":"26","author":"N Borel","year":"2014","unstructured":"Borel N, Grest P, Junge H, Wehrli Eser M (2014) Vascular hamartoma in the central nervous system of a foal. J Vet Diagn Invest 26(6):805\u2013809. https:\/\/doi.org\/10.1177\/1040638714548681","journal-title":"J Vet Diagn Invest"},{"key":"10601_CR4","doi-asserted-by":"publisher","unstructured":"Brown DL, Anderson M, Cullen JM (2007) Mesenchymal hamartoma of the liver in a late-term equine fetus. Vet Pathol\u00a044. https:\/\/doi.org\/10.1354\/vp.44-1-100","DOI":"10.1354\/vp.44-1-100"},{"key":"10601_CR5","doi-asserted-by":"publisher","unstructured":"Brunson BL, Taintor J, Newton J, Schumacher J, Christman U (2006) Vascular hamartoma in the tongue of a horse. J Equine Vet Sci 26(6):275\u2013277. https:\/\/doi.org\/10.1016\/j.jevs.2006.04.010","DOI":"10.1016\/j.jevs.2006.04.010"},{"key":"10601_CR6","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.jevs.2018.02.017","volume":"67","author":"NI Busse","year":"2018","unstructured":"Busse NI, Paredes EA, Bustamante HA, Ansoleaga N, Uberti B (2018) Periurethral vascular hamartoma in a 6-month-old foal with idiopathic hematuria: new differential diagnosis. J Equine Vet Sci 67:19\u201322. https:\/\/doi.org\/10.1016\/j.jevs.2018.02.017","journal-title":"J Equine Vet Sci"},{"issue":"1","key":"10601_CR7","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1111\/j.1751-0813.1997.tb13821.x","volume":"75","author":"C Colbourne","year":"1997","unstructured":"Colbourne C, Yovich J, Richards R, Rose K, Huxtable C (1997) Vascular hamartomas of the dorsal carpal region in three young thoroughbred horses. Aust Vet J 75(1):20\u201323. https:\/\/doi.org\/10.1111\/j.1751-0813.1997.tb13821.x","journal-title":"Aust Vet J"},{"issue":"15","key":"10601_CR8","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1136\/vr.154.15.474","volume":"154","author":"N Collins","year":"2004","unstructured":"Collins N, Kelly G, Pollock PJ, McAllister H, Schumacher J (2004) Subcutaneous fibrous hamartoma in a foal. Vet Rec 154(15):474\u2013476. https:\/\/doi.org\/10.1136\/vr.154.15.474","journal-title":"Vet Rec"},{"issue":"8","key":"10601_CR9","doi-asserted-by":"publisher","first-page":"e337","DOI":"10.1111\/eve.13550","volume":"34","author":"F Conti","year":"2022","unstructured":"Conti F, Poujet L, Delverdier M, Lallemand EA, Benoit J (2022) High dose rate interstitial 192-Ir brachytherapy for the treatment of a recurrent dermal vascular hamartoma in a horse. Equine Vet Educ 34(8):e337\u2013e343. https:\/\/doi.org\/10.1111\/eve.13550","journal-title":"Equine Vet Educ"},{"issue":"6","key":"10601_CR10","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1016\/j.jvc.2018.09.002","volume":"20","author":"MJ DiVincenzo","year":"2018","unstructured":"DiVincenzo MJ, Bonagura JD, Rings L, Burns TA, Cianciolo RE, Kohnken R (2018) Cardiovascular images: vascular hamartoma of the mitral valve in a horse. J Vet Cardiol 20(6):399\u2013404. https:\/\/doi.org\/10.1016\/j.jvc.2018.09.002","journal-title":"J Vet Cardiol"},{"key":"10601_CR11","doi-asserted-by":"publisher","unstructured":"Dunkel B, Shokek AB, Wilkins PA (2004) Congenital cystic polypoid rectal hamartoma in a newborn foal. In Brief Communications and Case Reports Vet Pathol,\u00a0vol.41, issue 6. https:\/\/doi.org\/10.1354\/vp.41-6-700","DOI":"10.1354\/vp.41-6-700"},{"issue":"3","key":"10601_CR12","doi-asserted-by":"publisher","first-page":"117","DOI":"10.5414\/NP300817","volume":"34","author":"MA Haber","year":"2015","unstructured":"Haber, M. A., Iranmahboob, A., Thomas, C., Liu, M., Najjar, A., & Zagzag, D. (2015). ERG is a novel and reliable marker for endothelial cells in central nervous system tumors. Clinical neuropathology, 34(3), 117.