{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T05:36:54Z","timestamp":1792820214963,"version":"4.5.0"},"reference-count":81,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T00:00:00Z","timestamp":1790380800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T00:00:00Z","timestamp":1790380800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Vet Res Commun"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1007\/s11259-026-11523-7","type":"journal-article","created":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T03:07:55Z","timestamp":1790392075000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A methyl donor and an essential oil: Performance, economic efficiency, serum biochemistry, histomorphometry, and appetite\/growth-related gene expression in broilers"],"prefix":"10.1007","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2783-6962","authenticated-orcid":false,"given":"Olla A.","family":"Khalifa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9569-7522","authenticated-orcid":false,"given":"Seham F.","family":"Shehata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3161-661X","authenticated-orcid":false,"given":"Marwa I.","family":"Abdel-Haleem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3854-5917","authenticated-orcid":false,"given":"Maha","family":"Mamdouh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5834-4637","authenticated-orcid":false,"given":"Samar H.","family":"Baloza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,26]]},"reference":[{"key":"11523_CR1","doi-asserted-by":"publisher","DOI":"10.3390\/ani11123471","volume":"11","author":"N Abdelli","year":"2021","unstructured":"Abdelli N, Sola-Oriol D, Perez JF (2021) Phytogenic feed additives in poultry: achievements, prospective and challenges. Animals 11:3471. https:\/\/doi.org\/10.3390\/ani11123471","journal-title":"Animals"},{"key":"11523_CR2","doi-asserted-by":"publisher","first-page":"847","DOI":"10.5713\/ajas.2013.13644","volume":"27","author":"R Abou-Elkhair","year":"2014","unstructured":"Abou-Elkhair R, Ahmed H, Selim S (2014) Effects of black pepper (Piper nigrum), turmeric powder (Curcuma longa) and coriander seeds (Coriandrum sativum) and their combinations as feed additives on growth performance, carcass traits, some blood parameters and humoral immune response of broiler chickens. Asian Australas J Anim Sci 27:847. https:\/\/doi.org\/10.5713\/ajas.2013.13644","journal-title":"Asian Australas J Anim Sci"},{"key":"11523_CR3","doi-asserted-by":"publisher","DOI":"10.1093\/tas\/txad133","volume":"7","author":"FA Aderemi","year":"2023","unstructured":"Aderemi FA, Alabi OM (2023) Turmeric (Curcuma longa): an alternative to antibiotics in poultry nutrition. Transl Anim Sci 7:txad133. https:\/\/doi.org\/10.1093\/tas\/txad133","journal-title":"Transl Anim Sci"},{"key":"11523_CR4","doi-asserted-by":"publisher","first-page":"477","DOI":"10.3923\/ijps.2020.477.485","volume":"19","author":"N Akter","year":"2020","unstructured":"Akter N, Islam M, Hossain M et al (2020) Ascertaining the growth performance, ileal gut morphology, gastro-intestinal development and viability of broiler chicken fed l-methionine (L-Met) supplemented diet. Int J Poult Sci 19:477\u2013485. https:\/\/doi.org\/10.3923\/ijps.2020.477.485","journal-title":"Int J Poult Sci"},{"key":"11523_CR5","doi-asserted-by":"publisher","first-page":"2284686","DOI":"10.1080\/23311932.2023.2284686","volume":"9","author":"AA Al-Abdullatif","year":"2023","unstructured":"Al-Abdullatif AA, Qaid MM, Al-Mufarrej SI et al (2023) Impact of dietary supplementation with cinnamon bark powder on broiler growth and carcass indices, small intestinal measurements, physico-chemical properties of meat and economics of production. Cogent Food Agric 9:2284686. https:\/\/doi.org\/10.1080\/23311932.2023.2284686","journal-title":"Cogent Food Agric"},{"issue":"10","key":"11523_CR6","doi-asserted-by":"publisher","DOI":"10.1016\/j.psj.2025.105014","volume":"104","author":"MA Al-Garadi","year":"2025","unstructured":"Al-Garadi MA, Alhotan RA, Hussein EO et al (2025) Effects of a natural phytogenic feed additive on broiler performance, carcass traits, and gut health under diets with optimal and reduced energy and amino acid density. Poult Sci 105014. https:\/\/doi.org\/10.1016\/j.psj.2025.105014","journal-title":"Poult Sci"},{"key":"11523_CR7","doi-asserted-by":"publisher","DOI":"10.3390\/ani9030095","volume":"9","author":"AA Al-Sagheer","year":"2019","unstructured":"Al-Sagheer AA, Abd El-Hack ME, Alagawany M et al (2019) Paulownia leaves as a new feed resource: chemical composition and