{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,8]],"date-time":"2025-05-08T08:40:02Z","timestamp":1746693602534,"version":"3.40.5"},"reference-count":71,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T00:00:00Z","timestamp":1744848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T00:00:00Z","timestamp":1744848000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100005672","name":"Funda\u00e7\u00e3o de Apoio ao Desenvolvimento do Ensino, Ci\u00eancia e Tecnologia do Estado de Mato Grosso do Sul","doi-asserted-by":"crossref","award":["901\/2022"],"award-info":[{"award-number":["901\/2022"]}],"id":[{"id":"10.13039\/501100005672","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Vet Res Commun"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1007\/s11259-025-10739-3","type":"journal-article","created":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T04:14:59Z","timestamp":1744863299000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Residual depletion of eugenol as an anesthetic in growing phase pacu (Piaractus mesopotamicus)"],"prefix":"10.1007","volume":"49","author":[{"given":"Caio Francisco Santana","family":"Farias","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jayme Aparecido","family":"Povh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruy Alberto Caetano Corr\u00eaa","family":"Filho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea Maria","family":"de Ara\u00fajo Gabriel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia Andrea Lima","family":"Cardoso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adryadine Almeida","family":"da Costa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ant\u00f4nio Francisco","family":"Oliveira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriela Tomas","family":"Jer\u00f4nimo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maur\u00edcio Later\u00e7a","family":"Martins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arlene Sobrinho","family":"Ventura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,4,17]]},"reference":[{"key":"10739_CR1","doi-asserted-by":"publisher","unstructured":"Afonso LOB (2020) Identifying and managing maladaptive physiological responses to aquaculture stressors. Fish Physiol 38:163\u2013191.\u00a0https:\/\/doi.org\/10.1016\/bs.fp.2020.10.002","DOI":"10.1016\/bs.fp.2020.10.002"},{"key":"10739_CR2","doi-asserted-by":"publisher","first-page":"690","DOI":"10.1111\/jpn.13711","volume":"106","author":"I Ahmed","year":"2022","unstructured":"Ahmed I, Jan K, Fatma S, Dawood MAO (2022) Muscle proximate composition of various food fish species and their nutritional significance: a review. J Anim Physiol Anim Nutr (Berl) 106:690\u2013719. https:\/\/doi.org\/10.1111\/jpn.13711","journal-title":"J Anim Physiol Anim Nutr (Berl)"},{"key":"10739_CR3","first-page":"4","volume":"28","author":"J Allen","year":"1986","unstructured":"Allen J, Hunn J (1986) Fate and distribution studies of some drugs used in aquaculture. Vet Hum Toxicol 28:4\u201321","journal-title":"Vet Hum Toxicol"},{"key":"10739_CR4","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/5432497","author":"A Assefa","year":"2018","unstructured":"Assefa A, Abunna F (2018) Maintenance of fish health in aquaculture: review of epidemiological approaches for prevention and control of infectious disease of fish. Vet Med Int. https:\/\/doi.org\/10.1155\/2018\/5432497","journal-title":"Vet Med Int"},{"key":"10739_CR5","doi-asserted-by":"publisher","unstructured":"Benovit SC, Gressler LT, Silva L de L, Garcia L de O, Okamoto MH, Pedron J dos S, Sampaio LA, Rodrigues RV, Heinzmann BM, Baldisserotto B\u00a0(2012) Anesthesia and transport of Brazilian flounder, Paralichthys orbignyanus, with essential oils of Aloysia gratissima and Ocimum gratissimum. J World Aquac Soc. https:\/\/doi.org\/10.1111\/J.1749-7345.2012.00604.X","DOI":"10.1111\/J.1749-7345.2012.00604.X"},{"key":"10739_CR6","doi-asserted-by":"publisher","first-page":"6346","DOI":"10.1590\/1414-431x20176346","volume":"50","author":"AE Bianchini","year":"2017","unstructured":"Bianchini AE, Garlet QI, Cunha JA, da, Bandeira Junior G, Brusque ICM, Salbego J, Heinzmann BM, Baldisserotto