\u00a0https:\/\/doi.org\/10.5414\/NP300817","journal-title":"Clinical neuropathology"},{"key":"10601_CR13","unstructured":"Hargis AM, McElwain TF (1984) Vascular neoplasia in the skin of horses. J Am Vet Med Assoc\u00a0184(9):1121\u20131124"},{"issue":"4","key":"10601_CR14","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1892\/0891-6640(2005)19[564:HIYH]2.0.CO;2","volume":"19","author":"I Johns","year":"2005","unstructured":"Johns I, Stephen JO, Piero D, Richardson F, D. W., Wilkins PA (2005) Hemangiosarcoma in 11 young horses. J Vet Intern Med 19(4):564\u2013570. https:\/\/doi.org\/10.1892\/0891-6640(2005)19[564:HIYH]2.0.CO;2","journal-title":"J Vet Intern Med"},{"key":"10601_CR15","doi-asserted-by":"publisher","unstructured":"Knottenbelt, Patterson-Kane J, Snalune K (2015) Equine Clinical Oncology. https:\/\/doi.org\/10.1016\/C2009-0-61955-3","DOI":"10.1016\/C2009-0-61955-3"},{"key":"10601_CR16","doi-asserted-by":"publisher","unstructured":"Leitzen E, Stumpf S, Zimmermann C, Bienert-Zeit A, Hellige M, Baumg\u00e4rtner W, Puff C (2020) A rare case of vascular proliferation in the Mandible of a juvenile horse. Front Vet Sci 7. https:\/\/doi.org\/10.3389\/fvets.2020.573540","DOI":"10.3389\/fvets.2020.573540"},{"issue":"2","key":"10601_CR17","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1080\/01652176.2003.9695146","volume":"25","author":"W Misdorp","year":"2003","unstructured":"Misdorp W (2003) Congenital tumours and tumour-like lesions in domestic animals. 3. Horses. A review. Vet Q 25(2):61\u201371. https:\/\/doi.org\/10.1080\/01652176.2003.9695146","journal-title":"Vet Q"},{"issue":"5","key":"10601_CR18","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1111\/eve.12150","volume":"28","author":"B Musterle","year":"2016","unstructured":"Musterle B, Hagen R, Grest P, K\u00fcmmerle J (2016) Diagnostic imaging, surgical treatment and histopathological findings of a vascular hamartoma in a 2-year-old horse. Equine Vet Educ 28(5):253\u2013258. https:\/\/doi.org\/10.1111\/eve.12150","journal-title":"Equine Vet Educ"},{"issue":"5","key":"10601_CR19","doi-asserted-by":"publisher","first-page":"352","DOI":"10.29271\/jcpsp.2018.05.352","volume":"28","author":"N Naeem","year":"2018","unstructured":"Naeem N, Mushtaq S, Akhter N, Hussain M, Hassan U (2018) Effectiveness of vascular markers (immunohistochemical stains) in soft tissue sarcomas. J Coll Physicians Surg Pakistan 28(5):352\u2013356. https:\/\/doi.org\/10.29271\/jcpsp.2018.05.352","journal-title":"J Coll Physicians Surg Pakistan"},{"issue":"6","key":"10601_CR20","first-page":"547","volume":"55","author":"M Nolf","year":"2014","unstructured":"Nolf M, Maninchedda U, Belluco S, Lepage O, Cador\u00e9 JL (2014) Cecal vascular hamartoma causing recurrent colic in an arabian mare. Can Vet J 55(6):547\u2013550 PMID: 24891636; PMCID: PMC4022021","journal-title":"Can Vet J"},{"issue":"10","key":"10601_CR21","doi-asserted-by":"publisher","first-page":"e431","DOI":"10.1111\/eve.13523","volume":"34","author":"C Osborne","year":"2022","unstructured":"Osborne C, Elce YA, Meehan L, Davern AJ, Lescun TB (2022) Neoplasia within the equine foot: a retrospective case series of four horses. Equine Vet Educ 34(10):e431\u2013e437. https:\/\/doi.org\/10.1111\/eve.13523","journal-title":"Equine Vet Educ"},{"issue":"6","key":"10601_CR22","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1111\/j.2042-3306.1987.tb02658.x","volume":"19","author":"H Platt","year":"1987","unstructured":"Platt H (1987) Vascular malformations and angiomatous lesions in horses: a review of 10 cases. Equine Vet J 19(6):500\u2013504. https:\/\/doi.org\/10.1111\/j.2042-3306.1987.tb02658.x","journal-title":"Equine Vet