effects on growth, carcasses, digestibility, blood biochemistry, and intestinal bacterial populations of growing rabbits. Animals\u202f: an open access journal from MDPI 9:95. https:\/\/doi.org\/10.3390\/ani9030095","journal-title":"Animals : an open access journal from MDPI"},{"key":"11523_CR8","doi-asserted-by":"publisher","first-page":"e20230100","DOI":"10.37496\/rbz5320230100","volume":"53","author":"AH Alqhtani","year":"2024","unstructured":"Alqhtani AH, Al Sulaiman AR, Alharthi AS et al (2024) Growth performance and nutrient digestibility of broilers fed low-energy corn-soybean meal-based diets supplemented with an exogenous enzyme cocktail as a combined activity. Rev Bras Zootec 53:e20230100. https:\/\/doi.org\/10.37496\/rbz5320230100","journal-title":"Rev Bras Zootec"},{"key":"11523_CR9","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquaculture.2019.734301","volume":"512","author":"A Amin","year":"2019","unstructured":"Amin A, El Asely A, Abd El-Naby AS et al (2019) Growth performance, intestinal histomorphology and growth-related gene expression in response to dietary Ziziphus mauritiana in nile tilapia (Oreochromis niloticus). Aquaculture 512:734301. https:\/\/doi.org\/10.1016\/j.aquaculture.2019.734301","journal-title":"Aquaculture"},{"key":"11523_CR10","doi-asserted-by":"publisher","first-page":"R226","DOI":"10.1152\/ajpregu.1999.276.1.R226","volume":"276","author":"CM Ashwell","year":"1999","unstructured":"Ashwell CM, Czerwinski SM, Brocht DM et al (1999) Hormonal regulation of leptin expression in broiler chickens. Am J Physiol 276:R226\u2013232. https:\/\/doi.org\/10.1152\/ajpregu.1999.276.1.R226","journal-title":"Am J Physiol"},{"key":"11523_CR11","doi-asserted-by":"publisher","unstructured":"Aziz M, Zahra AE, Kheder Z et al (2019) The role of l. Methionine, l. Carnitine, choline and\/or silymarin in hepatoprotection against paracetamol intoxication and oxidative stress in broilers. Slov Vet Res 56. https:\/\/doi.org\/10.26873\/SVR-812-2019","DOI":"10.26873\/SVR-812-2019"},{"key":"11523_CR12","doi-asserted-by":"publisher","first-page":"675","DOI":"10.1590\/S0102-09352006000400035","volume":"58","author":"A Borsa","year":"2006","unstructured":"Borsa A, Kohayagawa A, Boretti L et al (2006) Serum levels of hepatic enzyme function in clinically healthy broiler chickens. Arq Bras Med Vet Zootec 58:675\u2013677. https:\/\/doi.org\/10.1590\/S0102-09352006000400035","journal-title":"Arq Bras Med Vet Zootec"},{"key":"11523_CR13","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2021.136230","volume":"764","author":"C Cao","year":"2021","unstructured":"Cao C, Gilbert ER, Cline MA (2021) DNA methylation-modifiers reduced food intake in juvenile chickens (Gallus gallus) and Japanese quail (Coturnix japonica). Neurosci Lett 764:136230. https:\/\/doi.org\/10.1016\/j.neulet.2021.136230","journal-title":"Neurosci Lett"},{"key":"11523_CR14","doi-asserted-by":"publisher","first-page":"420","DOI":"10.4314\/sajas.v41i4.13","volume":"41","author":"M Daneshyar","year":"2011","unstructured":"Daneshyar M, Ghandkanlo MA, Bayeghra FS et al (2011) Effects of dietary turmeric supplementation on plasma lipoproteins, meat quality and fatty acid composition in broilers. S Afr J Anim Sci 41:420\u2013428. https:\/\/doi.org\/10.4314\/sajas.v41i4.13","journal-title":"S Afr J Anim Sci"},{"key":"11523_CR15","doi-asserted-by":"publisher","first-page":"1098","DOI":"10.1016\/j.bbagen.2016.02.001","volume":"1860","author":"CR Day","year":"2016","unstructured":"Day CR, Kempson SA (2016) Betaine chemistry, roles, and potential use in liver disease. Biochim Biophys Acta 1860:1098\u20131106. https:\/\/doi.org\/10.1016\/j.bbagen.2016.02.001","journal-title":"Biochim Biophys Acta"},{"key":"11523_CR16","doi-asserted-by":"publisher","DOI":"10.1111\/asj.13991","volume":"95","author":"M dos Santos Mac\u00e1rio","year":"2024","unstructured":"dos Santos Mac\u00e1rio M, Del Vesco AP, Brito CO et al (2024) Turmeric essential oil improves intestinal integrity, immunological parameters, and performance of broiler chickens under cyclic heat stress. Anim Sci J 95:e13991. https:\/\/doi.org\/10.1111\/asj.13991","journal-title":"Anim Sci J"},{"key":"11523_CR17","doi-asserted-by":"publisher","unstructured":"El-Gogary M, Dorra TM, El-Sayed I (2025) Impact of dietary supplementation levels of turmeric powder (Curcuma longa) on performance, carcass characteristics, blood biochemical, jejunum histological and gut microflora in broiler chickens. J Anim Poult Prod 16. https:\/\/doi.org\/10.21608\/jappmu.2025.339434.1138","DOI":"10.21608\/jappmu.2025.339434.1138"},{"key":"11523_CR18","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1007\/s11250-022-03065-2","volume":"54","author":"HB