{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:20:58Z","timestamp":1792783258329,"version":"4.5.0"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T00:00:00Z","timestamp":1780444800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T00:00:00Z","timestamp":1780444800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Universidade Federal De Santa Maria","id":[{"id":"https:\/\/ror.org\/01b78mz79","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Vet Res Commun"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    This study evaluated the safety and feasibility of gasless laparoscopic cholecystectomy in dogs, identifying factors associated with surgical time and survival. Twenty-five dogs with symptomatic gallbladder disease\u2014predominantly gallbladder mucocele (72.0%) and cholelithiasis\u2014underwent cholecystectomy using a mechanical abdominal wall lift system. Variables including gallbladder volume, age, body condition score, and intraoperative complications were recorded. Statistical analyses employed Pearson\u2019s chi-squared, Spearman\u2019s correlation, regression analysis for surgical time predictors, and Kaplan-Meier survival analysis with log-rank tests. No significant association was found between breed and biliary condition. However, surgical time was significantly and positively correlated with body weight and body condition score (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001). Linear regression indicated that each 1\u00a0kg increase in body weight added approximately 4\u00a0min to the procedure. Gallbladder volume did not correlate with surgical duration. Survival analysis revealed that dogs with gallbladder mucocele had a significantly lower probability of overall survival compared to cholelithiasis (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.014). The results demonstrate that the gasless laparoscopic cholecystectomy is a viable and safe alternative for canine patients, especially those at a high cardiorespiratory risk. While increased body weight is a critical predictor of prolonged surgery, the primary biliary pathology remains the most significant determinant of survival.\n                  <\/jats:p>","DOI":"10.1007\/s11259-026-11297-y","type":"journal-article","created":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T04:34:03Z","timestamp":1780461243000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Beyond pneumoperitoneum: technical feasibility and predictive factors for gasless laparoscopic cholecystectomy in dogs"],"prefix":"10.1007","volume":"50","author":[{"given":"Amanda Oliveira","family":"Paraguass\u00fa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ot\u00e1vio Henrique","family":"de Melo Schiefler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raquel","family":"Baumhardt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan A","family":"S\u00e1nchez-Margallo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco M","family":"S\u00e1nchez-Margallo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinicius","family":"da Silva Cadi\u00f1anos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel Satoru","family":"Ohashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franci\u00e9li Mallman","family":"Pozzobon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel Curvello","family":"de Mendon\u00e7a M\u00fcller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maur\u00edcio Veloso","family":"Brun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,6,3]]},"reference":[{"key":"11297_CR1","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1111\/j.1532-950X.2013.12025.x","volume":"42","author":"JA Bleedorn","year":"2013","unstructured":"Bleedorn JA, Dykema JL, Hardie RJ (2013) Minimally invasive surgery in veterinary practice: a 2010 survey of Diplomates and residents of the American College of Veterinary Surgeons. Vet Surg 42:635\u2013642. https:\/\/doi.org\/10.1111\/j.1532-950X.2013.12025.x","journal-title":"Vet Surg"},{"key":"11297_CR2","unstructured":"Brun MV, Sanchez-Margallo JA, Sanches-Margallo FM (2019) Multidirectional traction platform for gasless video surgery. Depositante: Brazil Patent BR 102019013473 A2 (Priority to ES 201800465 U)"},{"issue":"2","key":"11297_CR3","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1002\/vms3.675","volume":"8","author":"MV Brun","year":"2022","unstructured":"Brun MV, Sanchez-Margallo JA, Silva MAM, Sanchez-Margallo FM (2022) Use of a new device for gasless endosurgery in a laparoscopic diaphragmatic hernia repair ex vivo canine model: A per-clinical study. Vet Med Sci 8(2):460\u2013468. https:\/\/doi.org\/10.1002\/vms3.675","journal-title":"Vet Med Sci"},{"issue":"2","key":"11297_CR4","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1111\/vru.12120","volume":"55","author":"J Choi","year":"2014","unstructured":"Choi J, Kim A, Keh S, Oh J, Kim H, Yoon J (2014) Comparison between ultrasonographic and clinical findings in 43 dogs with gallbladder mucoceles. Vet Rad Ultrasound 55(2):202\u2013207. https:\/\/doi.org\/10.1111\/vru.12120","journal-title":"Vet Rad