B (2017) Monoterpenoids (thymol, carvacrol and S-(+)-linalool) with anesthetic activity in silver catfish (Rhamdia quelen): evaluation of acetylcholinesterase and GABAergic activity. Braz J Med Biol Res 50:6346. https:\/\/doi.org\/10.1590\/1414-431x20176346","journal-title":"Braz J Med Biol Res"},{"key":"10739_CR7","doi-asserted-by":"publisher","unstructured":"Bianchini AE, Garlet QI, Rodrigues P, Souza C de F, Silva L de L, Santos AC dos, Heinzmann BM, Baldisserotto B\u00a0(2019) B Pharmacokinetics of S-(+)-linalool in silver catfish (Rhamdia quelen) after immersion bath: an anesthetic for aquaculture. Aquaculture 506:302\u2013307. https:\/\/doi.org\/10.1016\/j.aquaculture.2019.03.044","DOI":"10.1016\/j.aquaculture.2019.03.044"},{"key":"10739_CR8","doi-asserted-by":"publisher","first-page":"735637","DOI":"10.1016\/j.aquaculture.2020.735637","volume":"529","author":"AE Bianchini","year":"2020","unstructured":"Bianchini AE, Rodrigues P, Barbosa LB, Bandeira Junior G, Souza C, de Heinzmann F, Baldisserotto BM B (2020) Tissue distribution and elimination of S-(+)-linalool in silver catfish (Rhamdia quelen). Aquaculture 529:735637. https:\/\/doi.org\/10.1016\/j.aquaculture.2020.735637","journal-title":"Aquaculture"},{"key":"10739_CR9","doi-asserted-by":"publisher","first-page":"1229","DOI":"10.3390\/molecules26051229","volume":"26","author":"B Bobrowska-Korczak","year":"2021","unstructured":"Bobrowska-Korczak B, Stawarska A, Szterk A, Ofiara K, Czerwonka M, Giebultowicz J (2021) Determination of pharmaceuticals, heavy metals, and oxysterols in fish muscle. Molecules 26:1229. https:\/\/doi.org\/10.3390\/molecules26051229","journal-title":"Molecules"},{"key":"10739_CR10","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4615-5407-3","volume-title":"Water quality for pond aquaculture","author":"CE Boyd","year":"1998","unstructured":"Boyd CE (1998) Water quality for pond aquaculture, 1st edn. Station Auburn University, Alabama","edition":"1"},{"key":"10739_CR11","doi-asserted-by":"publisher","first-page":"578","DOI":"10.1111\/jwas.12714","volume":"51","author":"CE Boyd","year":"2020","unstructured":"Boyd CE, D\u2019Abramo LR, Glencross BD, Huyben DC, Juarez LM, Lockwood GS, Mcnevin AA, Tacon AGJ, Teletchea F, Tomasso JR Jr, Tucker CS, Valenti WC (2020) Achieving sustainable aquaculture: historical and current perspectives and future needs and challenges. J World Aquac Soc 51:578\u2013633. https:\/\/doi.org\/10.1111\/jwas.12714","journal-title":"J World Aquac Soc"},{"key":"10739_CR12","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1002\/ar.1092130405","volume":"213","author":"JA Brown","year":"1985","unstructured":"Brown JA (1985) Renal microvasculature of the rainbow trout, Salmo gairdneri: scanning electron microscopy of corrosion casts of glomeruli. Anat Rec 213:505\u2013513. https:\/\/doi.org\/10.1002\/ar.1092130405","journal-title":"Anat Rec"},{"key":"10739_CR13","doi-asserted-by":"publisher","DOI":"10.1017\/9781108819732.005","volume-title":"Contaminant bioaccumulation: Kinetics and modelling uptake mechanisms","author":"PG Campbell","year":"2022","unstructured":"Campbell PG, Hodson PV, Welbourn PM, Wright DA (2022) Contaminant bioaccumulation: kinetics and modelling uptake mechanisms. In: Ecotoxicology. Cambridge University Press, Cambridge, pp 60\u201397.\u00a0https:\/\/doi.org\/10.1017\/9781108819732.005"},{"key":"10739_CR14","doi-asserted-by":"publisher","first-page":"1249","DOI":"10.3390\/ijms18061249","volume":"18","author":"M Cataldi","year":"2017","unstructured":"Cataldi M, Vigliotti C, Mosca T et al (2017) Emerging role of the spleen in the pharmacokinetics of monoclonal antibodies, nanoparticles and exosomes. Int J Mol Sci 18:1249. https:\/\/doi.org\/10.3390\/ijms18061249","journal-title":"Int J Mol Sci"},{"key":"10739_CR15","doi-asserted-by":"publisher","first-page":"303","DOI":"10.3354\/meps136303","volume":"136","author":"JS Christiansen","year":"1996","unstructured":"Christiansen JS, Dalmo RA, Ingebrigtsen K (1996) Xenobiotic excretion in fish with aglomerular kidneys. Mar Ecol Prog Ser 136:303\u2013304. https:\/\/doi.org\/10.3354\/meps136303","journal-title":"Mar Ecol Prog