El-Saway","year":"2022","unstructured":"El-Saway HB, Soliman MM, Sadek KM et al (2022) Beneficial impact of dietary methyl methionine sulfonium chloride and\/or L-carnitine supplementation on growth performance, feed efficiency, and serum biochemical parameters in broiler chicken: Role of IGF-1 and MSTN genes. Trop Anim Health Prod 54:98. https:\/\/doi.org\/10.1007\/s11250-022-03065-2","journal-title":"Trop Anim Health Prod"},{"key":"11523_CR19","doi-asserted-by":"publisher","first-page":"743","DOI":"10.5455\/javar.2022.i644","volume":"9","author":"SA El-Shobokshy","year":"2022","unstructured":"El-Shobokshy SA, Abo-Samaha MI, Abd El-Maksoud EM et al (2022) Influence of nano-methionine supplementation in drinking water on growth performance, lipid metabolism, and related gene expression in broiler chicken. J Adv Vet Anim Res 9:743. https:\/\/doi.org\/10.5455\/javar.2022.i644","journal-title":"J Adv Vet Anim Res"},{"key":"11523_CR20","doi-asserted-by":"publisher","DOI":"10.3390\/ani13233650","volume":"13","author":"NZ Eleiwa","year":"2023","unstructured":"Eleiwa NZ, El-Shabrawi AA, Ibrahim D et al (2023) Dietary curcumin modulating effect on performance, antioxidant status, and immune-related response of broiler chickens exposed to imidacloprid insecticide. Animals (Basel) 13:3650. https:\/\/doi.org\/10.3390\/ani13233650","journal-title":"Animals (Basel)"},{"key":"11523_CR21","doi-asserted-by":"publisher","first-page":"205","DOI":"10.54203\/scil.2023.wvj22","volume":"13","author":"D Engida","year":"2023","unstructured":"Engida D, Ayele M, Waktole H et al (2023) Effects of phytogenic feed additives on body weight gain and gut bacterial load in broiler chickens. Worlds Vet J 13:205\u2013213. https:\/\/doi.org\/10.54203\/scil.2023.wvj22","journal-title":"Worlds Vet J"},{"key":"11523_CR22","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0291998","volume":"18","author":"TM Felix","year":"2023","unstructured":"Felix TM, Souza CS, Santos SC et al (2023) Methionine sources at different dietary levels alters the growth and expression of genes related to homocysteine remethylation in the jejunum of broilers. PLoS One 18:e0291998. https:\/\/doi.org\/10.1371\/journal.pone.0291998","journal-title":"PLoS One"},{"key":"11523_CR23","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1016\/j.tem.2019.07.007","volume":"30","author":"M Friedman-Einat","year":"2019","unstructured":"Friedman-Einat M, Seroussi E (2019) Avian leptin: Bird\u2019s-eye view of the evolution of vertebrate energy-balance control. Trends Endocrinol Metab 30:819\u2013832. https:\/\/doi.org\/10.1016\/j.tem.2019.07.007","journal-title":"Trends Endocrinol Metab"},{"issue":"10","key":"11523_CR24","doi-asserted-by":"publisher","DOI":"10.1016\/j.psj.2025.105586","volume":"104","author":"E Ghashghaei","year":"2025","unstructured":"Ghashghaei E, Wang M, Mijiyawa A et al (2025) Effects of amino acids methionine, lysine, and taurine on feed intake and mRNA expression of appetite-related neuropeptides in layer-type chicks. Poult Sci 105586. https:\/\/doi.org\/10.1016\/j.psj.2025.105586","journal-title":"Poult Sci"},{"key":"11523_CR25","doi-asserted-by":"publisher","first-page":"780","DOI":"10.3109\/13880209.2015.1080731","volume":"54","author":"M Gholami-Ahangaran","year":"2016","unstructured":"Gholami-Ahangaran M, Rangsaz N, Azizi S (2016) Evaluation of turmeric (Curcuma longa) effect on biochemical and pathological parameters of liver and kidney in chicken aflatoxicosis. Pharm Biol 54:780\u2013787. https:\/\/doi.org\/10.3109\/13880209.2015.1080731","journal-title":"Pharm Biol"},{"key":"11523_CR26","doi-asserted-by":"publisher","first-page":"293","DOI":"10.21608\/avmj.2025.364281.1606","volume":"71","author":"AA Gomaa","year":"2025","unstructured":"Gomaa AA, Ahmed AI, Hussein MK et al (2025) Evaluation of some vaccination programs against newcastle disease virus in experimentally challenged broiler chickens. Assiut Vet Med J 71:293\u2013306. https:\/\/doi.org\/10.21608\/avmj.2025.364281.1606","journal-title":"Assiut Vet Med J"},{"key":"11523_CR27","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1016\/j.aninu.2023.07.004","volume":"15","author":"L Gong","year":"2023","unstructured":"Gong L, Mahmood T, Mercier Y et al (2023) Dietary methionine sources and levels modulate the intestinal health status of broiler chickens. Anim Nutr 15:242\u2013255. https:\/\/doi.org\/10.1016\/j.aninu.2023.07.004","journal-title":"Anim