{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T02:15:31Z","timestamp":1782440131636,"version":"3.54.5"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T00:00:00Z","timestamp":1772236800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T00:00:00Z","timestamp":1772236800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100017595","name":"Universidade Feevale","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100017595","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Vet Res Commun"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The outbreak occurred in three farrowing rooms from a commercial farrow-to-wean farm with 4,600 sows located in southern Brazil. During the first week of outbreak, diarrhea and vomiting were recorded in sows, and inflammatory lesions were reported in neonatal piglets. Lesions were located on the tail, hock, perineal area, teats, vulva, male genital organs, sole, coronary band, ear, and jaw, which progressed to necrosis within few days. A total of 562 sows were evaluated for the presence of diarrhea and vomiting. Their litters, comprising 8,344 suckling piglets, were individually assessed for the presence, location and type of lesions. Laboratory analysis confirmed the presence of ergosterol in feed, which indicates a poor microbiological stability and fungal yeast invasion of the feed. Diarrhea was observed in 2.3% of sows. Overall, 38.2% (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u20093,190) of piglets presented lesions. In farrowing unit A, the tail and claw were the most frequently affected areas, whereas sole lesions predominated in room B and teat lesions in room C. Additionally, 12.0% of piglets born from sows with high genetic potential were not selected for replacement due to teats necrosis. This is the first case report of Swine Inflammation and Necrosis Syndrome (SINS) described outside Europe. Moreover, it highlights the importance of early diagnosis and feed monitoring for the prevention of mycotoxicosis in swine, to reduce their impacts on animal welfare, gilt selection for replacement, and removal of contaminated feed from the farm.\n                  <\/jats:p>","DOI":"10.1007\/s11259-026-11123-5","type":"journal-article","created":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T09:52:50Z","timestamp":1772272370000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Swine inflammation and necrosis syndrome outbreak in Brazil: a case report"],"prefix":"10.1007","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-7961-9748","authenticated-orcid":false,"given":"J\u00falia","family":"Berro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karoline Silveira","family":"Sperb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel","family":"Pola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola Reis","family":"Freimuth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brendha Lauren","family":"Fetter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela Teresa","family":"Schuh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas Mikael Ribeiro","family":"da Rosa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta Cristina","family":"Scheid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4901-1013","authenticated-orcid":false,"given":"Karine Ludwig","family":"Takeuti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,2,28]]},"reference":[{"issue":"3","key":"11123_CR1","doi-asserted-by":"publisher","first-page":"1007","DOI":"10.1007\/s00204-016-1794-8","volume":"91","author":"P Akbari","year":"2017","unstructured":"Akbari P, Braber S, Varasteh S, Alizadeh A, Garssen J, Fink-Gremmels J (2017) The intestinal barrier as an emerging target in the toxicological assessment of Mycotoxins. 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