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The ability of <jats:italic>L. reuteri<\/jats:italic> B1\/1 to effectively modulate the mucosal immune response under pretreatment conditions in S. Enteritidis PT4 infection in a chicken ileal explant model was confirmed. In addition, our obtained results point to the fact that the new chicken ileum explant model could be a suitable model to investigate or test the influence of natural substances such as probiotic bacteria in the interaction with the intestine as well as pathogenic microorganisms. In addition, the results of our study may contribute to a deeper understanding of the action of newly isolated probiotic bacteria at the intestinal level using ex vivo models such as chicken ileum explant, which are able to mimic in vivo conditions sufficiently.<\/jats:p>","DOI":"10.1007\/s11259-024-10609-4","type":"journal-article","created":{"date-parts":[[2024,11,23]],"date-time":"2024-11-23T05:46:40Z","timestamp":1732340800000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Limosilactobacillus reuteri B1\/1 modulated the intestinal immune response in preventing Salmonella Enteritidis PT4 infection in a chicken ileal explant model"],"prefix":"10.1007","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8424-367X","authenticated-orcid":false,"given":"Viera","family":"Karaffov\u00e1","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4293-574X","authenticated-orcid":false,"given":"Zuzana","family":"Ki\u0161\u0161ov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7444-7348","authenticated-orcid":false,"given":"Csilla","family":"T\u00f3thov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2323-9634","authenticated-orcid":false,"given":"Patrik","family":"Tr\u00e1j","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5992-6797","authenticated-orcid":false,"given":"M\u00e1t\u00e9","family":"Mackei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7371-9444","authenticated-orcid":false,"given":"G\u00e1bor","family":"M\u00e1tis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,11,23]]},"reference":[{"key":"10609_CR1","doi-asserted-by":"publisher","first-page":"1835","DOI":"10.1111\/jpn.13454","volume":"104","author":"ME Abd El-Hack","year":"2020","unstructured":"Abd El-Hack ME, El-Saadony MT, Shafi ME, Qattan SYA, Batiha GE, Khafaga AF, Abdel-Moneim AE, Alagawany M (2020) Probiotics in poultry feed: a comprehensive review. 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