Nutr"},{"key":"11523_CR28","doi-asserted-by":"publisher","first-page":"293","DOI":"10.22358\/jafs\/78511\/2017","volume":"26","author":"J Guil-Guerrero","year":"2017","unstructured":"Guil-Guerrero J, Ramos L, Paredes JZ et al (2017) Effects of turmeric rhizome powder and curcumin in poultry production. A review. J Anim Feed Sci 26:293\u2013302. https:\/\/doi.org\/10.22358\/jafs\/78511\/2017","journal-title":"J Anim Feed Sci"},{"key":"11523_CR29","doi-asserted-by":"publisher","first-page":"958","DOI":"10.3390\/ani12080958","volume":"12","author":"MH Hafez","year":"2022","unstructured":"Hafez MH, El-Kazaz SE, Alharthi B et al (2022) The impact of curcumin on growth performance, growth-related gene expression, oxidative stress, and immunological biomarkers in broiler chickens at different stocking densities. Animals 12:958. https:\/\/doi.org\/10.3390\/ani12080958","journal-title":"Animals"},{"key":"11523_CR30","doi-asserted-by":"publisher","first-page":"321","DOI":"10.64252\/c2vjvz65","volume":"11","author":"AK Hassan","year":"2025","unstructured":"Hassan AK, Al-Zuhairi ZA (2025) Dietary methionine and broiler chicken growth: Evaluating performance and the GH\/IGF-I axis. Int J Environ Sci 11:321\u2013329","journal-title":"Int J Environ Sci"},{"key":"11523_CR31","doi-asserted-by":"publisher","first-page":"4471","DOI":"10.1002\/jsfa.8971","volume":"98","author":"X He","year":"2018","unstructured":"He X, Lu Z, Ma B et al (2018) Effects of chronic heat exposure on growth performance, intestinal epithelial histology, appetite-related hormones and genes expression in broilers. J Sci Food Agric 98:4471\u20134478. https:\/\/doi.org\/10.1002\/jsfa.8971","journal-title":"J Sci Food Agric"},{"key":"11523_CR32","doi-asserted-by":"publisher","unstructured":"Hrn\u010d\u00e1r C, FIk M, Hanusov\u00e1 E et al (2021) The effect of natural feed additive on productive performance of broiler chickens. Acta Fytotech Zootech 24. https:\/\/doi.org\/10.15414\/afz.2021.24.04.334-339","DOI":"10.15414\/afz.2021.24.04.334-339"},{"key":"11523_CR33","unstructured":"IBM Corp (2013) Ibm spss statistics for windows, version 22.0. Ibm corp., armonk, ny, USA. Google Search"},{"key":"11523_CR34","doi-asserted-by":"publisher","first-page":"txae127","DOI":"10.1093\/tas\/txae127","volume":"8","author":"OA Jimoh","year":"2024","unstructured":"Jimoh OA, Ayodele AD, Ojo OA et al (2024) Effects of turmeric, ginger, cinnamon, and garlic essential oils on HSP70, NF\u03baB, oxidative DNA damage, inflammatory cytokines, and oxidative markers in broiler chickens. Transl Anim Sci 8:txae127. https:\/\/doi.org\/10.1093\/tas\/txae127","journal-title":"Transl Anim Sci"},{"key":"11523_CR35","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1186\/s40104-023-00939-9","volume":"14","author":"X Ju","year":"2023","unstructured":"Ju X, Wang Z, Cai D et al (2023) DNA methylation in poultry: A review. J Anim Sci Biotechnol 14:138. https:\/\/doi.org\/10.1186\/s40104-023-00939-9","journal-title":"J Anim Sci Biotechnol"},{"key":"11523_CR36","doi-asserted-by":"publisher","DOI":"10.5455\/ajvs.233838","author":"E Kamel","year":"2016","unstructured":"Kamel E, Manaa E, Farid A (2016) The effects of dietary date pit on the productive and economic efficiency of Japanese quail. Alexandria J Vet Sci. https:\/\/doi.org\/10.5455\/ajvs.233838","journal-title":"Alexandria J Vet Sci"},{"key":"11523_CR37","doi-asserted-by":"publisher","first-page":"28","DOI":"10.52346\/rsr.2020.2.1.28","volume":"2","author":"D-W Kim","year":"2020","unstructured":"Kim D-W, Nho W-G, Kim S-H (2020) Efficacy of dietary supplementation of turmeric extract containing curcumin in broiler chicks. Resour Sci Res 2:28\u201338. https:\/\/doi.org\/10.52346\/rsr.2020.2.1.28","journal-title":"Resour Sci Res"},{"key":"11523_CR38","doi-asserted-by":"publisher","DOI":"10.3390\/ani11041170","volume":"11","author":"AA Kirrella","year":"2021","unstructured":"Kirrella AA, Abdo SE, El-Naggar K et al (2021) Use of corn silk meal in broiler diet: effect on growth performance, blood biochemistry, immunological responses, and growth-related gene expression. Animals 11:1170. https:\/\/doi.org\/10.3390\/ani11041170","journal-title":"Animals"},{"key":"11523_CR39","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2023.e13060","author":"C Kpomasse","year":"2023","unstructured":"Kpomasse C, Oso O, Lawal K et al (2023) Juvenile growth, thermotolerance and gut histomorphology of broiler chickens fed Curcuma longa under hot-humid environments. Heliyon. https:\/\/doi.org\/10.1016\/j.heliyon.2023.e13060","journal-title":"Heliyon"},{"key":"11523_CR40","doi-asserted-by":"publisher","unstructured":"Liang J, Zhao