Ser"},{"key":"10739_CR16","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1007\/s00343-019-9056-2","volume":"38","author":"W Cui","year":"2020","unstructured":"Cui W, Ma A, Huang Z, Wang X, Sun Z, Liu Z, Zhang W, Yang J, Zhang J, Qu J (2020) Transcriptomic analysis reveals putative osmoregulation mechanisms in the kidney of Euryhaline turbot Scophthalmus maximus responded to hyposaline seawater. J Oceanol Limnol 38:467\u2013479. https:\/\/doi.org\/10.1007\/s00343-019-9056-2","journal-title":"J Oceanol Limnol"},{"key":"10739_CR17","doi-asserted-by":"publisher","unstructured":"Cunha MA da, Barros FMC de, Garcia L de O, Veeck AP de L, Heinzmann BM, Loro VL, Emanuelli T, Baldisserotto B\u00a0(2010) Essential oil of Lippia alba: a new anesthetic for silver catfish, Rhamdia quelen. Aquaculture 306:403\u2013406. https:\/\/doi.org\/10.1016\/j.aquaculture.2010.06.014","DOI":"10.1016\/j.aquaculture.2010.06.014"},{"key":"10739_CR18","doi-asserted-by":"publisher","first-page":"216762","DOI":"10.1242\/jeb.216762","volume":"223","author":"NJ Dawson","year":"2020","unstructured":"Dawson NJ, Millet C, Selman C, Metcalfe NB (2020) Measurement of mitochondrial respiration in permeabilized fish gills. J Exp Biol 223:216762. https:\/\/doi.org\/10.1242\/jeb.216762","journal-title":"J Exp Biol"},{"key":"10739_CR19","doi-asserted-by":"publisher","first-page":"1144","DOI":"10.3390\/biom13071144","volume":"13","author":"DP de Sousa","year":"2023","unstructured":"de Sousa DP, Damasceno ROS, Amorati R, Elshabrawy HA, Bezerra DP, Nunes VR, Gomes RC, Lima TC (2023) Essential oils: chemistry and pharmacological activities. Biomolecules 13:1144. https:\/\/doi.org\/10.3390\/biom13071144","journal-title":"Biomolecules"},{"key":"10739_CR20","doi-asserted-by":"crossref","unstructured":"dos Santos AC, Cunha MA da\u00a0(2021) International legislation on drugs and biological products used in the sanitary management of aquatic animals. In: Aquaculture pharmacology. Elsevier, pp 347\u2013392","DOI":"10.1016\/B978-0-12-821339-1.00011-8"},{"key":"10739_CR21","doi-asserted-by":"publisher","unstructured":"Evans DH, Piermarini PM, Choe KP (2005) The multifunctional fish Gill: dominant site of gas exchange, osmoregulation, acid-base regulation, and excretion of nitrogenous waste. Physiol Rev 97\u2013177. https:\/\/doi.org\/10.1152\/physrev.00050.2003","DOI":"10.1152\/physrev.00050.2003"},{"key":"10739_CR22","volume-title":"The state of world fisheries and aquaculture 2022. Towards blue transformation","author":"FAO","year":"2022","unstructured":"FAO (2022) The state of world fisheries and aquaculture 2022. Towards blue transformation. FAO, Rome"},{"key":"10739_CR23","unstructured":"Farias CFS, Ferreira NL, Lopes EM, Dittrich CCL, Miranda GF, Ventura AS, Jer\u00f4nimo GT, Martins ML (2023a) Farmacocin\u00e9tica como ferramenta na avalia\u00e7\u00e3o de anest\u00e9sicos na aquicultura. In: Pilarski F, Tavares GC, Vallad\u00e3o GMR et al (eds) Sanidade de Organismos Aqu\u00e1ticos: Avan\u00e7os no diagn\u00f3stico, controle e monitoramento de doen\u00e7as, 1st edn. ABRAPOA, Belo Horizonte, pp 501\u2013520"},{"key":"10739_CR24","doi-asserted-by":"publisher","unstructured":"Farias CFS, Ventura AS, Jer\u00f4nimo GT, Cardoso CAL, Matos LV de, Silva GS da, Gon\u00e7alves LU, Povh JA, Martins ML\u00a0(2023b) Pharmacokinetics and metabolism of basil (Ocimum basilicum) essential oil as an anesthetic for tambaqui (Colossoma macropomum). Aquac Int 32:2923\u20132938. https:\/\/doi.org\/10.1007\/s10499-023-01304-3","DOI":"10.1007\/s10499-023-01304-3"},{"key":"10739_CR25","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1111\/faf.12731","volume":"24","author":"L F\u00e9lix","year":"2023","unstructured":"F\u00e9lix L, Vieira R, Monteiro SM, Ven\u00e2ncio C (2023) A meta-analytic review of monoterpene for fish anaesthesia. Fish Fish 24:367\u2013380. https:\/\/doi.org\/10.1111\/faf.12731","journal-title":"Fish Fish"},{"key":"10739_CR26","doi-asserted-by":"publisher","first-page":"735933","DOI":"10.1016\/j.aquaculture.2020.735933","volume":"530","author":"MV Freitas","year":"2021","unstructured":"Freitas MV, Lira LVG, Ariede RB, Agudelo JFG, de Oliveira Neto RR, Borges CHS, Mastrochirico-Filho