{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T21:52:52Z","timestamp":1781646772060,"version":"3.54.5"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T00:00:00Z","timestamp":1774656000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T00:00:00Z","timestamp":1774656000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100010607","name":"Universit\u00e0 degli Studi di Perugia","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100010607","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Vet Res Commun"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Pericardial effusion is uncommon in cats and most often secondary to congestive heart failure, feline infectious peritonitis or neoplasia. Primary cardiac tumors are rare in companion animals, with their occurrence being particularly uncommon in cats and among these, mesothelioma is exceptionally rare. Its antemortem diagnosis presents a considerable challenge due to the often-mild nature of intrapericardial fluid accumulation and the difficulty in cytologically differentiating neoplastic cells from reactive mesothelial cells. A 12-year-old Domestic Shorthair cat was presented for dyspnea and weakness. Ultrasound examination revealed concurrent pleural, peritoneal and pericardial effusion. Pericardial effusion appeared densely particulate with multiple small nodules on the epicardial surface. Pericardiocentesis acutely resolved the cardiac tamponade, but recurrence prompted subtotal pericardiectomy. Histopathology of surgical biopsies suggested pericardial mesothelioma. Despite surgery, the cat\u2019s clinical condition deteriorated, leading to euthanasia one month later. Autopsy, histopathology and immunohistochemistry (positive for cytokeratin AE1\/AE3, vimentin, calretinin and HBME-1) confirmed pericardial mesothelioma with pleural dissemination. This report describes the clinical, diagnostic, and pathological features of a rare case of feline pericardial mesothelioma and highlights the diagnostic value of a multimodal approach.<\/jats:p>","DOI":"10.1007\/s11259-026-11172-w","type":"journal-article","created":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T05:29:18Z","timestamp":1774675758000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cardiac tamponade in a cat with pericardial mesothelioma"],"prefix":"10.1007","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4560-0371","authenticated-orcid":false,"given":"Fabio","family":"Spina","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6787-1300","authenticated-orcid":false,"given":"Margherita","family":"Orlandi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raffaele","family":"Preziosi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3544-8812","authenticated-orcid":false,"given":"Giuseppe","family":"Giglia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7613-6540","authenticated-orcid":false,"given":"Monica","family":"Sforna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Birettoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,3,28]]},"reference":[{"issue":"6","key":"11172_CR1","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1177\/1098612X13506199","volume":"16","author":"M Amati","year":"2014","unstructured":"Amati M, Venco L, Roccabianca P, Santagostino SF, Bertazzolo W (2014) Pericardial lymphoma in seven cats. 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The owner provided informed consent at the time of the diagnostic procedures.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Animal ethics approval"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"237"}}