Y, Cheng Y et al (2025) Polyphenols, epigenetics, and methionine metabolism: Unlocking therapeutic potential. Crit Rev Food Sci Nutr 1\u201316. https:\/\/doi.org\/10.1080\/10408398.2025.2534843","DOI":"10.1080\/10408398.2025.2534843"},{"key":"11523_CR41","doi-asserted-by":"publisher","first-page":"2949","DOI":"10.3390\/ani13182949","volume":"13","author":"G Liu","year":"2023","unstructured":"Liu G, Kim WK (2023) The functional roles of methionine and arginine in intestinal and bone health of poultry. Animals 13:2949. https:\/\/doi.org\/10.3390\/ani13182949","journal-title":"Animals"},{"key":"11523_CR42","doi-asserted-by":"publisher","first-page":"878107","DOI":"10.3389\/fvets.2022.878107","volume":"9","author":"Y Liu","year":"2022","unstructured":"Liu Y, Wang D, Zhao L et al (2022) Effect of methionine deficiency on the growth performance, serum amino acids concentrations, gut microbiota and subsequent laying performance of layer chicks. Front Vet Sci 9:878107. https:\/\/doi.org\/10.3389\/fvets.2022.878107","journal-title":"Front Vet Sci"},{"key":"11523_CR43","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2022.850715","volume":"9","author":"JJ Luo","year":"2022","unstructured":"Luo JJ, Chen W, Qu H et al (2022) Dietary supplementation with yucca alleviates heat stress in growing broilers exposed to high ambient temperature. Front Vet Sci 9:850715. https:\/\/doi.org\/10.3389\/fvets.2022.850715","journal-title":"Front Vet Sci"},{"key":"11523_CR44","unstructured":"Mekchay S, Leotaragul A, Wongsa A et al (2005) Molecular marker-based genetic diversity assessment of thai native chicken and broiler chicken. Paper presented at the Conference on International Agricultural Research for Development, Tropentag, Stuttgart-Hohenheim"},{"key":"11523_CR45","doi-asserted-by":"publisher","unstructured":"Mohamed M, Hassan H (2023) Phytogenic substances as safe growth promoters in poultry nutrition. 12:89\u2013100. https:\/\/doi.org\/10.47278\/journal.ijvs\/2022.134","DOI":"10.47278\/journal.ijvs\/2022.134"},{"key":"11523_CR46","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1007\/s11259-021-09819-x","volume":"45","author":"LS Mohammed","year":"2021","unstructured":"Mohammed LS, Sallam EA, Edris SN et al (2021) Growth performance, economic efficiency, meat quality, and gene expression in two broiler breeds fed different levels of tomato pomace. Vet Res Commun 45:381\u2013397. https:\/\/doi.org\/10.1007\/s11259-021-09819-x","journal-title":"Vet Res Commun"},{"key":"11523_CR47","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1002\/ajmg.c.30293","volume":"157","author":"SH Mudd","year":"2011","unstructured":"Mudd SH (2011) Hypermethioninemias of genetic and non-genetic origin: A review. Am J Med Genet Part C Semin Med Genet 157:3\u201332. https:\/\/doi.org\/10.1002\/ajmg.c.30293","journal-title":"Am J Med Genet Part C Semin Med Genet"},{"key":"11523_CR48","first-page":"1112","volume":"34","author":"A Murray","year":"1984","unstructured":"Murray A (1984) Report on the symposium drug effect in clinical chemistry methods for estimation of ast. Eur J Clin Chem Clin Biochem 34:1112\u20131116","journal-title":"Eur J Clin Chem Clin Biochem"},{"key":"11523_CR49","doi-asserted-by":"publisher","first-page":"60","DOI":"10.3390\/dna5040060","volume":"5","author":"M Naeem","year":"2025","unstructured":"Naeem M, Fatima A (2025) Nutrigenomics and epigenetic regulation in poultry: DNA-based mechanisms linking diet to performance and health. DNA 5:60. https:\/\/doi.org\/10.3390\/dna5040060","journal-title":"DNA"},{"key":"11523_CR50","doi-asserted-by":"publisher","first-page":"247","DOI":"10.2141\/jpsa.0160141","volume":"54","author":"K Nakashima","year":"2017","unstructured":"Nakashima K, Ishida A, Shimamoto S et al (2017) Effects of insulin-like growth factor-i on the expression of atrogin-1\/MAFbx in chick myotube cultures. J Poult Sci 54:247\u2013252. https:\/\/doi.org\/10.2141\/jpsa.0160141","journal-title":"J Poult Sci"},{"key":"11523_CR51","doi-asserted-by":"publisher","DOI":"10.3390\/ani15192849","volume":"15","author":"UN Okonkwo","year":"2025","unstructured":"Okonkwo UN, Smit CJ, Egbu CF (2025) Mechanistic insights into the physiological and meat quality responses of broiler chickens fed incremental turmeric rhizome meal. Animals 15:2849. https:\/\/doi.org\/10.3390\/ani15192849","journal-title":"Animals"},{"key":"11523_CR52","doi-asserted-by":"publisher","first-page":"64","DOI":"10.25081\/jsa.2019.v3.5721","volume":"3","author":"S Olawumi","year":"2019","unstructured":"Olawumi S, Oyewole B, Okpe A et al (2019) Carcass characteristics and cost