VA, Garcia Neto BF, Carvalheiro R, Hashimoto DT (2021) Genotype by environment interaction and genetic parameters for growth traits in the neotropical fish pacu (Piaractus mesopotamicus). Aquaculture 530:735933. https:\/\/doi.org\/10.1016\/j.aquaculture.2020.735933","journal-title":"Aquaculture"},{"key":"10739_CR27","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1515\/pjvs-2015-0019","volume":"18","author":"P Gomu\u0142ka","year":"2015","unstructured":"Gomu\u0142ka P, Fornal E, Berecka B, Szmagara A, Ziomek E (2015) Pharmacokinetics of propofol in rainbow trout following bath exposure. Pol J Vet Sci 18:147\u2013152. https:\/\/doi.org\/10.1515\/pjvs-2015-0019","journal-title":"Pol J Vet Sci"},{"key":"10739_CR28","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1016\/j.aquaculture.2007.02.046","volume":"266","author":"SA Gu\u00e9nette","year":"2007","unstructured":"Gu\u00e9nette SA, Uhland FC, H\u00e9lie P, Beaudry F, Vachon P (2007) Pharmacokinetics of eugenol in rainbow trout (Oncorhynchus mykiss). Aquaculture 266:262\u2013265. https:\/\/doi.org\/10.1016\/j.aquaculture.2007.02.046","journal-title":"Aquaculture"},{"key":"10739_CR29","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1046\/j.1365-2885.2003.00454.x","volume":"26","author":"MK Hansen","year":"2003","unstructured":"Hansen MK, Nymoen U, Horsberg TE (2003) Pharmacokinetic and pharmacodynamic properties of metomidate in turbot (Scophthalmus maximus) and halibut (Hippoglossus hippoglossus). J Vet Pharmacol Ther 26:95\u2013103. https:\/\/doi.org\/10.1046\/j.1365-2885.2003.00454.x","journal-title":"J Vet Pharmacol Ther"},{"key":"10739_CR30","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1007\/978-1-4615-4703-7_5","volume-title":"Xenobiotics in fish","author":"WL Hayton","year":"1999","unstructured":"Hayton WL (1999) Considerations in Compartmental Pharmacokinetic Modeling in Fish. In: Smith DJ, Gingerich WH, Beconi-Barker MG (eds) Xenobiotics in Fish. Springer, Boston, MA. https:\/\/doi.org\/10.1007\/978-1-4615-4703-7_5"},{"key":"10739_CR31","doi-asserted-by":"publisher","first-page":"49","DOI":"10.5216\/cab.v14i1.13583","volume":"14","author":"CA Honorato","year":"2013","unstructured":"Honorato CA, Nunes C, da Carrilho S, Moraes ENVM G (2013) Effect of processing of diets with different levels of carbohydrates and lipids on body composition and fatty acid composition of filet of Piaractus mesopotamicus. Ci\u00eanc Anim Bras 14:49\u201358. https:\/\/doi.org\/10.5216\/cab.v14i1.13583","journal-title":"Ci\u00eanc Anim Bras"},{"key":"10739_CR32","doi-asserted-by":"publisher","first-page":"92424","DOI":"10.7554\/eLife.92424","volume":"13","author":"C Hu","year":"2024","unstructured":"Hu C, Zhang N, Hong Y, Tie R, Fan D, Lin A, Chen Y, Xiang L, Shao J (2024) Single-cell RNA sequencing unveils the hidden powers of zebrafish kidney for generating both hematopoiesis and adaptive antiviral immunity. Elife 13:92424. https:\/\/doi.org\/10.7554\/eLife.92424","journal-title":"Elife"},{"key":"10739_CR33","unstructured":"Japan Food Chemical Research Foundation (2022) MRL for agricultural chemicals, feed additives and veterinary medicines in foodstuffs. Dispon\u00edvel: https:\/\/www.ffcr.or.jp\/en\/zanryu\/mrls-of-agricultural-chemicals-feed-additives-and-veterinary-drugs-in-food\/-revision-of-mrls-of-agricultural-chemicals-feed-additives-and-veterinary-drugs-in-foods-september-1.html. Acesso em:06 jun. 2024"},{"key":"10739_CR34","doi-asserted-by":"publisher","first-page":"10882","DOI":"10.3390\/app112210882","volume":"11","author":"C Ke","year":"2021","unstructured":"Ke C, Liu Q, Huang K, Mo M, Chen H, Cheng B (2021) Effect of water temperature on the depletion of eugenol in sea bass under the simulated settings in handling and transport. Appl Sci (Switz) 11:10882. https:\/\/doi.org\/10.3390\/app112210882","journal-title":"Appl Sci (Switz)"},{"key":"10739_CR35","doi-asserted-by":"publisher","first-page":"4163","DOI":"10.1002\/bmc.4163","volume":"32","author":"Y Liu","year":"2017","unstructured":"Liu Y, Ai X, Li L, Li J, Yang H (2017) A fast and accurate isotope dilution GC-IT-MS\/MS method for determination of eugenol in different tissues of fish: application to