Ultrasound"},{"key":"11297_CR5","doi-asserted-by":"publisher","first-page":"298","DOI":"10.2460\/ajvr.69.2.298","volume":"69","author":"FM Duerr","year":"2008","unstructured":"Duerr FM, Twedt DC, Monnet E (2008) Changes in pH of Peritoneal Fluid Associated with Carbon Dioxide Insuflation During Laparoscopic Surgery in Dogs. Am J Vet Res 69:298\u2013301. https:\/\/doi.org\/10.2460\/ajvr.69.2.298","journal-title":"Am J Vet Res"},{"issue":"S1","key":"11297_CR6","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1111\/j.1532-950X.2014.12198.x","volume":"44","author":"BA Fransson","year":"2015","unstructured":"Fransson BA, Grubb TL, Perez TE, Flores K, Gay JM (2015) Cardiorespiratory changes and pain response of lift laparoscopy compared to capnoperitoneum laparoscopy in dogs. Vet Surg 44(S1):7\u201314. https:\/\/doi.org\/10.1111\/j.1532-950X.2014.12198.x","journal-title":"Vet Surg"},{"key":"11297_CR7","unstructured":"Galley M, Lang J, Mitchell M, Fletcher J (2022) Factors affecting survival in 516 dogs underwent cholecystectomy for treatment of gallbladder mucocele. The Can Vet J 63(1):63\u201366. https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8682924\/pdf\/cvj_01_63.pdf. Accessed 12 Nov 2025."},{"key":"11297_CR8","doi-asserted-by":"publisher","unstructured":"Gookin JL, Mathews KG, Seiler G (2025) Diagnosis and management of gallbladder mucocele formation in dogs. J Am Vet Med Assoc 263(6). https:\/\/doi.org\/10.2460\/javma.24.12.0789","DOI":"10.2460\/javma.24.12.0789"},{"issue":"4","key":"11297_CR9","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1111\/jsap.13468","volume":"63","author":"JA Jaffey","year":"2022","unstructured":"Jaffey JA (2022) Canine extrahepatic biliary disease. J Small Anim Pract 63(4):247\u2013264. https:\/\/doi.org\/10.1111\/jsap.13468","journal-title":"J Small Anim Pract"},{"issue":"11","key":"11297_CR10","doi-asserted-by":"publisher","first-page":"1747","DOI":"10.1292\/jvms.18-0266","volume":"80","author":"H Kanai","year":"2018","unstructured":"Kanai H, Hagiwara K, Nukaya A, Kondo M, Aso T (2018) Short-term outcome of laparoscopic cholecystectomy for benign gallbladder diseases in 76 dogs. 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Am J Vet Res 74:1340\u20131346. https:\/\/doi.org\/10.2460\/ajvr.74.10.1340","journal-title":"Am J Vet Res"},{"key":"11297_CR14","doi-asserted-by":"publisher","DOI":"10.29374\/2527-2179.bjvm000523","author":"V Milech","year":"2023","unstructured":"Milech V, Antunes BN, Caye P, Hartmann HF, Linhares MT, Cadin\u00e3nos VS, da Cunha TR, Diniz HC, Brun MV (2023) Gasless laparoscopic renal biopsy in canine cadavers: a preclinical study. Braz J Vet Med. https:\/\/doi.org\/10.29374\/2527-2179.bjvm000523","journal-title":"Braz J Vet Med"},{"issue":"3","key":"11297_CR15","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1111\/jvim.15611","volume":"25","author":"M Parkanzky","year":"2011","unstructured":"Parkanzky M, Grimes J, Schmiedt C, Secrest S, Bugbee A (2011) Long-term survival of dogs treated for gallbladder mucocele by cholecystectomy, medical management, or both. J Vet Int Med 25(3):319\u2013321. https:\/\/doi.org\/10.1111\/jvim.15611","journal-title":"J Vet Int Med"},{"issue":"10","key":"11297_CR16","doi-asserted-by":"publisher","first-page":"1615","DOI":"10.2460\/javma.2004.224.1615","volume":"224","author":"FS Pike","year":"2004","unstructured":"Pike FS, Berg J, King JNW, Penninck DG, Webster CRL (2004) Gallbladder mucocele in dogs: 30 cases (2000\u20132002). J Am Vet Med Assoc 224(10):1615\u20131622. https:\/\/doi.org\/10.2460\/javma.2004.224.1615","journal-title":"J Am Vet Med Assoc"}],"container-title":["Veterinary Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11259-026-11297-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11259-026-11297-y","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11259-026-11297-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T03:53:48Z","timestamp":1789790028000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11259-026-11297-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,3]]},"references-count":16,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["11297"],"URL":"https:\/\/doi.org\/10.1007\/s11259-026-11297-y","relation":{},"ISSN":["0165-7380","1573-7446"],"issn-type":[{"value":"0165-7380","type":"print"},{"value":"1573-7446","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,3]]},"assertion":[{"value":"17 February 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 May 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 June 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"All procedures were performed in accordance with the ethical standards of the institution. Informed consent was obtained from all owners for the surgical procedures and participation in the study. Some of the animals were part of a doctorate study, which protocol was reviewed and approved by the Ethics Committee on Animal Use (CEUA) of the Federal University of Santa Maria (UFSM) under protocol number n\u00ba 1637170325 (ID 004821).","order":1,"name":"Ethics","label":"State of Animal Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"361"}}