benefits of two broiler strains as affected by duration of feed withdrawal at finisher phase. J Sci Agric 3:64\u201367. https:\/\/doi.org\/10.25081\/jsa.2019.v3.5721","journal-title":"J Sci Agric"},{"key":"11523_CR53","doi-asserted-by":"publisher","DOI":"10.3844\/ajassp.2021.122.134","author":"SE Omogo","year":"2021","unstructured":"Omogo SE, Oparaji EH, Edeji FU (2021) Effect of feed additive supplementation on growth performance, intestinal morphology, intestinal microflora and nutrient digestibility study of broiler chicken. Am J Appl Sci. https:\/\/doi.org\/10.3844\/ajassp.2021.122.134","journal-title":"Am J Appl Sci"},{"key":"11523_CR54","doi-asserted-by":"publisher","DOI":"10.14719\/pst.3002","author":"VH Phan","year":"2024","unstructured":"Phan VH, Tran TT (2024) Effect of methionine on essential oil accumulation and antioxidant capacity of perilla (Perilla frutescens l.). Plant Sci Today. https:\/\/doi.org\/10.14719\/pst.3002","journal-title":"Plant Sci Today"},{"key":"11523_CR55","doi-asserted-by":"publisher","DOI":"10.3390\/ani11102839","volume":"11","author":"A Pokoo-Aikins","year":"2021","unstructured":"Pokoo-Aikins A, Timmons JR, Min BR et al (2021) Effects of feeding varying levels of DL-methionine on live performance and yield of broiler chickens. Animals (Basel) 11:2839. https:\/\/doi.org\/10.3390\/ani11102839","journal-title":"Animals (Basel)"},{"key":"11523_CR56","doi-asserted-by":"publisher","first-page":"40","DOI":"10.3390\/poultry1010005","volume":"1","author":"A Pokoo-Aikins","year":"2022","unstructured":"Pokoo-Aikins A, Timmons JR, Min BR et al (2022) Effects of varying levels of dietary DL-methionine supplementation on breast meat quality of male and female broilers. Poultry 1:40\u201353. https:\/\/doi.org\/10.3390\/poultry1010005","journal-title":"Poultry"},{"key":"11523_CR57","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1016\/j.ygcen.2017.10.009","volume":"255","author":"AMA Reid","year":"2018","unstructured":"Reid AMA, Dunn IC (2018) Gastrointestinal distribution of chicken gastrin-cholecystokinin family transcript expression and response to short-term nutritive state. Gen Comp Endocrinol 255:64\u201370. https:\/\/doi.org\/10.1016\/j.ygcen.2017.10.009","journal-title":"Gen Comp Endocrinol"},{"key":"11523_CR58","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0019524","volume":"6","author":"D Rengaraj","year":"2011","unstructured":"Rengaraj D, Lee BR, Lee SI et al (2011) Expression patterns and miRNA regulation of DNA methyltransferases in chicken primordial germ cells. PLoS One 6:e19524. https:\/\/doi.org\/10.1371\/journal.pone.0019524","journal-title":"PLoS One"},{"key":"11523_CR59","doi-asserted-by":"publisher","first-page":"907","DOI":"10.1093\/ps\/82.6.907","volume":"82","author":"M Richards","year":"2003","unstructured":"Richards M (2003) Genetic regulation of feed intake and energy balance in poultry. Poult Sci 82:907\u2013916. https:\/\/doi.org\/10.1093\/ps\/82.6.907","journal-title":"Poult Sci"},{"key":"11523_CR60","doi-asserted-by":"publisher","first-page":"182","DOI":"10.3382\/japr.2010-00167","volume":"19","author":"M Richards","year":"2010","unstructured":"Richards M, Rosebrough R, Coon C et al (2010) Feed intake regulation for the female broiler breeder: in theory and in practice. J Appl Poult Res 19:182\u2013193. https:\/\/doi.org\/10.3382\/japr.2010-00167","journal-title":"J Appl Poult Res"},{"key":"11523_CR61","doi-asserted-by":"publisher","first-page":"13","DOI":"10.2141\/jpsa.40.13","volume":"40","author":"K Sato","year":"2003","unstructured":"Sato K, Nishida M, Akiba Y (2003) Nutritional modulation of leptin messenger rna in broiler chickens. J Poult Sci 40:13\u201320. https:\/\/doi.org\/10.2141\/jpsa.40.13","journal-title":"J Poult Sci"},{"key":"11523_CR62","first-page":"45","volume":"2","author":"R Sayrafi","year":"2011","unstructured":"Sayrafi R, Shahrooz R, Soltanalinejad F et al (2011) Histomorphometrical study of the prebiotic effects on intestine morphology and growth performance of broiler chickens. Vet Res Forum 2:45\u201351","journal-title":"Vet Res Forum"},{"key":"11523_CR63","doi-asserted-by":"publisher","first-page":"1101","DOI":"10.1038\/nprot.2008.73","volume":"3","author":"TD Schmittgen","year":"2008","unstructured":"Schmittgen TD, Livak KJ (2008) Analyzing real-time pcr data by the comparative CT method. Nat Protoc 3:1101\u20131108. https:\/\/doi.org\/10.1038\/nprot.2008.73","journal-title":"Nat Protoc"},{"key":"11523_CR64","doi-asserted-by":"publisher","first-page":"737","DOI":"10.1210\/en.2015-1634","volume":"157","author":"E Seroussi","year":"2016","unstructured":"Seroussi