a depletion study in Mandarin fish. Biomed Chromatogr 32:4163. https:\/\/doi.org\/10.1002\/bmc.4163","journal-title":"Biomed Chromatogr"},{"key":"10739_CR36","doi-asserted-by":"publisher","first-page":"668","DOI":"10.1080\/1040841X.2017.1295225","volume":"43","author":"A Marchese","year":"2017","unstructured":"Marchese A, Barbieri R, Coppo E, Orhan IE, Daglia M, Nabavi SF, Izadi M, Abdollahi M, Nabavi SM, Ajami M (2017) Antimicrobial activity of eugenol and essential oils containing eugenol: a mechanistic viewpoint. Crit Rev Microbiol 43:668\u2013689. https:\/\/doi.org\/10.1080\/1040841X.2017.1295225","journal-title":"Crit Rev Microbiol"},{"key":"10739_CR37","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/S0044-8486(96)01406-8","volume":"148","author":"JR Meinertz","year":"1996","unstructured":"Meinertz JR, Stehly GR, Gingerich WH (1996) Pharmacokinetics of benzocaine in rainbow trout (Oncorhynchus mykiss) after intraarterial dosing. Aquaculture 148:39\u201348. https:\/\/doi.org\/10.1016\/S0044-8486(96)01406-8","journal-title":"Aquaculture"},{"key":"10739_CR38","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/j.aquatox.2017.03.012","volume":"187","author":"I Mihaljevi\u0107","year":"2017","unstructured":"Mihaljevi\u0107 I, Popovi\u0107 M, \u017daja R, Marakovic N, Sinko G, Smital T (2017) Interaction between the zebrafish (Danio rerio) organic cation transporter 1 (Oct1) and endo- and xenobiotics. Aquat Toxicol 187:18\u201328. https:\/\/doi.org\/10.1016\/j.aquatox.2017.03.012","journal-title":"Aquat Toxicol"},{"key":"10739_CR39","doi-asserted-by":"publisher","unstructured":"Moreira AP, Oliveira FC, Ferreira AL, Almeida PR de, Costa DC, Cardoso CAL, Chaves FCM, Chagas EC, Campos CM de\u00a0(2024) Efficacy of essential oil from ginger (Zingiber officinale) for anesthesia and transport sedation of Pacu (Piaractus mesopotamicus). Fish Physiol Biochem 50:865\u2013880. https:\/\/doi.org\/10.1007\/s10695-024-01346-1","DOI":"10.1007\/s10695-024-01346-1"},{"key":"10739_CR40","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1016\/j.vaa.2018.02.005","volume":"45","author":"A Oda","year":"2018","unstructured":"Oda A, Messenger KM, Carbajal L, Posner LP, Gardner BR, Hammer SH, Cerreta AJ, Lewbart GA, Bailey KM (2018) Pharmacokinetics and pharmacodynamic effects in Koi carp (Cyprinus carpio) following immersion in propofol. Vet Anaesth Analg 45:529\u2013538. https:\/\/doi.org\/10.1016\/j.vaa.2018.02.005","journal-title":"Vet Anaesth Analg"},{"key":"10739_CR41","doi-asserted-by":"publisher","first-page":"646","DOI":"10.1111\/jtxs.12372","volume":"49","author":"Y Pav\u00f3n","year":"2018","unstructured":"Pav\u00f3n Y, Cian RE, Soldini MAC, Hern\u00e1ndez DR, Sanchez S, Drago SR (2018) Sensory and instrumental textural changes in fillets from Pac\u00fa (Piaractus mesopotamicus) fed different diets. J Texture Stud 49:646\u2013652. https:\/\/doi.org\/10.1111\/jtxs.12372","journal-title":"J Texture Stud"},{"key":"10739_CR42","doi-asserted-by":"publisher","first-page":"2661","DOI":"10.24297\/jac.v10i5.6967","volume":"10","author":"RA Pereira","year":"2014","unstructured":"Pereira RA, Saczk AA, Okamura D, Cardosos M, das G, Costa LS, Santiago WD, Souza TM, de Lima RMF, Rosa PV (2014) Quantification of residual clove oil, benzocaine and tricaine in fish fillets using SPE and UPLC-DAD. J Adv Chem 10:2661\u20132668. https:\/\/doi.org\/10.24297\/jac.v10i5.6967","journal-title":"J Adv Chem"},{"key":"10739_CR43","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1016\/j.aquaculture.2014.04.032","volume":"432","author":"MC Portella","year":"2014","unstructured":"Portella MC, Jomori RK, Leit\u00e3o NJ, Menossi OCC, Freitas TM, Kojima JT, Lopes TS, Clavijo-Ayala JA, Carneiro DJ (2014) Larval development of indigenous South American freshwater fish species, with particular reference to pacu (Piaractus mesopotamicus): a review. Aquaculture 432:402\u2013417. https:\/\/doi.org\/10.1016\/j.aquaculture.2014.04.032","journal-title":"Aquaculture"},{"key":"10739_CR44","doi-asserted-by":"publisher","first-page":"1521","DOI":"10.3390\/ani11061521","volume":"11","author":"T Rairat","year":"2021","unstructured":"Rairat T, Chi Y, Hsieh CY, Liu