J"},{"key":"10601_CR23","doi-asserted-by":"publisher","unstructured":"Rhyan JC, Dandrea GH, Smith LS (1981) Congenital Ovarian Vascular Hamartoma in a Horse. https:\/\/doi.org\/10.1177\/030098588101800118","DOI":"10.1177\/030098588101800118"},{"issue":"3","key":"10601_CR24","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1111\/j.2042-3306.1984.tb01911.x","volume":"16","author":"F Roperto","year":"1984","unstructured":"Roperto F, Galati P (1984) Mixed hamartoma of the liver in an equine foetus. Equine Vet J 16(3):218\u2013220. https:\/\/doi.org\/10.1111\/j.2042-3306.1984.tb01911.x","journal-title":"Equine Vet J"},{"issue":"4","key":"10601_CR25","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1111\/j.1439-0442.2006.00818.x","volume":"53","author":"S Saifzadeh","year":"2006","unstructured":"Saifzadeh S, Derakhshanfar A, Shokouhi F, Hashemi M, Mazaheri R (2006) Vascular hamartoma as the cause of Hind limb lameness in a horse. J Vet Med Ser A: Physiol Pathol Clin Med 53(4):202\u2013204. https:\/\/doi.org\/10.1111\/j.1439-0442.2006.00818.x","journal-title":"J Vet Med Ser A: Physiol Pathol Clin Med"},{"issue":"2","key":"10601_CR26","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1111\/j.2042-3292.2010.00138.x","volume":"23","author":"T Salazar","year":"2011","unstructured":"Salazar T, Caldwell F, Joiner K, Parra-Sanchez A, Stewart AJ (2011) Laparoscopic assisted surgical removal of a congenital rectal hamartoma in a foal. Equine Vet Educ 23(2):55\u201361. https:\/\/doi.org\/10.1111\/j.2042-3292.2010.00138.x","journal-title":"Equine Vet Educ"},{"issue":"3","key":"10601_CR27","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1111\/j.1532-950X.1998.tb00116.x","volume":"27","author":"J Schumacher","year":"1998","unstructured":"Schumacher J, Yarbrough T, Pascoe J, Woods P, Meagher D, Honnas C (1998) Transendoscopic chemical ablation of Progressive Ethmoidal hematomas in standing horses. Vet Surg 27(3):175\u2013181. https:\/\/doi.org\/10.1111\/j.1532-950X.1998.tb00116.x","journal-title":"Vet Surg"},{"key":"10601_CR28","doi-asserted-by":"publisher","unstructured":"Segabinazzi LGTM, Apolonio EVP, Tongu EA, Paccola W, Vianna D, Fonseca-Alves CE, Alvarenga MA (2021) Primary uterine hemangiosarcoma in a thoroughbred: a case report. J Equine Vet Sci 106. https:\/\/doi.org\/10.1016\/j.jevs.2021.103768","DOI":"10.1016\/j.jevs.2021.103768"},{"key":"10601_CR29","doi-asserted-by":"publisher","unstructured":"Sulliva HC, Edgar MA, Cohen C, Kovach CK, HooKim K, Reid MD (2015) The utility of ERG, CD31 and CD34 in the cytological diagnosis of angiosarcoma: an analysis of 25 cases. J Clin Pathol 68(1):44\u201350. https:\/\/doi.org\/10.1136\/jclinpath-2014-202629","DOI":"10.1136\/jclinpath-2014-202629"},{"issue":"4","key":"10601_CR30","doi-asserted-by":"publisher","first-page":"844","DOI":"10.1177\/0300985815622971","volume":"53","author":"KR Taylor","year":"2016","unstructured":"Taylor KR, MacKay RJ, Nelson EA, Stieler AL, Roberts JF, Castleman WL (2016) Spinal cord Hamartomatous Myelodysplasia in 2 horses with clinical neurologic deficits. Vet Pathol 53(4):844\u2013846. https:\/\/doi.org\/10.1177\/0300985815622971","journal-title":"Vet Pathol"},{"key":"10601_CR31","doi-asserted-by":"publisher","unstructured":"Theoret C, Schumacher J (2017) Equine Wound Management. https:\/\/doi.org\/10.1002\/9781118999219. www.wiley.com\/go\/theoret\/wound","DOI":"10.1002\/9781118999219"},{"issue":"7","key":"10601_CR32","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1111\/j.1532-950X.2013.12055.x","volume":"42","author":"CL Theoret","year":"2013","unstructured":"Theoret CL, Olutoye OO, Parnell LKS, Hicks J (2013) Equine exuberant granulation tissue and human keloids: a comparative