E, Cinnamon Y, Yosefi S et al (2016) Identification of the long-sought leptin in chicken and duck: expression pattern of the highly GC-rich avian leptin fits an autocrine\/paracrine rather than endocrine function. Endocrinology 157:737\u2013751. https:\/\/doi.org\/10.1210\/en.2015-1634","journal-title":"Endocrinology"},{"key":"11523_CR65","doi-asserted-by":"publisher","DOI":"10.5455\/ajvs.115295","author":"SF Shehata","year":"2021","unstructured":"Shehata SF, Sallam EA, Azam AE et al (2021) Effect of different dietary inclusion levels of mulberry leaves on productive traits, economic indices, and immunity of white and brown japanese quail. Alexandria J Vet Sci. https:\/\/doi.org\/10.5455\/ajvs.115295","journal-title":"Alexandria J Vet Sci"},{"key":"11523_CR66","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms10020395","volume":"10","author":"AA Shehata","year":"2022","unstructured":"Shehata AA, Yal\u00e7\u0131n S, Latorre JD et al (2022a) Probiotics, prebiotics, and phytogenic substances for optimizing gut health in poultry. Microorganisms 10:395. https:\/\/doi.org\/10.3390\/microorganisms10020395","journal-title":"Microorganisms"},{"key":"11523_CR67","doi-asserted-by":"publisher","DOI":"10.1007\/s11250-022-03382-6","volume":"54","author":"SF Shehata","year":"2022","unstructured":"Shehata SF, Baloza SH, Elsokary MM et al (2022b) Effect of stocking density and vitamin E or zinc supplementation on growth, physiology, gene expression, and economic efficiency of growing broiler chicks. Trop Anim Health Prod 54:403. https:\/\/doi.org\/10.1007\/s11250-022-03382-6","journal-title":"Trop Anim Health Prod"},{"key":"11523_CR68","doi-asserted-by":"publisher","first-page":"2977","DOI":"10.2527\/jas2015-8898","volume":"93","author":"Y Shen","year":"2015","unstructured":"Shen Y, Ferket P, Park I et al (2015) Effects of feed grade L-methionine on intestinal redox status, intestinal development, and growth performance of young chickens compared with conventional DL-methionine. J Anim Sci 93:2977\u20132986. https:\/\/doi.org\/10.2527\/jas2015-8898","journal-title":"J Anim Sci"},{"key":"11523_CR69","doi-asserted-by":"publisher","first-page":"1329","DOI":"10.56093\/ijans.v83i12.35815","volume":"83","author":"R Singh","year":"2013","unstructured":"Singh R, Mandal A, Biswas A (2013) Efficacy of DL-methionine in amelioration of aflatoxicosis in coloured broiler chicken. Indian J Anim Sci 83:1329\u20131334. https:\/\/doi.org\/10.56093\/ijans.v83i12.35815","journal-title":"Indian J Anim Sci"},{"key":"11523_CR70","doi-asserted-by":"publisher","first-page":"499","DOI":"10.5513\/JCEA01\/21.3.2745","volume":"21","author":"N Such","year":"2020","unstructured":"Such N, Moln\u00e1r A, Farkas V et al (2020) B\u00fazakorpa, valamint k\u00e9t egyt\u00e9nyez\u0151s probiotikum etet\u00e9se nem befoly\u00e1solta a termel\u00e9si param\u00e9tereket, azonban megv\u00e1ltoztatta a b\u00e9l egyes param\u00e9tereit brojlercsirk\u00e9k eset\u00e9ben. J Cent Eur Agric 21:499\u2013507. https:\/\/doi.org\/10.5513\/JCEA01\/21.3.2745","journal-title":"J Cent Eur Agric"},{"key":"11523_CR71","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1093\/japr\/15.1.58","volume":"15","author":"P Waldroup","year":"2006","unstructured":"Waldroup P, Motl M, Yan F et al (2006) Effects of betaine and choline on response to methionine supplementation to broiler diets formulated to industry standards. J Appl Poult Res 15:58\u201371. https:\/\/doi.org\/10.1093\/japr\/15.1.58","journal-title":"J Appl Poult Res"},{"key":"11523_CR72","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0114236","volume":"9","author":"C Wen","year":"2014","unstructured":"Wen C, Chen Y, Wu P et al (2014) MSTN, mTOR and FoxO4 are involved in the enhancement of breast muscle growth by methionine in broilers with lower hatching weight. PLoS One 9:e114236. https:\/\/doi.org\/10.1371\/journal.pone.0114236","journal-title":"PLoS One"},{"key":"11523_CR73","doi-asserted-by":"publisher","first-page":"195","DOI":"10.2141\/jpsa.0180072","volume":"56","author":"SS Wickramasuriya","year":"2019","unstructured":"Wickramasuriya SS, Kim E, Cho H-M et al (2019) Differential effects of dietary methionine isomers on broilers challenged with acute heat stress. J Poult Sci 56:195\u2013203. https:\/\/doi.org\/10.2141\/jpsa.0180072","journal-title":"J Poult Sci"},{"key":"11523_CR74","doi-asserted-by":"publisher","first-page":"101128","DOI":"10.1016\/j.aqrep.2022.101128","volume":"24","author":"MJ Xavier","year":"2022","unstructured":"Xavier MJ, Navarro-Guill\u00e9n C, Lopes A et al (2022) Effects of dietary curcumin