YK, Chuchird N, Chou CC (2021) Determination of optimal doses and minimum effective concentrations of tricaine methanesulfonate, 2-phenoxyethanol and eugenol for laboratory managements in nile tilapia (Oreochromis niloticus). Animals 11:1521. https:\/\/doi.org\/10.3390\/ani11061521","journal-title":"Animals"},{"key":"10739_CR45","doi-asserted-by":"publisher","unstructured":"Rankin GO, Valentovic MA (2020) Target sites: kidney. In: Information resources in toxicology, Volume 1: Background, resources, and tools, pp 561\u2013564. https:\/\/doi.org\/10.1016\/B978-0-12-813724-6.00056-6","DOI":"10.1016\/B978-0-12-813724-6.00056-6"},{"key":"10739_CR46","doi-asserted-by":"publisher","first-page":"129012","DOI":"10.1016\/j.chemosphere.2020.129012","volume":"266","author":"M Rojo","year":"2020","unstructured":"Rojo M, Cristos D, Gonz\u00e1lez P, Lopez-Aca V, Domanico A, Carriquiriborde P (2020) Accumulation of human pharmaceuticals and activity of biotransformation enzymes in fish from two areas of the lower Rio de La Plata basin. Chemosphere 266:129012. https:\/\/doi.org\/10.1016\/j.chemosphere.2020.129012","journal-title":"Chemosphere"},{"key":"10739_CR47","doi-asserted-by":"crossref","unstructured":"Ross LG Ross B (2008) Anaesthetic and sedative techniques for aquatic animals. Blacwell","DOI":"10.1002\/9781444302264"},{"key":"10739_CR48","doi-asserted-by":"publisher","unstructured":"Rucinque DS, Polo G, Borb\u00f3n J, Mantilla JFG (2017) Anesthetic use of eugenol and benzocaine in juveniles of red tilapia (Oreochromis sp). Rev Colomb Cienc Pecuarias 30:60\u201366. https:\/\/doi.org\/10.17533\/udea.rccp.v30n1a07","DOI":"10.17533\/udea.rccp.v30n1a07"},{"key":"10739_CR49","first-page":"99541","volume-title":"Antimicrobial Immune Response","author":"S Sahoo","year":"2021","unstructured":"Sahoo S, Banu H, Prakash A, Tripathi G (2021) Immune system of fish: an evolutionary perspective. In: Ortega-Villaizan MDM, Chico V (eds) Antimicrobial immune response, 1st edn. IntechOpen, p 99541","edition":"1"},{"key":"10739_CR50","doi-asserted-by":"publisher","first-page":"2799","DOI":"10.5433\/1679-0359.2014v35n4Suplp2799","volume":"35","author":"MS Sanchez","year":"2014","unstructured":"Sanchez MS, dos Rodrigues S, Nunes RA, Oliveira AL, Fantini AMdaS, de Campos LE (2014) Effect of menthol and eugenol on the physiological responses of pacu Piaractus mesopotamicus. Semin Cienc Agrar 35:2799\u20132804. https:\/\/doi.org\/10.5433\/1679-0359.2014v35n4Suplp2799","journal-title":"Semin Cienc Agrar"},{"key":"10739_CR51","doi-asserted-by":"publisher","unstructured":"Sayed RKA, Zaccone G, Capillo G, Albano M, Mokhtar (2022) Structural and functional aspects of the spleen in molly fish Poecilia sphenops (Valenciennes, 1846): synergistic interactions of stem cells, neurons, and immune cells. Biol (Basel) 11:779. https:\/\/doi.org\/10.3390\/biology11050779","DOI":"10.3390\/biology11050779"},{"key":"10739_CR52","doi-asserted-by":"publisher","unstructured":"Schroeder P, Lloyd R, McKimm R, Metselaar M, Navarro J, O\u2019Farrell M, Readman GD, Speilberg L, Mocho JP (2021) Anaesthesia of laboratory, aquaculture and ornamental fish: proceedings of the first LASA-FVS symposium. Lab Anim 55:317\u2013338. https:\/\/doi.org\/10.1177\/0023677221998403","DOI":"10.1177\/0023677221998403"},{"key":"10739_CR53","doi-asserted-by":"publisher","first-page":"1827","DOI":"10.1002\/jps.10173","volume":"91","author":"I Segarra","year":"2002","unstructured":"Segarra I, Movshin DA, Zarif L (2002) Pharmacokinetics and tissue distribution after intravenous administration of a single dose of amphotericin B cochleates, a new lipid-based delivery system. J Pharm Sci 91:1827\u20131837. https:\/\/doi.org\/10.1002\/jps.10173","journal-title":"J Pharm Sci"},{"key":"10739_CR54","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1590\/S0101-20612007000300028","volume":"27","author":"MR Sim\u00f5es","year":"2007","unstructured":"Sim\u00f5es MR, Ribeiro CFA, Ribeiro SCA, Park KJ, Murr FEX (2007) Physicochemical and microbiological composition and yield of Thai-style tilapia fillets (Oreochromis niloticus). Food Sci Technol 27:608\u2013613","journal-title":"Food Sci