histopathologic study. Vet Surg 42(7):783\u2013789. https:\/\/doi.org\/10.1111\/j.1532-950X.2013.12055.x","journal-title":"Vet Surg"},{"key":"10601_CR33","doi-asserted-by":"publisher","unstructured":"van Delft TVAF, Pollaris E, Gielen I, Vanderperren K, Tuerlinckx L, Vlaminck L (2018) Maxillary bone cysts in two horses: diagnosis and treatment including intralesional formalin injection. Equine Vet Educ 30(11):583\u2013590. https:\/\/doi.org\/10.1111\/eve.12754","DOI":"10.1111\/eve.12754"},{"issue":"2 SPEC ISS","key":"10601_CR34","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1053\/j.ctep.2004.08.012","volume":"3","author":"JM Wilmink","year":"2004","unstructured":"Wilmink JM, Van Weeren PR (2004) Treatment of exuberant granulation tissue. Clin Techniques Equine Pract 3(2 SPEC ISS):141\u2013147. https:\/\/doi.org\/10.1053\/j.ctep.2004.08.012","journal-title":"Clin Techniques Equine Pract"},{"issue":"10","key":"10601_CR35","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1111\/eve.13407","volume":"33","author":"JC Wise","year":"2021","unstructured":"Wise JC, Crosby DE, Walton AN, Neef A, Shearer PL, Woodward DJ, Hilbert BJ (2021) A tumour of vascular origin in a horse. Equine Vet Educ 33(10):509. https:\/\/doi.org\/10.1111\/eve.13407","journal-title":"Equine Vet Educ"},{"issue":"5","key":"10601_CR36","doi-asserted-by":"publisher","first-page":"1051","DOI":"10.1177\/1040638711416852","volume":"23","author":"K Yasuno","year":"2011","unstructured":"Yasuno K, Kobayashi R, Ohmuro T, Kamiie J, Sahara H, Shirota K (2011) Caudal vascular hamartoma accompanied by aberrant arteriovenous structures in a dog. J Vet Diagn Invest 23(5):1051\u20131055. https:\/\/doi.org\/10.1177\/1040638711416852","journal-title":"J Vet Diagn Invest"},{"issue":"11","key":"10601_CR37","doi-asserted-by":"publisher","first-page":"767","DOI":"10.1016\/j.jevs.2012.02.017","volume":"32","author":"R Zafra","year":"2012","unstructured":"Zafra R, Estepa JC, Aguilera-Tejero E, Jaber JR, Bautista MJ, Pacheco I, P\u00e9rez J (2012) Clinicopathological features of hemangioma in two young horses. J Equine Vet Sci 32(11):767\u2013769. https:\/\/doi.org\/10.1016\/j.jevs.2012.02.017","journal-title":"J Equine Vet Sci"}],"container-title":["Veterinary Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11259-024-10601-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11259-024-10601-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11259-024-10601-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T10:07:36Z","timestamp":1738404456000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11259-024-10601-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,15]]},"references-count":37,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["10601"],"URL":"https:\/\/doi.org\/10.1007\/s11259-024-10601-y","relation":{},"ISSN":["0165-7380","1573-7446"],"issn-type":[{"value":"0165-7380","type":"print"},{"value":"1573-7446","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,15]]},"assertion":[{"value":"20 August 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 November 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 November 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"The study described in this manuscript involved the use of non-experimental horses. The owners have provided consent for veterinary clinical care for the individual patient at the S\u00e3o Paulo State University \u2014School of Veterinary Medicine and Animal Science (FMVZ\/UNESP), Botucatu, Brazil, and for the publication of their pet\u2019s data. Therefore, ethical approval from a committee was not specifically required for publication.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}],"article-number":"8"}}