in growth performance, oxidative status and gut morphometry and function of gilthead seabream postlarvae. Aquac Rep 24:101128. https:\/\/doi.org\/10.1016\/j.aqrep.2022.101128","journal-title":"Aquac Rep"},{"key":"11523_CR75","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0102204","volume":"9","author":"J Xie","year":"2014","unstructured":"Xie J, Tang L, Lu L et al (2014) Differential expression of heat shock transcription factors and heat shock proteins after acute and chronic heat stress in laying chickens (Gallus gallus). PLoS One 9:e102204. https:\/\/doi.org\/10.1371\/journal.pone.0102204","journal-title":"PLoS One"},{"key":"11523_CR76","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1186\/s12864-021-08268-9","volume":"23","author":"M Yang","year":"2022","unstructured":"Yang M, Hu B, Sun D et al (2022) Growth hormone receptor gene influences mitochondrial function and chicken lipid metabolism by AMPK-PGC1\u03b1-PPAR signaling pathway. BMC Genomics 23:219. https:\/\/doi.org\/10.1186\/s12864-021-08268-9","journal-title":"BMC Genomics"},{"issue":"10","key":"11523_CR77","doi-asserted-by":"publisher","DOI":"10.1016\/j.psj.2025.105630","volume":"104","author":"P Yang","year":"2025","unstructured":"Yang P, Xiang M, Xu M et al (2025) Hvt-delivered chicken IGF-1 improves growth performance in broilers. Poult Sci 105630. https:\/\/doi.org\/10.1016\/j.psj.2025.105630","journal-title":"Poult Sci"},{"key":"11523_CR78","doi-asserted-by":"publisher","first-page":"910","DOI":"10.1002\/cbin.10466","volume":"39","author":"M Yu","year":"2015","unstructured":"Yu M, Wang H, Xu Y et al (2015) Insulin like growth factor1 (IGF-1) promotes myoblast proliferation and skeletal muscle growth of embryonic chickens via the PI3K\/Akt signalling pathway. Cell Biol Int 39:910\u2013922. https:\/\/doi.org\/10.1002\/cbin.10466","journal-title":"Cell Biol Int"},{"key":"11523_CR79","doi-asserted-by":"crossref","unstructured":"Yurina N, Khorin B, Yurin D et al (2020) The effect of feeding a natural feed additive on the performance of broiler chickens. Paper presented at the E3S Web of Conferences","DOI":"10.1051\/e3sconf\/202017504001"},{"key":"11523_CR80","doi-asserted-by":"publisher","first-page":"2008","DOI":"10.5713\/ajas.19.0967","volume":"33","author":"Y Zhang","year":"2020","unstructured":"Zhang Y, Liu Y, Li J et al (2020) Dietary corn resistant starch regulates intestinal morphology and barrier functions by activating the notch signaling pathway of broilers. Asian-Australas J Anim Sci 33:2008\u20132020. https:\/\/doi.org\/10.5713\/ajas.19.0967","journal-title":"Asian-Australas J Anim Sci"},{"key":"11523_CR81","doi-asserted-by":"publisher","DOI":"10.1016\/j.psj.2023.103382","volume":"103","author":"J Zhang","year":"2024","unstructured":"Zhang J, Geng S, Zhu Y et al (2024) Effects of dietary methionine supplementation on the growth performance, immune responses, antioxidant capacity, and subsequent development of layer chicks. Poult Sci 103:103382. https:\/\/doi.org\/10.1016\/j.psj.2023.103382","journal-title":"Poult Sci"}],"container-title":["Veterinary Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11259-026-11523-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11259-026-11523-7","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11259-026-11523-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T04:43:15Z","timestamp":1792816995000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11259-026-11523-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,26]]},"references-count":81,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,12]]}},"alternative-id":["11523"],"URL":"https:\/\/doi.org\/10.1007\/s11259-026-11523-7","relation":{},"ISSN":["0165-7380","1573-7446"],"issn-type":[{"value":"0165-7380","type":"print"},{"value":"1573-7446","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,26]]},"assertion":[{"value":"17 April 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 September 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 September 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The study was authorized by Benha University\u2019s Faculty of Veterinary Medicine Animal Ethics Committee (BUFVTM 21-09-25).","order":1,"name":"Ethics","label":"Ethics Approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not relevant.","order":2,"name":"Ethics","label":"Publication Authorization","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was approved by the institutional animal ethics committee (BUFVTM 21-09-25).","order":3,"name":"Ethics","label":"Consent","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"595"}}