Technol"},{"key":"10739_CR55","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1053\/j.jepm.2011.11.009","volume":"21","author":"LU Sneddon","year":"2012","unstructured":"Sneddon LU (2012) Clinical anesthesia and analgesia in fish. J Exot Pet Med 21:32\u201343. https:\/\/doi.org\/10.1053\/j.jepm.2011.11.009","journal-title":"J Exot Pet Med"},{"key":"10739_CR56","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1134\/S1995082920060139","volume":"14","author":"AA Soldatov","year":"2021","unstructured":"Soldatov AA (2021) Functional effects of the use of anesthetics on teleostean fishes: review. Inland Water Biol 14:67\u201377. https:\/\/doi.org\/10.1134\/S1995082920060139","journal-title":"Inland Water Biol"},{"key":"10739_CR57","doi-asserted-by":"publisher","first-page":"454552","DOI":"10.3389\/fphys.2019.00785","volume":"10","author":"C Souza","year":"2019","unstructured":"Souza C, de Baldissera F, Baldisserotto MD, Heinzmann B, Martos-Sitcha BM, Mancera JA JM (2019) Essential oils as stress-reducing agents for fish aquaculture: a review. Front Physiol 10:454552. https:\/\/doi.org\/10.3389\/fphys.2019.00785","journal-title":"Front Physiol"},{"key":"10739_CR58","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1046\/j.1365-2885.1998.00109.x","volume":"21","author":"GR Stehly","year":"1998","unstructured":"Stehly GR, Meinertz JR, Gingerich WH (1998) Effect of temperature on the pharmacokinetics of benzocaine in rainbow trout (Oncorhynchus mykiss) after bath exposures. J Vet Pharmacol Ther 21:121\u2013127. https:\/\/doi.org\/10.1046\/j.1365-2885.1998.00109.x","journal-title":"J Vet Pharmacol Ther"},{"key":"10739_CR59","volume-title":"Farmacocin\u00e9tica b\u00e1sica e Aplicada","author":"S Storpirtis","year":"2011","unstructured":"Storpirtis S, Gai MN, de Campos DR, Gon\u00e7alves JE (2011) Farmacocin\u00e9tica b\u00e1sica e aplicada, 1st edn. Guanabara Koogan, Rio de Janeiro","edition":"1"},{"key":"10739_CR60","doi-asserted-by":"publisher","first-page":"1152","DOI":"10.1039\/d2em00047d","volume":"24","author":"JM Sun","year":"2022","unstructured":"Sun JM, Kelly BC, Gobas FAPC, Sunderland EM (2022) A food web bioaccumulation model for the accumulation of per- and polyfluoroalkyl substances (PFAS) in fish: how important is renal elimination? Environ Sci Process Impacts 24:1152\u20131164. https:\/\/doi.org\/10.1039\/d2em00047d","journal-title":"Environ Sci Process Impacts"},{"key":"10739_CR61","doi-asserted-by":"publisher","first-page":"780","DOI":"10.1111\/jwas.12438","volume":"49","author":"A Tago","year":"2018","unstructured":"Tago A, Yokoyama S, Ishikawa M, Koshio S (2018) Pharmacokinetics of eugenol in Japanese flounder, Paralichthys olivaceus. J World Aquac Soc 49:780\u2013787. https:\/\/doi.org\/10.1111\/jwas.12438","journal-title":"J World Aquac Soc"},{"key":"10739_CR62","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1111\/j.1365-2885.2004.00600.x","volume":"27","author":"PL Toutain","year":"2004","unstructured":"Toutain PL, Bousquet-M\u00e9lou A (2004) Plasma terminal half-life. J Vet Pharmacol Ther 27:427\u2013439. https:\/\/doi.org\/10.1111\/j.1365-2885.2004.00600.x","journal-title":"J Vet Pharmacol Ther"},{"key":"10739_CR63","doi-asserted-by":"publisher","first-page":"100611","DOI":"10.1016\/j.aqrep.2021.100611","volume":"19","author":"WC Valenti","year":"2021","unstructured":"Valenti WC, Barros HP, Moraes-Valenti P, Bueno GW, Cavalli RO (2021) Aquaculture in Brazil: past, present and future. Aquac Rep 19:100611. https:\/\/doi.org\/10.1016\/j.aqrep.2021.100611","journal-title":"Aquac Rep"},{"key":"10739_CR64","first-page":"51","volume":"14","author":"AS Ventura","year":"2019","unstructured":"Ventura AS, Silva TS, de Zanon C, Inoue RB, Cardoso LAKA CAL (2019a) Pharmacokinetic and physiological responses of Piaractus mesopotamicus anesthetized with the essential oil of Lippia alba. Panam J Aquat Sci 14:51\u201360","journal-title":"Panam J Aquat Sci"},{"key":"10739_CR65","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s40071-019-0215-z","volume":"11","author":"AS Ventura","year":"2019","unstructured":"Ventura AS, Silva TS, de Zanon C, Inoue RB, Cardoso LAKA CAL (2019b) Physiological and pharmacokinetic responses in neotropical Piaractus mesopotamicus to the essential oil from Lippia Sidoides (Verbenaceae) as an anesthetic. Int Aquat Res 11:1\u201312. https:\/\/doi.org\/10.1007\/s40071-019-0215-z","journal-title":"Int Aquat Res"},{"key":"10739_CR66","doi-asserted-by":"publisher","unstructured":"Ventura AS, Jer\u00f4nimo GT, Oliveira SN de, Gabriel AM de A, Cardoso CAL, Teodoro GC, C\u00f4rrea Filho RAC, Povh JA\u00a0(2020) Natural anesthetics in the transport of Nile tilapia: hematological and biochemical responses and residual concentration in the fillet. Aquaculture 526:735365. https:\/\/doi.org\/10.1016\/j.aquaculture.2020.735365","DOI":"10.1016\/j.aquaculture.2020.735365"},{"key":"10739_CR67","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1007\/s11259-023-10225-8","volume":"48","author":"AS Ventura","year":"2023","unstructured":"Ventura AS, Corr\u00eaa Filho RAC, Cardoso CAL, Stringhetta GR, Brasileiro L, de O, Pereira SA, Jer\u00f4nimo GT, Povh JA (2023) Ocimum basilicum essential oil in Pacu Piaractus mesopotamicus: anesthetic efficacy, distribution, and depletion in different tissues. Vet Res Commun 48:685\u2013694. https:\/\/doi.org\/10.1007\/s11259-023-10225-8","journal-title":"Vet Res Commun"},{"key":"10739_CR68","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1016\/j.cbpc.2006.12.003","volume":"145","author":"SM Wu","year":"2007","unstructured":"Wu SM, Shih M-J, Ho Y-C (2007) Toxicological stress response and cadmium distribution in hybrid tilapia (Oreochromis sp.) upon cadmium exposure. Comp Biochem Physiol C Toxicol Pharmacol 145:218\u2013226. https:\/\/doi.org\/10.1016\/j.cbpc.2006.12.003","journal-title":"Comp Biochem Physiol C Toxicol Pharmacol"},{"key":"10739_CR69","doi-asserted-by":"publisher","first-page":"1097812","DOI":"10.3389\/fvets.2022.1097812","volume":"9","author":"Y Xu","year":"2023","unstructured":"Xu Y, Jiao Y, Yang J, Tan A, Ou D, Song X, Lv S (2023) The pharmacokinetic and residue depletion study of eugenol in carp (Cyprinus carpio). Front Vet Sci 9:1097812. https:\/\/doi.org\/10.3389\/fvets.2022.1097812","journal-title":"Front Vet Sci"},{"key":"10739_CR70","doi-asserted-by":"publisher","unstructured":"Ya\u015far T\u00d6, Yardimci M (2022) Trends towards the use of natural anesthetics in fish. J Istanbul Vet Sci 6:42\u201346. https:\/\/doi.org\/10.30704\/http-www-jivs-net.1089008","DOI":"10.30704\/http-www-jivs-net.1089008"},{"key":"10739_CR71","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1186\/s12917-017-1273-3","volume":"13","author":"DH Zhao","year":"2017","unstructured":"Zhao DH, Ke CL, Liu Q, Wang XF, Wang Q, Li LD (2017) Elimination kinetics of Eugenol in grass carp in a simulated transportation setting. BMC Vet Res 13:346. https:\/\/doi.org\/10.1186\/s12917-017-1273-3","journal-title":"BMC Vet Res"}],"container-title":["Veterinary Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11259-025-10739-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11259-025-10739-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11259-025-10739-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,8]],"date-time":"2025-05-08T08:21:26Z","timestamp":1746692486000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11259-025-10739-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,17]]},"references-count":71,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["10739"],"URL":"https:\/\/doi.org\/10.1007\/s11259-025-10739-3","relation":{},"ISSN":["0165-7380","1573-7446"],"issn-type":[{"type":"print","value":"0165-7380"},{"type":"electronic","value":"1573-7446"}],"subject":[],"published":{"date-parts":[[2025,4,17]]},"assertion":[{"value":"29 July 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 April 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 April 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"All the procedures performed were in accordance with the Brazilian National Council for Control of Animal Experimentation and the experimental protocol was approved by the Ethics Committee on the Use of Animals of the Federal University of Mato Grosso do Sul (UFMS), under protocol 976\/2018.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}}],"article-number":"168"}}